benfluorex indications/contra

Stem definitionDrug idCAS RN
anorexics 307 23602-78-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • benfluorex methanesulfonate
  • benfluorex maleate
  • benfluorex
  • benfluramate
  • benfluorex hydrochloride
  • Molecular weight: 351.37
  • Formula: C19H20F3NO2
  • CLOGP: 4.89
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 38.33
  • ALOGS: -5.44
  • ROTB: 9

Drug dosage:

DoseUnitRoute
0.45 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC A10BX06 ALIMENTARY TRACT AND METABOLISM
DRUGS USED IN DIABETES
BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Other blood glucose lowering drugs, excl. insulins
MeSH PA D019440 Anti-Obesity Agents
MeSH PA D000963 Antimetabolites
MeSH PA D001067 Appetite Depressants
MeSH PA D002491 Central Nervous System Agents
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Type 2 diabetes mellitus in obese indication 81531005

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.57 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0053105 UMLSCUI
D07192 KEGG_DRUG
403FO0NQG3 UNII
3054 INN_ID
18880 RXNORM
004328 NDDF
719681008 SNOMEDCT_US
CHEMBL400599 ChEMBL_ID
2318 PUBCHEM_CID
CHEMBL1412305 ChEMBL_ID
DB09022 DRUGBANK_ID
23642-66-2 SECONDARY_CAS_RN
C001584 MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:93826 CHEBI

Pharmaceutical products:

None