bucolome 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
hypnotics, barbituric acid derivatives 3044 841-73-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • 1-cyclohexyl-5-butylbarbituric acid
  • bucolome
  • bucolom
  • paramidin
  • paramidine
  • Molecular weight: 266.34
  • Formula: C14H22N2O3
  • CLOGP: 3.09
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 66.48
  • ALOGS: -2.12
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug resistance 30.74 27.38 5 3 25922 34931001

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.86 acidic
pKa2 6.79 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01661 KEGG_DRUG
C0006339 UMLSCUI
CHEBI:31314 CHEBI
CHEMBL2106136 ChEMBL_ID
C084817 MESH_SUPPLEMENTAL_RECORD_UI
2461 PUBCHEM_CID
2284 INN_ID
9T08RAL174 UNII

Pharmaceutical products:

None