benfotiamine indications/contra

Stem definitionDrug idCAS RN
308 22457-89-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • benfotiamine
  • benfothiamine
  • benzoylthiamine monophosphate
  • betivina
  • bietamine
  • Molecular weight: 466.45
  • Formula: C19H23N4O6PS
  • CLOGP: -0.62
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 3
  • TPSA: 155.94
  • ALOGS: -4.07
  • ROTB: 10

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC A11DA03 ALIMENTARY TRACT AND METABOLISM
VITAMINS
VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12
Vitamin B1, plain
CHEBI has role CHEBI:50847 immunological adjuvant
CHEBI has role CHEBI:50733 nutraceutical
CHEBI has role CHEBI:50267 protective agent

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.16 acidic
pKa2 6.98 acidic
pKa3 7.59 Basic
pKa4 0.96 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
4028227 VUID
N0000177939 NUI
C0053116 UMLSCUI
D01255 KEGG_DRUG
23417 MMSL
4028227 VANDF
N0000177939 NDFRT
18891 RXNORM
005583 NDDF
703399007 SNOMEDCT_US
704989003 SNOMEDCT_US
3032771 PUBCHEM_CID
CHEMBL1491875 ChEMBL_ID
DB11748 DRUGBANK_ID
Y92OUS2H9B UNII
1300 INN_ID
CHEBI:41039 CHEBI

Pharmaceutical products:

None