tretamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2739 | 51-18-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000477 | Alkylating Agents |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D018906 | Antineoplastic Agents, Alkylating |
| MeSH PA | D009676 | Noxae |
| CHEBI has role | CHEBI:67105 | insect sterilants |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Malignant tumor of ovary | indication | 363443007 | DOID:2394 |
| Mood swings | contraindication | 18963009 | |
| Ataxia | contraindication | 20262006 | |
| Leukopenia | contraindication | 84828003 | DOID:615 |
| Anemia | contraindication | 271737000 | DOID:2355 |
| Pregnancy, function | contraindication | 289908002 | |
| Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
| Peripheral nerve disease | contraindication | 302226006 | |
| Bone marrow depression | contraindication | 307762000 | |
| Vertigo | contraindication | 399153001 | |
| Breastfeeding (mother) | contraindication | 413712001 | |
| Unconscious | contraindication | 418107008 | |
| Severe Bone Marrow Depression | contraindication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.42 | Basic |
| pKa2 | 1.8 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| C0040975 | UMLSCUI |
| CHEBI:27919 | CHEBI |
| CHEMBL502384 | ChEMBL_ID |
| DB14031 | DRUGBANK_ID |
| 5799 | PUBCHEM_CID |
| 002636 | NDDF |
| 20887007 | SNOMEDCT_US |
| D014265 | MESH_DESCRIPTOR_UI |
| 329 | INN_ID |
| F7IY6HZG9D | UNII |
Pharmaceutical products:
None