arotinolol indications/contra

Stem definitionDrug idCAS RN
beta-adrenoreceptor antagonists 243 68377-92-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • arotinolol
  • arotinolol hydrochloride
  • arotinolol HCl
  • Molecular weight: 371.53
  • Formula: C15H21N3O2S3
  • CLOGP: 2.08
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 88.24
  • ALOGS: -4.22
  • ROTB: 8

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D018663 Adrenergic Agents
MeSH PA D000317 Adrenergic alpha-Antagonists
MeSH PA D018674 Adrenergic Antagonists
MeSH PA D000319 Adrenergic beta-Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.81 acidic
pKa2 9.91 Basic
pKa3 1.09 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D07465 KEGG_DRUG
394E3P3B99 UNII
5215 INN_ID
008153 NDDF
68377-91-3 SECONDARY_CAS_RN
CHEMBL93298 ChEMBL_ID
2239 PUBCHEM_CID
C024523 MESH_SUPPLEMENTAL_RECORD_UI
DB09204 DRUGBANK_ID
CHEBI:135569 CHEBI

Pharmaceutical products:

None