viomycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 2830 32988-50-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • viomycin
  • celiomycin
  • florimycin
  • Tuberactinomycin B
  • Vinacetin A
  • viomycin sulfate
A strongly basic peptide, antibiotic complex from several strains of Streptomyces. It is allergenic and toxic to kidneys and the labyrinth. Viomycin is used in tuberculosis as several different salts and in combination with other agents.
  • Molecular weight: 685.70
  • Formula: C25H43N13O10
  • CLOGP: -7.12
  • LIPINSKI: 3
  • HAC: 23
  • HDO: 15
  • TPSA: 392.86
  • ALOGS: -2.47
  • ROTB: 10

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA PFIZER

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:33231 antitubercular agents
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000904 Antibiotics, Antitubercular
MeSH PA D000995 Antitubercular Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D011500 Protein Synthesis Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.53 acidic
pKa2 12.11 acidic
pKa3 12.74 acidic
pKa4 13.0 acidic
pKa5 13.35 acidic
pKa6 13.69 acidic
pKa7 13.92 acidic
pKa8 11.06 Basic
pKa9 10.06 Basic
pKa10 7.7 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02270 KEGG_DRUG
C0042697 UMLSCUI
CHEBI:15782 CHEBI
CHEMBL3085436 ChEMBL_ID
D014756 MESH_DESCRIPTOR_UI
DB06827 DRUGBANK_ID
283 INN_ID
37883-00-4 SECONDARY_CAS_RN
YVU35998K5 UNII
135398671 PUBCHEM_CID
002773 NDDF
002774 NDDF
19967004 SNOMEDCT_US
CHEMBL3989823 ChEMBL_ID

Pharmaceutical products:

None