aranidipine indications/contra

Stem definitionDrug idCAS RN
calcium channel blockers, nifedipine derivatives 234 86780-90-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aranidipine
  • sapresta
  • Molecular weight: 388.38
  • Formula: C19H20N2O7
  • CLOGP: 2.56
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 1
  • TPSA: 124.84
  • ALOGS: -4.54
  • ROTB: 8

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Hypertensive disorder indication 38341003 DOID:10763

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.5 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Voltage-gated L-type calcium channel Ion channel BLOCKER DRUG LABEL KEGG DRUG

External reference:

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IDSource
D01562 KEGG_DRUG
4Y7UR6X2PO UNII
7071 INN_ID
2225 PUBCHEM_CID
C059427 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2104030 ChEMBL_ID
DB09229 DRUGBANK_ID
CHEBI:31232 CHEBI

Pharmaceutical products:

None