cefpimizole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, cefalosporanic acid derivatives 3075 84880-03-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cefpimizole sodium
  • cefpimizol
  • cefpimizole disodium
  • cefpimizole
semisynthetic cephalosporin
  • Molecular weight: 670.67
  • Formula: C28H26N6O10S2
  • CLOGP: -9.47
  • LIPINSKI: 2
  • HAC: 16
  • HDO: 5
  • TPSA: 242.87
  • ALOGS: -4.81
  • ROTB: 12

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 0.21 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 1.70 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 1.80 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.53 acidic
pKa2 2.25 acidic
pKa3 2.83 acidic
pKa4 10.52 acidic
pKa5 11.49 acidic
pKa6 0.91 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01568 KEGG_DRUG
85287-61-2 SECONDARY_CAS_RN
C0055009 UMLSCUI
CHEBI:31376 CHEBI
CHEMBL2103902 ChEMBL_ID
CHEMBL2106385 ChEMBL_ID
C038845 MESH_SUPPLEMENTAL_RECORD_UI
10779 IUPHAR_LIGAND_ID
5464 INN_ID
24S58UHU7N UNII
68597 PUBCHEM_CID

Pharmaceutical products:

None