arbekacin indications/contra

Stem definitionDrug idCAS RN
antibiotics, kanamycin and bekanamycin derivatives (obtained from Streptomyces kanamyceticus) 235 51025-85-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • arbekacin
  • AHB-DKB
  • HABA-DKB
  • habekacin
  • Molecular weight: 552.63
  • Formula: C22H44N6O10
  • CLOGP: -3.64
  • LIPINSKI: 3
  • HAC: 16
  • HDO: 11
  • TPSA: 297.27
  • ALOGS: -1.13
  • ROTB: 10

Drug dosage:

DoseUnitRoute
0.20 g P

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC J01GB12 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
AMINOGLYCOSIDE ANTIBACTERIALS
Other aminoglycosides
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:36047 antibacterial drug

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.04 acidic
pKa2 12.98 acidic
pKa3 13.55 acidic
pKa4 13.58 acidic
pKa5 9.4 Basic
pKa6 8.7 Basic
pKa7 7.75 Basic
pKa8 7.15 Basic
pKa9 6.49 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0062073 UMLSCUI
7345 IUPHAR_LIGAND_ID
D07462 KEGG_DRUG
007488 NDDF
26397 RXNORM
725569009 SNOMEDCT_US
CHEMBL426926 ChEMBL_ID
68682 PUBCHEM_CID
DB06696 DRUGBANK_ID
G7V6SLI20L UNII
5914 INN_ID
C031986 MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:37922 CHEBI
84G PDB_CHEM_ID

Pharmaceutical products:

None