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zeranol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2860 | 26538-44-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A non-steroidal estrogen analog.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT2,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK2,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GRK3,GSK3B,ITK,JAK1,JAK2,KIT,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK7,MAPK9,MAPKAPK2,MARK4,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 | 61 | |||
| kinase-selectivity-class | AXL,GRK2,TTK | 3 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D004967 | Estrogens |
| MeSH PA | D004968 | Estrogens, Non-Steroidal |
| MeSH PA | D006728 | Hormones |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cattle | To increase rate of weight gain | Indication |
| Cattle | To improve feed efficiency | Indication |
| Sheep | To increase rate of weight gain | Indication |
| Sheep | To improve feed efficiency | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Ralgro Implants, Ralgro Magnum | Intervet Inc. | 1 |
| Ralgro L. A. | Intervet Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.81 | acidic |
| pKa2 | 11.35 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000166852 | NUI |
| D06362 | KEGG_DRUG |
| C0043465 | UMLSCUI |
| CHEBI:35064 | CHEBI |
| 27J | PDB_CHEM_ID |
| CHEMBL450613 | ChEMBL_ID |
| DB11478 | DRUGBANK_ID |
| D015029 | MESH_DESCRIPTOR_UI |
| 2999413 | PUBCHEM_CID |
| 2844 | INN_ID |
| 76LO2L2V39 | UNII |
| 1368476 | RXNORM |
| 126176008 | SNOMEDCT_US |
| 96340007 | SNOMEDCT_US |
| 76LO2L2V39 | INXIGHT DRUGS |
Pharmaceutical products:
None