propentofylline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
N-methylated xanthine derivatives 2296 55242-55-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • propentofylline
  • propentophylline
  • Molecular weight: 306.37
  • Formula: C15H22N4O3
  • CLOGP: 1.17
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 0
  • TPSA: 75.51
  • ALOGS: -2.05
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N06BC02 NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Xanthine derivatives
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018696 Neuroprotective Agents
MeSH PA D020011 Protective Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.63 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Acetylcholinesterase Enzyme IC50 5.19 CHEMBL

External reference:

IDSource
D01630 KEGG_DRUG
C0072171 UMLSCUI
CHEBI:32061 CHEBI
POY PDB_CHEM_ID
CHEMBL1079905 ChEMBL_ID
DB06479 DRUGBANK_ID
C032114 MESH_SUPPLEMENTAL_RECORD_UI
4938 PUBCHEM_CID
5005 INN_ID
5RTA398U4H UNII
34644 RXNORM
008166 NDDF

Pharmaceutical products:

None