fluroxene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
halogenated compounds used as general inhalation anaesthetics 3242 406-90-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • fluroxene
  • fluoromar
  • fluoroxene
  • trifluoroethyl vinyl ether
  • Molecular weight: 126.08
  • Formula: C4H5F3O
  • CLOGP: 1.46
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA: 9.23
  • ALOGS: -1.05
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AURKA,AXL,BRAF,BTK,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK3,MAP2K6,MAP3K7,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CG,PRKDC,STK33,SYK,TEK,TTK 36
kinase-selectivity-class PDK1,PDK2 2
pfas-class PFAS structural alert (1 = True, 0 = False) 1

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
General anesthesia indication 50697003




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04237 KEGG_DRUG
C0016381 UMLSCUI
CHEBI:134757 CHEBI
CHEMBL141446 ChEMBL_ID
9844 PUBCHEM_CID
1278 INN_ID
C084587 MESH_SUPPLEMENTAL_RECORD_UI
FO7JHA3G03 UNII
001397 NDDF

Pharmaceutical products:

None