tinoridine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2672 24237-54-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tinoridine hydrochloride
  • tienoridine
  • tienoridine hydrochloride
  • tinoridine
  • tinoridine HCl
  • tienoridine HCl
proposed anti-inflammatory agent; minor descriptor (75-86); on-line & INDEX MEDICUS seach PYRIDINES (75-86)
  • Molecular weight: 316.42
  • Formula: C17H20N2O2S
  • CLOGP: 4.28
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 55.56
  • ALOGS: -4.18
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Pain indication 22253000




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.52 Basic
pKa2 3.34 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Adenosine receptor A1 GPCR ANTAGONIST EC50 4.99 SCIENTIFIC LITERATURE

External reference:

IDSource
D01484 KEGG_DRUG
25913-34-2 SECONDARY_CAS_RN
C0076703 UMLSCUI
CHEBI:32228 CHEBI
CHEMBL592943 ChEMBL_ID
DB13001 DRUGBANK_ID
C100290 MESH_SUPPLEMENTAL_RECORD_UI
5480 PUBCHEM_CID
3079 INN_ID
C9Z9ICZ7YR UNII

Pharmaceutical products:

None