sulfalene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anti-infectives, sulfonamides | 2517 | 152-47-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.10 | g | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01ED02 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE SULFONAMIDES AND TRIMETHOPRIM Long-acting sulfonamides |
| ATC | P01BF04 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS ANTIMALARIALS Artemisinin and derivatives, combinations |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000892 | Anti-Infective Agents, Urinary |
| MeSH PA | D000962 | Antimalarials |
| MeSH PA | D000977 | Antiparasitic Agents |
| MeSH PA | D000981 | Antiprotozoal Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 5.4 | acidic |
| pKa2 | 2.39 | Basic |
| pKa3 | 1.75 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Dihydropteroate synthase | Enzyme | INHIBITOR | CHEMBL | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000166861 | NUI |
| D01216 | KEGG_DRUG |
| C0038683 | UMLSCUI |
| CHEBI:32162 | CHEBI |
| CHEMBL1525826 | ChEMBL_ID |
| D013415 | MESH_DESCRIPTOR_UI |
| DB00664 | DRUGBANK_ID |
| 10174 | IUPHAR_LIGAND_ID |
| 1209 | INN_ID |
| T6BL4ZC15G | UNII |
| 9047 | PUBCHEM_CID |
| 10175 | RXNORM |
| 004041 | NDDF |
| 324407006 | SNOMEDCT_US |
| 395890008 | SNOMEDCT_US |
Pharmaceutical products:
None