formaldehyde indications/contra

Stem definitionDrug idCAS RN
3244 50-00-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • formol
  • formaldehyde
  • formalin
A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
  • Molecular weight: 30.03
  • Formula: CH2O
  • CLOGP: 0.35
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA: 17.07
  • ALOGS: 0.82
  • ROTB: 0

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D000890 Anti-Infective Agents
MeSH PA D004202 Disinfectants
MeSH PA D005404 Fixatives
FDA EPC N0000185508 Standardized Chemical Allergen
FDA PE N0000175629 Increased Histamine Release
FDA PE N0000184306 Cell-mediated Immunity
FDA Chemical/Ingredient N0000171131 Allergens

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Influenza indication 6142004 DOID:8469

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
CHEBI:16842 CHEBI
4019061 VUID
N0000147328 NUI
C0016564 UMLSCUI
D00017 KEGG_DRUG
1HG84L3525 UNII
286 MMSL
4530 RXNORM
111095003 SNOMEDCT_US
4763 MMSL
4019061 VANDF
N0000147328 NDFRT
N0000006222 NDFRT
003204 NDDF
332436004 SNOMEDCT_US
CHEMBL1255 ChEMBL_ID
D005557 MESH_DESCRIPTOR_UI
DB03843 DRUGBANK_ID
712 PUBCHEM_CID

Pharmaceutical products:

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ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
Formadon HUMAN PRESCRIPTION DRUG LABEL 1 10481-1050 LIQUID 0.10 mL TOPICAL unapproved drug other 4 sections
Forma-Ray HUMAN PRESCRIPTION DRUG LABEL 1 10481-3015 LIQUID 0.20 mL TOPICAL unapproved drug other 5 sections
FORMALDEHYDE HUMAN PRESCRIPTION DRUG LABEL 1 49908-167 SOLUTION 100 mg TOPICAL unapproved drug other 6 sections