talampicillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 2554 47747-56-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aseocillin
  • talampicillin
  • ampicillin phthalidyl ester
  • talampicillin hydrochloride
  • talampicillin HCl
An ester of AMPICILLIN which is readily hydrolyzed on absorption to release ampicillin. It is well absorbed from the gastrointestinal tract resulting in a greater bioavailability of ampicillin than can be achieved with equivalent doses of ampicillin.
  • Molecular weight: 481.52
  • Formula: C24H23N3O6S
  • CLOGP: 1.59
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 2
  • TPSA: 128.03
  • ALOGS: -4.05
  • ROTB: 6

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01CA15 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Penicillins with extended spectrum
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:50266 Prodrugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.17 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000166996 NUI
D02201 KEGG_DRUG
C0039266 UMLSCUI
CHEBI:9391 CHEBI
CHEMBL1619785 ChEMBL_ID
CHEMBL1411731 ChEMBL_ID
D013626 MESH_DESCRIPTOR_UI
DB13814 DRUGBANK_ID
12289 IUPHAR_LIGAND_ID
3607 INN_ID
39878-70-1 SECONDARY_CAS_RN
29OJI73DPC UNII
71447 PUBCHEM_CID
10322 RXNORM
004046 NDDF
004047 NDDF
323694008 SNOMEDCT_US
387546006 SNOMEDCT_US
96073006 SNOMEDCT_US

Pharmaceutical products:

None