benzarone indications/contra

Stem definitionDrug idCAS RN
antiarrhythmics 317 1477-19-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • benzarone
  • benzaron
antihemorrhagic agent; structure
  • Molecular weight: 266.30
  • Formula: C17H14O3
  • CLOGP: 4.64
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 50.44
  • ALOGS: -4.05
  • ROTB: 3

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D002317 Cardiovascular Agents
MeSH PA D050299 Fibrin Modulating Agents
MeSH PA D005343 Fibrinolytic Agents
MeSH PA D006401 Hematologic Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.12 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Solute carrier family 22 member 12 Transporter IC50 5.55 CHEMBL

External reference:

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IDSource
C0053152 UMLSCUI
23ZW4BG89C UNII
1426 INN_ID
255968 PUBCHEM_CID
18923 RXNORM
71380009 SNOMEDCT_US
CHEBI:34559 CHEBI
CHEMBL1474963 ChEMBL_ID
C004528 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None