thiopropazate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2634 84-06-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • thiopropazate
  • perphenazine acetate
  • thiopropazat
minor descriptor (66-72); major descriptor (73-85); on-line search PHENOTHIAZINES (66-85); Index Medicus search PHENOTHIAZINES (66-72); THIOPROPAZATE (73-85); RN given refers to parent cpd
  • Molecular weight: 446.01
  • Formula: C23H28ClN3O2S
  • CLOGP: 4.91
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 36.02
  • ALOGS: -4.84
  • ROTB: 8

Drug dosage:

DoseUnitRoute
60 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05AB05 NERVOUS SYSTEM
PSYCHOLEPTICS
ANTIPSYCHOTICS
Phenothiazines with piperazine structure
CHEBI has role CHEBI:37930 phenothiazine antipsychotic drugs
CHEBI has role CHEBI:48561 dopaminergic antagonists

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.85 Basic
pKa2 3.85 Basic
pKa3 2.21 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D09216 KEGG_DRUG
C0076513 UMLSCUI
CHEBI:59119 CHEBI
CHEMBL1697851 ChEMBL_ID
DB13557 DRUGBANK_ID
C100194 MESH_SUPPLEMENTAL_RECORD_UI
742 INN_ID
0JFY081Q2X UNII
6762 PUBCHEM_CID
38133 RXNORM
001487 NDDF
74713003 SNOMEDCT_US

Pharmaceutical products:

None