azaribine indications/contra

Stem definitionDrug idCAS RN
ribofuranyl-derivatives of the "pyrazofurin" type 27 2169-64-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • azaribine
  • triazure
  • azaribin
  • triacetyl-6-azauridine
  • triacetyl azauridine
  • 6-azauridine triacetate
pyrimidine analogue; anti-metabolite used in psoriasis & mycosis fungoides
  • Molecular weight: 371.30
  • Formula: C14H17N3O9
  • CLOGP: 0.19
  • LIPINSKI: 1
  • HAC: 12
  • HDO: 1
  • TPSA: 149.90
  • ALOGS: -2.12
  • ROTB: 8

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D003879 Dermatologic Agents
CHEBI has role CHEBI:50748 antipsoriatic
CHEBI has role CHEBI:50266 prodrug

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.42 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D03029 KEGG_DRUG
7BVB29RCPR UNII
54-25-1 SECONDARY_CAS_RN
002651 NDDF
CHEMBL564201 ChEMBL_ID
16574 PUBCHEM_CID
CHEMBL515914 ChEMBL_ID
C100231 MESH_SUPPLEMENTAL_RECORD_UI
2502 INN_ID
CHEBI:88272 CHEBI

Pharmaceutical products:

None