bamifylline indications/contra

Stem definitionDrug idCAS RN
N-methylated xanthine derivatives 287 2016-63-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bamifylline
  • bamiphylline
  • benzetamophylline
  • benzethamophylline
  • Molecular weight: 385.47
  • Formula: C20H27N5O3
  • CLOGP: 2.03
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 1
  • TPSA: 81.91
  • ALOGS: -2.33
  • ROTB: 8

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC R03DA08 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Xanthines
MeSH PA D000700 Analgesics
MeSH PA D018927 Anti-Asthmatic Agents
MeSH PA D001337 Autonomic Agents
MeSH PA D001993 Bronchodilator Agents
MeSH PA D002317 Cardiovascular Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D019141 Respiratory System Agents
MeSH PA D018689 Sensory System Agents
MeSH PA D014665 Vasodilator Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.41 Basic
pKa2 3.05 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

scroll-->
IDSource
C0052945 UMLSCUI
D07491 KEGG_DRUG
18752 RXNORM
005237 NDDF
717098001 SNOMEDCT_US
16229 PUBCHEM_CID
C006683 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2110760 ChEMBL_ID
ZTY15D026H UNII
1837 INN_ID
CHEBI:135605 CHEBI

Pharmaceutical products:

None