bentiromide indications/contra

Stem definitionDrug idCAS RN
316 37106-97-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bentiromide
  • chymex
chymotrypsin labile peptide used diagnostically as an index of exocrine pancreas function
  • Molecular weight: 404.42
  • Formula: C23H20N2O5
  • CLOGP: 2.96
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 4
  • TPSA: 115.73
  • ALOGS: -4.99
  • ROTB: 7

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 29, 1983 FDA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC V04CK03 VARIOUS
DIAGNOSTIC AGENTS
OTHER DIAGNOSTIC AGENTS
Tests for pancreatic function
MeSH PA D007202 Indicators and Reagents
CHEBI has role CHEBI:33893 reagent
CHEBI has role CHEBI:47867 indicator
CHEBI has role CHEBI:33295 diagnostic agent

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Diagnostic Test for Pancreas Function indication

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.27 acidic
pKa2 8.99 acidic
pKa3 11.54 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
DB00522 DRUGBANK_ID
4018108 VUID
N0000146446 NUI
C0053122 UMLSCUI
D01346 KEGG_DRUG
239IF5W61J UNII
4424 INN_ID
4018108 VANDF
N0000146446 NDFRT
N0000006130 NDFRT
18896 RXNORM
001240 NDDF
6957673 PUBCHEM_CID
CHEMBL1200368 ChEMBL_ID
C006717 MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:31263 CHEBI

Pharmaceutical products:

None