azidocillin indications/contra

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 273 17243-38-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • azidocillin potasium
  • azidocillin sodium
  • azidocillin
  • azidobenzylpenicillin
antibiotic similir to ampicillin; minor descriptor (75-86); on line & INDEX MEDICUS search PENICILLIN G/AA (75-86); RN given refers to (2S-(2alpha,5alpha,6beta(S*))-isomer)
  • Molecular weight: 375.40
  • Formula: C16H17N5O4S
  • CLOGP: 2.60
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 2
  • TPSA: 116.14
  • ALOGS: -2.79
  • ROTB: 5

Drug dosage:

DoseUnitRoute
1.50 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC J01CE04 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Beta-lactamase sensitive penicillins

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Respiratory tract infection indication 275498002

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0052772 UMLSCUI
D07235 KEGG_DRUG
0XPT6W6670 UNII
35334-12-4 SECONDARY_CAS_RN
18609 RXNORM
006819 NDDF
15574941 PUBCHEM_CID
C100243 MESH_SUPPLEMENTAL_RECORD_UI
DB08795 DRUGBANK_ID
CHEMBL2105907 ChEMBL_ID
2458 INN_ID
CHEBI:51758 CHEBI

Pharmaceutical products:

None