sobuzoxane 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
benzodioxane derivatives 2455 98631-95-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • sobuzoxane
  • MST-16
  • perazolin
used in treatment of leukemia L1210
  • Molecular weight: 514.53
  • Formula: C22H34N4O10
  • CLOGP: 2.87
  • LIPINSKI: 2
  • HAC: 14
  • HDO: 0
  • TPSA: 152.30
  • ALOGS: -2.88
  • ROTB: 15

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000970 Antineoplastic Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D059005 Topoisomerase II Inhibitors
MeSH PA D059003 Topoisomerase Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.35 Basic
pKa2 1.0 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01404 KEGG_DRUG
C0378253 UMLSCUI
CHEBI:32136 CHEBI
CHEMBL1256871 ChEMBL_ID
C057773 MESH_SUPPLEMENTAL_RECORD_UI
C000283 MESH_SUPPLEMENTAL_RECORD_UI
6551 INN_ID
R1308VH37P UNII
5233 PUBCHEM_CID
C0600773 UMLSCUI
72760 PUBCHEM_CID

Pharmaceutical products:

None