Stem definition | Drug id | CAS RN |
---|---|---|
3201 | 487-79-6 |
None
None
None
None
None
None
None
Source | Code | Description |
---|---|---|
MeSH PA | D000871 | Anthelmintics |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D000969 | Antinematodal Agents |
MeSH PA | D000977 | Antiparasitic Agents |
MeSH PA | D018690 | Excitatory Amino Acid Agonists |
MeSH PA | D018377 | Neurotransmitter Agents |
CHEBI has role | CHEBI:35444 | antinematodal drugs |
CHEBI has role | CHEBI:50103 | excitatory amino acid agonists |
None
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 1.88 | acidic |
pKa2 | 4.44 | acidic |
pKa3 | 9.94 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 | GPCR | IC50 | 7.11 | CHEMBL | |||||
Glutamate receptor 1 | Ion channel | Ki | 5.13 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 1 | Ion channel | Ki | 6.75 | CHEMBL | |||||
Glutamate receptor 2 | Ion channel | Ki | 4.91 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 5 | Ion channel | Ki | 8.10 | CHEMBL | |||||
Glutamate receptor 4 | Ion channel | Ki | 5.77 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 2 | Ion channel | Ki | 7.49 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 3 | Ion channel | Ki | 8 | CHEMBL | |||||
Glutamate receptor 3 | Ion channel | Ki | 5.58 | PDSP | |||||
Glutamate receptor ionotropic, kainate 4 | Ion channel | Ki | 8.64 | PDSP | |||||
Glutamate receptor 2 | Ion channel | Ki | 5.43 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 2 | Ion channel | Ki | 8.43 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 1 | Ion channel | Ki | 7.15 | CHEMBL | |||||
Glutamate receptor 1 | Ion channel | Ki | 6.32 | CHEMBL | |||||
Glutamate receptor 3 | Ion channel | Ki | 5.70 | CHEMBL | |||||
Glutamate receptor 4 | Ion channel | Ki | 5.45 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 4 | Ion channel | Ki | 8.33 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 5 | Ion channel | Ki | 7.82 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate 3 | Ion channel | Ki | 8.42 | CHEMBL | |||||
Glutamate receptor ionotropic, AMPA | Ion channel | Ki | 7.53 | CHEMBL | |||||
Glutamate receptor ionotropic, kainate | Ion channel | IC50 | 8.37 | CHEMBL |
ID | Source |
---|---|
D02546 | KEGG_DRUG |
C0022471 | UMLSCUI |
CHEBI:31746 | CHEBI |
CHEMBL275040 | ChEMBL_ID |
D007608 | MESH_DESCRIPTOR_UI |
10255 | PUBCHEM_CID |
1509 | INN_ID |
SIV03811UC | UNII |
006209 | NDDF |
KAI | PDB_CHEM_ID |
None