meobentine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3340 46464-11-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • meobentine sulfate
  • meobentine
  • Molecular weight: 207.28
  • Formula: C11H17N3O
  • CLOGP: 1.42
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 45.65
  • ALOGS: -2.19
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK1,JAK2,MAP3K21,MAP3K7,MAPK7,MAPK9,MARK4,MET,MTOR,NTRK2,PAK4,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 48
kinase-selectivity-class EIF2AK3,GRK2,PDK4 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.96 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04920 KEGG_DRUG
58503-79-0 SECONDARY_CAS_RN
C0065952 UMLSCUI
CHEMBL2110972 ChEMBL_ID
CHEMBL3989783 ChEMBL_ID
42765 PUBCHEM_CID
C032896 MESH_SUPPLEMENTAL_RECORD_UI
4194 INN_ID
T91E239Z1V UNII
CHEBI:134874 CHEBI

Pharmaceutical products:

None