azosemide indications/contra

Stem definitionDrug idCAS RN
diuretics, furosemide derivatives 278 27589-33-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • azosemide
  • diurapid
  • azosemid
  • Molecular weight: 370.83
  • Formula: C12H11ClN6O2S2
  • CLOGP: 1.36
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 126.65
  • ALOGS: -3.59
  • ROTB: 5

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D004232 Diuretics
MeSH PA D045283 Natriuretic Agents
CHEBI has role CHEBI:77608 loop diuretic

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Congestive heart failure indication 42343007 DOID:6000

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.68 acidic
pKa2 10.12 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0052820 UMLSCUI
D01323 KEGG_DRUG
18651 RXNORM
007033 NDDF
2273 PUBCHEM_CID
CHEMBL1097235 ChEMBL_ID
C018222 MESH_SUPPLEMENTAL_RECORD_UI
DB08961 DRUGBANK_ID
MR40VT1L8Z UNII
3954 INN_ID
CHEBI:31248 CHEBI

Pharmaceutical products:

None