enilconazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
systemic antifungal agents, miconazole derivatives 3177 35554-44-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • enilconazole
  • imazalil
  • bromazil
  • deccozil
  • imazalil phosphate
  • imazalil sulfate
  • imazalil mononitrate
  • Molecular weight: 297.18
  • Formula: C14H14Cl2N2O
  • CLOGP: 3.65
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 27.05
  • ALOGS: -3.92
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:24527 herbicides
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:78298 environmental contaminants
MeSH PA D005659 Fungicides, Industrial
MeSH PA D010575 Pesticides
CHEBI has role CHEBI:77884 sterol 14alpha-demethylase inhibitor
CHEBI has role CHEBI:86328 anti-fungal agrichemical

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.49 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Indoleamine 2,3-dioxygenase 1 Enzyme IC50 4.64 CHEMBL

External reference:

IDSource
D03997 KEGG_DRUG
C0063371 UMLSCUI
CHEBI:81927 CHEBI
CHEMBL356918 ChEMBL_ID
C017435 MESH_SUPPLEMENTAL_RECORD_UI
37175 PUBCHEM_CID
4921 INN_ID
6K0NOF3XQ6 UNII
1442172 RXNORM

Pharmaceutical products:

None