aspoxicillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 248 63358-49-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aspoxicillin
  • Molecular weight: 493.54
  • Formula: C21H27N5O7S
  • CLOGP: -3.20
  • LIPINSKI: 2
  • HAC: 12
  • HDO: 6
  • TPSA: 191.16
  • ALOGS: -2.98
  • ROTB: 8

Drug dosage:

DoseUnitRoute
4 g P

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 0.27 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 2.82 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 1.45 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01CA19 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Penicillins with extended spectrum

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic
pKa2 7.93 acidic
pKa3 11.71 acidic
pKa4 12.25 acidic
pKa5 7.09 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07469 KEGG_DRUG
C0104449 UMLSCUI
CHEBI:31240 CHEBI
CHEMBL1318150 ChEMBL_ID
DB13816 DRUGBANK_ID
C037485 MESH_SUPPLEMENTAL_RECORD_UI
12293 IUPHAR_LIGAND_ID
5350 INN_ID
0745KNO26J UNII
71961 PUBCHEM_CID

Pharmaceutical products:

None