sulfadimethoxine indications/contra

Stem definitionDrug idCAS RN
anti-infectives, sulfonamides 2501 122-11-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • sulfadimethoxine
  • neostreptal
  • suldixine
  • sulfabon
  • sulfadimethoxin
  • sulfadimethoxydiazin
  • sulfadimetoxin
  • sulfadimetoxine
  • sulfadimoxine
A sulfanilamide that is used as an anti-infective agent.
  • Molecular weight: 310.33
  • Formula: C12H14N4O4S
  • CLOGP: 1.98
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 116.43
  • ALOGS: -3.05
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.50 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC J01ED01 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
SULFONAMIDES AND TRIMETHOPRIM
Long-acting sulfonamides
CHEBI has role CHEBI:35441 antiinfective agent
MeSH PA D000890 Anti-Infective Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.93 acidic
pKa2 1.99 Basic
pKa3 0.4 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

scroll-->
TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
5-hydroxytryptamine receptor 6 GPCR Ki 6.21 DRUG MATRIX

External reference:

scroll-->
IDSource
N0000166864 NUI
C0038676 UMLSCUI
D01142 KEGG_DRUG
30CPC5LDEX UNII
840 INN_ID
CHEMBL62193 ChEMBL_ID
N0000166864 NDFRT
10172 RXNORM
387279005 SNOMEDCT_US
51013009 SNOMEDCT_US
002825 NDDF
5323 PUBCHEM_CID
DB06150 DRUGBANK_ID
D013412 MESH_DESCRIPTOR_UI
CHEBI:32161 CHEBI

Pharmaceutical products:

None