ethacridine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| acridine derivatives | 3194 | 442-16-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A topically applied anti-infective agent.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | B05CA08 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS IRRIGATING SOLUTIONS Antiinfectives |
| ATC | D08AA01 | DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Acridine derivatives |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000891 | Anti-Infective Agents, Local |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 10.96 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Telomerase reverse transcriptase | Enzyme | IC50 | 5.09 | CHEMBL | |||||
| Reverse transcriptase/RNaseH | Enzyme | IC50 | 4.70 | CHEMBL | |||||
| Reverse transcriptase | Enzyme | IC50 | 4.70 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000167269 | NUI |
| D07924 | KEGG_DRUG |
| 6402-23-9 | SECONDARY_CAS_RN |
| C0014960 | UMLSCUI |
| CHEBI:135032 | CHEBI |
| CHEMBL94007 | ChEMBL_ID |
| DB13190 | DRUGBANK_ID |
| CHEMBL2355915 | ChEMBL_ID |
| CHEMBL582355 | ChEMBL_ID |
| D004975 | MESH_DESCRIPTOR_UI |
| 2017 | PUBCHEM_CID |
| 1783 | INN_ID |
| WIX85M1A6R | UNII |
| 4106 | RXNORM |
| 005540 | NDDF |
| 005541 | NDDF |
| 711320003 | SNOMEDCT_US |
| 715469007 | SNOMEDCT_US |
Pharmaceutical products:
None