bencyclane indications/contra

Stem definitionDrug idCAS RN
301 2179-37-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bencyclane
  • benzcyclan
  • benzcyclane
  • bencyclane fumarate
A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
  • Molecular weight: 289.46
  • Formula: C19H31NO
  • CLOGP: 5.18
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 0
  • TPSA: 12.47
  • ALOGS: -5.90
  • ROTB: 7

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC C04AX11 CARDIOVASCULAR SYSTEM
PERIPHERAL VASODILATORS
PERIPHERAL VASODILATORS
Other peripheral vasodilators
MeSH PA D002121 Calcium Channel Blockers
MeSH PA D002317 Cardiovascular Agents
MeSH PA D049990 Membrane Transport Modulators
MeSH PA D014665 Vasodilator Agents

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Cerebrovascular disease indication 62914000 DOID:6713

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.39 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
N0000166387 NUI
C0004969 UMLSCUI
D07500 KEGG_DRUG
6I97Z6S135 UNII
2111 INN_ID
2312 PUBCHEM_CID
N0000166387 NDFRT
1367 RXNORM
007134 NDDF
CHEBI:135205 CHEBI
CHEMBL2105930 ChEMBL_ID
CHEMBL2110767 ChEMBL_ID
14286-84-1 SECONDARY_CAS_RN
D001537 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None