sulfaguanidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anti-infectives, sulfonamides | 2505 | 57-67-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A sulfanilamide antimicrobial agent that is used to treat enteric infections.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 4 | g | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Pulmonary pain | 211.07 | 137.78 | 35 | 535 | 4438 | 79739380 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A07AB03 | ALIMENTARY TRACT AND METABOLISM ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS INTESTINAL ANTIINFECTIVES Sulfonamides |
| MeSH PA | D000890 | Anti-Infective Agents |
| CHEBI has role | CHEBI:35441 | antiinfective agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.59 | acidic |
| pKa2 | 2.65 | Basic |
| pKa3 | 0.25 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Prothrombin | Enzyme | Ki | 7.02 | CHEMBL | |||||
| Trypsin | Enzyme | Ki | 5.87 | CHEMBL | |||||
| Protein argonaute-2 | Unclassified | Kd | 4.31 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000166871 | NUI |
| D02437 | KEGG_DRUG |
| C0038681 | UMLSCUI |
| CHEBI:94621 | CHEBI |
| QA9 | PDB_CHEM_ID |
| CHEMBL338802 | ChEMBL_ID |
| DB13726 | DRUGBANK_ID |
| D013414 | MESH_DESCRIPTOR_UI |
| 5324 | PUBCHEM_CID |
| 12639 | IUPHAR_LIGAND_ID |
| 423 | INN_ID |
| 15XQ8043FN | UNII |
| 10174 | RXNORM |
| 002839 | NDDF |
| 387500006 | SNOMEDCT_US |
| 86939001 | SNOMEDCT_US |
Pharmaceutical products:
None