bamipine indications/contra

Stem definitionDrug idCAS RN
tricyclic compounds 288 4945-47-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • piperamine
  • bamipine dihydrochloride
  • bamipine lactate
  • bamipine monohydrochloride
  • bamipine citrate
  • bamipine dihydrochloride hydrate
  • multifungin
  • bamipine
  • taumidrine
  • bamipin
  • Molecular weight: 280.42
  • Formula: C19H24N2
  • CLOGP: 4.13
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 0
  • TPSA: 6.48
  • ALOGS: -3.81
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.10 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC D04AA15 DERMATOLOGICALS
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
Antihistamines for topical use
ATC R06AX01 RESPIRATORY SYSTEM
ANTIHISTAMINES FOR SYSTEMIC USE
ANTIHISTAMINES FOR SYSTEMIC USE
Other antihistamines for systemic use
MeSH PA D018494 Histamine Agents
MeSH PA D006633 Histamine Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Urticaria indication 126485001

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.35 Basic
pKa2 5.65 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Histamine H1 receptor GPCR ANTAGONIST KEGG DRUG KEGG DRUG

External reference:

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IDSource
C0771814 UMLSCUI
D07197 KEGG_DRUG
6K8KNJ07D8 UNII
61670-09-5 SECONDARY_CAS_RN
72075 PUBCHEM_CID
18753 RXNORM
003726 NDDF
CHEBI:135165 CHEBI
CHEMBL520400 ChEMBL_ID
C029080 MESH_SUPPLEMENTAL_RECORD_UI
C020867 MESH_SUPPLEMENTAL_RECORD_UI
1285 INN_ID

Pharmaceutical products:

None