benzyl alcohol indications/contra

Stem definitionDrug idCAS RN
334 100-51-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • benzyl alcohol
  • benzenemethanol
  • phenylmethanol
  • phenylcarbinol
  • hydroxytoluene
A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
  • Molecular weight: 108.14
  • Formula: C7H8O
  • CLOGP: 1.10
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -0.61
  • ROTB: 1

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
April 9, 2009 FDA SHIONOGI INC

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC P03AX06 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES
Other ectoparasiticides, incl. scabicides
CHEBI has role CHEBI:46787 solvent
CHEBI has role CHEBI:48318 fragrance
FDA EPC N0000181811 Pediculicide
MeSH PA D000777 Anesthetics
MeSH PA D000779 Anesthetics, Local
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use (View source of the data)

scroll-->
DiseaseRelationSNOMED_IDDOID
Skin irritation indication 367466007
Itching of skin indication 418363000
Peptic ulcer contraindication 13200003 DOID:750
Chronic obstructive lung disease contraindication 13645005 DOID:3083
Hyperthyroidism contraindication 34486009 DOID:7998
Hypertensive disorder contraindication 38341003 DOID:10763
Contact dermatitis contraindication 40275004 DOID:2773
Coronary arteriosclerosis contraindication 53741008 DOID:3393
Diabetes mellitus contraindication 73211009 DOID:9351
Chronic idiopathic constipation contraindication 82934008
Open wound contraindication 125643001
Gastrointestinal obstruction contraindication 126765001
Bladder outflow obstruction contraindication 236645006
Benign prostatic hyperplasia contraindication 266569009 DOID:2883
Retention of urine contraindication 267064002
Angle-closure glaucoma contraindication 392291006 DOID:13550
Hypertensive urgency contraindication 443482000

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

scroll-->
Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
5% ULESFIA SHIONOGI INC N022129 April 9, 2009 RX LOTION TOPICAL 6793931 July 11, 2022 TOPICAL TREATMENT OF LICE INFESTATIONS
5% ULESFIA SHIONOGI INC N022129 April 9, 2009 RX LOTION TOPICAL 7294342 May 19, 2024 TOPICAL TREATMENT OF LICE INFESTATIONS

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

scroll-->
IDSource
CHEBI:17987 CHEBI
4017798 VUID
N0000146159 NUI
C0005100 UMLSCUI
D00077 KEGG_DRUG
CHEMBL720 ChEMBL_ID
4017798 VANDF
4017445 VANDF
NOCODE MMSL
11807 MMSL
N0000146159 NDFRT
N0000145833 NDFRT
N0000006750 NDFRT
1426 RXNORM
400850005 SNOMEDCT_US
55902002 SNOMEDCT_US
003192 NDDF
DB06770 DRUGBANK_ID
LKG8494WBH UNII
923 INN_ID
D019905 MESH_DESCRIPTOR_UI
244 PUBCHEM_CID
010 PDB_CHEM_ID

Pharmaceutical products:

scroll-->
ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
ITCH X HUMAN OTC DRUG LABEL 2 0225-0495 GEL 10 g TOPICAL OTC monograph not final 13 sections
ITCH-X HUMAN OTC DRUG LABEL 2 0225-0516 SPRAY 10 g TOPICAL OTC monograph not final 13 sections
Ivarest HUMAN OTC DRUG LABEL 3 10157-9077 CREAM 10.50 g TOPICAL OTC MONOGRAPH FINAL 8 sections
Orajel Toothache Rinse HUMAN OTC DRUG LABEL 2 10237-764 LIQUID 2.91 mg TOPICAL OTC monograph not final 11 sections
Nitrotan HUMAN OTC DRUG LABEL 4 11960-0049 AEROSOL, SPRAY 0.06 g TOPICAL OTC monograph not final 9 sections
shing-Releev HUMAN OTC DRUG LABEL 3 15478-005 LIQUID 5 mL TOPICAL OTC monograph not final 8 sections
Cipro HC HUMAN PRESCRIPTION DRUG LABEL 3 16590-053 SUSPENSION 9 mg AURICULAR (OTIC) NDA 9 sections
Ulesfia HUMAN PRESCRIPTION DRUG LABEL 1 23594-780 LOTION 50 mg TOPICAL NDA 17 sections
Ivy-Dry Super HUMAN OTC DRUG LABEL 3 49546-105 SPRAY 100 mg TOPICAL OTC monograph not final 7 sections
Ivy-Dry Super HUMAN OTC DRUG LABEL 3 49546-106 SPRAY 100 mg TOPICAL OTC monograph not final 7 sections
Ivy Dry HUMAN OTC DRUG LABEL 3 49546-201 CREAM 10 g TOPICAL OTC monograph not final 8 sections
Zilactin HUMAN OTC DRUG LABEL 1 50486-468 GEL 0.10 g TOPICAL OTC monograph final 9 sections
AVERTEAX HUMAN OTC DRUG LABEL 1 54866-002 CREAM 10 mg TOPICAL OTC monograph not final 11 sections
Cipro HUMAN PRESCRIPTION DRUG LABEL 3 54868-4365 SUSPENSION 9 mg AURICULAR (OTIC) NDA 10 sections
Salonpas LIDOCAINE PLUS HUMAN OTC DRUG LABEL 1 55328-901 LIQUID 10 g TOPICAL OTC monograph not final 9 sections
Salonpas LIDOCAINE PLUS HUMAN OTC DRUG LABEL 1 55328-902 CREAM 10 g TOPICAL OTC monograph not final 9 sections
Orajel Toothache Rinse HUMAN OTC DRUG LABEL 2 62864-764 LIQUID 2.91 mg TOPICAL OTC monograph not final 11 sections
shing-Releev HUMAN OTC DRUG LABEL 3 63287-420 LIQUID 5 mg TOPICAL OTC monograph not final 8 sections
biochemistry PAIN RELIEF FOOT ACTIVE HUMAN OTC DRUG LABEL 1 65121-209 LIQUID 190 mg TOPICAL OTC monograph not final 7 sections
Ulesfia HUMAN PRESCRIPTION DRUG LABEL 1 69202-780 LOTION 50 mg TOPICAL NDA 17 sections
Protocoxil HUMAN OTC DRUG LABEL 1 71416-001 GEL 100 mg TOPICAL OTC monograph not final 8 sections
Protocoxil HUMAN OTC DRUG LABEL 1 71416-002 GEL 100 mg TOPICAL OTC monograph not final 8 sections