tybamate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
tranquillizers, propanediol and pentanediol derivatives 2783 4268-36-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tybamate
  • tibamate
  • tibamax
  • tybatran
major descriptor (65-84); on-line search CARBAMATES (65-84); Index Medicus search TYBAMATE (65-84)
  • Molecular weight: 274.36
  • Formula: C13H26N2O4
  • CLOGP: 3.09
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 90.65
  • ALOGS: -2.90
  • ROTB: 11

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IKBKB,ITK,JAK1,JAK2,MAP2K6,MAP3K21,MAP3K7,MAPK12,MAPK7,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK 46
kinase-selectivity-class AXL,BRAF,CAMK2D,CDK9,EPHB4,GRK2,STK33,TEK 8
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D06260 KEGG_DRUG
C0175163 UMLSCUI
CHEBI:135133 CHEBI
CHEMBL2104816 ChEMBL_ID
C100147 MESH_SUPPLEMENTAL_RECORD_UI
20266 PUBCHEM_CID
1721 INN_ID
3875LLL8M8 UNII
62178 RXNORM
001446 NDDF
12525000 SNOMEDCT_US

Pharmaceutical products:

None