rufloxacin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 2412 101363-10-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • rufloxacin hydrochloride
  • rufloxacin hydrobromide
  • MF-934
  • rufloxacin
  • Molecular weight: 363.41
  • Formula: C17H18FN3O3S
  • CLOGP: -0.03
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 64.09
  • ALOGS: -2.58
  • ROTB: 2

Drug dosage:

DoseUnitRoute
0.20 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01MA10 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Fluoroquinolones
MeSH PA D000970 Antineoplastic Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D059005 Topoisomerase II Inhibitors
MeSH PA D059003 Topoisomerase Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.53 acidic
pKa2 8.29 Basic
pKa3 1.12 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02474 KEGG_DRUG
106017-08-7 SECONDARY_CAS_RN
C0073704 UMLSCUI
CHEBI:8909 CHEBI
CHEMBL295619 ChEMBL_ID
DB13772 DRUGBANK_ID
C060328 MESH_SUPPLEMENTAL_RECORD_UI
58258 PUBCHEM_CID
12473 IUPHAR_LIGAND_ID
6080 INN_ID
Y521XM2900 UNII
008179 NDDF
008180 NDDF
717102009 SNOMEDCT_US
717103004 SNOMEDCT_US

Pharmaceutical products:

None