moxestrol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
estrogens	3366	34816-55-2

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

moxestrol
moxestrel
moxesterol
RU-16117
RU 16117

Molecular weight: 326.44
Formula: C21H26O3
CLOGP: 2.46
LIPINSKI: 0
HAC: 3
HDO: 2
TPSA: 49.69
ALOGS: -4.55
ROTB: 1

Drug dosage:

None

ADMET properties:

Property	Value	Reference
BA (Bioavailability)	33 %	Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	G03CB04	GENITO URINARY SYSTEM AND SEX HORMONES SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM ESTROGENS Synthetic estrogens, plain
MeSH PA	D004965	Estrogen Antagonists
MeSH PA	D006727	Hormone Antagonists

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	11.11	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Estrogen receptor	Nuclear hormone receptor	P03372 Q92731	ESR1_HUMAN ESR2_HUMAN		IC50	8.60		CHEMBL

External reference:

ID	Source
C0066834	UMLSCUI
CHEBI:34857	CHEBI
CHEMBL1628161	ChEMBL_ID
DB13418	DRUGBANK_ID
C011310	MESH_SUPPLEMENTAL_RECORD_UI
11954041	PUBCHEM_CID
2913	INN_ID
61665-15-4	SECONDARY_CAS_RN
6923NT44OW	UNII

Pharmaceutical products:

None