astromicin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
aminoglycosides, antibiotics obtained from various Micromonospora 250 55779-06-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • astromicin sulfate
  • astromicin
  • fortimicin a
  • Antibiotic KW 1070
  • Molecular weight: 405.50
  • Formula: C17H35N5O6
  • CLOGP: -1.23
  • LIPINSKI: 2
  • HAC: 11
  • HDO: 6
  • TPSA: 192.54
  • ALOGS: -1.27
  • ROTB: 6

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 0.23 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 1.37 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 2 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:25212 metabolites
CHEBI has role CHEBI:33282 bactericides

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.43 acidic
pKa2 8.99 Basic
pKa3 8.39 Basic
pKa4 7.52 Basic
pKa5 6.39 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01881 KEGG_DRUG
72275-67-3 SECONDARY_CAS_RN
C0060685 UMLSCUI
CHEBI:37923 CHEBI
CHEMBL3084803 ChEMBL_ID
CHEMBL3989466 ChEMBL_ID
C023384 MESH_SUPPLEMENTAL_RECORD_UI
5284517 PUBCHEM_CID
4904 INN_ID
7JHD84H15J UNII

Pharmaceutical products:

None