oxilofrine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
sympathomimetic, phenethyl derivatives 3286 365-26-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxilofrine
  • oxilofrine hydrochloride
  • oxilofrine HCl
  • Molecular weight: 181.24
  • Formula: C10H15NO2
  • CLOGP: 0.22
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 3
  • TPSA: 52.49
  • ALOGS: -1.17
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK7,MAPKAPK2,NTRK2,PDK2,PDK4,PIM2,PRKDC,SIK2,STK33,SYK,TEK,TGFBR1,ZAP70 33
kinase-selectivity-class CDK4,EIF2AK3,EPHB4,GRK2,MAP2K6 5
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.52 acidic
pKa2 9.22 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
F49638UBDR UNII
D08314 KEGG_DRUG
942-51-8 SECONDARY_CAS_RN
C0069766 UMLSCUI
CHEBI:134822 CHEBI
CHEMBL30400 ChEMBL_ID
688009 PUBCHEM_CID
DB11610 DRUGBANK_ID
4665 INN_ID
C026055 MESH_SUPPLEMENTAL_RECORD_UI
236554 RXNORM
003462 NDDF
006275 NDDF
F49638UBDR INXIGHT DRUGS

Pharmaceutical products:

None