bisoctrizole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3031 103597-45-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bisoctrizole
  • bisoctyltriazole
  • Molecular weight: 658.89
  • Formula: C41H50N6O2
  • CLOGP: 12
  • LIPINSKI: 2
  • HAC: 8
  • HDO: 2
  • TPSA: 101.88
  • ALOGS: -6.16
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AURKB,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,JAK3,KIT,MAP2K6,MAP3K1,MAP3K10,MAP3K11,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ULK2,ZAP70 71
kinase-selectivity-class BRAF,CSF1R,FLT3,GRK2,MET,PDK4 6
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.09 acidic
pKa2 11.86 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03249 KEGG_DRUG
C1879850 UMLSCUI
CHEBI:135865 CHEBI
CHEMBL2104957 ChEMBL_ID
DB11262 DRUGBANK_ID
8586 INN_ID
8NT850T0YS UNII
3571576 PUBCHEM_CID
1310510 RXNORM
015430 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
OHUI Sun Science Powder Sun Block Natural Skin HUMAN OTC DRUG LABEL 4 53208-437 POWDER 2 g TOPICAL OTC monograph not final 6 sections
Whoo Gong Jin Hyang Jin Hae Yoon Sun HUMAN OTC DRUG LABEL 4 53208-513 POWDER 2.13 g TOPICAL OTC monograph not final 6 sections
Absolut Skin SPF 50 Moisturizing Sunscreen HUMAN OTC DRUG LABEL 4 84066-105 CREAM 2.50 mg TOPICAL OTC Monograph Drug 10 sections
XUEYI SKIN CARE SUNSCREEN HUMAN OTC DRUG LABEL 8 84753-037 CREAM 0.75 mg TOPICAL OTC Monograph Drug 7 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 84755-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 84755-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections
Centella Sunscreen SPF 50 HUMAN OTC DRUG LABEL 5 85473-442 CREAM 1.50 g CUTANEOUS OTC Monograph Drug 7 sections
Calming Days Vegan Sunscreen HUMAN OTC DRUG LABEL 4 85940-307 GEL 2 g TOPICAL OTC Monograph Drug 10 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 87565-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections