prednisolone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 2245 50-24-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prednisolone
  • prenolone
  • deltahydrocortisone
  • hydroretrocortin
  • hydroretrocortine
  • metacortandralone
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
  • Molecular weight: 360.45
  • Formula: C21H28O5
  • CLOGP: 1.42
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 94.83
  • ALOGS: -3.18
  • ROTB: 2
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
10 mg O
10 mg P

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 1 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 0.22 mg/mL Bocci G, Oprea TI, Benet LZ
EoM (Fraction excreted unchanged in urine) 16 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 9.24 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BA (Bioavailability) 82 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 0.86 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 2.90 mL/min/kg Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma) 0.25 % Lombardo F, Berellini G, Obach RS
t_half (Half-life) 3.40 hours Lombardo F, Berellini G, Obach RS

Approvals:

DateAgencyCompanyOrphan
June 21, 1955 FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pneumocystis jirovecii pneumonia 1305.56 9.56 810 241200 16104 63230908
Cytomegalovirus infection 1017.32 9.56 753 241257 20199 63226813
Fatigue 757.21 9.56 1400 240610 886628 62360384
Pain 633.60 9.56 1164 240846 739464 62507548
Sepsis 533.83 9.56 1534 240476 151589 63095423
Product dose omission issue 502.38 9.56 136 241874 234177 63012835
Interstitial lung disease 451.84 9.56 831 241179 61077 63185935
Lymphoproliferative disorder 432.16 9.56 221 241789 2969 63244043
Completed suicide 421.35 9.56 36 241974 145637 63101375
Haemophagocytic lymphohistiocytosis 384.12 9.56 321 241689 10306 63236706
Hepatic function abnormal 381.29 9.56 581 241429 36561 63210451
Bronchopulmonary aspergillosis 369.73 9.56 288 241722 8347 63238665
Epstein-Barr virus infection 367.69 9.56 279 241731 7771 63239241
Abdominal discomfort 358.77 9.56 417 241593 320468 62926544
Posterior reversible encephalopathy syndrome 356.11 9.56 383 241627 16962 63230050
Pancytopenia 304.15 9.56 936 241074 95997 63151015
Post transplant lymphoproliferative disorder 302.32 9.56 206 241804 4825 63242187
Diffuse large B-cell lymphoma 298.57 9.56 229 241781 6483 63240529
Varicella zoster virus infection 298.23 9.56 163 241847 2526 63244486
Multiple organ dysfunction syndrome 297.41 9.56 664 241346 56088 63190924
Product use in unapproved indication 297.27 9.56 1411 240599 177669 63069343
Disseminated intravascular coagulation 285.91 9.56 358 241652 18693 63228319
Thrombotic microangiopathy 282.31 9.56 269 241741 10292 63236720
Injection site pain 274.90 9.56 77 241933 129723 63117289
Renal impairment 272.38 9.56 848 241162 87507 63159505
Nocardiosis 267.98 9.56 137 241873 1839 63245173
Swelling 264.66 9.56 400 241610 274978 62972034
Glossodynia 259.98 9.56 182 241828 178694 63068318
Osteonecrosis 259.23 9.56 389 241621 24141 63222871
Transplant rejection 259.02 9.56 259 241751 10521 63236491
Septic shock 257.00 9.56 693 241317 65936 63181076
Pemphigus 255.27 9.56 196 241814 183530 63063482
Progressive multifocal leukoencephalopathy 255.06 9.56 280 241730 12691 63234321
Hepatitis B 245.63 9.56 163 241847 3649 63243363
Drug hypersensitivity 244.72 9.56 511 241499 310176 62936836
Pyrexia 240.69 9.56 2795 239215 467683 62779329
Epstein-Barr virus associated lymphoproliferative disorder 235.84 9.56 124 241886 1770 63245242
Arthropathy 235.41 9.56 331 241679 234461 63012551
Sinusitis 229.75 9.56 317 241693 226336 63020676
Pneumatosis intestinalis 228.85 9.56 132 241878 2281 63244731
Off label use 223.59 9.56 3708 238302 670754 62576258
Pulmonary tuberculosis 222.90 9.56 164 241846 4353 63242659
Joint swelling 218.17 9.56 589 241421 327077 62919935
Hand deformity 217.83 9.56 173 241837 159284 63087728
Polyomavirus-associated nephropathy 216.03 9.56 116 241894 1732 63245280
Respiratory failure 215.83 9.56 864 241146 100994 63146018
Cytomegalovirus viraemia 209.06 9.56 173 241837 5476 63241536
Headache 206.77 9.56 1490 240520 631751 62615261
Aspergillus infection 204.75 9.56 200 241810 7893 63239119
Cytomegalovirus colitis 204.53 9.56 122 241888 2250 63244762
Hepatitis E 204.23 9.56 103 241907 1341 63245671
Premature delivery 204.08 9.56 393 241617 29888 63217124
Alopecia 201.98 9.56 638 241372 336898 62910114
Kidney transplant rejection 201.64 9.56 151 241859 4120 63242892
Pain in extremity 197.34 9.56 628 241382 330858 62916154
Nausea 196.20 9.56 2200 239810 852271 62394741
Leukopenia 192.14 9.56 690 241320 76600 63170412
Drug intolerance 192.07 9.56 573 241437 308088 62938924
Osteonecrosis of jaw 189.67 9.56 416 241594 34707 63212305
Death 188.52 9.56 761 241249 373620 62873392
Contraindicated product administered 186.84 9.56 340 241670 217308 63029704
Alveolar proteinosis 178.61 9.56 63 241947 302 63246710
Atypical femur fracture 177.23 9.56 154 241856 5218 63241794
Hepatitis B reactivation 175.67 9.56 123 241887 3014 63243998
Blood lactate dehydrogenase increased 173.24 9.56 314 241696 22802 63224210
BK virus infection 170.77 9.56 123 241887 3156 63243856
Disseminated tuberculosis 168.97 9.56 116 241894 2751 63244261
JC virus infection 167.83 9.56 102 241908 1949 63245063
Hypogammaglobulinaemia 166.57 9.56 169 241841 6986 63240026
Liver disorder 161.45 9.56 511 241499 53176 63193836
Cushingoid 161.37 9.56 180 241830 8305 63238707
Anxiety 159.47 9.56 372 241638 217169 63029843
Synovitis 158.62 9.56 294 241716 186624 63060388
Asthenia 157.41 9.56 840 241170 382764 62864248
Strongyloidiasis 156.23 9.56 82 241928 1166 63245846
Peripheral swelling 155.97 9.56 507 241503 265435 62981577
Febrile neutropenia 152.50 9.56 870 241140 117579 63129433
Pneumomediastinum 150.88 9.56 84 241926 1352 63245660
Steroid diabetes 149.81 9.56 81 241929 1227 63245785
Escherichia infection 148.87 9.56 212 241798 12542 63234470
Pneumocystis jirovecii infection 145.61 9.56 83 241927 1401 63245611
Toxicity to various agents 145.23 9.56 471 241539 246779 63000233
Peritonitis 142.76 9.56 244 241766 16910 63230102
Nasopharyngitis 142.74 9.56 494 241516 253763 62993249
Upper respiratory tract inflammation 141.46 9.56 99 241911 2424 63244588
Pneumonia bacterial 140.63 9.56 177 241833 9288 63237724
General physical health deterioration 140.55 9.56 1276 240734 200126 63046886
Discomfort 138.71 9.56 267 241743 167107 63079905
Cytomegalovirus test positive 138.70 9.56 105 241905 2913 63244099
Arthralgia 137.86 9.56 1448 240562 568262 62678750
Systemic lupus erythematosus 137.80 9.56 377 241633 208541 63038471
Overdose 132.22 9.56 146 241864 114932 63132080
Therapeutic product effect decreased 130.89 9.56 344 241666 192843 63054169
Dizziness 130.30 9.56 1032 240978 428893 62818119
Meningitis cryptococcal 129.72 9.56 75 241935 1302 63245710
Hypersensitivity 129.59 9.56 624 241386 292061 62954951
Feeling abnormal 128.91 9.56 230 241780 148162 63098850
Organising pneumonia 128.25 9.56 133 241877 5643 63241369
Chorioretinopathy 127.98 9.56 63 241947 776 63246236
Intentional overdose 126.70 9.56 62 241948 74090 63172922
Infection reactivation 125.60 9.56 70 241940 1129 63245883
Brain abscess 125.54 9.56 86 241924 2032 63244980
Muscle spasms 124.30 9.56 255 241755 155895 63091117
Disease recurrence 123.96 9.56 307 241703 27723 63219289
Mycobacterium chelonae infection 123.94 9.56 53 241957 459 63246553
Pneumonia cytomegaloviral 122.10 9.56 86 241924 2128 63244884
Weight increased 120.14 9.56 548 241462 260244 62986768
Enterocolitis 120.02 9.56 149 241861 7709 63239303
Pneumonia 119.84 9.56 2423 239587 454344 62792668
Weight decreased 119.14 9.56 596 241414 276202 62970810
Mucormycosis 119.11 9.56 94 241916 2777 63244235
Arthritis bacterial 117.61 9.56 134 241876 6329 63240683
Drug abuse 117.43 9.56 65 241945 72453 63174559
Wound 116.56 9.56 283 241727 162980 63084032
Tuberculosis 115.90 9.56 176 241834 11035 63235977
Pruritus 115.89 9.56 854 241156 360599 62886413
Herpes zoster 114.32 9.56 618 241392 81844 63165168
Fall 113.69 9.56 953 241057 391381 62855631
Hypotension 113.34 9.56 594 241416 272010 62975002
Anti-cyclic citrullinated peptide antibody positive 112.25 9.56 168 241842 116044 63130968
Bone marrow failure 112.23 9.56 304 241706 28986 63218026
Depression 112.11 9.56 379 241631 196113 63050899
Hospitalisation 111.56 9.56 96 241914 84985 63162027
Cerebral infarction 111.31 9.56 267 241743 23626 63223386
Therapy partial responder 111.14 9.56 168 241842 10490 63236522
Pleurisy 109.91 9.56 147 241863 8193 63238819
Gamma-glutamyltransferase increased 109.80 9.56 332 241678 33699 63213313
Wrong technique in product usage process 109.77 9.56 50 241960 62290 63184722
Immunosuppressant drug level increased 109.47 9.56 99 241911 3539 63243473
Polyomavirus viraemia 108.65 9.56 54 241956 680 63246332
Platelet count decreased 107.63 9.56 785 241225 115337 63131675
Insomnia 106.62 9.56 440 241570 214812 63032200
Injection site erythema 105.27 9.56 97 241913 83077 63163935
Pneumonia cryptococcal 104.44 9.56 54 241956 743 63246269
Cytomegalovirus infection reactivation 104.13 9.56 100 241910 3863 63243149
Oesophageal candidiasis 104.04 9.56 118 241892 5545 63241467
Premature baby 103.45 9.56 238 241772 20497 63226515
Adult T-cell lymphoma/leukaemia 103.15 9.56 37 241973 188 63246824
Lupus nephritis 103.09 9.56 86 241924 2753 63244259
Injection site reaction 102.95 9.56 47 241963 58477 63188535
Agranulocytosis 102.52 9.56 267 241743 24867 63222145
Complications of transplanted kidney 102.29 9.56 81 241929 2405 63244607
Staphylococcal sepsis 102.16 9.56 140 241870 7988 63239024
Exposure during pregnancy 100.68 9.56 970 241040 154577 63092435
Nasal congestion 100.45 9.56 63 241947 65597 63181415
Nephrotic syndrome 100.43 9.56 115 241895 5461 63241551
Acute respiratory distress syndrome 100.12 9.56 254 241756 23280 63223732
Alanine aminotransferase increased 99.34 9.56 707 241303 103063 63143949
Pseudomonas infection 99.30 9.56 164 241846 11049 63235963
Haemolytic anaemia 99.12 9.56 155 241855 9970 63237042
Blood pressure increased 99.12 9.56 303 241707 161759 63085253
Central nervous system lymphoma 98.65 9.56 65 241945 1437 63245575
Low birth weight baby 97.56 9.56 128 241882 7001 63240011
Epstein Barr virus positive mucocutaneous ulcer 97.52 9.56 43 241967 404 63246608
Scleroderma renal crisis 95.07 9.56 39 241971 301 63246711
Psoriasis 94.83 9.56 115 241895 86842 63160170
Rebound effect 94.75 9.56 101 241909 4425 63242587
Vasculitis 94.16 9.56 212 241798 17997 63229015
Stress 94.04 9.56 71 241939 67096 63179916
C-reactive protein increased 94.02 9.56 651 241359 94056 63152956
Viraemia 93.92 9.56 60 241950 1256 63245756
Pulmonary nocardiosis 93.23 9.56 39 241971 318 63246694
Thrombocytopenia 92.65 9.56 932 241078 150225 63096787
Aspartate aminotransferase increased 92.26 9.56 625 241385 89652 63157360
Lymphopenia 92.13 9.56 211 241799 18116 63228896
Herpes simplex 91.44 9.56 134 241876 8137 63238875
Hepatic enzyme increased 90.86 9.56 429 241581 201899 63045113
Musculoskeletal stiffness 90.40 9.56 379 241631 184239 63062773
Toxic epidermal necrolysis 90.20 9.56 256 241754 25078 63221934
Gastroenteritis 90.14 9.56 264 241746 26326 63220686
Sedation 89.97 9.56 19 241991 38790 63208222
Gait disturbance 87.26 9.56 380 241630 182798 63064214
Proteinuria 87.10 9.56 212 241798 18933 63228079
Inappropriate schedule of product administration 86.83 9.56 165 241845 103800 63143212
Liver transplant rejection 86.79 9.56 59 241951 1376 63245636
Renal phospholipidosis 86.61 9.56 27 241983 80 63246932
Injection site bruising 86.59 9.56 26 241984 41884 63205128
Balance disorder 86.51 9.56 117 241893 84305 63162707
Cerebral toxoplasmosis 86.15 9.56 51 241959 927 63246085
Confusional state 85.87 9.56 538 241472 235842 63011170
Diffuse large B-cell lymphoma recurrent 85.74 9.56 71 241939 2249 63244763
Gestational diabetes 85.65 9.56 131 241879 8265 63238747
Back pain 84.62 9.56 624 241386 263521 62983491
Cardiac failure 84.54 9.56 606 241404 88536 63158476
Migraine 83.73 9.56 167 241843 103179 63143833
COVID-19 83.66 9.56 726 241284 112377 63134635
Angiocentric lymphoma 83.40 9.56 43 241967 588 63246424
Cytomegalovirus enterocolitis 83.13 9.56 44 241966 637 63246375
Drug eruption 82.51 9.56 269 241741 28425 63218587
Cytomegalovirus chorioretinitis 81.56 9.56 62 241948 1731 63245281
Listeriosis 81.38 9.56 58 241952 1463 63245549
Eosinophilic granulomatosis with polyangiitis 80.84 9.56 67 241943 2125 63244887
Lymphoma 80.67 9.56 157 241853 12030 63234982
Atypical mycobacterial infection 80.62 9.56 51 241959 1049 63245963
Large intestine perforation 80.48 9.56 128 241882 8354 63238658
Substance-induced psychotic disorder 79.05 9.56 63 241947 1888 63245124
Bacteraemia 77.75 9.56 191 241819 17157 63229855
Myopathy 77.55 9.56 147 241863 11044 63235968
Blood pressure fluctuation 77.20 9.56 40 241970 46277 63200735
Cytomegalovirus enteritis 76.70 9.56 32 241978 259 63246753
Pleural effusion 76.22 9.56 612 241398 92598 63154414
Symptom masked 75.95 9.56 43 241967 716 63246296
Pyelonephritis 75.75 9.56 192 241818 17586 63229426
Adrenal suppression 75.73 9.56 46 241964 878 63246134
Klebsiella infection 75.47 9.56 125 241885 8441 63238571
Drug ineffective for unapproved indication 75.36 9.56 293 241717 33770 63213242
Hypofibrinogenaemia 75.31 9.56 50 241960 1120 63245892
Infusion related reaction 74.85 9.56 588 241422 244933 63002079
Infectious pleural effusion 74.80 9.56 56 241954 1527 63245485
Constipation 74.15 9.56 527 241483 224416 63022596
Parvovirus B19 infection 73.68 9.56 38 241972 520 63246492
Injection site pruritus 73.67 9.56 40 241970 45076 63201936
Spinal compression fracture 73.53 9.56 166 241844 14117 63232895
Encephalitis 73.48 9.56 126 241884 8754 63238258
Cryptococcosis 73.40 9.56 49 241961 1108 63245904
Irritable bowel syndrome 73.11 9.56 126 241884 82286 63164726
Contusion 72.22 9.56 310 241700 149734 63097278
Hyperglycaemia 71.59 9.56 333 241677 41534 63205478
Injection site swelling 70.91 9.56 47 241963 47525 63199487
Mental status changes 70.90 9.56 31 241979 39568 63207444
Immunosuppression 70.24 9.56 123 241887 8691 63238321
Diabetes mellitus 69.86 9.56 407 241603 55403 63191609
Unevaluable event 69.80 9.56 56 241954 51330 63195682
Pericarditis 69.54 9.56 262 241748 131317 63115695
Product use issue 69.15 9.56 524 241486 219996 63027016
Cerebrovascular accident 68.89 9.56 198 241812 107826 63139186
Urosepsis 68.71 9.56 190 241820 18334 63228678
Mycobacterium marinum infection 68.64 9.56 29 241981 243 63246769
Illness 68.49 9.56 52 241958 49007 63198005
Neutropenic sepsis 68.45 9.56 176 241834 16262 63230750
Therapy cessation 68.41 9.56 16 241994 30441 63216571
Diarrhoea 68.23 9.56 2143 239867 713223 62533789
Chronic graft versus host disease 68.10 9.56 71 241939 3031 63243981
Osteoporosis 67.83 9.56 412 241598 56926 63190086
Heart rate increased 67.50 9.56 163 241847 94075 63152937
Mycobacterium abscessus infection 67.47 9.56 38 241972 626 63246386
Disseminated cryptococcosis 67.36 9.56 33 241977 402 63246610
Enterococcal infection 67.11 9.56 113 241897 7735 63239277
Multiple sclerosis relapse 66.89 9.56 52 241958 48426 63198586
Blood beta-D-glucan increased 66.76 9.56 27 241983 200 63246812
Electrocardiogram QT prolonged 66.75 9.56 77 241933 59453 63187559
Adrenal insufficiency 66.70 9.56 184 241826 17731 63229281
Steroid withdrawal syndrome 65.93 9.56 35 241975 510 63246502
Cardiac failure congestive 65.32 9.56 161 241849 92272 63154740
Blood pressure systolic increased 65.20 9.56 51 241959 47346 63199666
Neutropenia 65.00 9.56 982 241028 174023 63072989
Tuberculous pleurisy 64.80 9.56 32 241978 397 63246615
Mycobacterium avium complex infection 64.80 9.56 69 241941 3019 63243993
Mycobacterial infection 64.72 9.56 54 241956 1729 63245283
Staphylococcal infection 64.65 9.56 320 241690 40936 63206076
Subarachnoid haemorrhage 63.74 9.56 157 241853 14126 63232886
Pneumothorax 63.52 9.56 170 241840 16091 63230921
Drug resistance 63.26 9.56 212 241798 22721 63224291
Product quality issue 62.77 9.56 29 241981 35836 63211176
Gastrooesophageal reflux disease 62.68 9.56 173 241837 95466 63151546
Rhinorrhoea 62.15 9.56 96 241914 65481 63181531
Rheumatoid factor positive 62.04 9.56 144 241866 84262 63162750
Therapy interrupted 62.04 9.56 23 241987 32432 63214580
Hepatic failure 61.99 9.56 285 241725 35371 63211641
Suicide attempt 61.83 9.56 85 241925 60833 63186179
Tendon rupture 61.83 9.56 112 241898 8127 63238885
Gastric ulcer 61.75 9.56 217 241793 23820 63223192
Nephropathy toxic 61.39 9.56 121 241889 9358 63237654
Device dislocation 60.80 9.56 12 241998 25693 63221319
Incorrect dose administered 60.54 9.56 84 241926 59884 63187128
Bacterial sepsis 60.37 9.56 75 241935 3883 63243129
Myelodysplastic syndrome 59.35 9.56 169 241841 16585 63230427
Skin ulcer 59.22 9.56 322 241688 42723 63204289
Device issue 58.62 9.56 10 242000 23771 63223241
Premature labour 58.53 9.56 140 241870 12364 63234648
Foetal growth restriction 58.37 9.56 104 241906 7449 63239563
Subcutaneous emphysema 58.15 9.56 38 241972 828 63246184
Necrotising retinitis 57.13 9.56 29 241981 383 63246629
Liver abscess 56.78 9.56 62 241948 2792 63244220
Foetal exposure during pregnancy 56.70 9.56 257 241753 31705 63215307
Adenovirus infection 56.62 9.56 69 241941 3502 63243510
Splenic abscess 56.32 9.56 22 241988 147 63246865
Aplasia pure red cell 55.96 9.56 77 241933 4410 63242602
Phaeohyphomycosis 55.80 9.56 26 241984 281 63246731
Suicidal ideation 55.76 9.56 95 241915 62326 63184686
Serotonin syndrome 55.38 9.56 20 241990 28662 63218350
Pneumoperitoneum 55.09 9.56 45 241965 1398 63245614
Malignant neoplasm of conjunctiva 55.07 9.56 16 241994 34 63246978
Hypoalbuminaemia 55.07 9.56 132 241878 11673 63235339
Somnolence 54.40 9.56 428 241582 178257 63068755
Lymphocytic infiltration 54.05 9.56 37 241973 873 63246139
Osteoporotic fracture 53.98 9.56 69 241941 3677 63243335
Listeria sepsis 53.67 9.56 34 241976 701 63246311
Necrotising fasciitis 53.56 9.56 62 241948 2979 63244033
Enteritis infectious 52.81 9.56 52 241958 2072 63244940
Neck pain 52.78 9.56 116 241894 69202 63177810
Rash 52.45 9.56 1684 240326 559187 62687825
Lung infiltration 52.32 9.56 147 241863 14316 63232696
Normal newborn 52.25 9.56 105 241905 8236 63238776
Full blood count decreased 52.23 9.56 17 241993 26007 63221005
Immunosuppressant drug level decreased 52.16 9.56 37 241973 926 63246086
Graft versus host disease 52.11 9.56 93 241917 6670 63240342
Red blood cell sedimentation rate abnormal 51.78 9.56 7 242003 19775 63227237
Infection in an immunocompromised host 51.48 9.56 33 241977 695 63246317
Muscle abscess 51.32 9.56 26 241984 342 63246670
Heart rate decreased 51.00 9.56 59 241951 45501 63201511
Oral candidiasis 50.34 9.56 196 241814 22602 63224410
Ear infection 50.22 9.56 43 241967 38170 63208842
Altered state of consciousness 50.20 9.56 210 241800 25020 63221992
Pneumonitis 50.16 9.56 266 241744 34956 63212056
Placenta accreta 50.15 9.56 22 241988 204 63246808
Endocarditis 49.44 9.56 83 241927 5667 63241345
Iron deficiency anaemia 49.35 9.56 178 241832 19791 63227221
Sinus disorder 49.34 9.56 16 241994 24537 63222475
Full blood count abnormal 49.10 9.56 30 241980 31687 63215325
Cholangitis 48.79 9.56 81 241929 5480 63241532
Meningitis bacterial 48.79 9.56 41 241969 1326 63245686
Epstein-Barr virus infection reactivation 48.72 9.56 33 241977 765 63246247
Fluid retention 48.72 9.56 96 241914 59590 63187422
Burning sensation 48.41 9.56 83 241927 54324 63192688
Nervousness 48.38 9.56 29 241981 30950 63216062
Viral vasculitis 47.98 9.56 15 241995 45 63246967
Obliterative bronchiolitis 47.88 9.56 49 241961 2046 63244966
Endocarditis bacterial 47.64 9.56 30 241980 612 63246400
Muscle injury 47.60 9.56 112 241898 65233 63181779
Opportunistic infection 47.54 9.56 47 241963 1882 63245130
Angiosarcoma 47.44 9.56 22 241988 235 63246777
Systemic candida 47.12 9.56 60 241950 3185 63243827
Macular degeneration 47.06 9.56 17 241993 24359 63222653
Memory impairment 46.79 9.56 221 241789 104037 63142975
Acute graft versus host disease 46.46 9.56 70 241940 4358 63242654
Diffuse large B-cell lymphoma refractory 46.20 9.56 38 241972 1192 63245820
Intentional self-injury 46.16 9.56 20 241990 25667 63221345
Splenomegaly 45.99 9.56 119 241891 11038 63235974
Escherichia bacteraemia 45.99 9.56 65 241945 3818 63243194
Pancreatic steatosis 45.92 9.56 35 241975 981 63246031
Treatment failure 45.87 9.56 511 241499 198532 63048480
Bradycardia 45.39 9.56 136 241874 73091 63173921
Secondary adrenocortical insufficiency 45.23 9.56 40 241970 1388 63245624
Injection site haemorrhage 45.19 9.56 18 241992 24296 63222716
Accidental exposure to product 45.18 9.56 24 241986 27381 63219631
Cerebral haemorrhage 45.09 9.56 234 241776 30495 63216517
Ill-defined disorder 45.02 9.56 160 241850 81595 63165417
Systemic mycosis 45.01 9.56 37 241973 1160 63245852
Joint stiffness 44.97 9.56 56 241954 41813 63205199
Multiple-drug resistance 44.95 9.56 75 241935 5095 63241917
Pyoderma gangrenosum 44.90 9.56 62 241948 3563 63243449
Malacoplakia 44.79 9.56 19 241991 161 63246851
Secondary immunodeficiency 44.32 9.56 39 241971 1344 63245668
Haemolytic uraemic syndrome 44.03 9.56 51 241959 2452 63244560
Pyelonephritis acute 43.98 9.56 70 241940 4571 63242441
Disseminated trichosporonosis 43.93 9.56 15 241995 64 63246948
Herpes zoster meningitis 43.56 9.56 15 241995 66 63246946
Transplant failure 43.55 9.56 41 241969 1544 63245468
Emotional distress 43.54 9.56 36 241974 32513 63214499
Scedosporium infection 43.52 9.56 27 241983 536 63246476
Human T-cell lymphotropic virus type I infection 43.38 9.56 14 241996 48 63246964
Shock 43.38 9.56 191 241819 23272 63223740
Retinal detachment 43.35 9.56 80 241930 5889 63241123
Neuropsychiatric lupus 43.33 9.56 19 241991 176 63246836
Lung abscess 43.26 9.56 44 241966 1824 63245188
Subcutaneous abscess 43.18 9.56 77 241933 5519 63241493
Erysipelas 43.08 9.56 94 241916 7811 63239201
Cytomegalovirus hepatitis 42.85 9.56 23 241987 343 63246669
Premature rupture of membranes 42.84 9.56 72 241938 4921 63242091
Dyspepsia 42.78 9.56 222 241788 101974 63145038
Inflammatory marker increased 42.73 9.56 86 241924 6753 63240259
Acute graft versus host disease in skin 42.69 9.56 59 241951 3393 63243619
Lemierre syndrome 42.69 9.56 16 241994 94 63246918
Eczema herpeticum 42.59 9.56 18 241992 151 63246861
Systemic infection 42.40 9.56 69 241941 4591 63242421
Central obesity 42.30 9.56 36 241974 1185 63245827
Influenza like illness 42.22 9.56 123 241887 66701 63180311
Pancreatitis acute 42.05 9.56 210 241800 26956 63220056
Hot flush 42.00 9.56 82 241928 51077 63195935
Pulmonary embolism 41.85 9.56 651 241359 116033 63130979
Chronic allograft nephropathy 41.83 9.56 29 241981 699 63246313
Injection site mass 41.50 9.56 10 242000 18646 63228366
Maternal exposure during pregnancy 41.32 9.56 1115 240895 218947 63028065
Sedation complication 41.10 9.56 3 242007 13819 63233193
Duodenal ulcer 40.88 9.56 91 241919 7665 63239347
Interleukin-2 receptor increased 40.77 9.56 15 241995 83 63246929
Bone tuberculosis 40.72 9.56 19 241991 206 63246806
Paraesthesia 40.65 9.56 392 241618 156574 63090438
Tremor 40.58 9.56 316 241694 131923 63115089
Erythema multiforme 40.42 9.56 107 241903 10062 63236950
Ascites 40.41 9.56 280 241730 40448 63206564
Intraocular pressure increased 39.86 9.56 78 241932 6000 63241012
Escherichia urinary tract infection 39.81 9.56 118 241892 11844 63235168
Blood glucose decreased 39.79 9.56 15 241995 20937 63226075
Infusion site pain 39.64 9.56 8 242002 16861 63230151
Meningitis listeria 39.63 9.56 27 241983 632 63246380
Cardiac disorder 39.55 9.56 84 241926 50732 63196280
Heart rate irregular 39.44 9.56 18 241992 22403 63224609
Kaposi's sarcoma 39.38 9.56 17 241993 151 63246861
Atypical haemolytic uraemic syndrome 39.26 9.56 28 241982 707 63246305
Crying 39.14 9.56 20 241990 23323 63223689
Central nervous system vasculitis 39.07 9.56 31 241979 923 63246089
Jaundice 39.02 9.56 217 241793 29034 63217978
Circulatory collapse 38.61 9.56 176 241834 21762 63225250
Musculoskeletal chest pain 38.55 9.56 16 241994 21067 63225945
Ocular hypertension 38.53 9.56 32 241978 1018 63245994
Haemorrhage subcutaneous 38.43 9.56 52 241958 2931 63244081
Renal transplant failure 38.35 9.56 28 241982 734 63246278
Empyema 38.16 9.56 43 241967 2006 63245006
Neuropathy peripheral 38.05 9.56 265 241745 113402 63133610
Varicella zoster pneumonia 37.90 9.56 12 241998 38 63246974
Blood glucose increased 37.90 9.56 177 241833 83579 63163433
Immune thrombocytopenia 37.90 9.56 107 241903 10449 63236563
Loss of personal independence in daily activities 37.61 9.56 217 241793 97073 63149939
Trichophytosis 37.61 9.56 13 241997 58 63246954
Adrenal atrophy 37.36 9.56 11 241999 25 63246987
Anaemia 37.36 9.56 1419 240591 292011 62955001
Femoral neck fracture 37.31 9.56 93 241917 8430 63238582
Diverticular perforation 37.17 9.56 56 241954 3486 63243526
Arterial haemorrhage 37.16 9.56 39 241971 1678 63245334
White blood cell count increased 37.08 9.56 314 241696 48247 63198765
Leukoencephalopathy 37.02 9.56 63 241947 4350 63242662
Aortic dissection 36.99 9.56 42 241968 1976 63245036
Foetal methotrexate syndrome 36.99 9.56 15 241995 112 63246900
Feeling jittery 36.91 9.56 4 242006 13399 63233613
Procedural pain 36.88 9.56 18 241992 21551 63225461
Blood pressure systolic abnormal 36.85 9.56 4 242006 13382 63233630
Unresponsive to stimuli 36.56 9.56 45 241965 33771 63213241
Surgery 36.55 9.56 50 241960 35862 63211150
Dry eye 36.43 9.56 62 241948 40699 63206313
Drug interaction 36.43 9.56 1137 240873 227994 63019018
Intussusception 36.41 9.56 25 241985 593 63246419
Concomitant disease aggravated 36.34 9.56 96 241914 9016 63237996
Acute abdomen 36.33 9.56 37 241973 1536 63245476
Cystitis haemorrhagic 36.10 9.56 60 241950 4063 63242949
Visceral leishmaniasis 36.09 9.56 24 241986 539 63246473
Mycotic endophthalmitis 36.09 9.56 13 241997 67 63246945
Sinus congestion 36.08 9.56 12 241998 18111 63228901
Bronchiectasis 35.82 9.56 139 241871 16003 63231009
Bedridden 35.82 9.56 108 241902 10943 63236069
Antiphospholipid syndrome 35.81 9.56 39 241971 1751 63245261
Small intestinal perforation 35.66 9.56 36 241974 1479 63245533
Hypoaesthesia 35.06 9.56 442 241568 167951 63079061
Throat irritation 34.82 9.56 56 241954 37591 63209421
Neuroleptic malignant syndrome 34.77 9.56 3 242007 12053 63234959
Bacterial infection 34.74 9.56 157 241853 19342 63227670
Folliculitis 34.60 9.56 144 241866 70173 63176839
Hepatitis 34.58 9.56 265 241745 39523 63207489
Coombs positive haemolytic anaemia 34.40 9.56 20 241990 351 63246661
Limb reduction defect 34.38 9.56 21 241989 405 63246607
Transaminases increased 34.35 9.56 221 241789 31146 63215866
Synovectomy 34.25 9.56 16 241994 174 63246838
Disseminated varicella zoster virus infection 34.10 9.56 18 241992 259 63246753
Drug withdrawal syndrome 34.06 9.56 32 241978 27162 63219850
Tachyarrhythmia 34.04 9.56 61 241949 4389 63242623
Adrenocortical insufficiency acute 33.98 9.56 37 241973 1661 63245351
Melaena 33.90 9.56 215 241795 30150 63216862
Auditory neuropathy spectrum disorder 33.88 9.56 10 242000 23 63246989
Intentional product misuse 33.68 9.56 119 241891 60798 63186214
Cognitive disorder 33.63 9.56 105 241905 55710 63191302
Polyneuropathy 33.50 9.56 127 241883 14462 63232550
Colon cancer 33.40 9.56 98 241912 9780 63237232
Product monitoring error 33.39 9.56 61 241949 4455 63242557
Lymphadenopathy 33.34 9.56 256 241754 38202 63208810
Paroxysmal extreme pain disorder 33.26 9.56 13 241997 87 63246925
Injection site rash 33.24 9.56 15 241995 18794 63228218
Helicobacter infection 33.22 9.56 212 241798 92573 63154439
Cardiac valve vegetation 33.16 9.56 18 241992 275 63246737
Tubulointerstitial nephritis 33.06 9.56 157 241853 19746 63227266
Primary biliary cholangitis 32.92 9.56 31 241979 1168 63245844
Anogenital warts 32.90 9.56 22 241988 499 63246513
Ecthyma 32.87 9.56 18 241992 280 63246732
Arthritis 32.83 9.56 283 241727 115638 63131374
Lymph node tuberculosis 32.80 9.56 26 241984 773 63246239
Gastrointestinal disorder 32.61 9.56 331 241679 130908 63116104
Blood creatinine increased 32.61 9.56 493 241517 87351 63159661
Abscess 32.59 9.56 138 241872 16530 63230482
Restless legs syndrome 32.40 9.56 15 241995 18516 63228496
Graft versus host disease in gastrointestinal tract 32.26 9.56 50 241960 3191 63243821
Hepatitis viral 32.20 9.56 21 241989 456 63246556
Pneumonia fungal 32.19 9.56 67 241943 5388 63241624
Tumour lysis syndrome 32.15 9.56 91 241919 8899 63238113
Meningitis 32.14 9.56 79 241931 7098 63239914
Enterococcal sepsis 32.11 9.56 33 241977 1385 63245627
Panniculitis 32.07 9.56 106 241904 11279 63235733
Rheumatoid arthritis 32.00 9.56 730 241280 253089 62993923
Blood immunoglobulin G decreased 31.89 9.56 43 241967 2415 63244597
Heart transplant rejection 31.87 9.56 23 241987 592 63246420
Growth retardation 31.81 9.56 32 241978 1309 63245703
Graft loss 31.68 9.56 19 241991 354 63246658
Infective exacerbation of chronic obstructive airways disease 31.67 9.56 31 241979 1226 63245786
Encephalitis viral 31.67 9.56 36 241974 1696 63245316
Synostosis 31.66 9.56 11 241999 50 63246962
Sleep disorder due to general medical condition, insomnia type 31.63 9.56 98 241912 52119 63194893
Gastritis haemorrhagic 31.50 9.56 34 241976 1511 63245501
IIIrd nerve paralysis 31.45 9.56 24 241986 674 63246338
Neisseria infection 31.40 9.56 13 241997 103 63246909
Escherichia sepsis 31.32 9.56 63 241947 4944 63242068
Transplant dysfunction 31.32 9.56 62 241948 4810 63242202
Sleep apnoea syndrome 31.25 9.56 39 241971 29094 63217918
Poisoning 31.16 9.56 7 242003 13693 63233319
Thyroiditis subacute 31.07 9.56 17 241993 264 63246748
Tonsillitis 31.03 9.56 68 241942 5667 63241345
Anaphylactoid reaction 31.03 9.56 53 241957 3670 63243342
Intervertebral discitis 31.02 9.56 49 241961 3179 63243833
Hydronephrosis 30.69 9.56 100 241910 10562 63236450
Loss of consciousness 30.57 9.56 295 241715 117826 63129186
Nephrolithiasis 30.54 9.56 72 241938 41912 63205100
Hypopyon 30.44 9.56 24 241986 708 63246304
Injection site urticaria 30.43 9.56 8 242002 14065 63232947
Neonatal hypoacusis 30.41 9.56 9 242001 21 63246991
Injection site warmth 30.36 9.56 10 242000 15185 63231827
Meningitis tuberculous 30.32 9.56 22 241988 571 63246441
Central nervous system fungal infection 29.97 9.56 13 241997 117 63246895
B-cell lymphoma recurrent 29.90 9.56 19 241991 394 63246618
Talipes 29.85 9.56 33 241977 1507 63245505
Cytomegalovirus gastroenteritis 29.76 9.56 15 241995 195 63246817
Systemic inflammatory response syndrome 29.68 9.56 66 241944 5555 63241457
Seizure 29.56 9.56 343 241667 132291 63114721
Cutaneous nocardiosis 29.56 9.56 9 242001 24 63246988
Thymoma 29.56 9.56 15 241995 198 63246814
Lupus pancreatitis 29.53 9.56 7 242003 3 63247009
Dysgeusia 29.48 9.56 86 241924 46624 63200388
Anuria 29.43 9.56 110 241900 12441 63234571
Stevens-Johnson syndrome 29.32 9.56 179 241831 24771 63222241
Colitis ulcerative 29.29 9.56 185 241825 25906 63221106
Degenerative bone disease 29.28 9.56 14 241996 161 63246851
Lower limb fracture 29.25 9.56 175 241835 24046 63222966
Humoral immune defect 29.21 9.56 16 241994 249 63246763
Tooth infection 29.09 9.56 16 241994 17904 63229108
Dehydration 29.06 9.56 475 241535 172879 63074133
Alveolitis 29.06 9.56 45 241965 2870 63244142
Gallbladder disorder 28.92 9.56 18 241992 18824 63228188
Osteomyelitis 28.90 9.56 184 241826 25836 63221176
Herpes simplex reactivation 28.88 9.56 21 241989 547 63246465
Substance-induced mood disorder 28.87 9.56 7 242003 4 63247008
Tooth disorder 28.86 9.56 39 241971 28118 63218894
Psoas abscess 28.81 9.56 20 241990 483 63246529
Flushing 28.74 9.56 168 241842 74919 63172093
Retinitis viral 28.68 9.56 10 242000 46 63246966
Gallbladder rupture 28.52 9.56 19 241991 428 63246584
Gastric ulcer perforation 28.41 9.56 29 241981 1207 63245805
Passenger lymphocyte syndrome 28.35 9.56 11 241999 72 63246940
Dry skin 28.30 9.56 116 241894 56771 63190241
Joint injury 28.29 9.56 43 241967 29529 63217483
Herpes simplex viraemia 28.24 9.56 17 241993 319 63246693
Paraneoplastic pemphigus 28.22 9.56 11 241999 73 63246939
Lumbar vertebral fracture 28.22 9.56 66 241944 5744 63241268
Chronic respiratory disease 28.19 9.56 14 241996 176 63246836
Blood pressure diastolic decreased 28.11 9.56 27 241983 22679 63224333
Gastroenteritis clostridial 28.10 9.56 21 241989 571 63246441
Hypersomnia 28.06 9.56 17 241993 18038 63228974
Dermatophytosis 28.05 9.56 14 241996 178 63246834
Psoriatic arthropathy 27.93 9.56 219 241791 91301 63155711
Infection masked 27.86 9.56 9 242001 31 63246981
Diverticulum intestinal haemorrhagic 27.79 9.56 32 241978 1529 63245483
Pneumonia haemophilus 27.79 9.56 22 241988 653 63246359
Type 1 diabetes mellitus 27.78 9.56 51 241959 3739 63243273
T-cell lymphoma 27.76 9.56 22 241988 654 63246358
Cutaneous tuberculosis 27.54 9.56 13 241997 145 63246867
Microsporidia infection 27.51 9.56 16 241994 281 63246731
Pre-eclampsia 27.50 9.56 87 241923 9046 63237966
Respiratory tract congestion 27.42 9.56 17 241993 17815 63229197
Oligohydramnios 27.38 9.56 69 241941 6297 63240715
Symblepharon 27.37 9.56 11 241999 80 63246932
Gastritis 27.32 9.56 239 241771 37064 63209948
Jaw operation 27.25 9.56 24 241986 828 63246184
Human herpesvirus 6 infection 27.20 9.56 44 241966 2913 63244099
Rheumatoid vasculitis 27.16 9.56 17 241993 343 63246669
Anal prolapse 27.14 9.56 11 241999 82 63246930
Polyomavirus test positive 27.14 9.56 11 241999 82 63246930
Diverticulum intestinal 27.05 9.56 71 241939 6642 63240370
HIV infection 27.04 9.56 18 241992 405 63246607
Oxygen saturation decreased 27.02 9.56 212 241798 88373 63158639
Neuromyelitis optica spectrum disorder 26.99 9.56 26 241984 1008 63246004
Cloacal exstrophy 26.93 9.56 13 241997 153 63246859
Small for dates baby 26.90 9.56 50 241960 3701 63243311
Confusional arousal 26.86 9.56 14 241996 196 63246816
Laboratory test abnormal 26.86 9.56 38 241972 26874 63220138
Encephalitis cytomegalovirus 26.85 9.56 20 241990 541 63246471
Bursitis infective staphylococcal 26.81 9.56 9 242001 36 63246976
Bronchiolitis 26.81 9.56 42 241968 2705 63244307
Influenza 26.68 9.56 275 241735 108447 63138565
Wound infection pseudomonas 26.68 9.56 29 241981 1299 63245713
Carpal tunnel syndrome 26.66 9.56 24 241986 20793 63226219
Cytopenia 26.65 9.56 101 241909 11500 63235512
Listeria encephalitis 26.53 9.56 15 241995 249 63246763
Dyskinesia 26.52 9.56 51 241959 31951 63215061
Reversible cerebral vasoconstriction syndrome 26.45 9.56 41 241969 2617 63244395
Gastrointestinal amyloidosis 26.37 9.56 10 242000 61 63246951
Aortic valve stenosis 26.24 9.56 46 241964 3253 63243759
Immune reconstitution inflammatory syndrome 26.22 9.56 66 241944 6018 63240994
Lymphocele 26.10 9.56 23 241987 794 63246218
Purpura 26.05 9.56 99 241911 11286 63235726
Lymphocyte stimulation test positive 25.96 9.56 19 241991 500 63246512
Bronchopleural fistula 25.95 9.56 14 241996 211 63246801
Myelopathy 25.92 9.56 42 241968 2784 63244228
Sleep disorder 25.92 9.56 193 241817 81373 63165639
Endophthalmitis 25.91 9.56 48 241962 3544 63243468
Abscess bacterial 25.90 9.56 14 241996 212 63246800
Cell marker increased 25.86 9.56 15 241995 262 63246750
Sneezing 25.82 9.56 19 241991 18199 63228813
Ileus paralytic 25.81 9.56 55 241955 4496 63242516
B-cell lymphoma refractory 25.75 9.56 11 241999 95 63246917
Bone erosion 25.74 9.56 18 241992 17699 63229313
Intestinal perforation 25.72 9.56 102 241908 11861 63235151
Pseudarthrosis 25.71 9.56 18 241992 441 63246571
Hernia 25.61 9.56 8 242002 12566 63234446
Atrial septal defect 25.57 9.56 71 241939 6867 63240145
Gastrointestinal disorder congenital 25.57 9.56 12 241998 132 63246880
Smooth muscle cell neoplasm 25.53 9.56 23 241987 818 63246194
Orthostatic hypotension 25.52 9.56 63 241947 36097 63210915
Rhinocerebral mucormycosis 25.50 9.56 18 241992 447 63246565
Pneumonia adenoviral 25.49 9.56 12 241998 133 63246879
Microtia 25.48 9.56 17 241993 384 63246628
Lung adenocarcinoma 25.44 9.56 55 241955 4542 63242470
Adverse event 25.41 9.56 152 241858 67407 63179605
Pulmonary cavitation 25.23 9.56 23 241987 831 63246181
Septic arthritis staphylococcal 25.22 9.56 18 241992 455 63246557
Hyperhidrosis 25.15 9.56 276 241734 107560 63139452
Gastroenteritis viral 25.14 9.56 32 241978 23668 63223344
Retroperitoneal abscess 25.13 9.56 13 241997 179 63246833
Quadrantanopia 25.11 9.56 8 242002 26 63246986
Macular pseudohole 25.02 9.56 6 242004 3 63247009
Generalised oedema 24.99 9.56 123 241887 15695 63231317
Fungal endocarditis 24.95 9.56 14 241996 229 63246783
Neutrophilic panniculitis 24.89 9.56 9 242001 47 63246965
Uterine haematoma 24.88 9.56 8 242002 27 63246985
Pulmonary alveolar haemorrhage 24.86 9.56 55 241955 4613 63242399
Lymphatic fistula 24.86 9.56 22 241988 764 63246248
Oropharyngeal pain 24.86 9.56 235 241775 94252 63152760
Exostosis 24.84 9.56 19 241991 17843 63229169
Blast crisis in myelogenous leukaemia 24.76 9.56 19 241991 538 63246474
Ileal ulcer 24.72 9.56 18 241992 470 63246542
Emotional disorder 24.71 9.56 10 242000 13369 63233643
Corynebacterium infection 24.70 9.56 19 241991 540 63246472
Infected skin ulcer 24.66 9.56 37 241973 2295 63244717
Pneumonia pneumococcal 24.65 9.56 36 241974 2179 63244833
Steroid dependence 24.65 9.56 32 241978 1732 63245280
Atypical fracture 24.63 9.56 20 241990 616 63246396
Fungal test positive 24.61 9.56 19 241991 543 63246469
Deformity 24.59 9.56 7 242003 11677 63235335
Coeliac disease 24.57 9.56 9 242001 12788 63234224
Hypocomplementaemia 24.57 9.56 13 241997 188 63246824
Meconium stain 24.57 9.56 13 241997 188 63246824
Respiratory arrest 24.54 9.56 55 241955 32590 63214422
Lung consolidation 24.54 9.56 51 241959 4097 63242915
Mobility decreased 24.47 9.56 320 241690 120839 63126173
Coxsackie viral infection 24.45 9.56 8 242002 29 63246983
Bladder agenesis 24.43 9.56 12 241998 147 63246865
Sleep disorder due to a general medical condition 24.39 9.56 8 242002 12180 63234832
Blister 24.38 9.56 348 241662 129466 63117546
Left ventricular hypertrophy 24.33 9.56 59 241951 5256 63241756
Brain stem infarction 24.31 9.56 22 241988 787 63246225
Focal segmental glomerulosclerosis 24.31 9.56 29 241981 1439 63245573
Campylobacter infection 24.29 9.56 25 241985 1051 63245961
Peripheral T-cell lymphoma unspecified 24.27 9.56 13 241997 193 63246819
Hepatosplenomegaly 24.18 9.56 39 241971 2575 63244437
Duodenal ulcer repair 24.14 9.56 9 242001 52 63246960
Limb hypoplasia congenital 24.10 9.56 13 241997 196 63246816
Limb discomfort 24.07 9.56 48 241962 29668 63217344
Pneumonia chlamydial 24.07 9.56 10 242000 80 63246932
Colitis 24.06 9.56 287 241723 48241 63198771
Blood alkaline phosphatase increased 23.96 9.56 260 241750 42707 63204305
Genitalia external ambiguous 23.94 9.56 12 241998 154 63246858
Mediastinitis 23.92 9.56 13 241997 199 63246813
Locked-in syndrome 23.91 9.56 17 241993 427 63246585
Nephritis 23.91 9.56 38 241972 2478 63244534
Umbilical cord abnormality 23.90 9.56 20 241990 643 63246369
Blood calcium decreased 23.85 9.56 40 241970 26411 63220601
Metaphyseal corner fracture 23.83 9.56 8 242002 32 63246980
Impaired work ability 23.78 9.56 19 241991 17456 63229556
Epstein-Barr viraemia 23.77 9.56 24 241986 986 63246026
Epstein-Barr virus associated lymphoma 23.76 9.56 18 241992 500 63246512
Adverse drug reaction 23.74 9.56 192 241818 79522 63167490
Acute graft versus host disease in liver 23.69 9.56 20 241990 651 63246361
Gestational hypertension 23.66 9.56 37 241973 2380 63244632
Enterocolitis viral 23.62 9.56 14 241996 255 63246757
Ureterolithiasis 23.60 9.56 33 241977 1919 63245093
Blood pressure diastolic abnormal 23.58 9.56 13 241997 14529 63232483
Femoral hernia incarcerated 23.58 9.56 22 241988 819 63246193
Subileus 23.58 9.56 43 241967 3136 63243876
Muscle spasticity 23.56 9.56 29 241981 21765 63225247
Myelosuppression 23.54 9.56 163 241847 23540 63223472
Ophthalmic herpes zoster 23.52 9.56 34 241976 2039 63244973
Deafness neurosensory 23.42 9.56 55 241955 4800 63242212
Calciphylaxis 23.36 9.56 42 241968 3030 63243982
Meningoencephalitis herpetic 23.33 9.56 26 241984 1198 63245814
Infective tenosynovitis 23.31 9.56 15 241995 318 63246694
Caudal regression syndrome 23.22 9.56 12 241998 165 63246847
Post procedural hypothyroidism 23.15 9.56 14 241996 265 63246747
Coloboma 23.15 9.56 10 242000 89 63246923
Gastrointestinal perforation 23.14 9.56 45 241965 3446 63243566
Legionella infection 23.04 9.56 17 241993 453 63246559
Skin mass 23 9.56 62 241948 5893 63241119
Upper limb fracture 22.96 9.56 23 241987 18945 63228067
Ruptured cerebral aneurysm 22.92 9.56 17 241993 457 63246555
Conjunctival oedema 22.91 9.56 20 241990 682 63246330
Autoimmune hepatitis 22.88 9.56 78 241932 8432 63238580
Nocardia sepsis 22.87 9.56 5 242005 0 63247012
Diffuse panbronchiolitis 22.87 9.56 5 242005 0 63247012
Skin erosion 22.85 9.56 38 241972 2574 63244438
Panic attack 22.82 9.56 31 241979 22300 63224712
Visual acuity reduced 22.81 9.56 152 241858 21674 63225338
Cellulitis 22.78 9.56 439 241571 81519 63165493
Lymphocyte count decreased 22.75 9.56 195 241815 30062 63216950
Tissue infiltration 22.73 9.56 19 241991 610 63246402
Device related infection 22.72 9.56 160 241850 23232 63223780
Antinuclear antibody negative 22.72 9.56 13 241997 221 63246791
Infectious thyroiditis 22.64 9.56 7 242003 20 63246992
Encapsulating peritoneal sclerosis 22.63 9.56 15 241995 335 63246677
Shock haemorrhagic 22.61 9.56 86 241924 9809 63237203
Trichosporon infection 22.56 9.56 14 241996 278 63246734
Micrognathia 22.56 9.56 14 241996 278 63246734
Eye infection fungal 22.52 9.56 11 241999 133 63246879
Haematuria 22.50 9.56 189 241821 28968 63218044
Cerebellar stroke 22.47 9.56 14 241996 280 63246732
Retching 22.46 9.56 14 241996 14631 63232381
Chest X-ray abnormal 22.45 9.56 52 241958 4497 63242515
Head injury 22.41 9.56 44 241966 27352 63219660
Haemobilia 22.40 9.56 10 242000 97 63246915
Myositis 22.39 9.56 82 241928 9184 63237828
Pneumonia pseudomonal 22.36 9.56 37 241973 2496 63244516
Uveitis 22.31 9.56 101 241909 12452 63234560
Febrile bone marrow aplasia 22.26 9.56 70 241940 7255 63239757
Glomerulonephritis rapidly progressive 22.25 9.56 23 241987 972 63246040
Idiopathic pulmonary fibrosis 22.24 9.56 27 241983 1365 63245647
Peritoneal tuberculosis 22.23 9.56 17 241993 479 63246533
DNA antibody positive 22.21 9.56 15 241995 346 63246666
Juvenile idiopathic arthritis 22.20 9.56 43 241967 3283 63243729
Monoclonal B-cell lymphocytosis 22.09 9.56 8 242002 42 63246970
Candida infection 22.00 9.56 184 241826 28167 63218845
External auditory canal atresia 21.99 9.56 9 242001 69 63246943
Product storage error 21.99 9.56 15 241995 14941 63232071
Cutaneous T-cell lymphoma stage IV 21.98 9.56 6 242004 9 63247003
Pneumocystis test positive 21.98 9.56 6 242004 9 63247003
Malaise 21.94 9.56 1330 240680 414624 62832388
Hyperuricaemia 21.85 9.56 57 241953 5313 63241699
Anal abscess 21.83 9.56 52 241958 4580 63242432
Lung transplant rejection 21.77 9.56 22 241988 905 63246107
Human herpesvirus 6 infection reactivation 21.73 9.56 15 241995 359 63246653
Hepatic fibrosis 21.72 9.56 45 241965 3607 63243405
Lip swelling 21.71 9.56 197 241813 30866 63216146
Nuchal rigidity 21.71 9.56 19 241991 650 63246362
Congenital genital malformation 21.69 9.56 11 241999 145 63246867
Morganella infection 21.66 9.56 19 241991 652 63246360
Limb injury 21.64 9.56 40 241970 25437 63221575
Temperature intolerance 21.59 9.56 4 242006 8960 63238052
Putamen haemorrhage 21.56 9.56 12 241998 193 63246819
Placental insufficiency 21.49 9.56 27 241983 1414 63245598
Gastropleural fistula 21.49 9.56 8 242002 46 63246966
Head deformity 21.47 9.56 10 242000 108 63246904
Renal artery thrombosis 21.47 9.56 10 242000 108 63246904
Blood fibrinogen decreased 21.43 9.56 21 241989 832 63246180
Ligament sprain 21.41 9.56 11 241999 12789 63234223
Facial paralysis 21.35 9.56 108 241902 13933 63233079
Neutrophilia 21.34 9.56 50 241960 4356 63242656
Haematemesis 21.32 9.56 193 241817 30219 63216793
IgA nephropathy 21.29 9.56 18 241992 587 63246425
Thyroid disorder 21.25 9.56 16 241994 15146 63231866
Complication associated with device 21.24 9.56 20 241990 16958 63230054
Adenoviral haemorrhagic cystitis 21.23 9.56 11 241999 152 63246860
Renal tubular atrophy 21.18 9.56 20 241990 756 63246256
Bacteriuria 21.17 9.56 23 241987 1030 63245982
Leishmaniasis 21.14 9.56 9 242001 77 63246935
Hypersensitivity pneumonitis 21.14 9.56 37 241973 2613 63244399
Viral haemorrhagic cystitis 21.10 9.56 21 241989 848 63246164
Cytomegalovirus oesophagitis 21.09 9.56 13 241997 255 63246757
Paradoxical drug reaction 21.09 9.56 48 241962 4104 63242908
Lupus enteritis 21.07 9.56 8 242002 49 63246963
Varicella 21.06 9.56 31 241979 1890 63245122
Acute on chronic liver failure 21.03 9.56 12 241998 203 63246809
Glomerulonephritis membranoproliferative 20.98 9.56 12 241998 204 63246808
Meningoencephalitis bacterial 20.94 9.56 9 242001 79 63246933
Mucinous adenocarcinoma of appendix 20.90 9.56 6 242004 12 63247000
Hypertelorism 20.89 9.56 16 241994 452 63246560
Renal abscess 20.88 9.56 20 241990 770 63246242
Underdose 20.85 9.56 46 241964 27410 63219602
Intestinal tuberculosis 20.84 9.56 9 242001 80 63246932
Aortic aneurysm rupture 20.79 9.56 17 241993 529 63246483
Optic atrophy 20.76 9.56 25 241985 1253 63245759
Anterograde amnesia 20.76 9.56 17 241993 530 63246482
Cryoglobulinaemia 20.73 9.56 16 241994 457 63246555
Pulmonary artery thrombosis 20.73 9.56 19 241991 691 63246321
Oliguria 20.71 9.56 79 241931 9022 63237990
Coagulation test abnormal 20.71 9.56 20 241990 778 63246234
COVID-19 pneumonia 20.70 9.56 108 241902 14101 63232911
Blood cholesterol increased 20.63 9.56 244 241766 93788 63153224
Anhedonia 20.60 9.56 8 242002 10966 63236046
Bronchostenosis 20.58 9.56 16 241994 462 63246550
Bone infarction 20.58 9.56 14 241996 327 63246685
Seasonal allergy 20.49 9.56 30 241980 20920 63226092
Pregnancy on contraceptive 20.49 9.56 24 241986 1168 63245844
Duodenal ulcer perforation 20.42 9.56 223 241787 86986 63160026
Tethered cord syndrome 20.40 9.56 13 241997 271 63246741
Knee arthroplasty 20.36 9.56 122 241888 54084 63192928
Patent ductus arteriosus 20.34 9.56 48 241962 4202 63242810
Hospice care 20.31 9.56 3 242007 7929 63239083
Veillonella infection 20.29 9.56 7 242003 31 63246981
Infusion site swelling 20.29 9.56 6 242004 9764 63237248
Intrauterine infection 20.26 9.56 10 242000 124 63246888
Arthritis reactive 20.23 9.56 15 241995 403 63246609
Cardiovascular disorder 20.22 9.56 94 241916 11718 63235294
Aspergillus test positive 20.17 9.56 14 241996 338 63246674
Ocular lymphoma 20.17 9.56 8 242002 56 63246956
Cleft palate 20.16 9.56 22 241988 990 63246022
Streptococcal infection 20.13 9.56 58 241952 5729 63241283
Autoimmune disorder 20.03 9.56 123 241887 17054 63229958
Glossopharyngeal nerve paralysis 19.94 9.56 5 242005 4 63247008
Pelvic deformity 19.94 9.56 12 241998 225 63246787
Arterial thrombosis 19.89 9.56 26 241984 1417 63245595
Deep vein thrombosis postoperative 19.85 9.56 91 241919 11278 63235734
Otospondylomegaepiphyseal dysplasia 19.84 9.56 9 242001 91 63246921
Malacoplakia vesicae 19.81 9.56 8 242002 59 63246953
Staphylococcal bacteraemia 19.80 9.56 56 241954 5474 63241538
Pericarditis constrictive 19.78 9.56 14 241996 349 63246663
Gastrointestinal malformation 19.76 9.56 11 241999 177 63246835
Poisoning deliberate 19.74 9.56 9 242001 11209 63235803
Renal cell carcinoma 19.73 9.56 41 241969 3294 63243718
Ganglioneuroma 19.71 9.56 10 242000 132 63246880
Myasthenia gravis crisis 19.62 9.56 16 241994 496 63246516
Infective spondylitis 19.60 9.56 11 241999 180 63246832
Herpes zoster meningoencephalitis 19.59 9.56 13 241997 291 63246721
Bacillus infection 19.58 9.56 20 241990 833 63246179
Threatened labour 19.57 9.56 20 241990 834 63246178
Nail pigmentation 19.54 9.56 11 241999 181 63246831
Skin discolouration 19.53 9.56 76 241934 37752 63209260
Large intestine infection 19.53 9.56 30 241980 1900 63245112
Leiomyoma 19.51 9.56 15 241995 426 63246586
Tooth fracture 19.41 9.56 9 242001 11101 63235911
Diarrhoea haemorrhagic 19.36 9.56 77 241933 8965 63238047
Complement factor decreased 19.36 9.56 8 242002 63 63246949
Congenital coronary artery malformation 19.31 9.56 10 242000 138 63246874
Basal ganglion degeneration 19.30 9.56 15 241995 433 63246579
Blood pressure diastolic increased 19.29 9.56 7 242003 10003 63237009
Pneumonia acinetobacter 19.29 9.56 7 242003 37 63246975
Encephalitis autoimmune 19.29 9.56 26 241984 1460 63245552
Congenital ectopic bladder 19.25 9.56 9 242001 98 63246914
Atypical mycobacterial pneumonia 19.19 9.56 6 242004 18 63246994
Device breakage 19.18 9.56 10 242000 11532 63235480
Urticaria 19.18 9.56 483 241527 165319 63081693
Anaplastic large-cell lymphoma 19.17 9.56 9 242001 99 63246913
Glomerulonephritis membranous 19.15 9.56 17 241993 593 63246419
Ileal perforation 19.13 9.56 15 241995 439 63246573
Nerve injury 19.09 9.56 7 242003 9939 63237073
Rectal cancer metastatic 19.09 9.56 12 241998 244 63246768
Feeling hot 19.09 9.56 113 241897 50241 63196771
Histoplasmosis 19.05 9.56 30 241980 1941 63245071
Haemolysis 19.05 9.56 63 241947 6705 63240307
Dysphonia 19.05 9.56 105 241905 47509 63199503
C-reactive protein 19.03 9.56 51 241959 4831 63242181
Glomerulonephritis proliferative 19.02 9.56 11 241999 191 63246821
Granuloma skin 19.00 9.56 73 241937 8364 63238648
Keratitis 19 9.56 41 241969 3381 63243631
Systemic scleroderma 18.98 9.56 21 241989 960 63246052
Laryngitis 18.96 9.56 22 241988 16945 63230067
Lymphoplasmacytoid lymphoma/immunocytoma 18.95 9.56 5 242005 6 63247006
Thoracic vertebral fracture 18.95 9.56 49 241961 4543 63242469
Disease progression 18.92 9.56 607 241403 122151 63124861
Bacterial vulvovaginitis 18.89 9.56 19 241991 777 63246235
Wound dehiscence 18.89 9.56 51 241959 4852 63242160
Macular fibrosis 18.88 9.56 14 241996 376 63246636
Blood immunoglobulin M decreased 18.86 9.56 21 241989 967 63246045
Microangiopathic haemolytic anaemia 18.84 9.56 17 241993 606 63246406
Torsade de pointes 18.83 9.56 14 241996 13337 63233675
Eye abscess 18.82 9.56 10 242000 146 63246866
Epstein-Barr virus test positive 18.79 9.56 17 241993 608 63246404
Corneal scar 18.79 9.56 9 242001 104 63246908
Congenital oral malformation 18.77 9.56 11 241999 196 63246816
Postoperative wound infection 18.75 9.56 87 241923 10838 63236174
Gingivitis ulcerative 18.72 9.56 11 241999 197 63246815
Bulbar palsy 18.72 9.56 6 242004 20 63246992
Graft versus host disease in skin 18.71 9.56 37 241973 2868 63244144
Gram stain positive 18.69 9.56 7 242003 41 63246971
Product substitution issue 18.68 9.56 20 241990 15976 63231036
Abdominal tenderness 18.68 9.56 71 241939 8095 63238917
Caesarean section 18.64 9.56 120 241890 16912 63230100
Dermatitis allergic 18.64 9.56 110 241900 15038 63231974
Extrapyramidal disorder 18.64 9.56 14 241996 13270 63233742
Respiratory gas exchange disorder 18.63 9.56 14 241996 384 63246628
Plasma cell myeloma 18.63 9.56 72 241938 35833 63211179
Status asthmaticus 18.62 9.56 20 241990 884 63246128
Concussion 18.62 9.56 6 242004 9238 63237774
Pneumonia staphylococcal 18.58 9.56 37 241973 2883 63244129
Rhegmatogenous retinal detachment 18.56 9.56 9 242001 107 63246905
Granulomatosis with polyangiitis 18.56 9.56 32 241978 2233 63244779
Aplastic anaemia 18.53 9.56 79 241931 9490 63237522
Chest discomfort 18.52 9.56 301 241709 109668 63137344
Pseudomonal sepsis 18.48 9.56 33 241977 2368 63244644
Rheumatic disorder 18.44 9.56 38 241972 3034 63243978
Blood lactate dehydrogenase decreased 18.42 9.56 9 242001 109 63246903
Complications of transplanted liver 18.41 9.56 14 241996 391 63246621
Hydrocephalus 18.32 9.56 53 241957 5247 63241765
Akathisia 18.31 9.56 6 242004 9140 63237872
Renal infarct 18.30 9.56 25 241985 1422 63245590
Adactyly 18.28 9.56 7 242003 44 63246968
Brain compression 18.26 9.56 14 241996 396 63246616
Lymphoma transformation 18.24 9.56 10 242000 156 63246856
Encephalomyelitis 18.20 9.56 9 242001 112 63246900
Ureaplasma infection 18.20 9.56 17 241993 634 63246378
Tracheobronchitis 18.19 9.56 23 241987 1212 63245800
Keratitis fungal 18.18 9.56 10 242000 157 63246855
Ileus 18.17 9.56 107 241903 14618 63232394
Femur fracture 18.16 9.56 241 241769 41515 63205497
Lipomatosis 18.15 9.56 7 242003 45 63246967
Megakaryocytes increased 18.15 9.56 7 242003 45 63246967
Hypopharyngeal cancer 18.12 9.56 5 242005 8 63247004
Cytomegalovirus gastrointestinal ulcer 18.12 9.56 5 242005 8 63247004
Poor quality sleep 18.11 9.56 30 241980 19905 63227107
Haemorrhagic diathesis 18.10 9.56 47 241963 4368 63242644
Terminal ileitis 18.06 9.56 18 241992 728 63246284
Coronavirus infection 18.01 9.56 46 241964 4232 63242780
Intervertebral disc degeneration 18.01 9.56 20 241990 15712 63231300
Product prescribing error 18.00 9.56 166 241844 26123 63220889
Haptoglobin decreased 18.00 9.56 18 241992 731 63246281
Pleocytosis 17.94 9.56 19 241991 826 63246186
Leiomyosarcoma 17.92 9.56 11 241999 214 63246798
Protein-losing gastroenteropathy 17.92 9.56 11 241999 214 63246798
HELLP syndrome 17.91 9.56 21 241989 1023 63245989
Neutropenic infection 17.87 9.56 24 241986 1343 63245669
Duodenal ulcer haemorrhage 17.83 9.56 33 241977 2434 63244578
Venous thrombosis limb 17.81 9.56 37 241973 2971 63244041
Blood test abnormal 17.75 9.56 20 241990 15609 63231403
Herpes virus infection 17.72 9.56 54 241956 5502 63241510
Scleral disorder 17.72 9.56 9 242001 119 63246893
Reticulocytopenia 17.71 9.56 8 242002 80 63246932
Periodontitis 17.69 9.56 39 241971 3264 63243748
Fungal sepsis 17.68 9.56 23 241987 1247 63245765
B-cell lymphoma 17.67 9.56 39 241971 3266 63243746
Beta 2 microglobulin urine increased 17.65 9.56 7 242003 49 63246963
Mucocutaneous ulceration 17.58 9.56 10 242000 168 63246844
Abscess rupture 17.57 9.56 12 241998 282 63246730
Abdominal compartment syndrome 17.57 9.56 16 241994 577 63246435
Polyarthritis 17.56 9.56 81 241929 10065 63236947
Airway peak pressure increased 17.54 9.56 12 241998 283 63246729
Cardiac myxoma 17.53 9.56 11 241999 223 63246789
PO2 decreased 17.52 9.56 25 241985 1481 63245531
Ankylosing spondylitis 17.52 9.56 9 242001 10465 63236547
Retinal haemorrhage 17.48 9.56 50 241960 4919 63242093
Pneumonia aspiration 17.44 9.56 205 241805 34335 63212677
Cytomegalovirus duodenitis 17.41 9.56 5 242005 10 63247002
Tongue necrosis 17.41 9.56 5 242005 10 63247002
Omental necrosis 17.41 9.56 5 242005 10 63247002
Disseminated varicella zoster vaccine virus infection 17.41 9.56 7 242003 51 63246961
Skin striae 17.41 9.56 24 241986 1377 63245635
Mycobacterium kansasii infection 17.40 9.56 9 242001 124 63246888
Fracture 17.33 9.56 131 241879 19453 63227559
Ureteral necrosis 17.29 9.56 7 242003 52 63246960
Squamous cell carcinoma 17.29 9.56 72 241938 8560 63238452
Condition aggravated 17.24 9.56 1768 240242 400449 62846563
Needle issue 17.23 9.56 9 242001 10367 63236645
Mouth ulceration 17.21 9.56 197 241813 32787 63214225
Small cell lung cancer 17.20 9.56 26 241984 1623 63245389
Paraplegia 17.17 9.56 34 241976 2638 63244374
Cerebellar infarction 17.17 9.56 29 241981 1990 63245022
Blood lactate dehydrogenase abnormal 17.13 9.56 13 241997 362 63246650
Aplasia 17.12 9.56 45 241965 4214 63242798
Anencephaly 17.10 9.56 12 241998 295 63246717
Chronic hepatitis C 17.08 9.56 10 242000 178 63246834
Mesangioproliferative glomerulonephritis 17.07 9.56 7 242003 54 63246958
Vertigo 17.04 9.56 146 241864 59741 63187271
Epistaxis 17.01 9.56 186 241824 72539 63174473
Uterine perforation 17.00 9.56 3 242007 6960 63240052
Chest pain 16.98 9.56 662 241348 215297 63031715
Megacolon 16.94 9.56 28 241982 1887 63245125
Renal dysplasia 16.94 9.56 11 241999 237 63246775
Cytomegalovirus gastritis 16.93 9.56 10 242000 181 63246831
Chronic gastritis 16.89 9.56 35 241975 2806 63244206
Autoimmune haemolytic anaemia 16.87 9.56 47 241963 4554 63242458
Hodgkin's disease 16.84 9.56 18 241992 791 63246221
Ophthalmic herpes simplex 16.84 9.56 14 241996 446 63246566
Basal cell carcinoma 16.84 9.56 172 241838 27819 63219193
Ulcerative keratitis 16.84 9.56 34 241976 2676 63244336
Alternaria infection 16.82 9.56 11 241999 240 63246772
Pain in jaw 16.81 9.56 97 241913 43399 63203613
Cutaneous leishmaniasis 16.81 9.56 8 242002 91 63246921
Tooth dislocation 16.81 9.56 6 242004 30 63246982
Duodenal stenosis 16.80 9.56 15 241995 527 63246485
Hypozincaemia 16.79 9.56 5 242005 12 63247000
Enterovirus infection 16.74 9.56 20 241990 994 63246018
Pustular psoriasis 16.71 9.56 47 241963 4579 63242433
Histoplasmosis disseminated 16.69 9.56 24 241986 1432 63245580
Cryptosporidiosis infection 16.69 9.56 12 241998 307 63246705
Pulmonary sepsis 16.66 9.56 25 241985 1551 63245461
Hypochromic anaemia 16.65 9.56 28 241982 1914 63245098
Pharyngitis streptococcal 16.65 9.56 10 242000 10662 63236350
Respiratory tract infection 16.64 9.56 236 241774 41247 63205765
Post herpetic neuralgia 16.64 9.56 30 241980 2169 63244843
Asteatosis 16.64 9.56 7 242003 58 63246954
Live birth 16.63 9.56 160 241850 25470 63221542
Diffuse alveolar damage 16.63 9.56 19 241991 900 63246112
Graft complication 16.62 9.56 11 241999 245 63246767
Pustule 16.62 9.56 26 241984 1673 63245339
Large intestinal ulcer 16.59 9.56 39 241971 3405 63243607
PCO2 increased 16.57 9.56 22 241988 1217 63245795
Gastrointestinal haemorrhage 16.57 9.56 416 241594 80760 63166252
Glucose tolerance impaired 16.57 9.56 59 241951 6518 63240494
Blastomycosis 16.55 9.56 12 241998 311 63246701
Coma 16.54 9.56 161 241849 64203 63182809
Congenital cytomegalovirus infection 16.51 9.56 5 242005 13 63246999
Retinal drusen 16.51 9.56 5 242005 13 63246999
Parvimonas micra infection 16.51 9.56 5 242005 13 63246999
Oesophageal perforation 16.47 9.56 13 241997 384 63246628
Rhabdomyolysis 16.46 9.56 99 241911 43852 63203160
Rash vesicular 16.46 9.56 45 241965 4313 63242699
Iris transillumination defect 16.43 9.56 8 242002 96 63246916
Abortion missed 16.39 9.56 26 241984 1693 63245319
Cytokine release syndrome 16.38 9.56 102 241908 14212 63232800
Abdominal abscess 16.37 9.56 46 241964 4480 63242532
Extradural abscess 16.33 9.56 19 241991 918 63246094
Intestinal ischaemia 16.32 9.56 64 241946 7404 63239608
Increased tendency to bruise 16.31 9.56 10 242000 10542 63236470
Squamous cell carcinoma of skin 16.31 9.56 56 241954 6076 63240936
Creatinine renal clearance decreased 16.30 9.56 23 241987 16285 63230727
Tardive dyskinesia 16.29 9.56 6 242004 8496 63238516
Necrosis 16.28 9.56 52 241958 5435 63241577
Still's disease 16.25 9.56 5 242005 14 63246998
Thrombocytosis 16.24 9.56 54 241956 5764 63241248
Dengue fever 16.22 9.56 16 241994 639 63246373
Osteopenia 16.21 9.56 130 241880 19655 63227357
Jejunal ulcer perforation 16.19 9.56 6 242004 34 63246978
Premature separation of placenta 16.18 9.56 27 241983 1834 63245178
Musculoskeletal disorder 16.16 9.56 34 241976 20610 63226402
Sudden hearing loss 16.16 9.56 22 241988 1247 63245765
Brain oedema 16.15 9.56 101 241909 14094 63232918
Abdominal wall abscess 16.14 9.56 18 241992 830 63246182
Infective aneurysm 16.13 9.56 13 241997 396 63246616
Gastric cancer 16.11 9.56 47 241963 4676 63242336
Device malfunction 16.11 9.56 27 241983 17830 63229182
Osteomyelitis bacterial 16.10 9.56 10 242000 199 63246813
Nodal marginal zone B-cell lymphoma 16.07 9.56 4 242006 3 63247009
Portal vein stenosis 16.07 9.56 4 242006 3 63247009
Dermatitis psoriasiform 16.06 9.56 30 241980 2229 63244783
Central nervous system infection 16.05 9.56 17 241993 739 63246273
Localised infection 16.05 9.56 60 241950 30150 63216862
Vomiting 16.05 9.56 1878 240132 557739 62689273
Multiple sclerosis 16.02 9.56 44 241966 24328 63222684
Food allergy 16.02 9.56 12 241998 11389 63235623
Subclavian artery embolism 15.99 9.56 5 242005 15 63246997
Fear 15.99 9.56 22 241988 15744 63231268
Pelvic venous thrombosis 15.99 9.56 26 241984 1729 63245283
Influenza B virus test positive 15.98 9.56 11 241999 262 63246750
Bladder transitional cell carcinoma 15.97 9.56 16 241994 651 63246361
Evans syndrome 15.97 9.56 10 242000 202 63246810
Neutropenic colitis 15.96 9.56 36 241974 3059 63243953
Infusion site extravasation 15.95 9.56 10 242000 10416 63236596
Cryptococcal meningoencephalitis 15.94 9.56 8 242002 103 63246909
Leukaemia cutis 15.94 9.56 8 242002 103 63246909
Prinzmetal angina 15.91 9.56 17 241993 747 63246265
Aortic arteriosclerosis 15.90 9.56 56 241954 6153 63240859
Nasal septum disorder 15.89 9.56 9 242001 150 63246862
Subclavian vein thrombosis 15.88 9.56 27 241983 1863 63245149
Abscess neck 15.85 9.56 16 241994 657 63246355
Histiocytic sarcoma 15.85 9.56 7 242003 66 63246946
Pseudomembranous colitis 15.83 9.56 36 241974 3076 63243936
Cardio-respiratory arrest 15.82 9.56 149 241861 59810 63187202
Oral mucosa erosion 15.82 9.56 21 241989 1162 63245850
Stenotrophomonas infection 15.78 9.56 28 241982 1999 63245013
Congenital hydronephrosis 15.77 9.56 13 241997 409 63246603
Giant cell arteritis 15.76 9.56 30 241980 2261 63244751
Cytomegalovirus mucocutaneous ulcer 15.75 9.56 5 242005 16 63246996
Pelvic pain 15.68 9.56 17 241993 13502 63233510
Amniotic fluid volume increased 15.68 9.56 9 242001 154 63246858
Actinomycotic sepsis 15.67 9.56 8 242002 107 63246905
Salmonellosis 15.66 9.56 21 241989 1173 63245839
Scratch 15.66 9.56 3 242007 6562 63240450
Poor venous access 15.64 9.56 20 241990 14765 63232247
Stress fracture 15.62 9.56 66 241944 7897 63239115
Small intestinal ulcer haemorrhage 15.58 9.56 7 242003 69 63246943
Cushing's syndrome 15.58 9.56 16 241994 671 63246341
Hypoproteinaemia 15.56 9.56 28 241982 2021 63244991
Reticulin increased 15.54 9.56 4 242006 4 63247008
Infusion site erythema 15.52 9.56 13 241997 11666 63235346
Small intestine ulcer 15.48 9.56 12 241998 345 63246667
Lung lobectomy 15.48 9.56 8 242002 110 63246902
Body temperature decreased 15.46 9.56 34 241976 20285 63226727
Glomerulonephritis 15.44 9.56 26 241984 1780 63245232
Hepatic cyst 15.43 9.56 49 241961 5105 63241907
Mesenteric arterial occlusion 15.43 9.56 9 242001 159 63246853
Vitamin D decreased 15.42 9.56 10 242000 10232 63236780
Anastomotic stenosis 15.38 9.56 11 241999 279 63246733
Lymphangiectasia 15.32 9.56 7 242003 72 63246940
Red cell fragmentation syndrome 15.25 9.56 6 242004 41 63246971
Conjunctival ulcer 15.25 9.56 6 242004 41 63246971
Transient hypogammaglobulinaemia of infancy 15.25 9.56 6 242004 41 63246971
Keratitis bacterial 15.25 9.56 6 242004 41 63246971
Acute generalised exanthematous pustulosis 15.24 9.56 83 241927 11016 63235996
Anger 15.20 9.56 15 241995 12441 63234571
Immune-mediated myositis 15.20 9.56 22 241988 1321 63245691
Hepatitis acute 15.19 9.56 72 241938 9048 63237964
Clubbing 15.15 9.56 13 241997 433 63246579
Back injury 15.14 9.56 9 242001 9651 63237361
Fibrin degradation products increased 15.13 9.56 9 242001 165 63246847
Hepatic amoebiasis 15.10 9.56 5 242005 19 63246993
Phospholipidosis 15.09 9.56 9 242001 166 63246846
Vagus nerve paralysis 15.07 9.56 4 242006 5 63247007
Aspergillus test 15.07 9.56 4 242006 5 63247007
Tuberculosis gastrointestinal 15.02 9.56 12 241998 361 63246651
Diffuse large B-cell lymphoma stage IV 15.01 9.56 11 241999 290 63246722
Jejunal stenosis 15.00 9.56 6 242004 43 63246969
Blood cholinesterase decreased 14.98 9.56 8 242002 118 63246894
Joint tuberculosis 14.98 9.56 8 242002 118 63246894
Body height decreased 14.96 9.56 10 242000 10068 63236944
Eye irritation 14.95 9.56 39 241971 21932 63225080
Cough 14.89 9.56 939 241071 291804 62955208
Tubular breast carcinoma 14.89 9.56 6 242004 44 63246968
Myeloproliferative neoplasm 14.88 9.56 14 241996 527 63246485
Therapeutic response shortened 14.87 9.56 14 241996 11874 63235138
Sequestrectomy 14.82 9.56 17 241993 809 63246203
Frequent bowel movements 14.81 9.56 42 241968 22980 63224032
Aneurysm ruptured 14.81 9.56 14 241996 530 63246482
Poikilocytosis 14.81 9.56 9 242001 172 63246840
Neonatal respiratory distress syndrome 14.78 9.56 33 241977 2785 63244227
Seroma 14.77 9.56 28 241982 2103 63244909
Candida endophthalmitis 14.77 9.56 6 242004 45 63246967
Hip fracture 14.72 9.56 60 241950 29414 63217598
Acute graft versus host disease in intestine 14.71 9.56 25 241985 1724 63245288
Calculus urinary 14.69 9.56 22 241988 1362 63245650
Remission not achieved 14.69 9.56 8 242002 123 63246889
Deep vein thrombosis 14.69 9.56 421 241589 83379 63163633
Hysterectomy 14.68 9.56 9 242001 9490 63237522
Antimitochondrial antibody positive 14.68 9.56 7 242003 80 63246932
Enterovirus myocarditis 14.65 9.56 4 242006 6 63247006
Superinfection bacterial 14.63 9.56 15 241995 628 63246384
Drug reaction with eosinophilia and systemic symptoms 14.59 9.56 195 241815 33641 63213371
Henoch-Schonlein purpura 14.57 9.56 20 241990 1143 63245869
Hirsutism 14.56 9.56 22 241988 1373 63245639
Disability 14.55 9.56 30 241980 18317 63228695
Dystrophic calcification 14.52 9.56 8 242002 126 63246886
Leukocytosis 14.49 9.56 157 241853 25778 63221234
Toxoplasmosis 14.47 9.56 23 241987 1500 63245512
Pulmonary haemorrhage 14.46 9.56 60 241950 7121 63239891
Thrombophlebitis 14.45 9.56 43 241967 4325 63242687
Peritonitis viral 14.44 9.56 6 242004 48 63246964
Helicobacter gastritis 14.41 9.56 24 241986 1628 63245384
Intraductal papillary mucinous neoplasm 14.38 9.56 11 241999 310 63246702
Ulna fracture 14.37 9.56 20 241990 1158 63245854
Microscopic polyangiitis 14.36 9.56 9 242001 182 63246830
Non-Hodgkin's lymphoma 14.36 9.56 22 241988 1390 63245622
Impaired gastric emptying 14.36 9.56 11 241999 10321 63236691
Anal atresia 14.34 9.56 12 241998 386 63246626
Kidney rupture 14.33 9.56 6 242004 49 63246963
Appetite disorder 14.31 9.56 5 242005 7316 63239696
Haematoma infection 14.30 9.56 15 241995 645 63246367
Dyslipidaemia 14.29 9.56 61 241949 7332 63239680
Injection site discolouration 14.28 9.56 6 242004 7842 63239170
Pancreatic pseudocyst haemorrhage 14.27 9.56 4 242006 7 63247005
Parotid abscess 14.27 9.56 4 242006 7 63247005
Fibromyalgia 14.25 9.56 218 241792 80202 63166810
Tendon pain 14.25 9.56 36 241974 3290 63243722
Genital neoplasm malignant female 14.25 9.56 8 242002 131 63246881
Muscle haemorrhage 14.24 9.56 35 241975 3144 63243868
Lipohypertrophy 14.20 9.56 15 241995 650 63246362
Peritonsillar abscess 14.15 9.56 14 241996 561 63246451
Duodenal perforation 14.15 9.56 17 241993 850 63246162
Serratia infection 14.14 9.56 18 241992 955 63246057
Infective pulmonary exacerbation of cystic fibrosis 14.13 9.56 8 242002 8809 63238203
Pneumopericardium 14.13 9.56 6 242004 51 63246961
Gastroenteritis norovirus 14.12 9.56 27 241983 2041 63244971
Human polyomavirus infection 14.11 9.56 11 241999 319 63246693
Musculoskeletal pain 14.11 9.56 257 241753 92020 63154992
Lymphocytosis 14.06 9.56 32 241978 2735 63244277
Sensitivity to weather change 14.05 9.56 5 242005 7232 63239780
Hepatitis C RNA increased 14.04 9.56 8 242002 135 63246877
Gouty arthritis 14.03 9.56 14 241996 567 63246445
Spinal operation 13.99 9.56 7 242003 8264 63238748
Meningism 13.98 9.56 13 241997 482 63246530
Enterocolitis bacterial 13.97 9.56 10 242000 254 63246758
Abdominal distension 13.95 9.56 239 241771 86376 63160636
Gardner-Diamond syndrome 13.93 9.56 4 242006 8 63247004
Haematocolpos 13.93 9.56 6 242004 53 63246959
Toothache 13.90 9.56 33 241977 19166 63227846
Neural tube defect 13.90 9.56 9 242001 193 63246819
Lipodystrophy acquired 13.90 9.56 22 241988 1430 63245582
Product complaint 13.89 9.56 17 241993 12792 63234220
Skin necrosis 13.89 9.56 96 241914 13854 63233158
Amnesia 13.88 9.56 140 241870 55445 63191567
Immobile 13.86 9.56 52 241958 5891 63241121
Tibia fracture 13.83 9.56 47 241963 5073 63241939
Troponin I increased 13.81 9.56 28 241982 2210 63244802
Complications of transplanted lung 13.80 9.56 10 242000 259 63246753
Myelomalacia 13.74 9.56 6 242004 55 63246957
Flank pain 13.73 9.56 26 241984 16384 63230628
Malignant glaucoma 13.72 9.56 3 242007 0 63247012
Gastroenteritis sapovirus 13.72 9.56 3 242007 0 63247012
Anti-glomerular basement membrane antibody positive 13.72 9.56 3 242007 0 63247012
Glucose tolerance decreased 13.72 9.56 3 242007 0 63247012
Bezold abscess 13.72 9.56 3 242007 0 63247012
Intraductal papillary-mucinous carcinoma of pancreas 13.72 9.56 3 242007 0 63247012
Tuberculous tenosynovitis 13.72 9.56 3 242007 0 63247012
Endotoxic shock 13.72 9.56 3 242007 0 63247012
Chronic eosinophilic rhinosinusitis 13.72 9.56 3 242007 0 63247012
Scopulariopsis infection 13.72 9.56 3 242007 0 63247012
Meningoencephalitis amoebic 13.72 9.56 3 242007 0 63247012
Osteomyelitis salmonella 13.72 9.56 3 242007 0 63247012
Hyponatraemia 13.70 9.56 539 241471 111361 63135651
Vulval ulceration 13.68 9.56 11 241999 334 63246678
Kidney infection 13.68 9.56 44 241966 23132 63223880
Extranodal marginal zone B-cell lymphoma (MALT type) 13.67 9.56 13 241997 496 63246516
Upper-airway cough syndrome 13.65 9.56 14 241996 11404 63235608
Anal ulcer 13.63 9.56 14 241996 587 63246425
Aphonia 13.62 9.56 11 241999 10052 63236960
Picornavirus infection 13.61 9.56 4 242006 9 63247003
Conjunctival deposit 13.61 9.56 4 242006 9 63247003
Corectopia 13.61 9.56 4 242006 9 63247003
Sputum retention 13.61 9.56 14 241996 588 63246424
Otitis media acute 13.61 9.56 18 241992 992 63246020
Device leakage 13.61 9.56 5 242005 7091 63239921
Chronic graft versus host disease oral 13.58 9.56 8 242002 144 63246868
Acute hepatitis B 13.57 9.56 11 241999 338 63246674
Drug ineffective 13.56 9.56 3661 238349 1041104 62205908
Herpangina 13.54 9.56 5 242005 28 63246984
Vascular hyalinosis 13.54 9.56 5 242005 28 63246984
Rectal ulcer 13.52 9.56 20 241990 1225 63245787
Mouth injury 13.51 9.56 18 241992 999 63246013
Mood swings 13.51 9.56 31 241979 18217 63228795
Corneal epithelium defect 13.49 9.56 11 241999 341 63246671
Familial mediterranean fever 13.46 9.56 6 242004 58 63246954
Inguinal hernia 13.46 9.56 26 241984 1981 63245031
Gastroenteritis salmonella 13.45 9.56 15 241995 692 63246320
Eye disorder 13.44 9.56 43 241967 22642 63224370
Embolism venous 13.37 9.56 34 241976 3120 63243892
Red blood cell schistocytes present 13.35 9.56 10 242000 273 63246739
Keratopathy 13.35 9.56 14 241996 602 63246410
Upper respiratory tract infection 13.35 9.56 226 241784 81821 63165191
Exposure via body fluid 13.35 9.56 14 241996 602 63246410
Aphthous ulcer 13.34 9.56 95 241915 13843 63233169
Myelitis transverse 13.33 9.56 20 241990 1240 63245772
Cerebral fungal infection 13.31 9.56 7 242003 100 63246912
Vogt-Koyanagi-Harada disease 13.29 9.56 8 242002 150 63246862
Eosinophilic myocarditis 13.27 9.56 14 241996 606 63246406
Alpha haemolytic streptococcal infection 13.25 9.56 20 241990 1247 63245765
Acne 13.21 9.56 45 241965 23248 63223764
Nutritional condition abnormal 13.21 9.56 16 241994 807 63246205
Hypertrichosis 13.20 9.56 19 241991 1135 63245877
Dysplasia 13.20 9.56 17 241993 913 63246099
Rectal perforation 13.17 9.56 12 241998 433 63246579
Blood creatine phosphokinase decreased 13.16 9.56 13 241997 520 63246492
Hypersensitivity vasculitis 13.15 9.56 40 241970 4072 63242940
Vision blurred 13.14 9.56 259 241751 91665 63155347
Drug-induced liver injury 13.14 9.56 221 241789 40001 63207011
Urinary incontinence 13.13 9.56 70 241940 31944 63215068
Rheumatoid nodule 13.13 9.56 111 241899 17044 63229968
Bronchitis 13.12 9.56 369 241641 124566 63122446
Lupus myocarditis 13.11 9.56 6 242004 62 63246950
Abdominal pain upper 13.10 9.56 648 241362 205796 63041216
Transplant abscess 13.05 9.56 4 242006 11 63247001
Intra-abdominal haemorrhage 13.05 9.56 29 241981 2440 63244572
Toxic cardiomyopathy 13.02 9.56 8 242002 156 63246856
Exposure via breast milk 13.01 9.56 26 241984 2031 63244981
Abortion induced 13.01 9.56 75 241935 10167 63236845
Preterm premature rupture of membranes 13.01 9.56 21 241989 1388 63245624
Vascular pseudoaneurysm 13.00 9.56 22 241988 1512 63245500
Fungal skin infection 12.99 9.56 43 241967 4579 63242433
Beta-N-acetyl-D-glucosaminidase increased 12.98 9.56 5 242005 32 63246980
Parvovirus infection 12.98 9.56 10 242000 285 63246727
Endothelial dysfunction 12.97 9.56 8 242002 157 63246855
Retrognathia 12.97 9.56 12 241998 442 63246570
Cervical dysplasia 12.96 9.56 34 241976 3180 63243832
Jejunal perforation 12.95 9.56 7 242003 106 63246906
Sweat gland tumour 12.95 9.56 7 242003 106 63246906
Thrombotic thrombocytopenic purpura 12.92 9.56 38 241972 3798 63243214
Normochromic anaemia 12.89 9.56 10 242000 288 63246724
Cholecystitis acute 12.89 9.56 64 241946 8196 63238816
Steatohepatitis 12.88 9.56 14 241996 627 63246385
Cholecystectomy 12.86 9.56 13 241997 10664 63236348
Abortion spontaneous 12.84 9.56 252 241758 46943 63200069
Infected lymphocele 12.84 9.56 9 242001 221 63246791
Oral herpes 12.83 9.56 154 241856 25920 63221092
Infarction 12.83 9.56 30 241980 2611 63244401
Reactive gastropathy 12.81 9.56 12 241998 449 63246563
Febrile infection 12.76 9.56 22 241988 1535 63245477
Anal fistula 12.75 9.56 36 241974 3515 63243497
Gastrointestinal necrosis 12.74 9.56 31 241979 2767 63244245
Oral administration complication 12.72 9.56 7 242003 110 63246902
Chronic graft versus host disease in skin 12.68 9.56 15 241995 738 63246274
Peripheral circulatory failure 12.66 9.56 17 241993 951 63246061
Comminuted fracture 12.66 9.56 13 241997 545 63246467
Abdominal sepsis 12.64 9.56 20 241990 1299 63245713
Candida pneumonia 12.63 9.56 8 242002 165 63246847
Fluorosis 12.63 9.56 6 242004 68 63246944
Back disorder 12.62 9.56 14 241996 11003 63236009
Blood potassium decreased 12.61 9.56 101 241909 41925 63205087
Infective glossitis 12.60 9.56 5 242005 35 63246977
Aortic valve disease mixed 12.60 9.56 5 242005 35 63246977
Dermal sinus 12.60 9.56 5 242005 35 63246977
Cholecystitis infective 12.60 9.56 23 241987 1679 63245333
Dry throat 12.59 9.56 5 242005 6760 63240252
Hyperbilirubinaemia 12.56 9.56 80 241930 11234 63235778
Chorioretinal folds 12.56 9.56 4 242006 13 63246999
Meningitis enteroviral 12.56 9.56 4 242006 13 63246999
Large intestine erosion 12.56 9.56 4 242006 13 63246999
Face oedema 12.54 9.56 125 241885 20087 63226925
Vaginal discharge 12.52 9.56 10 242000 9188 63237824
Stenosis 12.52 9.56 21 241989 1433 63245579
Polyuria 12.50 9.56 65 241945 8477 63238535
B-lymphocyte count decreased 12.49 9.56 18 241992 1076 63245936
Injury 12.49 9.56 200 241810 73047 63173965
Gastric stenosis 12.47 9.56 6 242004 70 63246942
Rectal haemorrhage 12.45 9.56 123 241887 48907 63198105
Lactic acidosis 12.44 9.56 90 241920 38197 63208815
Immunodeficiency common variable 12.42 9.56 9 242001 233 63246779
Foetal death 12.41 9.56 78 241932 10902 63236110
Gastrointestinal erosion 12.41 9.56 14 241996 654 63246358
Angiosarcoma metastatic 12.40 9.56 6 242004 71 63246941
Enterocolitis haemorrhagic 12.39 9.56 21 241989 1445 63245567
Cell-mediated immune deficiency 12.37 9.56 5 242005 37 63246975
Depressed mood 12.34 9.56 96 241914 40095 63206917
Cranial sutures widening 12.33 9.56 4 242006 14 63246998
Mycetoma mycotic 12.33 9.56 4 242006 14 63246998
Peliosis hepatis 12.33 9.56 6 242004 72 63246940
Gouty tophus 12.33 9.56 9 242001 236 63246776
Respiratory tract infection fungal 12.32 9.56 12 241998 472 63246540
Serum sickness 12.30 9.56 31 241979 2829 63244183
Trichodysplasia spinulosa 12.30 9.56 13 241997 564 63246448
Eye infection 12.27 9.56 17 241993 12128 63234884
Female reproductive neoplasm 12.25 9.56 5 242005 38 63246974
Pseudo-Bartter syndrome 12.25 9.56 6 242004 73 63246939
Adenoviral hepatitis 12.24 9.56 11 241999 390 63246622
Hemianopia homonymous 12.24 9.56 14 241996 664 63246348
Gingivitis 12.23 9.56 64 241946 8365 63238647
Extremity necrosis 12.20 9.56 22 241988 1591 63245421
Strabismus 12.19 9.56 25 241985 1989 63245023
Product preparation error 12.19 9.56 4 242006 6088 63240924
Abscess intestinal 12.19 9.56 22 241988 1592 63245420
Parophthalmia 12.18 9.56 10 242000 313 63246699
Dysmorphism 12.17 9.56 27 241983 2269 63244743
Corneal abscess 12.14 9.56 5 242005 39 63246973
Vasogenic cerebral oedema 12.12 9.56 16 241994 880 63246132
Infective aortitis 12.12 9.56 4 242006 15 63246997
Pseudohypoaldosteronism 12.12 9.56 4 242006 15 63246997
Oesophageal squamous cell carcinoma stage IV 12.12 9.56 4 242006 15 63246997
Cryptococcus test positive 12.12 9.56 4 242006 15 63246997
Polymicrogyria 12.11 9.56 6 242004 75 63246937
Ovarian cancer 12.09 9.56 50 241960 5926 63241086
Irritability 12.08 9.56 71 241939 31623 63215389
Autoimmune thyroiditis 12.03 9.56 38 241972 3948 63243064
Gastrointestinal oedema 12.02 9.56 19 241991 1233 63245779
Intentional dose omission 12.00 9.56 8 242002 8067 63238945
Agitation 12.00 9.56 158 241852 59599 63187413
Haematoma 11.99 9.56 193 241817 34627 63212385
Dysbiosis 11.99 9.56 16 241994 890 63246122
Infection susceptibility increased 11.97 9.56 35 241975 3486 63243526
Serum ferritin increased 11.94 9.56 51 241959 6131 63240881
Iris hypopigmentation 11.92 9.56 4 242006 16 63246996
Tonsillar exudate 11.92 9.56 4 242006 16 63246996
Crime 11.92 9.56 4 242006 16 63246996
Pulmonary mucormycosis 11.91 9.56 10 242000 323 63246689
Aspergilloma 11.91 9.56 9 242001 249 63246763
Serositis 11.89 9.56 14 241996 685 63246327
Dysdiadochokinesis 11.88 9.56 7 242003 126 63246886
Clostridium colitis 11.87 9.56 24 241986 1890 63245122
Exposed bone in jaw 11.85 9.56 31 241979 2894 63244118
Herpes simplex hepatitis 11.85 9.56 11 241999 407 63246605
Uterine enlargement 11.84 9.56 19 241991 1249 63245763
Inappropriate antidiuretic hormone secretion 11.81 9.56 100 241910 15362 63231650
Gastrointestinal candidiasis 11.79 9.56 8 242002 186 63246826
Disseminated mycobacterium avium complex infection 11.79 9.56 7 242003 128 63246884
Renal graft infection 11.79 9.56 9 242001 253 63246759
Myalgia 11.77 9.56 448 241562 146081 63100931
Helicobacter test positive 11.75 9.56 12 241998 500 63246512
Menstruation irregular 11.74 9.56 6 242004 6998 63240014
Biliary anastomosis complication 11.72 9.56 5 242005 43 63246969
Epstein-Barr virus antigen positive 11.72 9.56 5 242005 43 63246969
Herpes simplex sepsis 11.72 9.56 5 242005 43 63246969
Eosinophilic pneumonia 11.72 9.56 26 241984 2185 63244827
Iris atrophy 11.71 9.56 6 242004 81 63246931
Vertebral artery occlusion 11.69 9.56 7 242003 130 63246882
Hepatic neoplasm 11.68 9.56 24 241986 1912 63245100
Muscle tightness 11.68 9.56 17 241993 11883 63235129
Right atrial hypertrophy 11.65 9.56 3 242007 3 63247009
Bowenoid papulosis 11.65 9.56 3 242007 3 63247009
Plasminogen decreased 11.65 9.56 3 242007 3 63247009
Herpes pharyngitis 11.65 9.56 3 242007 3 63247009
Thought broadcasting 11.65 9.56 3 242007 3 63247009
Conjunctival neoplasm 11.65 9.56 3 242007 3 63247009
Mean platelet volume 11.65 9.56 3 242007 3 63247009
Subacute hepatic failure 11.64 9.56 7 242003 131 63246881
Herpes zoster cutaneous disseminated 11.64 9.56 8 242002 190 63246822
Leukoderma 11.64 9.56 6 242004 82 63246930
Meningomyelitis herpes 11.62 9.56 5 242005 44 63246968
Appendicitis 11.61 9.56 62 241948 8167 63238845
Acute myeloid leukaemia 11.60 9.56 108 241902 17039 63229973
Spinal instability 11.60 9.56 7 242003 132 63246880
Acute lymphocytic leukaemia 11.59 9.56 28 241982 2488 63244524
Mucosal inflammation 11.59 9.56 247 241763 46681 63200331
Otitis media 11.58 9.56 43 241967 4848 63242164
Gastric perforation 11.57 9.56 22 241988 1657 63245355
Meningomyelocele 11.56 9.56 13 241997 605 63246407
Peptostreptococcus infection 11.53 9.56 5 242005 45 63246967
Lung disorder 11.53 9.56 315 241695 61946 63185066
Acute psychosis 11.53 9.56 28 241982 2497 63244515
Acute febrile neutrophilic dermatosis 11.52 9.56 31 241979 2943 63244069
Measles 11.50 9.56 8 242002 194 63246818
Haematotoxicity 11.48 9.56 68 241942 9308 63237704
Anaesthesia 11.47 9.56 11 241999 424 63246588
Protein urine present 11.45 9.56 50 241960 6070 63240942
Cholangitis acute 11.44 9.56 12 241998 516 63246496
Breast pain 11.44 9.56 10 242000 8788 63238224
Cancer in remission 11.43 9.56 5 242005 46 63246966
Tooth abscess 11.43 9.56 25 241985 14944 63232068
Duodenitis 11.40 9.56 36 241974 3739 63243273
Immune-mediated enterocolitis 11.39 9.56 25 241985 2086 63244926
Glucose urine present 11.37 9.56 14 241996 718 63246294
Emphysematous pyelonephritis 11.34 9.56 9 242001 268 63246744
Ureteric stenosis 11.34 9.56 13 241997 618 63246394
Orbital infection 11.34 9.56 5 242005 47 63246965
Feeding disorder 11.33 9.56 21 241989 13341 63233671
Atypical pneumonia 11.33 9.56 40 241970 4400 63242612
Extra dose administered 11.32 9.56 5 242005 6345 63240667
Thrombosis 11.32 9.56 176 241834 64579 63182433
Purulence 11.31 9.56 21 241989 1553 63245459
Haemarthrosis 11.31 9.56 32 241978 3129 63243883
Micturition urgency 11.24 9.56 12 241998 9599 63237413
Respiratory depression 11.24 9.56 22 241988 13693 63233319
Antinuclear antibody increased 11.22 9.56 19 241991 1306 63245706
Cafe au lait spots 11.20 9.56 4 242006 20 63246992
Malignant neoplasm of orbit 11.20 9.56 4 242006 20 63246992
Herpes simplex pneumonia 11.20 9.56 4 242006 20 63246992
Cellulitis orbital 11.20 9.56 12 241998 529 63246483
Tropical spastic paresis 11.19 9.56 3 242007 4 63247008
Fibrosarcoma 11.19 9.56 3 242007 4 63247008
Hypervolaemia 11.18 9.56 63 241947 28350 63218662
Pancreatic neoplasm 11.16 9.56 14 241996 732 63246280
Necrotising herpetic retinopathy 11.15 9.56 6 242004 90 63246922
Septic encephalopathy 11.15 9.56 6 242004 90 63246922
Acute disseminated encephalomyelitis 11.15 9.56 8 242002 204 63246808
Anal cancer 11.14 9.56 12 241998 532 63246480
Non-cardiac chest pain 11.09 9.56 5 242005 6267 63240745
Delayed graft function 11.07 9.56 17 241993 1076 63245936
Paraspinal abscess 11.07 9.56 5 242005 50 63246962
Acquired claw toe 11.05 9.56 8 242002 207 63246805
Pericardiotomy 11.04 9.56 4 242006 21 63246991
Bursitis infective 11.04 9.56 19 241991 1324 63245688
Lichenification 11.03 9.56 11 241999 445 63246567
Nerve compression 11.02 9.56 11 241999 9076 63237936
Coombs negative haemolytic anaemia 11.01 9.56 8 242002 208 63246804
Pulmonary infarction 11.01 9.56 29 241981 2718 63244294
Malignant respiratory tract neoplasm 10.98 9.56 5 242005 51 63246961
Cholecystitis chronic 10.98 9.56 14 241996 10347 63236665
Vein disorder 10.97 9.56 3 242007 5138 63241874
Device adhesion issue 10.97 9.56 3 242007 5138 63241874
Mood altered 10.95 9.56 25 241985 14718 63232294
Hypoglycaemia 10.93 9.56 162 241848 59903 63187109
Mononeuropathy multiplex 10.92 9.56 9 242001 283 63246729
Weight bearing difficulty 10.91 9.56 28 241982 2584 63244428
Mechanical ileus 10.91 9.56 12 241998 545 63246467
Chronic myeloid leukaemia 10.90 9.56 26 241984 2292 63244720
Stress ulcer 10.90 9.56 5 242005 52 63246960
Philadelphia positive acute lymphocytic leukaemia 10.89 9.56 4 242006 22 63246990
Thrombocytopenia neonatal 10.89 9.56 4 242006 22 63246990
Burkholderia pseudomallei infection 10.89 9.56 4 242006 22 63246990
Movement disorder 10.88 9.56 44 241966 21617 63225395
Skin laceration 10.86 9.56 47 241963 22661 63224351
Spinal fracture 10.86 9.56 112 241898 18159 63228853
Collagen disorder 10.85 9.56 8 242002 213 63246799
Parakeratosis 10.84 9.56 9 242001 286 63246726
Blood urine present 10.83 9.56 26 241984 15043 63231969
Retinal infiltrates 10.80 9.56 3 242007 5 63247007
Pancreatic leak 10.80 9.56 3 242007 5 63247007
Gastroenteritis bacterial 10.77 9.56 10 242000 370 63246642
Guillain-Barre syndrome 10.75 9.56 36 241974 3857 63243155
Antineutrophil cytoplasmic antibody 10.74 9.56 4 242006 23 63246989
Toxic skin eruption 10.74 9.56 85 241925 12800 63234212
Tachypnoea 10.73 9.56 107 241903 17195 63229817
Granuloma 10.73 9.56 47 241963 5714 63241298
Graft versus host disease in lung 10.72 9.56 10 242000 372 63246640
Abdominal wound dehiscence 10.72 9.56 8 242002 217 63246795
Retinal degeneration 10.70 9.56 15 241995 874 63246138
Disseminated aspergillosis 10.70 9.56 6 242004 98 63246914
Facial nerve disorder 10.70 9.56 12 241998 557 63246455
Pupillary disorder 10.69 9.56 8 242002 218 63246794
Streptococcal bacteraemia 10.69 9.56 22 241988 1755 63245257
Proteus infection 10.67 9.56 17 241993 1111 63245901
Temperature regulation disorder 10.66 9.56 5 242005 6127 63240885
Oesophageal ulcer haemorrhage 10.66 9.56 10 242000 375 63246637
Fulminant type 1 diabetes mellitus 10.66 9.56 11 241999 464 63246548
Infertility 10.65 9.56 14 241996 767 63246245
Nerve block 10.64 9.56 14 241996 768 63246244
Drug level increased 10.63 9.56 133 241877 22603 63224409
Insurance issue 10.63 9.56 5 242005 6116 63240896
Muscle atrophy 10.62 9.56 54 241956 6979 63240033
Essential hypertension 10.62 9.56 3 242007 5030 63241982
Anastomotic leak 10.62 9.56 11 241999 466 63246546
Palpitations 10.62 9.56 338 241672 112432 63134580
Exophthalmos 10.61 9.56 20 241990 1496 63245516
Henoch-Schonlein purpura nephritis 10.60 9.56 4 242006 24 63246988
Leukoerythroblastic anaemia 10.60 9.56 4 242006 24 63246988
Lymphadenitis bacterial 10.60 9.56 4 242006 24 63246988
Sense of oppression 10.57 9.56 16 241994 1000 63246012
Nail disorder 10.56 9.56 21 241989 12994 63234018
Aspartate aminotransferase abnormal 10.56 9.56 17 241993 1121 63245891
Umbilical cord vascular disorder 10.54 9.56 6 242004 101 63246911
Scar 10.54 9.56 23 241987 13759 63233253
Pneumonia legionella 10.50 9.56 21 241989 1641 63245371
Amylase increased 10.50 9.56 50 241960 6295 63240717
Blood albumin decreased 10.50 9.56 94 241916 14672 63232340
Oedematous pancreatitis 10.49 9.56 12 241998 569 63246443
Fasciitis 10.48 9.56 12 241998 570 63246442
Arthropod bite 10.45 9.56 9 242001 7969 63239043
Asplenia 10.45 9.56 3 242007 6 63247006
Emphysematous cholecystitis 10.45 9.56 3 242007 6 63247006
Injection site irritation 10.44 9.56 3 242007 4975 63242037
Chromosomal deletion 10.44 9.56 6 242004 103 63246909
Myelitis 10.44 9.56 19 241991 1384 63245628
Acidosis 10.43 9.56 76 241934 11157 63235855
Labelled drug-drug interaction medication error 10.42 9.56 87 241923 13312 63233700
Polymyalgia rheumatica 10.41 9.56 35 241975 3756 63243256
Prurigo 10.41 9.56 15 241995 897 63246115
Haemodialysis 10.39 9.56 64 241946 8883 63238129
Pneumonitis chemical 10.38 9.56 8 242002 228 63246784
Infusion site pruritus 10.37 9.56 5 242005 6030 63240982
Polymyositis 10.36 9.56 22 241988 1794 63245218
Dermatomyositis 10.35 9.56 29 241981 2819 63244193
Disseminated coccidioidomycosis 10.35 9.56 5 242005 59 63246953
Lipid metabolism disorder 10.35 9.56 5 242005 59 63246953
Therapy non-responder 10.34 9.56 370 241640 75531 63171481
Corneal graft rejection 10.33 9.56 4 242006 26 63246986
Rash maculo-papular 10.32 9.56 175 241835 31721 63215291
Renal cyst 10.32 9.56 71 241939 10231 63236781
Stillbirth 10.32 9.56 52 241958 6698 63240314
Chronic myeloid leukaemia recurrent 10.29 9.56 8 242002 231 63246781
Diverticulitis intestinal perforated 10.28 9.56 6 242004 106 63246906
Nightmare 10.27 9.56 38 241972 19156 63227856
Mycobacterial peritonitis 10.27 9.56 5 242005 60 63246952
Endocarditis enterococcal 10.27 9.56 5 242005 60 63246952
Acute hepatic failure 10.26 9.56 111 241899 18216 63228796
Bradyphrenia 10.26 9.56 7 242003 6973 63240039
Blepharospasm 10.26 9.56 5 242005 5991 63241021
Dysphagia 10.25 9.56 258 241752 88327 63158685
Steatorrhoea 10.21 9.56 11 241999 488 63246524
Corneal lesion 10.21 9.56 4 242006 27 63246985
Kidney congestion 10.21 9.56 4 242006 27 63246985
Lacrimal haemorrhage 10.21 9.56 4 242006 27 63246985
New onset diabetes after transplantation 10.19 9.56 6 242004 108 63246904
Acute lymphocytic leukaemia recurrent 10.19 9.56 25 241985 2244 63244768
Intestinal infarction 10.17 9.56 16 241994 1034 63245978
Vestibular neuronitis 10.16 9.56 12 241998 589 63246423
Pathological fracture 10.14 9.56 63 241947 8771 63238241
Malignant urinary tract neoplasm 10.14 9.56 3 242007 7 63247005
Small intestine gangrene 10.14 9.56 3 242007 7 63247005
Tubulointerstitial nephritis and uveitis syndrome 10.12 9.56 8 242002 237 63246775
Papilloma viral infection 10.12 9.56 20 241990 1550 63245462
Weaning failure 10.10 9.56 10 242000 401 63246611
Chorioretinitis 10.10 9.56 12 241998 593 63246419
Joint abscess 10.08 9.56 10 242000 402 63246610
Pseudomonas bronchitis 10.08 9.56 4 242006 28 63246984
Odontogenic cyst 10.08 9.56 4 242006 28 63246984
Soft tissue infection 10.08 9.56 24 241986 2113 63244899
Pouchitis 10.06 9.56 11 241999 496 63246516
Human herpesvirus 6 encephalitis 10.06 9.56 8 242002 239 63246773
Craniosynostosis 10.05 9.56 7 242003 170 63246842
Biliary tract disorder 10.03 9.56 14 241996 813 63246199
Impaired fasting glucose 10.00 9.56 8 242002 241 63246771
Acinetobacter infection 10.00 9.56 20 241990 1563 63245449
Musculoskeletal discomfort 9.99 9.56 35 241975 17932 63229080
Nosocomial infection 9.99 9.56 21 241989 1700 63245312
Body temperature increased 9.99 9.56 92 241918 37100 63209912
Anal sphincter atony 9.97 9.56 8 242002 242 63246770
Laparoscopic surgery 9.96 9.56 4 242006 29 63246983
Metastases to meninges 9.96 9.56 27 241983 2575 63244437
Pulse absent 9.95 9.56 4 242006 5370 63241642
Klebsiella sepsis 9.94 9.56 19 241991 1436 63245576
Affect lability 9.93 9.56 17 241993 11134 63235878
Bacterial endophthalmitis 9.90 9.56 6 242004 114 63246898
Post transplant distal limb syndrome 9.89 9.56 8 242002 245 63246767
Skin atrophy 9.89 9.56 41 241969 4865 63242147
Cerebral aspergillosis 9.88 9.56 10 242000 412 63246600
Arteriosclerosis 9.86 9.56 69 241941 9997 63237015
Aortic dissection rupture 9.85 9.56 3 242007 8 63247004
Transferrin increased 9.85 9.56 3 242007 8 63247004
Injection site calcification 9.85 9.56 4 242006 30 63246982
Kidney fibrosis 9.84 9.56 22 241988 1859 63245153
Idiopathic intracranial hypertension 9.84 9.56 29 241981 2902 63244110
Hyperparathyroidism secondary 9.83 9.56 19 241991 1448 63245564
Hypoperfusion 9.83 9.56 19 241991 1448 63245564
Extrapulmonary tuberculosis 9.83 9.56 9 242001 327 63246685
Cytokine storm 9.83 9.56 9 242001 327 63246685
CSF protein increased 9.82 9.56 11 241999 510 63246502
Vanishing bile duct syndrome 9.80 9.56 13 241997 719 63246293
Meningoencephalitis viral 9.78 9.56 9 242001 329 63246683
Portal vein thrombosis 9.78 9.56 27 241983 2603 63244409
Herpes simplex oesophagitis 9.77 9.56 7 242003 178 63246834
Rhodococcus infection 9.76 9.56 6 242004 117 63246895
Eye infection staphylococcal 9.76 9.56 6 242004 117 63246895
Visual impairment 9.76 9.56 246 241764 84200 63162812
Lentigo maligna 9.75 9.56 8 242002 250 63246762
Nasal discomfort 9.75 9.56 3 242007 4757 63242255
Impaired quality of life 9.74 9.56 24 241986 13759 63233253
Vaginitis gardnerella 9.74 9.56 4 242006 31 63246981
Vaginal haemorrhage 9.73 9.56 63 241947 27424 63219588
Gastroenteritis adenovirus 9.73 9.56 8 242002 251 63246761
Neoplasm recurrence 9.72 9.56 27 241983 2611 63244401
Neurological decompensation 9.72 9.56 27 241983 2611 63244401
Intraocular pressure decreased 9.72 9.56 6 242004 118 63246894
Osteitis 9.69 9.56 31 241979 3243 63243769
Thinking abnormal 9.68 9.56 16 241994 10627 63236385
Splenic infarction 9.68 9.56 21 241989 1738 63245274
Stomatococcal infection 9.68 9.56 6 242004 119 63246893
Arthrodesis 9.67 9.56 28 241982 2773 63244239
Intraocular lens implant 9.67 9.56 9 242001 334 63246678
Weight fluctuation 9.66 9.56 14 241996 9805 63237207
No adverse event 9.64 9.56 106 241904 41299 63205713
SARS-CoV-2 antibody test negative 9.64 9.56 7 242003 182 63246830
Gamma-glutamyltransferase 9.63 9.56 4 242006 32 63246980
Anti A antibody positive 9.63 9.56 4 242006 32 63246980
Blood corticotrophin decreased 9.63 9.56 9 242001 336 63246676
Cyst 9.61 9.56 25 241985 14074 63232938
Carotid artery aneurysm 9.60 9.56 9 242001 337 63246675
Dermatitis contact 9.60 9.56 17 241993 10991 63236021
Ovarian cyst 9.60 9.56 30 241980 15915 63231097
Myocardiac abscess 9.60 9.56 3 242007 9 63247003
Glutamate dehydrogenase level abnormal 9.60 9.56 3 242007 9 63247003
Pancreatitis viral 9.60 9.56 3 242007 9 63247003
Lower gastrointestinal perforation 9.60 9.56 3 242007 9 63247003
Agnosia 9.59 9.56 6 242004 121 63246891
Pathogen resistance 9.58 9.56 49 241961 6349 63240663
Cerebellar atrophy 9.58 9.56 13 241997 735 63246277
Cellulitis staphylococcal 9.58 9.56 13 241997 735 63246277
Antithrombin III decreased 9.57 9.56 8 242002 257 63246755
Device use error 9.56 9.56 5 242005 5756 63241256
Hemiparesis 9.56 9.56 133 241877 23149 63223863

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cytomegalovirus infection 1000.95 10.58 979 201661 25156 34729135
Pneumocystis jirovecii pneumonia 878.21 10.58 803 201837 18907 34735384
Drug abuse 456.61 10.58 30 202610 99066 34655225
Transplant rejection 447.31 10.58 414 202226 9897 34744394
Post transplant lymphoproliferative disorder 431.42 10.58 334 202306 6194 34748097
Completed suicide 418.29 10.58 42 202598 98126 34656165
Death 412.04 10.58 1079 201561 396970 34357321
Product dose omission issue 405.00 10.58 98 202542 119613 34634678
Product use in unapproved indication 394.37 10.58 1534 201106 115965 34638326
Hepatitis B 362.83 10.58 291 202349 5692 34748599
Nocardiosis 351.57 10.58 242 202398 3709 34750582
Fatigue 349.79 10.58 1050 201590 369603 34384688
Interstitial lung disease 342.38 10.58 991 201649 64291 34690000
Epstein-Barr virus infection 322.61 10.58 302 202338 7326 34746965
Bronchopulmonary aspergillosis 306.41 10.58 401 202239 14258 34740033
Strongyloidiasis 282.02 10.58 183 202457 2528 34751763
Polyomavirus-associated nephropathy 272.30 10.58 205 202435 3639 34750652
Osteonecrosis 268.27 10.58 379 202261 14511 34739780
Kidney transplant rejection 266.77 10.58 270 202370 7227 34747064
Nausea 252.80 10.58 1064 201576 338844 34415447
Hepatitis E 244.90 10.58 152 202488 1934 34752357
Complications of transplanted kidney 231.41 10.58 201 202439 4408 34749883
Aspergillus infection 229.83 10.58 318 202322 11936 34742355
Haemophagocytic lymphohistiocytosis 226.04 10.58 325 202315 12648 34741643
Pyrexia 225.07 10.58 2929 199711 330084 34424207
Hepatitis B reactivation 222.73 10.58 183 202457 3708 34750583
Diffuse large B-cell lymphoma 222.24 10.58 243 202397 7127 34747164
Asthenia 215.11 10.58 717 201923 244534 34509757
Transplant dysfunction 214.14 10.58 153 202487 2496 34751795
Lymphoproliferative disorder 210.82 10.58 154 202486 2605 34751686
Fall 209.81 10.58 549 202091 202336 34551955
Overdose 205.09 10.58 138 202502 90921 34663370
Anxiety 204.16 10.58 166 202474 99262 34655029
Hypotension 194.30 10.58 648 201992 221001 34533290
Steroid diabetes 194.24 10.58 134 202506 2061 34752230
Cytomegalovirus infection reactivation 192.55 10.58 190 202450 4928 34749363
Pulmonary nocardiosis 190.93 10.58 97 202543 811 34753480
Dizziness 190.08 10.58 641 201999 217880 34536411
Pain 189.41 10.58 584 202056 204091 34550200
Immunosuppressant drug level increased 177.99 10.58 197 202443 5858 34748433
Cytomegalovirus viraemia 177.05 10.58 217 202423 7213 34747078
Respiratory failure 176.29 10.58 1155 201485 107417 34646874
Renal impairment 175.04 10.58 1040 201600 93473 34660818
Disseminated intravascular coagulation 172.48 10.58 387 202253 21429 34732862
Hepatic function abnormal 170.91 10.58 606 202034 43757 34710534
Cryptococcosis 164.70 10.58 126 202514 2293 34751998
BK virus infection 164.05 10.58 184 202456 5554 34748737
Feeling abnormal 163.48 10.58 81 202559 63154 34691137
Epstein-Barr virus associated lymphoproliferative disorder 162.36 10.58 115 202525 1849 34752442
Off label use 159.90 10.58 3359 199281 416165 34338126
Cytomegalovirus colitis 159.48 10.58 131 202509 2653 34751638
Acquired gene mutation 157.21 10.58 98 202542 1257 34753034
Posterior reversible encephalopathy syndrome 148.59 10.58 232 202408 9722 34744569
Sepsis 147.20 10.58 1544 201096 165017 34589274
Transplant failure 147.03 10.58 139 202501 3414 34750877
Polyomavirus viraemia 145.38 10.58 82 202558 863 34753428
Cardiac failure congestive 144.09 10.58 162 202478 83108 34671183
Somnolence 142.34 10.58 267 202373 110849 34643442
Disease recurrence 140.42 10.58 354 202286 21136 34733155
Progressive multifocal leukoencephalopathy 136.70 10.58 221 202419 9543 34744748
Pulmonary tuberculosis 135.15 10.58 152 202488 4602 34749689
Hypogammaglobulinaemia 134.97 10.58 194 202446 7546 34746745
Toxicity to various agents 134.81 10.58 650 201990 199712 34554579
Adenovirus infection 132.54 10.58 158 202482 5099 34749192
Depression 131.83 10.58 225 202415 96873 34657418
Mucormycosis 131.12 10.58 167 202473 5775 34748516
Intentional overdose 130.55 10.58 45 202595 43629 34710662
Drug hypersensitivity 130.44 10.58 165 202475 80364 34673927
Injection site pain 127.78 10.58 34 202606 38971 34715320
Chorioretinopathy 127.09 10.58 89 202551 1404 34752887
Brain abscess 125.03 10.58 120 202520 3005 34751286
Phaeohyphomycosis 124.94 10.58 72 202568 792 34753499
Acute respiratory distress syndrome 124.39 10.58 382 202258 25587 34728704
Thrombotic microangiopathy 124.22 10.58 222 202418 10408 34743883
Cytomegalovirus test positive 123.95 10.58 132 202508 3754 34750537
Cushingoid 123.59 10.58 112 202528 2602 34751689
Blood pressure increased 119.74 10.58 204 202436 87898 34666393
Bradycardia 119.60 10.58 157 202483 75261 34679030
Myocardial infarction 119.45 10.58 335 202305 120750 34633541
Insomnia 115.96 10.58 270 202370 103637 34650654
Multiple organ dysfunction syndrome 114.88 10.58 799 201841 75767 34678524
Neutropenic sepsis 114.20 10.58 249 202391 13518 34740773
Peripheral swelling 112.73 10.58 168 202472 76373 34677918
Septic shock 111.55 10.58 756 201884 71078 34683213
Hospitalisation 110.64 10.58 100 202540 56802 34697489
Pneumonia cytomegaloviral 110.50 10.58 111 202529 2943 34751348
Pneumonia bacterial 110.42 10.58 225 202415 11647 34742644
Headache 109.71 10.58 697 201943 199938 34554353
Constipation 108.19 10.58 418 202222 136564 34617727
Cytomegalovirus chorioretinitis 107.62 10.58 118 202522 3471 34750820
Wrong technique in product usage process 105.97 10.58 38 202602 35948 34718343
Disseminated tuberculosis 104.36 10.58 93 202547 2112 34752179
Viraemia 103.52 10.58 73 202567 1165 34753126
General physical health deterioration 103.02 10.58 1167 201473 127102 34627189
Osteonecrosis of jaw 102.89 10.58 281 202359 17608 34736683
Graft versus host disease 102.71 10.58 204 202436 10365 34743926
Cerebrovascular accident 102.35 10.58 211 202429 84600 34669691
Agitation 102.21 10.58 109 202531 57290 34697001
Heart rate decreased 101.50 10.58 29 202611 31716 34722575
Blood pressure fluctuation 99.55 10.58 14 202626 25235 34729056
Confusional state 98.43 10.58 465 202175 143695 34610596
Pseudomonas infection 98.25 10.58 220 202420 12162 34742129
Intentional product misuse 97.54 10.58 73 202567 45538 34708753
Alveolar proteinosis 96.54 10.58 50 202590 437 34753854
Varicella zoster virus infection 95.21 10.58 81 202559 1725 34752566
Epstein-Barr virus infection reactivation 94.41 10.58 66 202574 1038 34753253
Arthralgia 93.28 10.58 590 202050 169451 34584840
Loss of personal independence in daily activities 92.77 10.58 38 202602 33141 34721150
Candida infection 91.84 10.58 268 202372 17447 34736844
Pneumothorax 91.57 10.58 281 202359 18811 34735480
Cytomegalovirus enterocolitis 91.07 10.58 62 202578 932 34753359
Lower respiratory tract infection 90.80 10.58 394 202246 31243 34723048
Herpes simplex 90.64 10.58 135 202505 5424 34748867
Inappropriate schedule of product administration 90.49 10.58 138 202502 62158 34692133
Leukopenia 89.06 10.58 647 201993 62209 34692082
Herpes zoster 88.69 10.58 415 202225 33984 34720307
Muscle abscess 87.88 10.58 51 202589 569 34753722
Atypical mycobacterial infection 87.33 10.58 58 202582 835 34753456
Infection reactivation 86.88 10.58 71 202569 1427 34752864
Mental status changes 86.65 10.58 57 202583 38026 34716265
Weight increased 84.78 10.58 267 202373 92766 34661525
Lymphopenia 84.56 10.58 247 202393 16088 34738203
Unevaluable event 83.82 10.58 42 202598 32548 34721743
Pneumomediastinum 83.75 10.58 85 202555 2282 34752009
Rebound effect 83.52 10.58 99 202541 3175 34751116
Electrocardiogram QT prolonged 83.21 10.58 69 202571 40883 34713408
Suicide attempt 83.13 10.58 63 202577 39053 34715238
Pneumatosis intestinalis 83.02 10.58 108 202532 3815 34750476
Chronic graft versus host disease 82.76 10.58 114 202526 4259 34750032
Blood lactate dehydrogenase increased 82.53 10.58 307 202333 22683 34731608
Hyperhidrosis 81.78 10.58 200 202440 75492 34678799
Pain in extremity 81.77 10.58 416 202224 126097 34628194
Stress 81.28 10.58 37 202603 30310 34723981
Weight decreased 80.94 10.58 644 201996 175657 34578634
Immunosuppression 80.61 10.58 137 202503 6167 34748124
Mycobacterial infection 79.92 10.58 83 202557 2291 34752000
Muscle spasms 79.61 10.58 200 202440 74801 34679490
Incorrect dose administered 78.99 10.58 71 202569 40444 34713847
Lung abscess 78.30 10.58 87 202553 2598 34751693
JC virus infection 77.59 10.58 79 202561 2129 34752162
Human herpesvirus 8 infection 75.80 10.58 55 202585 920 34753371
Nephropathy toxic 75.67 10.58 201 202439 12387 34741904
C-reactive protein increased 75.57 10.58 555 202085 53543 34700748
Osteoporosis 74.86 10.58 201 202439 12467 34741824
Disseminated cryptococcosis 74.78 10.58 63 202577 1323 34752968
Plasma cell myeloma 74.64 10.58 80 202560 41957 34712334
Dermoid cyst 74.36 10.58 31 202609 154 34754137
Neuroleptic malignant syndrome 72.96 10.58 9 202631 17925 34736366
Enterococcal infection 72.33 10.58 164 202476 9142 34745149
Blood glucose increased 72.30 10.58 176 202464 66542 34687749
Angiocentric lymphoma 72.15 10.58 35 202605 262 34754029
Sedation 71.32 10.58 17 202623 20989 34733302
Musculoskeletal stiffness 71.12 10.58 100 202540 46580 34707711
Escherichia infection 70.53 10.58 151 202489 8094 34746197
Gait disturbance 70.30 10.58 255 202385 84885 34669406
Mycobacterium abscessus infection 69.90 10.58 42 202598 502 34753789
Heart rate increased 69.89 10.58 100 202540 46243 34708048
Memory impairment 69.86 10.58 89 202551 43229 34711062
Pneumonia 69.73 10.58 2663 199977 359964 34394327
Abdominal discomfort 69.54 10.58 152 202488 59683 34694608
Tremor 69.08 10.58 246 202394 82341 34671950
Therapy partial responder 68.75 10.58 164 202476 9452 34744839
International normalised ratio increased 68.57 10.58 105 202535 47222 34707069
Hepatic failure 68.39 10.58 387 202253 34144 34720147
Blood pressure systolic increased 67.98 10.58 24 202616 22928 34731363
COVID-19 67.92 10.58 718 201922 76832 34677459
Acinetobacter infection 67.48 10.58 56 202584 1151 34753140
Amnesia 67.17 10.58 35 202605 26528 34727763
Dehydration 67.16 10.58 459 202181 129510 34624781
Back pain 67.03 10.58 422 202218 121367 34632924
Infection 66.65 10.58 813 201827 90102 34664189
Parvovirus B19 infection 65.95 10.58 48 202592 807 34753484
Immunosuppressant drug level decreased 65.61 10.58 56 202584 1198 34753093
Chronic allograft nephropathy 65.49 10.58 56 202584 1201 34753090
Meningitis cryptococcal 65.17 10.58 75 202565 2329 34751962
Trichophytosis 64.84 10.58 33 202607 277 34754014
Substance-induced psychotic disorder 64.41 10.58 64 202576 1674 34752617
Epstein Barr virus positive mucocutaneous ulcer 64.26 10.58 35 202605 342 34753949
Lymphocytic infiltration 64.09 10.58 44 202596 671 34753620
Mycetoma mycotic 63.93 10.58 24 202616 85 34754206
Obliterative bronchiolitis 63.62 10.58 55 202585 1198 34753093
Renal transplant failure 63.26 10.58 52 202588 1054 34753237
Visceral leishmaniasis 62.89 10.58 41 202599 571 34753720
Fungal infection 62.46 10.58 219 202421 15716 34738575
Upper respiratory tract inflammation 62.38 10.58 63 202577 1681 34752610
Diffuse large B-cell lymphoma recurrent 62.37 10.58 85 202555 3143 34751148
COVID-19 pneumonia 62.09 10.58 228 202412 16739 34737552
Drug resistance 61.92 10.58 306 202334 25621 34728670
Aggression 61.85 10.58 81 202559 38883 34715408
Suicidal ideation 61.05 10.58 87 202553 40301 34713990
Balance disorder 61.03 10.58 88 202552 40566 34713725
Full blood count decreased 60.71 10.58 15 202625 18073 34736218
Therapy interrupted 60.59 10.58 5 202635 13692 34740599
Liver disorder 59.64 10.58 361 202279 32636 34721655
Joint swelling 59.52 10.58 165 202475 59725 34694566
Febrile neutropenia 59.49 10.58 1119 201521 135730 34618561
Staphylococcal sepsis 58.98 10.58 157 202483 9687 34744604
Pancytopenia 58.49 10.58 824 201816 94333 34659958
Pruritus 58.23 10.58 534 202106 141447 34612844
Pneumocystis jirovecii infection 58.00 10.58 61 202579 1709 34752582
Organising pneumonia 57.60 10.58 115 202525 5864 34748427
Diabetes mellitus 57.18 10.58 466 202174 46407 34707884
Sinusitis 57.01 10.58 95 202545 41307 34712984
Acute graft versus host disease in skin 56.18 10.58 105 202535 5096 34749195
Dry skin 56.15 10.58 59 202581 31228 34723063
Bone marrow failure 56.06 10.58 325 202315 28928 34725363
Liver transplant rejection 55.59 10.58 65 202575 2054 34752237
Drug ineffective for unapproved indication 55.29 10.58 278 202362 23437 34730854
Drug intolerance 54.92 10.58 170 202470 59400 34694891
Pneumonia cryptococcal 54.87 10.58 44 202596 860 34753431
Sweat gland tumour 54.11 10.58 33 202607 406 34753885
Infective aneurysm 53.69 10.58 37 202603 568 34753723
Cardio-respiratory arrest 52.20 10.58 156 202484 55117 34699174
Cytomegalovirus enteritis 52.18 10.58 34 202606 473 34753818
Foetal growth restriction 52.02 10.58 89 202551 4028 34750263
Subcutaneous emphysema 51.88 10.58 48 202592 1146 34753145
Product quality issue 51.86 10.58 17 202623 17018 34737273
Delayed graft function 51.51 10.58 64 202576 2157 34752134
Systemic mycosis 51.17 10.58 54 202586 1519 34752772
Thrombosis 50.89 10.58 138 202502 50320 34703971
Heart transplant rejection 50.63 10.58 48 202592 1183 34753108
Unresponsive to stimuli 50.59 10.58 51 202589 27518 34726773
Fungal endocarditis 50.55 10.58 30 202610 350 34753941
Low birth weight baby 50.36 10.58 129 202511 7776 34746515
Drug withdrawal syndrome 50.34 10.58 26 202614 19808 34734483
Lymphocele 50.34 10.58 50 202590 1307 34752984
Intensive care unit acquired weakness 49.97 10.58 44 202596 983 34753308
Pyoderma gangrenosum 49.92 10.58 51 202589 1380 34752911
Vomiting 49.92 10.58 1075 201565 246546 34507745
Full blood count abnormal 49.62 10.58 23 202617 18645 34735646
Seizure 49.47 10.58 380 202260 104477 34649814
Scleroderma renal crisis 49.46 10.58 26 202614 235 34754056
Myelosuppression 49.34 10.58 232 202408 19033 34735258
Paraesthesia 49.21 10.58 198 202442 63974 34690317
Tubulointerstitial nephritis 48.69 10.58 246 202394 20778 34733513
Tuberculosis 48.59 10.58 134 202506 8443 34745848
Squamous cell carcinoma of skin 48.36 10.58 156 202484 10725 34743566
B-cell lymphoma 48.28 10.58 89 202551 4274 34750017
Adrenal insufficiency 48.27 10.58 185 202455 13862 34740429
Syncope 48.20 10.58 321 202319 91130 34663161
Pleurisy 48.14 10.58 93 202547 4628 34749663
Arthropathy 47.99 10.58 51 202589 26856 34727435
Tumour lysis syndrome 47.83 10.58 211 202429 16848 34737443
Epistaxis 47.71 10.58 175 202465 58076 34696215
Cutaneous nocardiosis 47.69 10.58 22 202618 145 34754146
Drug ineffective 47.66 10.58 3162 199478 453589 34300702
Encephalitis 47.65 10.58 120 202520 7157 34747134
Therapeutic product effect decreased 47.58 10.58 80 202560 34663 34719628
Pneumonia fungal 47.46 10.58 118 202522 6982 34747309
Cytomegalovirus oesophagitis 47.40 10.58 32 202608 474 34753817
Amoebic colitis 47.16 10.58 19 202621 85 34754206
Large intestinal ulcer 46.09 10.58 57 202583 1912 34752379
Coma 46.01 10.58 125 202515 45553 34708738
Adverse drug reaction 45.55 10.58 62 202578 29280 34725011
Rash 45.47 10.58 965 201675 221787 34532504
Nephrotic syndrome 45.31 10.58 118 202522 7185 34747106
Systemic infection 45.21 10.58 96 202544 5116 34749175
Diarrhoea 45.15 10.58 1826 200814 388086 34366205
Systemic candida 45.05 10.58 79 202561 3647 34750644
Injection site erythema 44.78 10.58 18 202622 15881 34738410
Blood beta-D-glucan increased 44.72 10.58 29 202611 400 34753891
Cardiogenic shock 44.69 10.58 53 202587 26565 34727726
Staphylococcal infection 44.54 10.58 334 202306 32426 34721865
Abdominal distension 44.52 10.58 181 202459 58311 34695980
Acute graft versus host disease 44.44 10.58 109 202531 6394 34747897
Migraine 44.23 10.58 23 202617 17455 34736836
Accidental exposure to product 44.18 10.58 10 202630 12792 34741499
Cardiac arrest 44.18 10.58 351 202289 95808 34658483
Oesophageal candidiasis 44.10 10.58 86 202554 4310 34749981
Presyncope 44.07 10.58 28 202612 19031 34735260
Proteinuria 43.78 10.58 219 202421 18423 34735868
Cytomegalovirus gastrointestinal infection 43.74 10.58 23 202617 208 34754083
Epstein-Barr virus associated lymphoma 43.74 10.58 34 202606 634 34753657
Gastrooesophageal reflux disease 43.51 10.58 97 202543 37827 34716464
Bacterial infection 43.34 10.58 205 202435 16858 34737433
Poisoning 43.31 10.58 9 202631 12217 34742074
Kaposi's sarcoma 43.30 10.58 38 202602 845 34753446
Varicella 43.26 10.58 51 202589 1626 34752665
Intentional self-injury 43.25 10.58 13 202627 13758 34740533
Dyspepsia 42.93 10.58 93 202547 36639 34717652
Respiratory arrest 42.78 10.58 60 202580 27983 34726308
Dry mouth 42.67 10.58 68 202572 30097 34724194
Hallucination 42.64 10.58 154 202486 51344 34702947
Loss of consciousness 42.64 10.58 292 202348 82375 34671916
Peritonitis 42.58 10.58 198 202442 16167 34738124
Varicella zoster pneumonia 42.21 10.58 17 202623 76 34754215
Intestinal perforation 42.19 10.58 132 202508 8928 34745363
Basal cell carcinoma 42.05 10.58 225 202415 19433 34734858
Therapy cessation 41.98 10.58 23 202617 16950 34737341
Mycobacterium chelonae infection 41.84 10.58 36 202604 779 34753512
Infectious pleural effusion 41.73 10.58 61 202579 2409 34751882
Small intestinal perforation 41.69 10.58 57 202583 2114 34752177
Serotonin syndrome 41.21 10.58 33 202607 19900 34734391
Lung consolidation 41.10 10.58 100 202540 5836 34748455
Cerebral aspergillosis 41.07 10.58 46 202594 1386 34752905
Chest pain 40.92 10.58 504 202136 126258 34628033
Subcutaneous abscess 40.78 10.58 77 202563 3766 34750525
Pneumonia adenoviral 40.57 10.58 26 202614 351 34753940
Human herpesvirus 6 infection 40.51 10.58 55 202585 2026 34752265
Gastrointestinal perforation 40.50 10.58 77 202563 3786 34750505
Gastric disorder 40.44 10.58 11 202629 12430 34741861
Bacterial sepsis 40.22 10.58 92 202548 5158 34749133
Colitis ulcerative 40.17 10.58 196 202444 16324 34737967
Listeria sepsis 40.11 10.58 20 202620 160 34754131
Peripheral T-cell lymphoma unspecified stage IV 39.90 10.58 13 202627 26 34754265
Peripheral T-cell lymphoma unspecified 39.75 10.58 28 202612 446 34753845
Large intestine perforation 39.70 10.58 124 202516 8379 34745912
Device issue 39.54 10.58 5 202635 9772 34744519
Injection site haemorrhage 39.50 10.58 5 202635 9763 34744528
Contusion 39.32 10.58 96 202544 36268 34718023
Necrotising retinitis 38.83 10.58 35 202605 807 34753484
Focal segmental glomerulosclerosis 38.64 10.58 53 202587 1972 34752319
Human polyomavirus infection 38.47 10.58 33 202607 711 34753580
Hypersomnia 38.44 10.58 12 202628 12395 34741896
Atypical femur fracture 38.35 10.58 24 202616 310 34753981
Miosis 38.27 10.58 5 202635 9530 34744761
Retinal drusen 38.16 10.58 11 202629 11 34754280
Sleep disorder 38.06 10.58 79 202561 31609 34722682
Neutropenia 37.65 10.58 1182 201458 155596 34598695
Concomitant disease aggravated 37.32 10.58 94 202546 5607 34748684
Toxoplasmosis 37.27 10.58 42 202598 1274 34753017
Dermatophytosis 37.23 10.58 21 202619 221 34754070
Graft versus host disease in skin 37.22 10.58 75 202565 3850 34750441
Oesophageal perforation 36.96 10.58 40 202600 1159 34753132
Steroid withdrawal syndrome 36.91 10.58 21 202619 225 34754066
Autoimmune neutropenia 36.90 10.58 22 202618 259 34754032
Hypoaesthesia 36.89 10.58 207 202433 61237 34693054
Cytomegalovirus gastritis 36.67 10.58 21 202619 228 34754063
Lactic acidosis 36.66 10.58 93 202547 34679 34719612
Myelodysplastic syndrome 36.53 10.58 213 202427 18995 34735296
Head injury 36.39 10.58 31 202609 18129 34736162
Osteoporotic fracture 36.35 10.58 38 202602 1057 34753234
Body temperature decreased 36.31 10.58 15 202625 13019 34741272
Plasmablastic lymphoma 36.28 10.58 24 202616 343 34753948
Mycoplasma infection 36.15 10.58 25 202615 386 34753905
Pseudomembranous colitis 36.14 10.58 61 202579 2730 34751561
Orthostatic hypotension 36.12 10.58 59 202581 25860 34728431
Actinic keratosis 36.06 10.58 81 202559 4486 34749805
Glucose tolerance impaired 36.06 10.58 67 202573 3237 34751054
Injection site swelling 35.98 10.58 11 202629 11516 34742775
Intestinal tuberculosis 35.88 10.58 17 202623 120 34754171
Hyperglycaemia 35.70 10.58 368 202272 39112 34715179
Myopathy 35.55 10.58 147 202493 11407 34742884
Gallbladder rupture 35.40 10.58 29 202611 585 34753706
Neck pain 35.05 10.58 58 202582 25291 34729000
Trichophytic granuloma 34.85 10.58 13 202627 45 34754246
Ileal ulcer 34.74 10.58 29 202611 601 34753690
Road traffic accident 34.70 10.58 30 202610 17420 34736871
Nasal congestion 34.51 10.58 50 202590 23007 34731284
Device malfunction 34.28 10.58 9 202631 10412 34743879
Alternaria infection 34.25 10.58 24 202616 379 34753912
Endocarditis 34.22 10.58 99 202541 6412 34747879
Cerebral venous thrombosis 34.10 10.58 31 202609 723 34753568
Flushing 33.95 10.58 87 202553 32333 34721958
Cytomegalovirus gastrointestinal ulcer 33.95 10.58 12 202628 34 34754257
Keratitis bacterial 33.84 10.58 14 202626 68 34754223
Psoriasis 33.52 10.58 114 202526 38698 34715593
Lung infiltration 33.47 10.58 156 202484 12749 34741542
Cystitis haemorrhagic 33.44 10.58 90 202550 5589 34748702
Tendon rupture 33.43 10.58 103 202537 6909 34747382
Growth retardation 33.22 10.58 47 202593 1801 34752490
Fractional exhaled nitric oxide increased 33.18 10.58 36 202604 1046 34753245
Akathisia 33.16 10.58 4 202636 8105 34746186
Rhabdomyolysis 33.09 10.58 245 202395 67918 34686373
Cytomegalovirus gastroenteritis 33.05 10.58 19 202621 208 34754083
Agranulocytosis 33.02 10.58 244 202396 23577 34730714
Nervousness 32.78 10.58 16 202624 12590 34741701
Prostatic specific antigen increased 32.76 10.58 170 202470 14510 34739781
Pleural effusion 32.41 10.58 658 201982 80888 34673403
Keratitis 32.36 10.58 41 202599 1410 34752881
Blood pressure decreased 32.33 10.58 171 202469 51344 34702947
Nasopharyngitis 32.31 10.58 255 202385 69713 34684578
Enterococcal sepsis 32.26 10.58 44 202596 1628 34752663
Therapy non-responder 32.19 10.58 358 202282 38788 34715503
Eye infection toxoplasmal 31.92 10.58 19 202621 223 34754068
Dysgeusia 31.87 10.58 66 202574 26431 34727860
Pulmonary alveolar haemorrhage 31.86 10.58 106 202534 7406 34746885
Diffuse large B-cell lymphoma refractory 31.83 10.58 38 202602 1228 34753063
Accidental overdose 31.82 10.58 42 202598 20098 34734193
C-reactive protein abnormal 31.72 10.58 6 202634 8704 34745587
Hepatitis fulminant 31.63 10.58 73 202567 4117 34750174
Klebsiella infection 31.51 10.58 115 202525 8416 34745875
Soft tissue mass 31.42 10.58 34 202606 985 34753306
Enterobacter infection 31.32 10.58 53 202587 2377 34751914
Hepatic cytolysis 31.24 10.58 23 202617 14473 34739818
Blood glucose decreased 31.22 10.58 19 202621 13218 34741073
Angiosarcoma 31.21 10.58 20 202620 270 34754021
Illness 31.11 10.58 20 202620 13509 34740782
Diarrhoea haemorrhagic 30.99 10.58 98 202542 6666 34747625
Disease progression 30.91 10.58 833 201807 107244 34647047
Endophthalmitis 30.87 10.58 65 202575 3443 34750848
Epstein-Barr virus test positive 30.82 10.58 26 202614 547 34753744
Ureteric stenosis 30.73 10.58 36 202604 1140 34753151
Gastritis bacterial 30.70 10.58 18 202622 205 34754086
Renal tubular injury 30.66 10.58 33 202607 950 34753341
Influenza like illness 30.63 10.58 72 202568 27562 34726729
Pulmonary fibrosis 30.57 10.58 197 202443 18199 34736092
Medication error 30.48 10.58 64 202576 25501 34728790
Tuberculous pleurisy 30.42 10.58 22 202618 366 34753925
Dyskinesia 30.32 10.58 52 202588 22361 34731930
Incorrect route of product administration 30.16 10.58 25 202615 14820 34739471
Multimorbidity 30.04 10.58 32 202608 910 34753381
Rhinorrhoea 29.98 10.58 65 202575 25603 34728688
Adenoviral hepatitis 29.91 10.58 25 202615 519 34753772
Respiratory depression 29.86 10.58 30 202610 16215 34738076
Injury 29.86 10.58 46 202594 20641 34733650
Viral load increased 29.81 10.58 53 202587 2474 34751817
Laboratory test abnormal 29.76 10.58 45 202595 20346 34733945
Gamma-glutamyltransferase increased 29.61 10.58 279 202361 28952 34725339
Ocular procedural complication 29.56 10.58 12 202628 55 34754236
H1N1 influenza 29.49 10.58 32 202608 930 34753361
Fungal skin infection 29.48 10.58 54 202586 2580 34751711
Central nervous system lymphoma 29.44 10.58 33 202607 995 34753296
Disseminated varicella zoster virus infection 29.36 10.58 20 202620 301 34753990
Cerebral infarction 29.30 10.58 265 202375 27190 34727101
Heart rate irregular 29.28 10.58 29 202611 15778 34738513
Pneumothorax spontaneous 29.23 10.58 26 202614 589 34753702
Gastroenteritis norovirus 29.21 10.58 40 202600 1486 34752805
Myositis 29.20 10.58 143 202497 11927 34742364
Arthritis bacterial 29.15 10.58 80 202560 5026 34749265
Urosepsis 29.10 10.58 149 202491 12650 34741641
Nephrolithiasis 29.07 10.58 85 202555 30248 34724043
Lung transplant rejection 29.05 10.58 29 202611 763 34753528
Hypofibrinogenaemia 29.01 10.58 42 202598 1644 34752647
Hepatitis infectious mononucleosis 28.87 10.58 11 202629 41 34754250
Mononeuropathy multiplex 28.82 10.58 17 202623 196 34754095
Oxygen saturation decreased 28.79 10.58 188 202452 53630 34700661
Ageusia 28.50 10.58 12 202628 10296 34743995
Enterovesical fistula 28.47 10.58 29 202611 782 34753509
Rash pruritic 28.44 10.58 72 202568 26869 34727422
Symptom masked 28.44 10.58 26 202614 611 34753680
Cardiac disorder 28.28 10.58 141 202499 42985 34711306
Chromoblastomycosis 28.27 10.58 11 202629 44 34754247
Haematocrit decreased 28.24 10.58 94 202546 32122 34722169
Infective spondylitis 28.21 10.58 18 202622 241 34754050
Throat irritation 28.19 10.58 13 202627 10572 34743719
Graft loss 28.17 10.58 30 202610 853 34753438
Opportunistic infection 28.09 10.58 41 202599 1617 34752674
Corneal deposits 28.02 10.58 17 202623 207 34754084
Lymphoma 28.02 10.58 145 202495 12362 34741929
Blood pressure diastolic decreased 27.81 10.58 9 202631 9085 34745206
Erectile dysfunction 27.81 10.58 48 202592 20589 34733702
Injection site mass 27.76 10.58 3 202637 6623 34747668
Haemorrhage subcutaneous 27.75 10.58 49 202591 2275 34752016
Premature baby 27.73 10.58 202 202438 19431 34734860
Glomerulonephritis membranoproliferative 27.69 10.58 22 202618 424 34753867
Psoriatic arthropathy 27.65 10.58 45 202595 19753 34734538
Urticaria 27.57 10.58 230 202410 62147 34692144
Injection site bruising 27.53 10.58 8 202632 8655 34745636
Endocarditis bacterial 27.42 10.58 31 202609 944 34753347
Infection in an immunocompromised host 27.35 10.58 26 202614 643 34753648
Hypoalbuminaemia 27.18 10.58 141 202499 12033 34742258
Haemoglobin decreased 27.05 10.58 515 202125 120257 34634034
Underdose 27.03 10.58 24 202616 13756 34740535
Lymphadenopathy 27.02 10.58 268 202372 28195 34726096
Product administration error 26.95 10.58 33 202607 16311 34737980
Cutaneous tuberculosis 26.95 10.58 13 202627 96 34754195
Condition aggravated 26.90 10.58 1367 201273 190829 34563462
Herpes zoster meningoencephalitis 26.90 10.58 19 202621 304 34753987
Myasthenia gravis crisis 26.85 10.58 25 202615 602 34753689
Skin striae 26.85 10.58 25 202615 602 34753689
Malacoplakia gastrointestinal 26.83 10.58 13 202627 97 34754194
Chronic inflammatory demyelinating polyradiculoneuropathy 26.81 10.58 27 202613 718 34753573
Immune reconstitution inflammatory syndrome 26.60 10.58 111 202529 8648 34745643
Ecthyma 26.60 10.58 22 202618 450 34753841
Blood creatine phosphokinase increased 26.45 10.58 152 202488 44705 34709586
Scedosporium infection 26.45 10.58 29 202611 853 34753438
Tonsillitis 26.38 10.58 49 202591 2367 34751924
T-cell lymphoma stage IV 26.31 10.58 14 202626 130 34754161
B-lymphocyte count decreased 26.31 10.58 25 202615 618 34753673
Renal graft infection 26.30 10.58 18 202622 273 34754018
Mycobacterium avium complex infection 26.26 10.58 50 202590 2461 34751830
Emotional distress 26.22 10.58 29 202611 14997 34739294
Microsporidia infection 26.17 10.58 26 202614 680 34753611
Drug dependence 26.13 10.58 64 202576 24153 34730138
Corneal lesion 26.12 10.58 9 202631 23 34754268
Sexual dysfunction 26.04 10.58 3 202637 6300 34747991
Respiratory alkalosis 25.74 10.58 40 202600 1669 34752622
Poikiloderma 25.72 10.58 15 202625 169 34754122
Pneumoperitoneum 25.71 10.58 41 202599 1749 34752542
Pyelonephritis chronic 25.70 10.58 10 202630 40 34754251
Salivary hypersecretion 25.66 10.58 9 202631 8635 34745656
Polyomavirus test positive 25.56 10.58 13 202627 109 34754182
Amoebiasis 25.55 10.58 11 202629 60 34754231
Burning sensation 25.51 10.58 42 202598 18352 34735939
Hepatosplenomegaly 25.49 10.58 67 202573 4102 34750189
Psoas abscess 25.43 10.58 24 202616 588 34753703
Pyelonephritis acute 25.34 10.58 44 202596 2015 34752276
Needle issue 25.31 10.58 3 202637 6162 34748129
Mantle cell lymphoma refractory 25.29 10.58 12 202628 85 34754206
Liver abscess 25.26 10.58 64 202576 3831 34750460
Acute kidney injury 25.23 10.58 1479 201161 303509 34450782
Gingival hypertrophy 25.19 10.58 41 202599 1780 34752511
Cryptococcal cutaneous infection 25.17 10.58 12 202628 86 34754205
Septic pulmonary embolism 25.14 10.58 10 202630 43 34754248
Perinephric abscess 25.14 10.58 10 202630 43 34754248
Exposed bone in jaw 25.12 10.58 38 202602 1548 34752743
Therapeutic response shortened 25.12 10.58 6 202634 7398 34746893
Bone tuberculosis 25.11 10.58 20 202620 387 34753904
Retinal pigment epitheliopathy 25.09 10.58 16 202624 214 34754077
Oropharyngeal pain 25.03 10.58 113 202527 35372 34718919
Sleep apnoea syndrome 24.96 10.58 50 202590 20271 34734020
West Nile viral infection 24.94 10.58 26 202614 721 34753570
Acute hepatic failure 24.80 10.58 153 202487 13921 34740370
Cholangitis 24.76 10.58 108 202532 8581 34745710
Discomfort 24.66 10.58 45 202595 18893 34735398
Cutaneous T-cell lymphoma 24.57 10.58 37 202603 1501 34752790
Ventricular fibrillation 24.50 10.58 61 202579 22893 34731398
Subdural haematoma 24.44 10.58 51 202589 20370 34733921
Factitious disorder 24.43 10.58 10 202630 47 34754244
Hypersensitivity 24.36 10.58 231 202409 60804 34693487
Meningoencephalitis herpetic 24.25 10.58 27 202613 808 34753483
Escherichia sepsis 24.22 10.58 71 202569 4633 34749658
Inflammatory marker increased 24.10 10.58 74 202566 4954 34749337
Splenic abscess 24.06 10.58 19 202621 363 34753928
Extranodal marginal zone B-cell lymphoma (MALT type) 24.02 10.58 15 202625 193 34754098
Pneumonitis 23.95 10.58 301 202339 33577 34720714
Molluscum contagiosum 23.91 10.58 17 202623 275 34754016
Papilloma viral infection 23.78 10.58 21 202619 471 34753820
Retinal detachment 23.69 10.58 77 202563 5314 34748977
Chest discomfort 23.68 10.58 202 202438 54328 34699963
Ejection fraction decreased 23.64 10.58 47 202593 19107 34735184
Pneumonia viral 23.63 10.58 55 202585 3119 34751172
Neuropathy peripheral 23.59 10.58 340 202300 82923 34671368
Adverse event 23.57 10.58 46 202594 18831 34735460
Acute myeloid leukaemia 23.56 10.58 184 202456 18086 34736205
Epstein-Barr virus antibody positive 23.45 10.58 17 202623 284 34754007
Gastroenteritis adenovirus 23.44 10.58 13 202627 132 34754159
Extrapyramidal disorder 23.43 10.58 24 202616 12856 34741435
Obesity 23.42 10.58 24 202616 12854 34741437
Vision blurred 23.37 10.58 163 202477 45800 34708491
Back disorder 23.34 10.58 5 202635 6646 34747645
Haemolytic uraemic syndrome 23.27 10.58 45 202595 2241 34752050
Parvovirus infection 23.23 10.58 20 202620 433 34753858
Second primary malignancy 23.22 10.58 99 202541 7787 34746504
Pyelonephritis 23.14 10.58 84 202556 6131 34748160
Irritability 23.07 10.58 70 202570 24620 34729671
Cataract subcapsular 23.04 10.58 19 202621 387 34753904
Hypoglycaemia 23.02 10.58 204 202436 54436 34699855
Pouchitis 22.98 10.58 24 202616 667 34753624
Meningoencephalitis viral 22.87 10.58 13 202627 139 34754152
Intraocular pressure increased 22.86 10.58 76 202564 5307 34748984
Kidney fibrosis 22.85 10.58 44 202596 2184 34752107
Hospice care 22.82 10.58 6 202634 6934 34747357
Gallbladder disorder 22.80 10.58 5 202635 6537 34747754
Adult T-cell lymphoma/leukaemia 22.79 10.58 13 202627 140 34754151
Granuloma 22.76 10.58 55 202585 3196 34751095
Erosive duodenitis 22.75 10.58 38 202602 1686 34752605
Glomerulonephritis 22.71 10.58 41 202599 1937 34752354
Syringe issue 22.66 10.58 3 202637 5661 34748630
Retinal haemorrhage 22.65 10.58 73 202567 5016 34749275
Peliosis hepatis 22.59 10.58 10 202630 59 34754232
Hydronephrosis 22.52 10.58 119 202521 10227 34744064
Pancreas transplant rejection 22.43 10.58 14 202626 180 34754111
Atypical pneumonia 22.41 10.58 56 202584 3324 34750967
Neisseria infection 22.39 10.58 9 202631 40 34754251
Sinusitis aspergillus 22.38 10.58 11 202629 85 34754206
Ear infection 22.35 10.58 16 202624 10215 34744076
Sinus congestion 22.35 10.58 3 202637 5602 34748689
Xanthogranuloma 22.32 10.58 10 202630 61 34754230
Inferior vena cava stenosis 22.30 10.58 8 202632 24 34754267
Cutaneous malacoplakia 22.27 10.58 11 202629 86 34754205
Hernia 22.26 10.58 14 202626 9569 34744722
Postoperative wound infection 22.18 10.58 70 202570 4756 34749535
Intervertebral disc degeneration 22.17 10.58 5 202635 6412 34747879
Bone abscess 22.17 10.58 14 202626 184 34754107
Hypervolaemia 22.13 10.58 51 202589 19658 34734633
Fear 22.09 10.58 17 202623 10459 34743832
Cerebral venous sinus thrombosis 22.07 10.58 21 202619 520 34753771
Vasculitis 21.96 10.58 126 202514 11170 34743121
Hyperplasia 21.94 10.58 22 202618 582 34753709
T-cell lymphoma 21.87 10.58 28 202612 973 34753318
Labelled drug-drug interaction medication error 21.84 10.58 155 202485 14784 34739507
Trichosporon infection 21.78 10.58 24 202616 710 34753581
Nightmare 21.74 10.58 31 202609 14360 34739931
Ureteric obstruction 21.73 10.58 31 202609 1197 34753094
Alanine aminotransferase increased 21.72 10.58 618 202022 80197 34674094
B-cell lymphoma recurrent 21.66 10.58 25 202615 779 34753512
Seasonal allergy 21.51 10.58 6 202634 6669 34747622
Lumbar vertebral fracture 21.49 10.58 44 202596 2285 34752006
Spinal compression fracture 21.47 10.58 90 202550 7026 34747265
Sphincter of Oddi dysfunction 21.46 10.58 12 202628 124 34754167
Herpes simplex test positive 21.41 10.58 14 202626 196 34754095
Coronary artery disease 21.40 10.58 178 202462 48127 34706164
Pustular psoriasis 21.36 10.58 36 202604 1609 34752682
Acute graft versus host disease in intestine 21.35 10.58 48 202592 2660 34751631
Appendicitis 21.30 10.58 33 202607 14774 34739517
Impaired healing 21.21 10.58 157 202483 15177 34739114
Listeriosis 21.07 10.58 28 202612 1010 34753281
Dehiscence 21.06 10.58 11 202629 98 34754193
Feeling hot 21.05 10.58 51 202589 19321 34734970
Squamous cell carcinoma 21.02 10.58 126 202514 11349 34742942
Gastroenteritis sapovirus 20.98 10.58 12 202628 130 34754161
Dengue fever 20.98 10.58 15 202625 245 34754046
Genitourinary tract infection 20.96 10.58 11 202629 99 34754192
Necrotising scleritis 20.94 10.58 10 202630 72 34754219
Pyelonephritis fungal 20.94 10.58 10 202630 72 34754219
Complications of transplanted lung 20.93 10.58 14 202626 204 34754087
Oral candidiasis 20.93 10.58 131 202509 11979 34742312
Polyneuropathy 20.88 10.58 153 202487 14743 34739548
Infertility 20.88 10.58 14 202626 205 34754086
Skin necrosis 20.86 10.58 78 202562 5775 34748516
Glomerulonephritis membranous 20.86 10.58 30 202610 1167 34753124
Apoptosis 20.78 10.58 18 202622 393 34753898
Polyglandular autoimmune syndrome type III 20.78 10.58 5 202635 0 34754291
Guillain-Barre syndrome 20.78 10.58 80 202560 6007 34748284
Candida sepsis 20.76 10.58 31 202609 1248 34753043
Pyomyositis 20.76 10.58 14 202626 207 34754084
Gait inability 20.75 10.58 57 202583 20701 34733590
Hyperglycaemic hyperosmolar nonketotic syndrome 20.75 10.58 31 202609 1249 34753042
Ocular hypertension 20.67 10.58 25 202615 819 34753472
Adenoviral haemorrhagic cystitis 20.67 10.58 18 202622 396 34753895
Mycobacterium fortuitum infection 20.64 10.58 13 202627 170 34754121
Hepatic atrophy 20.64 10.58 13 202627 170 34754121
Cerebral salt-wasting syndrome 20.63 10.58 9 202631 51 34754240
Myelitis 20.60 10.58 25 202615 822 34753469
Pathogen resistance 20.60 10.58 109 202531 9373 34744918
Abdominal pain upper 20.57 10.58 291 202349 71199 34683092
Papillary renal cell carcinoma 20.57 10.58 15 202625 253 34754038
Pollakiuria 20.44 10.58 53 202587 19621 34734670
Cystitis escherichia 20.38 10.58 13 202627 174 34754117
Lymphoplasmacytoid lymphoma/immunocytoma 20.37 10.58 8 202632 33 34754258
Pneumonia pneumococcal 20.34 10.58 41 202599 2105 34752186
Graft versus host disease in gastrointestinal tract 20.33 10.58 57 202583 3626 34750665
Neuroendocrine carcinoma of the skin 20.31 10.58 24 202616 767 34753524
Pulmonary cavitation 20.30 10.58 26 202614 904 34753387
Encephalitis Japanese B 20.29 10.58 7 202633 18 34754273
Superior sagittal sinus thrombosis 20.27 10.58 15 202625 259 34754032
Meningitis 20.20 10.58 68 202572 4779 34749512
Fusarium infection 20.11 10.58 29 202611 1131 34753160
Product storage error 20.09 10.58 11 202629 8111 34746180
Acute graft versus host disease in liver 19.98 10.58 34 202606 1532 34752759
Isosporiasis 19.90 10.58 11 202629 111 34754180
Renal tubular atrophy 19.88 10.58 29 202611 1143 34753148
Gastric ulcer 19.84 10.58 157 202483 15493 34738798
Muscle rigidity 19.82 10.58 19 202621 10499 34743792
Dermatophytosis of nail 19.81 10.58 9 202631 57 34754234
Empyema 19.78 10.58 52 202588 3184 34751107
Injection site reaction 19.76 10.58 28 202612 13005 34741286
Renal adenoma 19.76 10.58 7 202633 20 34754271
Renal abscess 19.74 10.58 15 202625 270 34754021
Throat tightness 19.71 10.58 12 202628 8346 34745945
Intervertebral discitis 19.70 10.58 41 202599 2154 34752137
Cytomegalovirus duodenitis 19.68 10.58 9 202631 58 34754233
IgA nephropathy 19.63 10.58 30 202610 1233 34753058
Gallbladder oedema 19.61 10.58 14 202626 228 34754063
Vitritis 19.59 10.58 25 202615 866 34753425
Meningitis listeria 19.56 10.58 19 202621 483 34753808
Complications of transplanted liver 19.56 10.58 14 202626 229 34754062
Sinus bradycardia 19.51 10.58 28 202612 12935 34741356
Scleritis 19.49 10.58 20 202620 544 34753747
Lepromatous leprosy 19.42 10.58 9 202631 60 34754231
Metastases to lymph nodes 19.41 10.58 66 202574 4662 34749629
Chronic graft versus host disease in skin 19.35 10.58 26 202614 948 34753343
Glomerulosclerosis 19.31 10.58 24 202616 809 34753482
Moraxella infection 19.30 10.58 14 202626 234 34754057
Histoplasmosis disseminated 19.28 10.58 31 202609 1332 34752959
Restrictive allograft syndrome 19.27 10.58 7 202633 22 34754269
Atrial fibrillation 19.25 10.58 551 202089 121842 34632449
Cytomegalovirus nephritis 19.24 10.58 11 202629 119 34754172
Prescribed overdose 19.19 10.58 20 202620 10627 34743664
Acanthosis 19.16 10.58 11 202629 120 34754171
Superinfection 19.14 10.58 44 202596 2475 34751816
Gastric perforation 19.13 10.58 44 202596 2476 34751815
Intestinal ulcer 19 10.58 25 202615 893 34753398
Glomerulonephritis proliferative 18.95 10.58 13 202627 198 34754093
Cerebral toxoplasmosis 18.91 10.58 35 202605 1686 34752605
Blastomycosis 18.91 10.58 18 202622 446 34753845
Lymph node tuberculosis 18.87 10.58 18 202622 447 34753844
Pulmonary mucormycosis 18.86 10.58 23 202617 760 34753531
Skin laceration 18.84 10.58 27 202613 12482 34741809
Tinnitus 18.83 10.58 57 202583 20061 34734230
Herpes zoster oticus 18.78 10.58 13 202627 201 34754090
Hyposplenism 18.75 10.58 6 202634 11 34754280
Uveitis 18.75 10.58 90 202550 7445 34746846
Escherichia urinary tract infection 18.71 10.58 54 202586 3492 34750799
Abscess fungal 18.71 10.58 14 202626 246 34754045
Phaeohyphomycotic brain abscess 18.68 10.58 8 202632 43 34754248
Middle insomnia 18.67 10.58 8 202632 6794 34747497
Blood cholesterol increased 18.66 10.58 59 202581 20484 34733807
Gallbladder necrosis 18.60 10.58 10 202630 95 34754196
Porokeratosis 18.60 10.58 10 202630 95 34754196
Scleroderma 18.58 10.58 33 202607 1539 34752752
Gastroenteritis bacterial 18.53 10.58 8 202632 44 34754247
Erythema multiforme 18.50 10.58 99 202541 8550 34745741
Spleen atrophy 18.45 10.58 5 202635 3 34754288
Cyclosporidium infection 18.42 10.58 6 202634 12 34754279
Mobility decreased 18.35 10.58 101 202539 30027 34724264
Leukoencephalopathy 18.34 10.58 60 202580 4155 34750136
Herpes simplex hepatitis 18.34 10.58 10 202630 98 34754193
Pulmonary air leakage 18.29 10.58 12 202628 169 34754122
Infective tenosynovitis 18.26 10.58 9 202631 70 34754221
Neutrophil count decreased 18.23 10.58 406 202234 50698 34703593
B-cell lymphoma refractory 18.17 10.58 12 202628 171 34754120
Product substitution issue 18.15 10.58 19 202621 10076 34744215
Serous retinal detachment 18.14 10.58 20 202620 592 34753699
Tularaemia 18.08 10.58 10 202630 101 34754190
Central nervous system infection 18.07 10.58 21 202619 659 34753632
Substance abuse 17.97 10.58 11 202629 7630 34746661
Pneumonia legionella 17.96 10.58 36 202604 1841 34752450
Post herpetic neuralgia 17.94 10.58 26 202614 1019 34753272
Limb injury 17.84 10.58 25 202615 11664 34742627
Microsporum infection 17.80 10.58 7 202633 29 34754262
Sebaceous gland disorder 17.80 10.58 7 202633 29 34754262
Central nervous system immune reconstitution inflammatory response 17.80 10.58 6 202634 14 34754277
Product complaint 17.71 10.58 6 202634 5884 34748407
Superinfection bacterial 17.68 10.58 24 202616 884 34753407
Mediastinitis 17.68 10.58 21 202619 675 34753616
Acute hepatitis B 17.65 10.58 12 202628 180 34754111
Seroma 17.64 10.58 20 202620 611 34753680
Facial paresis 17.63 10.58 48 202592 3001 34751290
Device leakage 17.63 10.58 8 202632 6567 34747724
Skin erosion 17.62 10.58 38 202602 2047 34752244
Growth disorder 17.61 10.58 7 202633 30 34754261
Cellulitis gangrenous 17.59 10.58 12 202628 181 34754110
Alcohol abuse 17.58 10.58 3 202637 4687 34749604
Intestinal villi atrophy 17.52 10.58 11 202629 143 34754148
Paresis 17.52 10.58 39 202601 2147 34752144
Biopsy kidney abnormal 17.51 10.58 10 202630 108 34754183
Meningitis bacterial 17.50 10.58 29 202611 1278 34753013
Hemianopia heteronymous 17.43 10.58 7 202633 31 34754260
Cow pox 17.43 10.58 7 202633 31 34754260
Bone marrow necrosis 17.42 10.58 12 202628 184 34754107
Fungal abscess central nervous system 17.35 10.58 10 202630 110 34754181
Sensation of foreign body 17.30 10.58 45 202595 2738 34751553
Proctocolectomy 17.27 10.58 10 202630 111 34754180
Hepatic infection fungal 17.26 10.58 12 202628 187 34754104
Neurofibrosarcoma 17.26 10.58 7 202633 32 34754259
Plantar fasciitis 17.24 10.58 38 202602 2078 34752213
Argentine haemorrhagic fever 17.24 10.58 6 202634 16 34754275
Microvillous inclusion disease 17.20 10.58 12 202628 188 34754103
Chronic graft versus host disease in liver 17.19 10.58 17 202623 442 34753849
Retinitis 17.16 10.58 16 202624 386 34753905
Gastrointestinal mucosa hyperaemia 17.15 10.58 14 202626 281 34754010
Diffuse alveolar damage 17.12 10.58 40 202600 2274 34752017
Skin discolouration 17.10 10.58 50 202590 17795 34736496
Cytomegalovirus hepatitis 17.07 10.58 17 202623 446 34753845
Tubulointerstitial nephritis and uveitis syndrome 17.06 10.58 9 202631 82 34754209
Hypochromic anaemia 17.05 10.58 24 202616 915 34753376
Bulbar palsy 17.02 10.58 13 202627 236 34754055
Papilloedema 17.00 10.58 44 202596 2669 34751622
Retroperitoneal neoplasm 16.97 10.58 6 202634 17 34754274
Sinus disorder 16.95 10.58 10 202630 7075 34747216
International normalised ratio decreased 16.94 10.58 3 202637 4564 34749727
Mediastinal abscess 16.94 10.58 8 202632 56 34754235
Autoimmune haemolytic anaemia 16.94 10.58 61 202579 4435 34749856
BRCA1 gene mutation 16.92 10.58 7 202633 34 34754257
Osteoarthritis 16.90 10.58 62 202578 20580 34733711
Cytopenia 16.88 10.58 129 202511 12594 34741697
Diffuse large B-cell lymphoma stage I 16.87 10.58 5 202635 6 34754285
Arteriosclerosis coronary artery 16.86 10.58 29 202611 12456 34741835
Anogenital warts 16.82 10.58 19 202621 578 34753713
Colitis 16.82 10.58 310 202330 37440 34716851
Ventricular tachycardia 16.80 10.58 88 202552 26491 34727800
Pleural adhesion 16.78 10.58 12 202628 196 34754095
Polyarteritis nodosa 16.78 10.58 14 202626 290 34754001
Protothecosis 16.75 10.58 7 202633 35 34754256
Hip fracture 16.75 10.58 27 202613 11898 34742393
Abnormal behaviour 16.73 10.58 81 202559 24888 34729403
Pneumococcal infection 16.73 10.58 17 202623 457 34753834
Neutropenic colitis 16.71 10.58 48 202592 3096 34751195
Sudden hearing loss 16.68 10.58 24 202616 934 34753357
Erysipelas 16.67 10.58 64 202576 4799 34749492
Cytomegalovirus myelomeningoradiculitis 16.63 10.58 4 202636 0 34754291
Alpha tumour necrosis factor increased 16.63 10.58 4 202636 0 34754291
Euphoric mood 16.53 10.58 6 202634 5635 34748656
Melanaemia 16.48 10.58 8 202632 60 34754231
Pulmonary artery thrombosis 16.47 10.58 21 202619 727 34753564
Scrotal ulcer 16.46 10.58 17 202623 466 34753825
Toxic epidermal necrolysis 16.46 10.58 195 202445 21451 34732840
Lung adenocarcinoma 16.44 10.58 62 202578 4609 34749682
Nephritis bacterial 16.44 10.58 5 202635 7 34754284
Blood lactate dehydrogenase 16.44 10.58 5 202635 7 34754284
Heart block congenital 16.44 10.58 7 202633 37 34754254
Chronic graft versus host disease in intestine 16.39 10.58 13 202627 250 34754041
Drug level increased 16.34 10.58 198 202442 21898 34732393
Ileal stenosis 16.34 10.58 29 202611 1352 34752939
Metastatic carcinoma of the bladder 16.32 10.58 12 202628 205 34754086
Paranoia 16.32 10.58 28 202612 12040 34742251
Gynaecomastia 16.32 10.58 21 202619 10159 34744132
Respiratory rate increased 16.29 10.58 20 202620 9874 34744417
Skin papilloma 16.27 10.58 37 202603 2066 34752225
Lupus nephritis 16.22 10.58 15 202625 358 34753933
Swelling 16.20 10.58 162 202478 42204 34712087
Necrosis 16.20 10.58 71 202569 5652 34748639
Squamous cell carcinoma of the oral cavity 16.18 10.58 12 202628 208 34754083
No adverse event 16.17 10.58 73 202567 22854 34731437
VIth nerve paralysis 16.17 10.58 22 202618 812 34753479
Myelopathy 16.16 10.58 41 202599 2456 34751835
Chronic graft versus host disease oral 16.06 10.58 10 202630 128 34754163
Cell marker increased 16.05 10.58 16 202624 420 34753871
Anorectal infection bacterial 16.05 10.58 5 202635 8 34754283
Gas gangrene 16.04 10.58 8 202632 64 34754227
Continuous haemodiafiltration 16.04 10.58 24 202616 968 34753323
Attention-seeking behaviour 16.00 10.58 7 202633 40 34754251
Leukaemic infiltration 15.99 10.58 10 202630 129 34754162
Eye pruritus 15.99 10.58 12 202628 7477 34746814
Chronic myeloid leukaemia 15.97 10.58 38 202602 2186 34752105
Klebsiella sepsis 15.94 10.58 36 202604 2001 34752290
Schizophrenia 15.93 10.58 16 202624 8650 34745641
Myoglobin blood increased 15.92 10.58 46 202594 2977 34751314
Immunodeficiency common variable 15.90 10.58 11 202629 170 34754121
Rectosigmoid cancer 15.90 10.58 11 202629 170 34754121
Tooth disorder 15.89 10.58 24 202616 10858 34743433
Urinary tract infection bacterial 15.89 10.58 35 202605 1913 34752378
Red blood cell count decreased 15.87 10.58 101 202539 28989 34725302
Flatulence 15.87 10.58 66 202574 21132 34733159
Monocyte percentage decreased 15.85 10.58 7 202633 41 34754250
Oral herpes 15.84 10.58 69 202571 5478 34748813
Myoclonus 15.82 10.58 39 202601 14686 34739605
Aplasia pure red cell 15.81 10.58 74 202566 6058 34748233
Infusion site extravasation 15.80 10.58 3 202637 4341 34749950
C3 glomerulopathy 15.73 10.58 8 202632 67 34754224
Bronchial carcinoma 15.70 10.58 24 202616 987 34753304
Blood phosphorus increased 15.69 10.58 13 202627 7708 34746583
Nocardia sepsis 15.69 10.58 5 202635 9 34754282
Smooth muscle cell neoplasm 15.68 10.58 11 202629 174 34754117
Mycobacterium kansasii infection 15.67 10.58 14 202626 319 34753972
Hydrocephalus 15.65 10.58 66 202574 5166 34749125
Respiratory tract congestion 15.65 10.58 8 202632 6131 34748160
Oesophageal fibrosis 15.63 10.58 11 202629 175 34754116
Eosinophil count increased 15.62 10.58 94 202546 8478 34745813
Intussusception 15.60 10.58 19 202621 627 34753664
Blood triglycerides increased 15.60 10.58 37 202603 14122 34740169
Dental fistula 15.54 10.58 9 202631 100 34754191
Transient ischaemic attack 15.52 10.58 95 202545 27518 34726773
Exophthalmos 15.49 10.58 18 202622 565 34753726
Pancreatic enzymes increased 15.46 10.58 19 202621 633 34753658
VIth nerve paresis 15.45 10.58 7 202633 44 34754247
Neutrophil morphology abnormal 15.44 10.58 8 202632 70 34754221
Wound infection pseudomonas 15.35 10.58 13 202627 275 34754016
Acute interstitial pneumonitis 15.34 10.58 16 202624 444 34753847
Pyuria 15.29 10.58 21 202619 782 34753509
Psychomotor hyperactivity 15.27 10.58 20 202620 9602 34744689
Myalgia 15.24 10.58 371 202269 83739 34670552
Graft versus host disease in liver 15.24 10.58 27 202613 1257 34753034
Abscess 15.23 10.58 119 202521 11698 34742593
Candida pneumonia 15.19 10.58 16 202624 449 34753842
Aortic aneurysm rupture 15.19 10.58 24 202616 1016 34753275
Priapism 15.17 10.58 5 202635 4989 34749302
Pseudarthrosis 15.15 10.58 8 202632 73 34754218
Cerebellar infarction 15.11 10.58 34 202606 1885 34752406
Purpura 15.08 10.58 107 202533 10204 34744087
Acute biphenotypic leukaemia 15.06 10.58 8 202632 74 34754217
Rheumatoid factor 15.06 10.58 8 202632 74 34754217
Prescribed underdose 15.05 10.58 96 202544 8837 34745454
Febrile infection 15.04 10.58 37 202603 2174 34752117
IVth nerve paralysis 14.95 10.58 9 202631 108 34754183
Epidural lipomatosis 14.95 10.58 24 202616 1030 34753261
Nerve conduction studies abnormal 14.82 10.58 7 202633 49 34754242
Prostatic abscess 14.80 10.58 16 202624 463 34753828
Blood urine present 14.78 10.58 25 202615 10809 34743482
Rectal perforation 14.77 10.58 16 202624 464 34753827
Neuralgia 14.73 10.58 42 202598 15071 34739220
Fundoscopy abnormal 14.73 10.58 5 202635 12 34754279
Coronary artery bypass 14.73 10.58 5 202635 4897 34749394
Multiple sclerosis relapse 14.73 10.58 34 202606 13099 34741192
Urethral obstruction 14.72 10.58 11 202629 193 34754098
Acute monocytic leukaemia 14.70 10.58 14 202626 347 34753944
Osteomyelitis fungal 14.69 10.58 12 202628 241 34754050
Pneumonia acinetobacter 14.67 10.58 9 202631 112 34754179
Sneezing 14.66 10.58 6 202634 5236 34749055
Gastrointestinal wall thickening 14.65 10.58 29 202611 1469 34752822
Chronic hepatitis 14.63 10.58 19 202621 670 34753621
Limb discomfort 14.61 10.58 26 202614 11021 34743270
Pneumonia pseudomonal 14.60 10.58 53 202587 3869 34750422
Haemorrhoids 14.58 10.58 40 202600 14535 34739756
Metastasis 14.58 10.58 55 202585 4089 34750202
Giant cell arteritis 14.58 10.58 21 202619 818 34753473
Hypomagnesaemia 14.57 10.58 71 202569 21780 34732511
Hypersensitivity pneumonitis 14.56 10.58 30 202610 1565 34752726
Disseminated strongyloidiasis 14.53 10.58 11 202629 197 34754094
Herpes oesophagitis 14.48 10.58 10 202630 154 34754137
Malignant neoplasm of conjunctiva 14.40 10.58 4 202636 3 34754288
Pseudallescheria infection 14.40 10.58 4 202636 3 34754288
Malabsorption 14.38 10.58 38 202602 2334 34751957
Infected skin ulcer 14.33 10.58 30 202610 1583 34752708
Coronary artery occlusion 14.31 10.58 26 202614 10936 34743355
Blood glucose fluctuation 14.28 10.58 3 202637 4041 34750250
Post procedural bile leak 14.27 10.58 13 202627 304 34753987
Back injury 14.26 10.58 3 202637 4038 34750253
Hepatitis 14.26 10.58 206 202434 23698 34730593
Retinal scar 14.24 10.58 13 202627 305 34753986
Acanthoma 14.20 10.58 6 202634 31 34754260
Anaplastic large-cell lymphoma 14.20 10.58 8 202632 84 34754207
Bronchopleural fistula 14.16 10.58 16 202624 487 34753804
Phlebitis infective 14.08 10.58 9 202631 121 34754170
Erythema infectiosum 14.05 10.58 10 202630 162 34754129
Removal of renal transplant 14.05 10.58 6 202634 32 34754259
Angina unstable 14.03 10.58 29 202611 11624 34742667
Influenza 13.99 10.58 203 202437 49463 34704828
Acute myocardial infarction 13.96 10.58 223 202417 53496 34700795
Lip squamous cell carcinoma 13.95 10.58 9 202631 123 34754168
Concomitant disease progression 13.93 10.58 39 202601 2479 34751812
Osteomyelitis bacterial 13.93 10.58 13 202627 314 34753977
Eructation 13.92 10.58 5 202635 4726 34749565
Mental impairment 13.91 10.58 24 202616 10298 34743993
Microangiopathy 13.91 10.58 22 202618 932 34753359
Myocardial calcification 13.90 10.58 6 202634 33 34754258
Viral cardiomyopathy 13.90 10.58 6 202634 33 34754258
Citrobacter infection 13.90 10.58 16 202624 497 34753794
Metastatic bronchial carcinoma 13.89 10.58 13 202627 315 34753976
Blood alkaline phosphatase increased 13.88 10.58 256 202384 30919 34723372
Neonatal lupus erythematosus 13.88 10.58 4 202636 4 34754287
Visual acuity reduced 13.87 10.58 149 202491 16000 34738291
Decreased appetite 13.87 10.58 806 201834 165586 34588705
Anal incontinence 13.86 10.58 15 202625 7834 34746457
Norovirus infection 13.85 10.58 10 202630 166 34754125
DNA antibody positive 13.83 10.58 7 202633 58 34754233
Diffuse large B-cell lymphoma stage III 13.83 10.58 7 202633 58 34754233
Autoimmune hepatitis 13.83 10.58 56 202584 4304 34749987
Vasculitic rash 13.82 10.58 22 202618 937 34753354
Graft versus host disease in lung 13.82 10.58 17 202623 567 34753724
Non-cirrhotic portal hypertension 13.78 10.58 12 202628 264 34754027
Spindle cell sarcoma 13.76 10.58 9 202631 126 34754165
Blood pressure abnormal 13.75 10.58 16 202624 8090 34746201
Erythrophagocytosis 13.75 10.58 6 202634 34 34754257
Lymphoma transformation 13.74 10.58 12 202628 265 34754026
Blood pressure ambulatory increased 13.73 10.58 7 202633 59 34754232
Papillitis 13.73 10.58 7 202633 59 34754232
Endocarditis enterococcal 13.73 10.58 8 202632 90 34754201
Cutaneous vasculitis 13.72 10.58 55 202585 4208 34750083
Disseminated cytomegaloviral infection 13.72 10.58 11 202629 215 34754076
Antithrombin III decreased 13.69 10.58 13 202627 321 34753970
Liver transplant failure 13.65 10.58 8 202632 91 34754200
Relapsing fever 13.64 10.58 10 202630 170 34754121
Herpes zoster cutaneous disseminated 13.64 10.58 10 202630 170 34754121
Connective tissue disorder 13.63 10.58 11 202629 217 34754074
Metastases to liver 13.63 10.58 130 202510 13533 34740758
Treatment noncompliance 13.63 10.58 101 202539 27999 34726292
Pneumaturia 13.61 10.58 6 202634 35 34754256
New onset diabetes after transplantation 13.61 10.58 6 202634 35 34754256
Aspergilloma 13.59 10.58 13 202627 324 34753967
Coronary artery aneurysm 13.58 10.58 8 202632 92 34754199
Prostatomegaly 13.56 10.58 7 202633 5334 34748957
Epididymitis 13.52 10.58 38 202602 2421 34751870
Blood HIV RNA increased 13.50 10.58 25 202615 1205 34753086
Loss of proprioception 13.49 10.58 14 202626 386 34753905
Splenic neoplasm malignancy unspecified 13.47 10.58 5 202635 17 34754274
Emphysema 13.45 10.58 98 202542 9427 34744864
Cardiac autonomic neuropathy 13.44 10.58 7 202633 62 34754229
Norovirus test positive 13.44 10.58 7 202633 62 34754229
Pulpitis dental 13.41 10.58 17 202623 585 34753706
Bursitis infective 13.39 10.58 17 202623 586 34753705
Gastroenteritis 13.38 10.58 135 202505 14265 34740026
Enterocolitis 13.36 10.58 86 202554 7940 34746351
Interleukin level increased 13.35 10.58 9 202631 133 34754158
Achromobacter infection 13.34 10.58 7 202633 63 34754228
Hepatic amoebiasis 13.34 10.58 7 202633 63 34754228
N-telopeptide urine increased 13.34 10.58 6 202634 37 34754254
Cryptitis 13.30 10.58 11 202629 225 34754066
Interleukin-2 receptor increased 13.29 10.58 9 202631 134 34754157
Cholangitis sclerosing 13.29 10.58 27 202613 1394 34752897
Poor quality sleep 13.27 10.58 17 202623 8239 34746052
Microangiopathic haemolytic anaemia 13.25 10.58 21 202619 891 34753400
Oedematous kidney 13.20 10.58 6 202634 38 34754253
Musculoskeletal disorder 13.17 10.58 10 202630 6194 34748097
Gout 13.17 10.58 62 202578 19191 34735100
Joint stiffness 13.14 10.58 27 202613 10846 34743445
Pulmonary oedema 13.13 10.58 195 202445 47334 34706957
Bacillus infection 13.09 10.58 12 202628 283 34754008
BRCA2 gene mutation 13.07 10.58 6 202634 39 34754252
Neuromyotonia 13.07 10.58 6 202634 39 34754252
Disorientation 13.07 10.58 126 202514 33062 34721229
Necrotising colitis 13.07 10.58 23 202617 1065 34753226
Electrocardiogram QRS complex prolonged 13.05 10.58 6 202634 4888 34749403
Thyroid stimulating hormone deficiency 13.05 10.58 5 202635 19 34754272
Actinomycosis 13.03 10.58 15 202625 466 34753825
Mycobacterium marinum infection 13.02 10.58 12 202628 285 34754006
Calciphylaxis 13.01 10.58 23 202617 1069 34753222
Acquired porokeratosis 13.00 10.58 4 202636 6 34754285
Adrenal atrophy 13.00 10.58 4 202636 6 34754285
Zika virus infection 13.00 10.58 4 202636 6 34754285
Abscess drainage 12.99 10.58 12 202628 286 34754005
Tuberculosis gastrointestinal 12.98 10.58 11 202629 233 34754058
Optic discs blurred 12.98 10.58 7 202633 67 34754224
Cutaneous T-cell lymphoma recurrent 12.95 10.58 6 202634 40 34754251
Sweat gland disorder 12.94 10.58 8 202632 101 34754190
Acid fast bacilli infection 12.94 10.58 8 202632 101 34754190
Secondary immunodeficiency 12.92 10.58 14 202626 406 34753885
Renal tubular acidosis 12.91 10.58 36 202604 2283 34752008
Keratitis fungal 12.90 10.58 9 202631 141 34754150
Dysarthria 12.89 10.58 134 202506 34648 34719643
Quadriplegia 12.89 10.58 31 202609 1796 34752495
Infected lymphocele 12.85 10.58 5 202635 20 34754271
Gastrointestinal erosion 12.84 10.58 14 202626 409 34753882
Abdominal tenderness 12.82 10.58 52 202588 3999 34750292
Nosocomial infection 12.81 10.58 24 202616 1167 34753124
Intentional product use issue 12.79 10.58 257 202383 59559 34694732
Coronary arterial stent insertion 12.78 10.58 4 202636 4125 34750166
Psychotic disorder 12.78 10.58 86 202554 24366 34729925
Pulse absent 12.77 10.58 9 202631 5794 34748497
Herpes simplex oesophagitis 12.75 10.58 10 202630 189 34754102
Polychondritis 12.75 10.58 11 202629 239 34754052
Peritoneal lesion 12.74 10.58 8 202632 104 34754187
Tardive dyskinesia 12.72 10.58 9 202631 5781 34748510
Human herpesvirus 6 encephalitis 12.72 10.58 13 202627 352 34753939
Lactobacillus infection 12.72 10.58 12 202628 294 34753997
Wound decomposition 12.71 10.58 7 202633 70 34754221
Joint injury 12.67 10.58 21 202619 9152 34745139
Plasma cell myeloma recurrent 12.66 10.58 5 202635 4460 34749831
Hepatitis B DNA increased 12.66 10.58 16 202624 549 34753742
Non-alcoholic steatohepatitis 12.65 10.58 21 202619 927 34753364
Bowen's disease 12.64 10.58 9 202631 146 34754145
Myocardiac abscess 12.62 10.58 4 202636 7 34754284
Malacoplakia vesicae 12.62 10.58 4 202636 7 34754284
Restless legs syndrome 12.62 10.58 18 202622 8336 34745955
Bradyphrenia 12.61 10.58 6 202634 4792 34749499
Henoch-Schonlein purpura 12.59 10.58 29 202611 1633 34752658
Rhinocerebral mucormycosis 12.59 10.58 16 202624 552 34753739
Eye infection staphylococcal 12.59 10.58 6 202634 43 34754248
Anorectal varices 12.59 10.58 6 202634 43 34754248
Granulomatous rosacea 12.59 10.58 9 202631 147 34754144
Cystoid macular oedema 12.58 10.58 18 202622 697 34753594
Corneal perforation 12.53 10.58 10 202630 194 34754097
Septic encephalopathy 12.48 10.58 8 202632 108 34754183
Type 3 diabetes mellitus 12.48 10.58 5 202635 22 34754269
Brucellosis 12.48 10.58 5 202635 22 34754269
Granulocytopenia neonatal 12.48 10.58 5 202635 22 34754269
Gastrointestinal necrosis 12.48 10.58 46 202594 3383 34750908
Transitional cell carcinoma metastatic 12.47 10.58 6 202634 44 34754247
Listeraemia 12.47 10.58 3 202637 0 34754291
Nodular vasculitis 12.47 10.58 3 202637 0 34754291
Immune complex level increased 12.47 10.58 3 202637 0 34754291
Skin hyperplasia 12.47 10.58 3 202637 0 34754291
Infective pericardial effusion 12.47 10.58 3 202637 0 34754291
Splint application 12.47 10.58 3 202637 0 34754291
Phagocytosis 12.47 10.58 3 202637 0 34754291
Congenital thrombocytopenia 12.47 10.58 3 202637 0 34754291
Arterial wall hypertrophy 12.47 10.58 3 202637 0 34754291
Encephalitis post varicella 12.47 10.58 3 202637 0 34754291
Metastatic neoplasm 12.43 10.58 42 202598 2958 34751333
Capnocytophaga infection 12.42 10.58 8 202632 109 34754182
Pulmonary necrosis 12.40 10.58 13 202627 363 34753928
Complications of transplanted heart 12.39 10.58 12 202628 304 34753987
Stent placement 12.38 10.58 7 202633 5071 34749220
Sinusitis fungal 12.37 10.58 16 202624 562 34753729
Gingival erythema 12.36 10.58 8 202632 110 34754181
Hypersensitivity vasculitis 12.35 10.58 45 202595 3290 34751001
Crystal urine 12.30 10.58 7 202633 75 34754216
Cerebral cyst 12.26 10.58 12 202628 308 34753983
Bladder transitional cell carcinoma stage III 12.25 10.58 6 202634 46 34754245
Disturbance in attention 12.23 10.58 94 202546 25851 34728440
Glomerulonephritis rapidly progressive 12.22 10.58 17 202623 641 34753650
Eosinophilic granulomatosis with polyangiitis 12.22 10.58 32 202608 1955 34752336
Respiratory tract infection 12.21 10.58 171 202469 19541 34734750
Feeling jittery 12.17 10.58 4 202636 3999 34750292
Oesophageal carcinoma 12.16 10.58 94 202546 9210 34745081
T-lymphocyte count decreased 12.15 10.58 10 202630 203 34754088
Drug withdrawal syndrome neonatal 12.15 10.58 3 202637 3616 34750675
Speech disorder 12.13 10.58 93 202547 25593 34728698
Chest wall abscess 12.13 10.58 9 202631 156 34754135
Helicobacter sepsis 12.13 10.58 5 202635 24 34754267
Hypocomplementaemia 12.13 10.58 5 202635 24 34754267
Biopsy site unspecified abnormal 12.13 10.58 5 202635 24 34754267
Encapsulating peritoneal sclerosis 12.13 10.58 16 202624 573 34753718
Prostate cancer metastatic 12.12 10.58 66 202574 5737 34748554
Drug therapeutic incompatibility 12.11 10.58 8 202632 114 34754177
Glaucoma 12.09 10.58 75 202565 6837 34747454
Hepatitis B e antigen positive 12.03 10.58 6 202634 48 34754243
Megakaryocytes increased 12.03 10.58 6 202634 48 34754243
Eye abscess 11.99 10.58 9 202631 159 34754132
Histiocytosis 11.96 10.58 4 202636 9 34754282
Neutrophil percentage abnormal 11.96 10.58 4 202636 9 34754282
Chlamydia test positive 11.96 10.58 4 202636 9 34754282
Lymphocyte percentage abnormal 11.96 10.58 4 202636 9 34754282
Ophthalmic herpes zoster 11.96 10.58 20 202620 888 34753403
Lung squamous cell carcinoma stage I 11.96 10.58 4 202636 9 34754282
Pityriasis lichenoides et varioliformis acuta 11.96 10.58 4 202636 9 34754282
Oropharyngeal candidiasis 11.96 10.58 19 202621 808 34753483
Blindness cortical 11.92 10.58 13 202627 380 34753911
Viral vasculitis 11.92 10.58 7 202633 80 34754211
Mucocutaneous leishmaniasis 11.92 10.58 7 202633 80 34754211
Blood pressure systolic abnormal 11.91 10.58 4 202636 3944 34750347
Intestinal intraepithelial lymphocytes increased 11.89 10.58 9 202631 161 34754130
Urinary tract obstruction 11.89 10.58 47 202593 3573 34750718
Hot flush 11.88 10.58 59 202581 18007 34736284
Gastric cancer 11.83 10.58 71 202569 6398 34747893
Alveolitis 11.82 10.58 29 202611 1701 34752590
Gastrointestinal haemorrhage 11.80 10.58 407 202233 88070 34666221
Enthesopathy 11.78 10.58 6 202634 4607 34749684
Abnormal dreams 11.77 10.58 16 202624 7562 34746729
Rectal ulcer 11.77 10.58 21 202619 983 34753308
Ileus paralytic 11.73 10.58 67 202573 5930 34748361
Wound dehiscence 11.70 10.58 44 202596 3267 34751024
Idiopathic pulmonary fibrosis 11.70 10.58 46 202594 3488 34750803
Mantle cell lymphoma recurrent 11.69 10.58 18 202622 745 34753546
Aortic dissection 11.68 10.58 39 202601 2729 34751562
Angioimmunoblastic T-cell lymphoma 11.68 10.58 12 202628 327 34753964
Musculoskeletal chest pain 11.68 10.58 25 202615 9893 34744398
Endotoxic shock 11.67 10.58 4 202636 10 34754281
Reticulocytosis 11.67 10.58 11 202629 269 34754022
Thinking abnormal 11.67 10.58 11 202629 6126 34748165
CSF glucose decreased 11.66 10.58 5 202635 27 34754264
Lacrimal gland enlargement 11.66 10.58 5 202635 27 34754264
Behaviour disorder 11.65 10.58 7 202633 4903 34749388
Sputum discoloured 11.63 10.58 17 202623 7795 34746496
Enteritis 11.62 10.58 84 202556 8058 34746233
Duodenal perforation 11.62 10.58 24 202616 1254 34753037
Ventricular arrhythmia 11.62 10.58 9 202631 5519 34748772
Intentional dose omission 11.56 10.58 3 202637 3497 34750794
Extradural abscess 11.55 10.58 19 202621 832 34753459
Mouth swelling 11.52 10.58 30 202610 1826 34752465
Asymptomatic viral hepatitis 11.51 10.58 5 202635 28 34754263
Renal and pancreas transplant rejection 11.51 10.58 5 202635 28 34754263
Haemorrhage 11.50 10.58 219 202421 51151 34703140
Acute myelomonocytic leukaemia 11.49 10.58 8 202632 125 34754166
Pulmonary sepsis 11.48 10.58 34 202606 2231 34752060
Cranial nerve palsies multiple 11.44 10.58 6 202634 54 34754237
Infected neoplasm 11.42 10.58 7 202633 87 34754204
Body tinea 11.42 10.58 7 202633 87 34754204
Body height decreased 11.41 10.58 4 202636 3839 34750452
Oesophageal tuberculosis 11.40 10.58 4 202636 11 34754280
Granulomatosis with polyangiitis 11.40 10.58 23 202617 1182 34753109
Congenital hepatobiliary anomaly 11.37 10.58 5 202635 29 34754262
Small for dates baby 11.33 10.58 49 202591 3878 34750413
Cystic lung disease 11.33 10.58 12 202628 339 34753952
Cystitis viral 11.31 10.58 15 202625 540 34753751
Muscle twitching 11.28 10.58 27 202613 10271 34744020
Cognitive disorder 11.27 10.58 109 202531 28584 34725707
Blood alkaline phosphatase abnormal 11.26 10.58 14 202626 472 34753819
Prolonged expiration 11.26 10.58 10 202630 226 34754065
Acanthamoeba infection 11.24 10.58 13 202627 406 34753885
Mouth ulceration 11.23 10.58 112 202528 11798 34742493
Peri-implantitis 11.22 10.58 8 202632 130 34754161
Epstein-Barr viraemia 11.19 10.58 24 202616 1288 34753003
Hepatitis C RNA increased 11.19 10.58 11 202629 284 34754007
Bronchiectasis 11.18 10.58 96 202544 9705 34744586
Necrotising fasciitis 11.17 10.58 47 202593 3675 34750616
Breast discomfort 11.15 10.58 4 202636 12 34754279
Gingival cancer 11.15 10.58 4 202636 12 34754279
Peripheral T-cell lymphoma unspecified refractory 11.15 10.58 4 202636 12 34754279
Tooth erosion 11.15 10.58 7 202633 91 34754200
Pancreatic duct stenosis 11.13 10.58 9 202631 178 34754113
Adrenocortical insufficiency acute 11.13 10.58 27 202613 1573 34752718
Urinary tract infection 11.12 10.58 595 202045 83486 34670805
Typhoid fever 11.09 10.58 5 202635 31 34754260
Viral uveitis 11.09 10.58 5 202635 31 34754260
Oesophagopleural fistula 11.07 10.58 6 202634 58 34754233
Gastrosplenic fistula 11.07 10.58 6 202634 58 34754233
Rectal cancer 11.06 10.58 33 202607 2174 34752117
Cavernous sinus thrombosis 11.05 10.58 9 202631 180 34754111
Body height below normal 11.04 10.58 10 202630 232 34754059
Rheumatoid factor increased 11.04 10.58 15 202625 553 34753738
Neuroendocrine carcinoma 11.04 10.58 13 202627 414 34753877
Hiatus hernia 11.03 10.58 17 202623 7628 34746663
Lupus pneumonitis 10.98 10.58 6 202634 59 34754232
Steroid dependence 10.98 10.58 26 202614 1491 34752800
Delusion 10.98 10.58 37 202603 12598 34741693
Drug level changed 10.97 10.58 12 202628 352 34753939
Purulence 10.96 10.58 19 202621 869 34753422
Xanthelasma 10.95 10.58 7 202633 94 34754197
Anaphylactoid reaction 10.94 10.58 34 202606 2291 34752000
Infective pulmonary exacerbation of cystic fibrosis 10.93 10.58 14 202626 6787 34747504
Antiphospholipid syndrome 10.93 10.58 14 202626 487 34753804
Neurosarcoidosis 10.93 10.58 9 202631 183 34754108
Respiratory tract infection fungal 10.93 10.58 17 202623 710 34753581
Cardiac myxoma 10.91 10.58 4 202636 13 34754278
Retinal disorder 10.90 10.58 20 202620 957 34753334
Pancreatitis necrotising 10.89 10.58 38 202602 2720 34751571
Rotator cuff syndrome 10.89 10.58 10 202630 5639 34748652
Hypophagia 10.87 10.58 88 202552 23934 34730357
Hand deformity 10.85 10.58 4 202636 3721 34750570
Haemosiderosis 10.85 10.58 11 202629 295 34753996
Peripheral vascular disorder 10.84 10.58 8 202632 5028 34749263
Hepatic artery thrombosis 10.83 10.58 10 202630 238 34754053
Snoring 10.80 10.58 3 202637 3343 34750948
Squamous cell carcinoma of lung 10.79 10.58 30 202610 1899 34752392
Duodenal ulcer perforation 10.78 10.58 27 202613 1605 34752686
Soft tissue infection 10.77 10.58 33 202607 2207 34752084
Atrial flutter 10.74 10.58 50 202590 15524 34738767
Chronic kidney disease 10.73 10.58 171 202469 41039 34713252
Pneumonia mycoplasmal 10.72 10.58 16 202624 644 34753647
Atypical mycobacterial pneumonia 10.72 10.58 8 202632 140 34754151
Neuroborreliosis 10.71 10.58 5 202635 34 34754257
Paternal exposure timing unspecified 10.71 10.58 5 202635 34 34754257
Disorder of orbit 10.71 10.58 7 202633 98 34754193
Abdominal wall haematoma 10.70 10.58 29 202611 1808 34752483
Hormone-refractory prostate cancer 10.70 10.58 17 202623 723 34753568
Ewing's sarcoma 10.69 10.58 4 202636 14 34754277
Hepatocellular injury 10.69 10.58 80 202560 22131 34732160
Angioimmunoblastic T-cell lymphoma stage IV 10.69 10.58 4 202636 14 34754277
Ureteritis 10.69 10.58 4 202636 14 34754277
Dystonia 10.68 10.58 30 202610 10815 34743476
Orthostatic intolerance 10.67 10.58 18 202622 805 34753486
Pharyngeal ulceration 10.65 10.58 12 202628 364 34753927
Metastases to abdominal wall 10.65 10.58 7 202633 99 34754192
Dizziness postural 10.64 10.58 12 202628 6152 34748139
Mucosal ulceration 10.64 10.58 20 202620 975 34753316
Optic neuritis 10.62 10.58 45 202595 3529 34750762
Salmonella bacteraemia 10.62 10.58 8 202632 142 34754149
Immune thrombocytopenia 10.62 10.58 90 202550 9062 34745229
Fluid retention 10.62 10.58 102 202538 26785 34727506
Engraftment syndrome 10.61 10.58 20 202620 977 34753314

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cytomegalovirus infection 1895.12 9.65 1605 384576 41039 79317168
Pneumocystis jirovecii pneumonia 1831.94 9.65 1406 384775 31102 79327105
Completed suicide 923.48 9.65 70 386111 245697 79112510
Fatigue 802.97 9.65 2107 384074 927620 78430587
Product use in unapproved indication 738.38 9.65 2775 383406 247584 79110623
Pain 692.73 9.65 1487 384694 702315 78655892
Product dose omission issue 682.62 9.65 178 386003 247359 79110848
Post transplant lymphoproliferative disorder 661.34 9.65 503 385678 10961 79347246
Interstitial lung disease 623.22 9.65 1557 384624 111043 79247164
Bronchopulmonary aspergillosis 619.83 9.65 647 385534 21647 79336560
Transplant rejection 611.39 9.65 603 385578 18834 79339373
Nocardiosis 606.41 9.65 365 385816 5314 79352893
Epstein-Barr virus infection 596.25 9.65 521 385660 13895 79344312
Hepatitis B 588.11 9.65 413 385768 7919 79350288
Lymphoproliferative disorder 581.83 9.65 354 385827 5261 79352946
Drug abuse 534.79 9.65 76 386105 162615 79195592
Sepsis 534.74 9.65 2650 383531 266778 79091429
Diffuse large B-cell lymphoma 512.39 9.65 444 385737 11705 79346502
Haemophagocytic lymphohistiocytosis 511.47 9.65 579 385602 21258 79336949
Osteonecrosis 482.57 9.65 671 385510 30424 79327783
Polyomavirus-associated nephropathy 468.69 9.65 309 385872 5318 79352889
Renal impairment 444.94 9.65 1725 384456 156058 79202149
Posterior reversible encephalopathy syndrome 440.96 9.65 589 385592 25692 79332515
Strongyloidiasis 430.40 9.65 256 385925 3642 79354565
Hepatic function abnormal 422.44 9.65 1028 385153 72079 79286128
Death 420.41 9.65 1376 384805 565138 78793069
Hepatitis B reactivation 413.14 9.65 295 385886 5813 79352394
Off label use 412.45 9.65 6416 379765 900799 78457408
Aspergillus infection 410.08 9.65 485 385696 18676 79339531
Nausea 406.29 9.65 2844 383337 954352 78403855
Kidney transplant rejection 401.19 9.65 359 385822 9887 79348320
Pyrexia 389.95 9.65 5004 381177 673705 78684502
Disseminated intravascular coagulation 371.59 9.65 642 385539 35200 79323007
Injection site pain 364.19 9.65 90 386091 129748 79228459
Epstein-Barr virus associated lymphoproliferative disorder 361.66 9.65 221 385960 3311 79354896
Varicella zoster virus infection 358.11 9.65 239 385942 4202 79354005
Respiratory failure 355.43 9.65 1775 384406 179136 79179071
Multiple organ dysfunction syndrome 349.86 9.65 1328 384853 118918 79239289
Hepatitis E 347.79 9.65 203 385978 2783 79355424
Thrombotic microangiopathy 346.02 9.65 457 385724 19712 79338495
Complications of transplanted kidney 340.30 9.65 267 385914 6099 79352108
Cytomegalovirus viraemia 340.21 9.65 363 385818 12458 79345749
Cytomegalovirus colitis 339.46 9.65 236 385945 4449 79353758
Overdose 334.90 9.65 242 385939 183964 79174243
Progressive multifocal leukoencephalopathy 333.88 9.65 454 385727 20146 79338061
Steroid diabetes 327.68 9.65 207 385974 3299 79354908
Drug hypersensitivity 326.30 9.65 593 385588 298323 79059884
BK virus infection 314.47 9.65 293 385888 8511 79349696
Fall 312.81 9.65 1258 384923 486371 78871836
Septic shock 308.91 9.65 1296 384885 121505 79236702
Cytomegalovirus infection reactivation 305.42 9.65 287 385894 8429 79349778
Anxiety 301.79 9.65 460 385721 248052 79110155
Toxicity to various agents 299.29 9.65 1043 385138 420497 78937710
Asthenia 297.67 9.65 1370 384811 510319 78847888
Hypogammaglobulinaemia 297.52 9.65 340 385841 12611 79345596
Hypotension 295.11 9.65 1116 385065 439201 78919006
Osteonecrosis of jaw 292.67 9.65 647 385534 42579 79315628
Dizziness 288.46 9.65 1440 384741 525001 78833206
Pulmonary nocardiosis 287.13 9.65 136 386045 1175 79357032
Pancytopenia 283.38 9.65 1565 384616 164180 79194027
Pulmonary tuberculosis 283.34 9.65 263 385918 7602 79350605
Headache 279.78 9.65 1936 384245 651836 78706371
Chorioretinopathy 279.38 9.65 159 386022 2072 79356135
Polyomavirus viraemia 278.65 9.65 145 386036 1562 79356645
Abdominal discomfort 275.72 9.65 495 385686 250232 79107975
Pain in extremity 266.12 9.65 891 385290 363647 78994560
Leukopenia 265.76 9.65 1194 384987 115319 79242888
Disease recurrence 265.23 9.65 630 385551 43479 79314728
Immunosuppressant drug level increased 259.93 9.65 267 385914 8760 79349447
Joint swelling 256.26 9.65 643 385538 288003 79070204
Feeling abnormal 255.95 9.65 236 385945 158963 79199244
Intentional overdose 253.11 9.65 98 386083 105862 79252345
Blood pressure increased 250.12 9.65 398 385783 210962 79147245
Pneumatosis intestinalis 248.20 9.65 223 385958 6174 79352033
Sinusitis 242.03 9.65 357 385824 195144 79163063
Mucormycosis 241.16 9.65 249 385932 8220 79349987
Alveolar proteinosis 240.14 9.65 103 386078 686 79357521
Brain abscess 238.24 9.65 195 385986 4741 79353466
Disseminated tuberculosis 237.87 9.65 182 385999 4001 79354206
Arthralgia 236.77 9.65 1709 384472 570094 78788113
Cryptococcosis 234.63 9.65 168 386013 3325 79354882
General physical health deterioration 233.28 9.65 2194 383987 273044 79085163
Cushingoid 230.03 9.65 257 385924 9295 79348912
Pneumonia bacterial 228.10 9.65 367 385814 18964 79339243
Peripheral swelling 225.29 9.65 619 385562 268998 79089209
Blood lactate dehydrogenase increased 218.99 9.65 544 385637 38626 79319581
JC virus infection 218.81 9.65 168 386013 3713 79354494
Arthropathy 210.00 9.65 333 385848 176778 79181429
Nasopharyngitis 209.78 9.65 586 385595 253295 79104912
Cytomegalovirus test positive 208.72 9.65 196 385985 5751 79352456
Pneumomediastinum 207.32 9.65 159 386022 3508 79354699
Acute respiratory distress syndrome 205.53 9.65 572 385609 43495 79314712
Weight increased 200.94 9.65 680 385501 276706 79081501
Escherichia infection 200.33 9.65 333 385848 17684 79340523
Drug intolerance 199.94 9.65 635 385546 263484 79094723
Pneumonia cytomegaloviral 198.30 9.65 176 386005 4793 79353414
Blood pressure fluctuation 191.27 9.65 45 386136 67100 79291107
Muscle spasms 191.07 9.65 346 385835 174384 79183823
Depression 187.65 9.65 489 385692 216301 79141906
Transplant failure 184.44 9.65 164 386017 4477 79353730
Transplant dysfunction 183.77 9.65 200 385981 7021 79351186
COVID-19 181.61 9.65 1347 384834 156327 79201880
Pseudomonas infection 180.56 9.65 346 385835 20557 79337650
Liver disorder 179.47 9.65 761 385420 71656 79286551
Atypical femur fracture 176.35 9.65 168 386013 5021 79353186
Adenovirus infection 176.10 9.65 211 385970 8236 79349971
Cardiac failure congestive 175.26 9.65 261 385920 142141 79216066
Phaeohyphomycosis 173.69 9.65 94 386087 1103 79357104
Wrong technique in product usage process 173.67 9.65 70 386111 73805 79284402
Herpes zoster 172.63 9.65 899 385282 92184 79266023
Synovitis 172.51 9.65 290 385891 150444 79207763
Viraemia 172.37 9.65 129 386052 2740 79355467
Infection reactivation 172.09 9.65 125 386056 2532 79355675
Cytomegalovirus chorioretinitis 172.03 9.65 170 386011 5320 79352887
Swelling 168.94 9.65 514 385667 216197 79142010
Febrile neutropenia 168.81 9.65 1786 384395 229213 79128994
Bradycardia 167.27 9.65 248 385933 135309 79222898
Insomnia 164.24 9.65 621 385560 244549 79113658
Herpes simplex 164.22 9.65 246 385935 11941 79346266
Cerebrovascular accident 160.57 9.65 318 385863 154974 79203233
Rebound effect 158.08 9.65 185 385996 7041 79351166
Hospitalisation 157.06 9.65 135 386046 94101 79264106
Epstein Barr virus positive mucocutaneous ulcer 156.90 9.65 78 386103 757 79357450
Inappropriate schedule of product administration 156.72 9.65 253 385928 133375 79224832
Stress 156.18 9.65 96 386085 79516 79278691
Cytomegalovirus enterocolitis 155.39 9.65 98 386083 1557 79356650
Weight decreased 150.94 9.65 1053 385128 354145 79004062
Atypical mycobacterial infection 150.74 9.65 98 386083 1645 79356562
Heart rate decreased 150.63 9.65 76 386105 70240 79287967
Injection site erythema 149.68 9.65 97 386084 78100 79280107
Meningitis cryptococcal 149.59 9.65 129 386052 3377 79354830
Sedation 149.36 9.65 34 386147 51861 79306346
Confusional state 149.14 9.65 915 385266 317082 79041125
Acquired gene mutation 149.07 9.65 107 386074 2126 79356081
Hand deformity 148.90 9.65 170 386011 103749 79254458
Blood pressure systolic increased 148.68 9.65 69 386112 66917 79291290
Somnolence 148.24 9.65 624 385557 238357 79119850
Diabetes mellitus 148.05 9.65 761 385420 77629 79280578
Nasal congestion 147.84 9.65 94 386087 76458 79281749
Therapy partial responder 146.63 9.65 285 385896 17112 79341095
Angiocentric lymphoma 144.91 9.65 76 386105 833 79357374
Pneumonia 143.98 9.65 4199 381982 656047 78702160
Lymphopenia 143.83 9.65 398 385783 30159 79328048
Pruritus 143.73 9.65 1221 384960 393427 78964780
Epstein-Barr virus infection reactivation 143.42 9.65 98 386083 1794 79356413
Heart rate increased 142.11 9.65 228 385953 120496 79237711
Disseminated cryptococcosis 141.41 9.65 96 386085 1738 79356469
Therapeutic product effect decreased 140.70 9.65 371 385810 163492 79194715
Bone marrow failure 140.01 9.65 554 385627 50553 79307654
Electrocardiogram QT prolonged 139.39 9.65 139 386042 90247 79267960
Substance-induced psychotic disorder 139.16 9.65 122 386059 3267 79354940
Back pain 139.13 9.65 882 385299 303298 79054909
Premature delivery 138.70 9.65 333 385848 23134 79335073
Pneumothorax 138.39 9.65 374 385807 27949 79330258
Tuberculosis 138.01 9.65 257 385924 14941 79343266
Upper respiratory tract inflammation 137.81 9.65 131 386050 3904 79354303
Injection site reaction 137.03 9.65 47 386134 54738 79303469
Drug resistance 136.82 9.65 483 385698 41730 79316477
Organising pneumonia 136.39 9.65 213 385968 10726 79347481
Graft versus host disease 136.33 9.65 254 385927 14772 79343435
Enterococcal infection 136.23 9.65 260 385921 15400 79342807
Neutropenic sepsis 135.90 9.65 361 385820 26703 79331504
Chronic graft versus host disease 135.85 9.65 166 386015 6615 79351592
Musculoskeletal stiffness 135.72 9.65 416 385765 174592 79183615
Parvovirus B19 infection 134.87 9.65 86 386095 1394 79356813
Pneumocystis jirovecii infection 134.81 9.65 112 386069 2782 79355425
Mycobacterial infection 134.73 9.65 124 386057 3544 79354663
Pneumonia cryptococcal 134.45 9.65 87 386094 1448 79356759
Scleroderma renal crisis 133.63 9.65 63 386118 538 79357669
Mental status changes 132.38 9.65 80 386101 66879 79291328
Balance disorder 131.82 9.65 171 386010 98686 79259521
Mycobacterium abscessus infection 131.65 9.65 79 386102 1143 79357064
Suicide attempt 129.66 9.65 126 386055 82806 79275401
Nephropathy toxic 128.57 9.65 297 385884 20122 79338085
Immunosuppression 128.34 9.65 226 385955 12577 79345630
Peritonitis 127.86 9.65 361 385820 27675 79330532
Diffuse large B-cell lymphoma recurrent 125.79 9.65 127 386054 4080 79354127
Glossodynia 125.59 9.65 191 385990 103146 79255061
Hepatic failure 122.45 9.65 604 385577 60608 79297599
Adult T-cell lymphoma/leukaemia 122.32 9.65 50 386131 290 79357917
Nephrotic syndrome 122.19 9.65 205 385976 10969 79347238
Gait disturbance 121.87 9.65 553 385628 206953 79151254
Hypersensitivity 121.65 9.65 757 385424 261482 79096725
Liver transplant rejection 121.64 9.65 111 386070 3137 79355070
Drug ineffective for unapproved indication 120.46 9.65 530 385651 50708 79307499
Lung abscess 119.07 9.65 122 386059 3990 79354217
Alopecia 118.97 9.65 646 385535 230709 79127498
Constipation 118.77 9.65 842 385339 282208 79075999
Intentional product misuse 118.46 9.65 173 386008 94992 79263215
Central nervous system lymphoma 118.04 9.65 94 386087 2195 79356012
Cytomegalovirus enteritis 115.55 9.65 63 386118 751 79357456
Unevaluable event 114.75 9.65 63 386118 55522 79302685
Hyperglycaemia 113.38 9.65 654 385527 69681 79288526
Injection site bruising 111.90 9.65 30 386151 40972 79317235
Oesophageal candidiasis 111.48 9.65 177 386004 9041 79349166
Lymphocytic infiltration 109.64 9.65 77 386104 1476 79356731
Immunosuppressant drug level decreased 109.16 9.65 85 386096 1919 79356288
Migraine 108.96 9.65 159 386022 87334 79270873
Muscle abscess 108.65 9.65 67 386114 1021 79357186
Pemphigus 108.10 9.65 198 385983 99384 79258823
Gamma-glutamyltransferase increased 106.86 9.65 536 385645 54144 79304063
Discomfort 106.61 9.65 286 385895 125331 79232876
C-reactive protein increased 106.38 9.65 1023 385158 128004 79230203
Myopathy 106.01 9.65 277 385904 20286 79337921
Psoriasis 105.61 9.65 169 386012 89418 79268789
Injection site swelling 105.45 9.65 48 386133 47084 79311123
Large intestine perforation 105.39 9.65 224 385957 14343 79343864
Serotonin syndrome 105.28 9.65 43 386138 44984 79313223
Agranulocytosis 103.00 9.65 462 385719 44568 79313639
Proteinuria 102.85 9.65 369 385812 32133 79326074
Visceral leishmaniasis 101.70 9.65 65 386116 1058 79357149
Contraindicated product administered 101.61 9.65 405 385776 157133 79201074
Encephalitis 101.10 9.65 222 385959 14538 79343669
Incorrect dose administered 100.68 9.65 134 386047 76496 79281711
Lymphoma 100.24 9.65 245 385936 17215 79340992
Neuroleptic malignant syndrome 100.21 9.65 9 386172 27550 79330657
Illness 100.02 9.65 50 386131 46461 79311746
Hyperhidrosis 99.91 9.65 386 385795 151106 79207101
Trichophytosis 99.58 9.65 45 386136 345 79357862
Staphylococcal infection 99.21 9.65 550 385631 57745 79300462
Arthritis bacterial 98.69 9.65 167 386014 8999 79349208
Myelodysplastic syndrome 98.44 9.65 347 385834 29954 79328253
Cerebral infarction 98.07 9.65 460 385721 45216 79312991
Pleurisy 97.45 9.65 179 386002 10296 79347911
Mycobacterium chelonae infection 96.04 9.65 86 386095 2370 79355837
Contusion 94.99 9.65 384 385797 148392 79209815
Klebsiella infection 94.99 9.65 225 385956 15495 79342712
Osteoporosis 94.41 9.65 514 385667 53598 79304609
Chronic allograft nephropathy 94.13 9.65 73 386108 1638 79356569
Adrenal insufficiency 94.08 9.65 328 385853 28159 79330048
Symptom masked 93.70 9.65 67 386114 1323 79356884
Injection site pruritus 93.14 9.65 44 386137 42239 79315968
Anti-cyclic citrullinated peptide antibody positive 92.31 9.65 163 386018 82980 79275227
Rhinorrhoea 92.05 9.65 141 386040 75933 79282274
Therapy interrupted 91.27 9.65 20 386161 31321 79326886
Subcutaneous emphysema 91.08 9.65 73 386108 1721 79356486
Gastrooesophageal reflux disease 91.01 9.65 234 385947 104012 79254195
Memory impairment 90.64 9.65 260 385921 111474 79246733
Infectious pleural effusion 90.61 9.65 101 386080 3643 79354564
Loss of personal independence in daily activities 90.52 9.65 229 385952 102351 79255856
Lupus nephritis 90.30 9.65 91 386090 2917 79355290
Platelet count decreased 89.62 9.65 1382 384799 193282 79164925
Tendon rupture 89.50 9.65 188 385993 11938 79346269
Full blood count abnormal 89.34 9.65 42 386139 40432 79317775
Cerebral toxoplasmosis 89.00 9.65 81 386100 2281 79355926
Necrotising retinitis 88.53 9.65 62 386119 1183 79357024
COVID-19 pneumonia 88.30 9.65 324 385857 28525 79329682
Obliterative bronchiolitis 87.97 9.65 90 386091 2938 79355269
Therapy cessation 87.61 9.65 36 386145 37526 79320681
Human herpesvirus 8 infection 87.32 9.65 61 386120 1159 79357048
Myocardial infarction 87.18 9.65 528 385653 183601 79174606
Renal transplant failure 87.16 9.65 73 386108 1834 79356373
Pleural effusion 87.07 9.65 1081 385100 144181 79214026
Neutropenia 87.07 9.65 1913 384268 285797 79072410
Systemic candida 87.00 9.65 133 386048 6573 79351634
Kaposi's sarcoma 86.81 9.65 51 386130 708 79357499
Suicidal ideation 86.27 9.65 148 386033 76192 79282015
Acute graft versus host disease 86.22 9.65 167 386014 10000 79348207
Device issue 85.96 9.65 14 386167 27094 79331113
Accidental exposure to product 85.32 9.65 23 386158 31299 79326908
Bacterial sepsis 85.15 9.65 147 386034 8051 79350156
Spinal compression fracture 84.93 9.65 226 385955 16732 79341475
Staphylococcal sepsis 84.92 9.65 207 385974 14519 79343688
Enterocolitis 84.77 9.65 205 385976 14307 79343900
Cardio-respiratory arrest 84.76 9.65 257 385924 108253 79249954
Acute graft versus host disease in skin 84.41 9.65 141 386040 7517 79350690
Candida infection 84.36 9.65 388 385793 37826 79320381
Intentional self-injury 84.27 9.65 26 386155 32393 79325814
Systemic infection 83.70 9.65 161 386020 9591 79348616
Product quality issue 83.36 9.65 30 386151 33910 79324297
Heart transplant rejection 82.15 9.65 64 386117 1446 79356761
Systemic mycosis 80.66 9.65 81 386100 2585 79355622
Blood beta-D-glucan increased 80.66 9.65 44 386137 525 79357682
Dehydration 80.62 9.65 790 385391 247397 79110810
Infusion related reaction 80.30 9.65 720 385461 229517 79128690
Poisoning 80.25 9.65 13 386168 25259 79332948
Toxic epidermal necrolysis 80.16 9.65 427 385754 44154 79314053
Paraesthesia 80.16 9.65 512 385669 175811 79182396
Mycetoma mycotic 79.80 9.65 29 386152 115 79358092
Lung infiltration 79.32 9.65 268 385913 22644 79335563
Diarrhoea 79.19 9.65 3473 382708 877016 78481191
Unresponsive to stimuli 79.10 9.65 92 386089 55696 79302511
Alanine aminotransferase increased 78.23 9.65 1163 385018 161407 79196800
Varicella zoster pneumonia 78.09 9.65 29 386152 124 79358083
Endocarditis 77.87 9.65 164 386017 10433 79347774
Renal phospholipidosis 77.67 9.65 27 386154 91 79358116
Neck pain 77.43 9.65 155 386026 75262 79282945
Mycobacterium marinum infection 77.02 9.65 40 386141 429 79357778
Dyspepsia 76.87 9.65 269 385912 108418 79249789
Listeriosis 76.75 9.65 73 386108 2177 79356030
Infection in an immunocompromised host 76.64 9.65 59 386122 1309 79356898
Dermoid cyst 76.50 9.65 35 386146 277 79357930
Pyelonephritis 76.43 9.65 245 385936 20143 79338064
Full blood count decreased 76.32 9.65 18 386163 26801 79331406
Steroid withdrawal syndrome 76.10 9.65 46 386135 675 79357532
Listeria sepsis 75.72 9.65 47 386134 725 79357482
Subcutaneous abscess 75.42 9.65 137 386044 7812 79350395
Fungal endocarditis 74.85 9.65 43 386138 571 79357636
Nervousness 74.80 9.65 34 386147 33381 79324826
Oxygen saturation decreased 74.48 9.65 346 385835 128701 79229506
Osteoporotic fracture 74.15 9.65 97 386084 4143 79354064
Tubulointerstitial nephritis 74.14 9.65 374 385807 37861 79320346
Joint stiffness 73.67 9.65 54 386127 40776 79317431
Vasculitis 73.55 9.65 278 385903 24824 79333383
Tumour lysis syndrome 73.38 9.65 269 385912 23670 79334537
Injection site haemorrhage 73.08 9.65 22 386159 27848 79330359
Tremor 72.73 9.65 503 385678 169580 79188627
Mycobacterium avium complex infection 72.45 9.65 100 386081 4500 79353707
Respiratory arrest 72.22 9.65 104 386077 57446 79300761
Opportunistic infection 72.11 9.65 80 386101 2870 79355337
Pneumoperitoneum 72.07 9.65 82 386099 3026 79355181
Cutaneous nocardiosis 72.00 9.65 30 386151 184 79358023
Small intestinal perforation 71.44 9.65 84 386097 3213 79354994
Retinal detachment 71.34 9.65 146 386035 9101 79349106
Adrenal suppression 71.18 9.65 57 386124 1342 79356865
Agitation 71.05 9.65 246 385935 99469 79258738
Hypoalbuminaemia 71.01 9.65 246 385935 21051 79337156
Bacterial infection 70.83 9.65 320 385861 30960 79327247
Blood glucose increased 70.74 9.65 301 385880 114674 79243533
Influenza like illness 70.56 9.65 151 386030 71556 79286651
Growth retardation 70.04 9.65 65 386116 1878 79356329
Burning sensation 69.67 9.65 110 386071 58522 79299685
Ear infection 69.66 9.65 40 386141 34392 79323815
Emotional distress 69.38 9.65 55 386126 39914 79318293
Squamous cell carcinoma of skin 69.25 9.65 186 385995 13847 79344360
Eosinophilic granulomatosis with polyangiitis 69.15 9.65 87 386094 3573 79354634
Irritable bowel syndrome 69.11 9.65 122 386059 62119 79296088
Endocarditis bacterial 68.79 9.65 58 386123 1471 79356736
Aplasia pure red cell 68.34 9.65 130 386051 7680 79350527
Bacteraemia 67.87 9.65 327 385854 32497 79325710
Loss of consciousness 67.77 9.65 505 385676 167438 79190769
Hypoaesthesia 67.38 9.65 550 385631 178802 79179405
Intestinal perforation 66.77 9.65 211 385970 17215 79340992
Cytomegalovirus oesophagitis 66.38 9.65 43 386138 717 79357490
Cystitis haemorrhagic 66.30 9.65 141 386040 9031 79349176
Red blood cell sedimentation rate abnormal 66.08 9.65 11 386170 20952 79337255
Myelosuppression 65.79 9.65 376 385805 39920 79318287
Blood pressure diastolic decreased 65.70 9.65 32 386149 30184 79328023
Drug ineffective 65.65 9.65 6079 380102 1074834 78283373
Splenic abscess 65.43 9.65 39 386142 557 79357650
Fluid retention 65.41 9.65 151 386030 69658 79288549
Lung consolidation 65.21 9.65 138 386043 8809 79349398
Peripheral T-cell lymphoma unspecified 65.14 9.65 41 386140 649 79357558
Exposure during pregnancy 65.13 9.65 763 385418 100369 79257838
Wound 64.99 9.65 315 385866 115864 79242343
Angiosarcoma 64.97 9.65 36 386145 444 79357763
Injection site mass 64.96 9.65 10 386171 20174 79338033
Epstein-Barr viraemia 64.90 9.65 66 386115 2139 79356068
Multiple sclerosis relapse 64.62 9.65 78 386103 46455 79311752
Sweat gland tumour 64.43 9.65 37 386144 491 79357716
Scedosporium infection 64.32 9.65 55 386126 1423 79356784
Cardiac disorder 64.26 9.65 139 386042 65618 79292589
Coma 64.09 9.65 260 385921 100389 79257818
Cytogenetic abnormality 64.08 9.65 49 386132 1076 79357131
B-cell lymphoma 63.97 9.65 111 386070 6104 79352103
Acinetobacter infection 63.94 9.65 73 386108 2704 79355503
Dry skin 63.77 9.65 147 386034 67848 79290359
Poisoning deliberate 63.72 9.65 8 386173 18820 79339387
Gastrointestinal perforation 63.68 9.65 110 386071 6027 79352180
Enterococcal sepsis 63.34 9.65 72 386109 2654 79355553
Oral candidiasis 63.32 9.65 298 385883 29330 79328877
Prostatic specific antigen increased 63.12 9.65 149 386032 10237 79347970
Throat irritation 63.08 9.65 63 386118 40883 79317324
Pneumonia fungal 62.97 9.65 156 386025 11054 79347153
Pneumonia adenoviral 62.80 9.65 36 386145 476 79357731
Delayed graft function 62.53 9.65 81 386100 3426 79354781
Malignant neoplasm of conjunctiva 62.35 9.65 19 386162 36 79358171
Lymphocele 62.08 9.65 57 386124 1624 79356583
Oropharyngeal pain 62.04 9.65 295 385886 109058 79249149
Hepatic enzyme increased 61.94 9.65 575 385606 182035 79176172
Meningitis bacterial 61.53 9.65 71 386110 2661 79355546
Sinus congestion 61.49 9.65 11 386170 19885 79338322
Focal segmental glomerulosclerosis 61.25 9.65 78 386103 3243 79354964
Bone tuberculosis 61.20 9.65 37 386144 543 79357664
Immune reconstitution inflammatory syndrome 60.95 9.65 176 386005 13665 79344542
Liver abscess 60.85 9.65 107 386074 5947 79352260
Disseminated varicella zoster virus infection 60.73 9.65 38 386143 595 79357612
Flushing 60.06 9.65 222 385959 88046 79270161
Blood glucose decreased 59.81 9.65 26 386155 26208 79331999
Orthostatic hypotension 59.77 9.65 113 386068 56051 79302156
Drug eruption 59.74 9.65 391 385790 43544 79314663
Diffuse large B-cell lymphoma refractory 59.61 9.65 52 386129 1383 79356824
Haemolytic anaemia 59.55 9.65 206 385975 17614 79340593
Intraocular pressure increased 59.17 9.65 135 386046 9070 79349137
Hypofibrinogenaemia 59.06 9.65 60 386121 1942 79356265
Epstein-Barr virus associated lymphoma 58.91 9.65 46 386135 1043 79357164
Vomiting 58.77 9.65 2631 383550 663197 78695010
Actinic keratosis 58.43 9.65 105 386076 5937 79352270
Human polyomavirus infection 58.28 9.65 46 386135 1060 79357147
Gastroenteritis 58.28 9.65 322 385859 33760 79324447
Alternaria infection 58.13 9.65 38 386143 644 79357563
Drug withdrawal syndrome 57.51 9.65 50 386131 34668 79323539
Dermatophytosis 57.07 9.65 33 386148 444 79357763
Pneumonitis 56.96 9.65 496 385685 60364 79297843
Epistaxis 56.93 9.65 312 385869 111203 79247004
Blood pressure systolic abnormal 56.77 9.65 8 386173 17239 79340968
Heart rate irregular 56.68 9.65 45 386136 32634 79325573
Anhedonia 56.58 9.65 4 386177 14894 79343313
Retinal drusen 56.48 9.65 16 386165 20 79358187
Graft loss 56.30 9.65 44 386137 999 79357208
Body temperature decreased 56.09 9.65 44 386137 32101 79326106
Haemolytic uraemic syndrome 55.98 9.65 87 386094 4362 79353845
Varicella 55.88 9.65 70 386111 2862 79355345
Infective aneurysm 55.44 9.65 43 386138 965 79357242
Chest discomfort 55.26 9.65 416 385765 137628 79220579
Ocular hypertension 55.08 9.65 51 386130 1469 79356738
Lymphadenopathy 54.63 9.65 443 385738 52804 79305403
Graft versus host disease in skin 54.27 9.65 102 386079 5971 79352236
Gallbladder rupture 54.25 9.65 42 386139 940 79357267
Thrombocytopenia 54.03 9.65 1674 384507 263585 79094622
Head injury 53.65 9.65 61 386120 37308 79320899
Oesophageal perforation 53.65 9.65 51 386130 1520 79356687
Cutaneous tuberculosis 53.58 9.65 25 386156 208 79357999
Sinus disorder 53.26 9.65 21 386160 22443 79335764
Seizure 53.25 9.65 621 385560 188213 79169994
Gestational diabetes 52.92 9.65 103 386078 6190 79352017
Gastroenteritis norovirus 52.68 9.65 70 386111 3036 79355171
Urosepsis 52.66 9.65 261 385920 26234 79331973
Viral vasculitis 52.66 9.65 22 386159 136 79358071
Inflammatory marker increased 52.64 9.65 142 386039 10598 79347609
Coronary artery disease 52.62 9.65 153 386028 65321 79292886
Cytomegalovirus gastroenteritis 52.60 9.65 31 386150 433 79357774
Tuberculous pleurisy 52.60 9.65 35 386146 612 79357595
Cytomegalovirus gastritis 52.54 9.65 31 386150 434 79357773
Sedation complication 52.20 9.65 7 386174 15662 79342545
Necrotising fasciitis 52.07 9.65 100 386081 5950 79352257
Pyoderma gangrenosum 51.89 9.65 81 386100 4077 79354130
Endophthalmitis 51.38 9.65 103 386078 6325 79351882
Hot flush 51.17 9.65 119 386062 54758 79303449
Ileal ulcer 51.12 9.65 43 386138 1087 79357120
Meningitis listeria 51.10 9.65 42 386139 1027 79357180
Cytomegalovirus hepatitis 51.04 9.65 37 386144 747 79357460
Concomitant disease aggravated 50.97 9.65 160 386021 13007 79345200
Systemic lupus erythematosus 50.94 9.65 360 385821 120789 79237418
Aspartate aminotransferase increased 50.90 9.65 949 385232 137692 79220515
Blood pressure diastolic abnormal 50.63 9.65 15 386166 19187 79339020
Maternal exposure during pregnancy 50.61 9.65 936 385245 135602 79222605
Cardiac arrest 50.07 9.65 562 385619 171534 79186673
Chest pain 50.00 9.65 1015 385166 281289 79076918
Basal cell carcinoma 49.83 9.65 331 385850 37044 79321163
Erythema multiforme 49.68 9.65 193 385988 17458 79340749
Hypersomnia 49.36 9.65 25 386156 23061 79335146
Toxoplasmosis 49.20 9.65 63 386118 2634 79355573
Human herpesvirus 6 infection 48.99 9.65 91 386090 5279 79352928
Epstein-Barr virus test positive 48.78 9.65 42 386139 1097 79357110
Dysgeusia 48.63 9.65 130 386051 57047 79301160
Graft versus host disease in gastrointestinal tract 48.62 9.65 100 386081 6256 79351951
Lactic acidosis 48.50 9.65 176 386005 70183 79288024
Large intestinal ulcer 48.50 9.65 85 386096 4712 79353495
International normalised ratio increased 48.38 9.65 228 385953 84493 79273714
Amoebic colitis 48.31 9.65 19 386162 98 79358109
Hepatosplenomegaly 48.22 9.65 97 386084 5972 79352235
Intestinal tuberculosis 48.14 9.65 23 386158 203 79358004
Mobility decreased 48.04 9.65 370 385811 121805 79236402
Skin ulcer 47.94 9.65 436 385745 53714 79304493
Cerebral aspergillosis 47.91 9.65 51 386130 1745 79356462
Pulmonary cavitation 47.71 9.65 49 386132 1607 79356600
Feeling hot 47.70 9.65 140 386041 59594 79298613
Pericarditis 47.70 9.65 302 385879 103934 79254273
Pyelonephritis acute 47.54 9.65 96 386085 5927 79352280
Empyema 47.49 9.65 79 386102 4197 79354010
Anogenital warts 47.40 9.65 38 386143 896 79357311
Neisseria infection 47.37 9.65 21 386160 153 79358054
Cytomegalovirus gastrointestinal infection 47.28 9.65 30 386151 482 79357725
Feeling jittery 47.22 9.65 4 386177 12837 79345370
Tonsillitis 47.14 9.65 102 386079 6612 79351595
Retinal haemorrhage 46.84 9.65 115 386066 8102 79350105
Dyskinesia 46.84 9.65 91 386090 44682 79313525
Lymph node tuberculosis 46.73 9.65 39 386142 975 79357232
Sleep apnoea syndrome 46.68 9.65 65 386116 36413 79321794
Psoas abscess 46.63 9.65 39 386142 978 79357229
Glomerulonephritis membranoproliferative 46.59 9.65 32 386149 591 79357616
Intensive care unit acquired weakness 46.53 9.65 52 386129 1881 79356326
Rheumatoid factor positive 46.52 9.65 142 386039 59697 79298510
Procedural pain 46.44 9.65 27 386154 23057 79335150
Plasma cell myeloma 46.13 9.65 120 386061 53139 79305068
Sleep disorder due to a general medical condition 46.11 9.65 7 386174 14270 79343937
Pulmonary alveolar haemorrhage 46 9.65 141 386040 11316 79346891
Haemorrhage subcutaneous 45.78 9.65 83 386098 4726 79353481
Sneezing 45.68 9.65 19 386162 19664 79338543
Myasthenia gravis crisis 45.63 9.65 40 386141 1071 79357136
Injection site rash 45.60 9.65 15 386166 17939 79340268
Lemierre syndrome 45.55 9.65 20 386161 142 79358065
Polyomavirus test positive 45.49 9.65 22 386159 200 79358007
Amnesia 45.29 9.65 155 386026 62902 79295305
Pseudomembranous colitis 45.24 9.65 88 386093 5286 79352921
Urticaria 45.17 9.65 628 385553 184573 79173634
Lumbar vertebral fracture 45.16 9.65 103 386078 6919 79351288
Diarrhoea haemorrhagic 45.11 9.65 154 386027 13080 79345127
Gallbladder disorder 44.36 9.65 19 386162 19321 79338886
Musculoskeletal chest pain 44.35 9.65 33 386148 24731 79333476
Meningitis 44.29 9.65 124 386057 9458 79348749
Keratitis 44.24 9.65 77 386104 4245 79353962
Microsporidia infection 44.20 9.65 37 386144 929 79357278
Adenoviral haemorrhagic cystitis 44.13 9.65 29 386152 496 79357711
Syncope 43.94 9.65 608 385573 178841 79179366
Respiratory tract congestion 43.59 9.65 21 386160 19933 79338274
Abdominal distension 43.53 9.65 370 385811 119280 79238927
Blood calcium decreased 43.48 9.65 54 386127 31765 79326442
Adenoviral hepatitis 43.44 9.65 36 386145 891 79357316
Myositis 43.33 9.65 196 385985 18972 79339235
Placenta accreta 43.32 9.65 21 386160 192 79358015
Gastric ulcer 43.25 9.65 297 385884 33608 79324599
Ecthyma 43.22 9.65 33 386148 723 79357484
Disease progression 43.14 9.65 1184 384997 183178 79175029
B-cell lymphoma recurrent 43.08 9.65 37 386144 963 79357244
Hydronephrosis 42.89 9.65 183 385998 17271 79340936
Trichosporon infection 42.83 9.65 37 386144 971 79357236
Cytopenia 42.82 9.65 204 385977 20179 79338028
Limb injury 42.61 9.65 48 386133 29480 79328727
Nephrolithiasis 42.48 9.65 125 386056 53166 79305041
Cytomegalovirus gastrointestinal ulcer 42.40 9.65 15 386166 54 79358153
Rheumatoid arthritis 42.33 9.65 732 385449 207738 79150469
Device dislocation 42.30 9.65 38 386143 25932 79332275
Rash 42.29 9.65 2330 383851 576028 78782179
T-cell lymphoma 42.04 9.65 41 386140 1262 79356945
Hernia 42.03 9.65 15 386166 17044 79341163
Keratitis bacterial 41.90 9.65 19 386162 147 79358060
Lung transplant rejection 41.77 9.65 44 386137 1487 79356720
Limb discomfort 41.58 9.65 59 386122 32791 79325416
Arthritis 41.45 9.65 356 385825 114524 79243683
Histoplasmosis disseminated 41.41 9.65 54 386127 2299 79355908
Infusion site pain 41.37 9.65 9 386172 14167 79344040
Malaise 41.07 9.65 1946 384235 487923 78870284
Sleep disorder due to general medical condition, insomnia type 40.97 9.65 94 386087 43462 79314745
Herpes zoster meningoencephalitis 40.85 9.65 32 386149 729 79357478
Peripheral T-cell lymphoma unspecified stage IV 40.66 9.65 13 386168 31 79358176
Underdose 40.53 9.65 61 386120 33090 79325117
Fungal skin infection 40.45 9.65 90 386091 5946 79352261
Enteritis infectious 40.23 9.65 64 386117 3274 79354933
Ill-defined disorder 40.18 9.65 173 386008 65702 79292505
Cognitive disorder 40.03 9.65 188 385993 69738 79288469
Joint injury 39.94 9.65 56 386125 31279 79326928
IgA nephropathy 39.90 9.65 46 386135 1722 79356485
Sleep disorder 39.84 9.65 247 385934 85430 79272777
Respiratory depression 39.78 9.65 45 386136 27585 79330622
Glucose tolerance impaired 39.74 9.65 107 386074 7977 79350230
Aortic dissection 39.67 9.65 72 386109 4103 79354104
Extrapyramidal disorder 39.62 9.65 31 386150 22648 79335559
Immune thrombocytopenia 39.46 9.65 181 386000 17624 79340583
Muscle injury 39.37 9.65 113 386068 48448 79309759
Visual acuity reduced 39.30 9.65 261 385920 29208 79328999
Stem cell transplant 39.23 9.65 67 386114 3637 79354570
Multiple allergies 39.18 9.65 3 386178 10457 79347750
Myelopathy 39.16 9.65 76 386105 4557 79353650
Skin striae 39.09 9.65 47 386134 1841 79356366
Viral load increased 39.00 9.65 59 386122 2889 79355318
Acute abdomen 38.99 9.65 61 386120 3076 79355131
Pathogen resistance 38.89 9.65 155 386026 14187 79344020
Acute graft versus host disease in intestine 38.79 9.65 70 386111 3971 79354236
Drug level increased 38.60 9.65 326 385855 39325 79318882
Cardiac failure 38.39 9.65 1002 385179 153840 79204367
Obstructive airways disorder 38.35 9.65 58 386123 31401 79326806
Mycotic endophthalmitis 38.34 9.65 19 386162 183 79358024
Escherichia sepsis 38.25 9.65 109 386072 8399 79349808
Human T-cell lymphotropic virus type I infection 38.19 9.65 15 386166 77 79358130
Influenza 38.18 9.65 422 385759 129184 79229023
Intussusception 38.10 9.65 37 386144 1133 79357074
Glomerulonephritis membranous 38.09 9.65 43 386138 1573 79356634
Escherichia urinary tract infection 37.96 9.65 150 386031 13675 79344532
Rhabdomyolysis 37.93 9.65 318 385863 102813 79255394
Hepatitis 37.91 9.65 425 385756 55302 79302905
Device malfunction 37.88 9.65 29 386152 21419 79336788
Infective spondylitis 37.49 9.65 26 386155 488 79357719
Bronchopleural fistula 37.42 9.65 29 386152 650 79357557
Ileus paralytic 37.33 9.65 117 386064 9503 79348704
Therapeutic response shortened 37.32 9.65 15 386166 15848 79342359
Interleukin-2 receptor increased 37.30 9.65 20 386161 230 79357977
Mediastinitis 37.29 9.65 32 386149 832 79357375
Gastritis bacterial 37.15 9.65 23 386158 353 79357854
Meningoencephalitis herpetic 37.13 9.65 47 386134 1942 79356265
Plasmablastic lymphoma 36.90 9.65 26 386155 501 79357706
Steroid dependence 36.74 9.65 54 386127 2576 79355631
Bronchiectasis 36.61 9.65 209 385972 22177 79336030
Herpes zoster meningitis 36.54 9.65 18 386163 171 79358036
Escherichia bacteraemia 36.52 9.65 91 386090 6471 79351736
Dengue fever 36.43 9.65 32 386149 859 79357348
Jaw operation 36.38 9.65 31 386150 798 79357409
Squamous cell carcinoma 36.26 9.65 161 386020 15461 79342746
Trichophytic granuloma 36.08 9.65 13 386168 50 79358157
Abscess 36.06 9.65 212 385969 22739 79335468
Leukoencephalopathy 36.05 9.65 102 386079 7827 79350380
Therapy non-responder 36.03 9.65 638 385543 91667 79266540
Crying 36.02 9.65 35 386146 23008 79335199
Blastomycosis 35.95 9.65 29 386152 690 79357517
Neuropsychiatric lupus 35.83 9.65 18 386163 179 79358028
Restless legs syndrome 35.69 9.65 27 386154 20065 79338142
Akathisia 35.62 9.65 10 386171 13249 79344958
Cardiac valve vegetation 35.58 9.65 32 386149 887 79357320
Pouchitis 35.48 9.65 33 386148 956 79357251
Rhinocerebral mucormycosis 35.47 9.65 34 386147 1024 79357183
Post herpetic neuralgia 35.45 9.65 53 386128 2568 79355639
Miosis 35.44 9.65 16 386165 15773 79342434
Meningitis tuberculous 35.34 9.65 36 386145 1169 79357038
Infective tenosynovitis 35.28 9.65 23 386158 388 79357819
Skin erosion 35.26 9.65 71 386110 4374 79353833
Central obesity 35.10 9.65 43 386138 1718 79356489
Colitis 35.07 9.65 524 385657 72783 79285424
Pneumonia pseudomonal 35.06 9.65 84 386097 5827 79352380
Pancreatic steatosis 35.03 9.65 35 386146 1110 79357097
Haematocrit decreased 35.00 9.65 165 386016 61147 79297060
Acute graft versus host disease in liver 34.98 9.65 45 386136 1890 79356317
Middle insomnia 34.96 9.65 17 386164 16052 79342155
Peliosis hepatis 34.93 9.65 16 386165 127 79358080
Injection site warmth 34.84 9.65 14 386167 14793 79343414
Parvovirus infection 34.76 9.65 28 386153 665 79357542
Renal abscess 34.53 9.65 34 386147 1059 79357148
Purpura 34.40 9.65 186 385995 19341 79338866
Lymphoplasmacytoid lymphoma/immunocytoma 34.40 9.65 12 386169 41 79358166
Bone erosion 34.33 9.65 22 386159 17825 79340382
Thrombosis 34.33 9.65 252 385929 83848 79274359
Cytomegalovirus duodenitis 34.28 9.65 14 386167 81 79358126
Chronic inflammatory demyelinating polyradiculoneuropathy 34.02 9.65 35 386146 1150 79357057
Fungal infection 33.88 9.65 330 385851 41418 79316789
Injection site urticaria 33.85 9.65 10 386171 12816 79345391
Autoimmune neutropenia 33.85 9.65 26 386155 575 79357632
Cholangitis 33.78 9.65 137 386044 12639 79345568
Corneal lesion 33.71 9.65 13 386168 63 79358144
Injury 33.70 9.65 228 385953 77268 79280939
Fear 33.67 9.65 34 386147 21952 79336255
Hypoglycaemia 33.53 9.65 322 385859 101272 79256935
Eczema herpeticum 33.41 9.65 20 386161 288 79357919
Disseminated trichosporonosis 33.41 9.65 16 386165 142 79358065
Hydrocephalus 33.40 9.65 107 386074 8793 79349414
Acute myeloid leukaemia 33.35 9.65 260 385921 30625 79327582
Renal tubular atrophy 33.30 9.65 43 386138 1813 79356394
Hypopyon 33.28 9.65 34 386147 1108 79357099
Pancreatitis acute 33.16 9.65 377 385804 49227 79308980
Skin mass 33.09 9.65 100 386081 7963 79350244
Surgery 33.07 9.65 68 386113 32698 79325509
Gastroenteritis viral 33.04 9.65 43 386138 24788 79333419
Impaired work ability 33.02 9.65 28 386153 19653 79338554
Glomerulonephritis proliferative 33.00 9.65 22 386159 386 79357821
Torsade de pointes 32.99 9.65 27 386154 19285 79338922
Gastroenteritis sapovirus 32.94 9.65 16 386165 147 79358060
Bulbar palsy 32.90 9.65 19 386162 255 79357952
Enterobacter infection 32.82 9.65 70 386111 4492 79353715
Jaundice 32.80 9.65 399 385782 52950 79305257
Pulmonary mucormycosis 32.71 9.65 34 386147 1131 79357076
Pneumonia pneumococcal 32.64 9.65 65 386116 3972 79354235
Autoimmune haemolytic anaemia 32.60 9.65 102 386079 8278 79349929
Bronchitis 32.56 9.65 441 385740 130203 79228004
Premature labour 32.52 9.65 102 386079 8288 79349919
Pneumococcal infection 32.52 9.65 31 386150 927 79357280
Nocardia sepsis 32.46 9.65 10 386171 20 79358187
Hypersensitivity pneumonitis 32.42 9.65 62 386119 3677 79354530
Adrenal atrophy 32.37 9.65 12 386169 51 79358156
Thymoma 32.27 9.65 19 386162 265 79357942
Blood pressure diastolic increased 32.23 9.65 15 386166 14527 79343680
Iron deficiency anaemia 32.22 9.65 224 385957 25448 79332759
Osteoarthritis 32.20 9.65 269 385912 87040 79271167
Exostosis 32.13 9.65 21 386160 16837 79341370
Gastroenteritis adenovirus 31.92 9.65 21 386160 360 79357847
Osteomyelitis 31.88 9.65 270 385911 32595 79325612
Extranodal marginal zone B-cell lymphoma (MALT type) 31.86 9.65 25 386156 571 79357636
Idiopathic pulmonary fibrosis 31.73 9.65 66 386115 4162 79354045
Encapsulating peritoneal sclerosis 31.71 9.65 29 386152 822 79357385
Psoriatic arthropathy 31.70 9.65 234 385947 77765 79280442
Humoral immune defect 31.67 9.65 22 386159 414 79357793
Labelled drug-drug interaction medication error 31.66 9.65 236 385945 27414 79330793
Acute hepatitis B 31.66 9.65 23 386158 466 79357741
Retching 31.64 9.65 23 386158 17444 79340763
Soft tissue mass 31.61 9.65 35 386146 1253 79356954
Mycoplasma infection 31.59 9.65 28 386153 761 79357446
Splenomegaly 31.51 9.65 190 385991 20564 79337643
Skin discolouration 31.45 9.65 98 386083 40936 79317271
Cutaneous T-cell lymphoma 31.45 9.65 51 386130 2652 79355555
Renal graft infection 31.43 9.65 24 386157 526 79357681
Wound infection pseudomonas 31.37 9.65 39 386142 1582 79356625
Needle issue 31.34 9.65 12 386169 13056 79345151
Hypervolaemia 31.30 9.65 104 386077 42586 79315621
Paradoxical drug reaction 31.29 9.65 91 386090 7094 79351113
Normal newborn 31.21 9.65 90 386091 6982 79351225
Blood alkaline phosphatase increased 31.21 9.65 457 385724 63207 79295000
Dry mouth 31.20 9.65 274 385907 87745 79270462
Malacoplakia gastrointestinal 31.18 9.65 16 386165 167 79358040
Premature rupture of membranes 31.10 9.65 64 386117 4005 79354202
Meningoencephalitis viral 31.09 9.65 22 386159 427 79357780
Mononeuropathy multiplex 31.05 9.65 22 386159 428 79357779
Intervertebral disc degeneration 31.00 9.65 19 386162 15766 79342441
Hip fracture 30.91 9.65 64 386117 30697 79327510
Hypocomplementaemia 30.87 9.65 17 386164 207 79358000
Adrenocortical insufficiency acute 30.87 9.65 54 386127 2989 79355218
T-cell lymphoma stage IV 30.86 9.65 15 386166 138 79358069
Lung adenocarcinoma 30.85 9.65 96 386085 7768 79350439
Papilloma viral infection 30.84 9.65 40 386141 1694 79356513
Upper limb fracture 30.84 9.65 25 386156 17942 79340265
Atypical pneumonia 30.80 9.65 86 386095 6550 79351657
Dysphonia 30.76 9.65 156 386025 56716 79301491
Arterial haemorrhage 30.73 9.65 49 386132 2512 79355695
Central nervous system vasculitis 30.72 9.65 36 386145 1372 79356835
Vision blurred 30.72 9.65 346 385835 105552 79252655
Hepatitis fulminant 30.69 9.65 91 386090 7171 79351036
Polyneuropathy 30.47 9.65 211 385970 23940 79334267
Adverse event 30.43 9.65 169 386012 60045 79298162
Gastric disorder 30.42 9.65 87 386094 37346 79320861
Aggression 30.36 9.65 135 386046 50823 79307384
Complications of transplanted liver 30.15 9.65 21 386160 397 79357810
Immunodeficiency common variable 30.14 9.65 20 386161 348 79357859
Renal tubular injury 30.13 9.65 37 386144 1482 79356725
Pneumonia acinetobacter 30.07 9.65 16 386165 181 79358026
Septic pulmonary embolism 30.06 9.65 14 386167 116 79358091
Anaplastic large-cell lymphoma 30.04 9.65 17 386164 219 79357988
Rash pruritic 30.03 9.65 213 385968 71416 79286791
Complications of transplanted lung 30.02 9.65 22 386159 452 79357755
Diverticular perforation 29.98 9.65 79 386102 5814 79352393
Anaphylactoid reaction 29.98 9.65 75 386106 5347 79352860
Hepatitis viral 29.93 9.65 31 386150 1027 79357180
Product storage error 29.87 9.65 21 386160 16205 79342002
Altered state of consciousness 29.72 9.65 334 385847 43488 79314719
Central nervous system infection 29.70 9.65 35 386146 1342 79356865
Calciphylaxis 29.65 9.65 60 386121 3710 79354497
Gingival hypertrophy 29.62 9.65 54 386127 3088 79355119
Histoplasmosis 29.41 9.65 46 386135 2319 79355888
Primary biliary cholangitis 29.41 9.65 32 386149 1123 79357084
Necrosis 29.37 9.65 107 386074 9386 79348821
Xanthogranuloma 29.30 9.65 12 386169 70 79358137
Malacoplakia vesicae 29.30 9.65 12 386169 70 79358137
Pustular psoriasis 29.26 9.65 69 386112 4737 79353470
Hospice care 29.24 9.65 7 386174 10317 79347890
Eye infection toxoplasmal 29.18 9.65 23 386158 529 79357678
Abdominal tenderness 29.13 9.65 115 386066 10479 79347728
Fusarium infection 29.11 9.65 40 386141 1792 79356415
Gastric perforation 29.11 9.65 62 386119 3975 79354232
Intervertebral discitis 29.06 9.65 69 386112 4759 79353448
Eye abscess 29.02 9.65 19 386162 323 79357884
Cardiac myxoma 28.97 9.65 14 386167 127 79358080
Blood immunoglobulin G decreased 28.91 9.65 56 386125 3353 79354854
Erosive duodenitis 28.90 9.65 43 386138 2074 79356133
Leishmaniasis 28.90 9.65 20 386161 374 79357833
Enterovesical fistula 28.80 9.65 32 386149 1150 79357057
Muscle spasticity 28.77 9.65 37 386144 21438 79336769
Uveitis 28.77 9.65 159 386022 16671 79341536
Pelvic deformity 28.75 9.65 12 386169 74 79358133
Shock 28.67 9.65 330 385851 43218 79314989
Poor quality sleep 28.57 9.65 41 386140 22681 79335526
IIIrd nerve paralysis 28.56 9.65 32 386149 1161 79357046
Palpitations 28.53 9.65 436 385745 126174 79232033
Neutropenic colitis 28.52 9.65 76 386105 5631 79352576
Acute hepatic failure 28.47 9.65 246 385935 29867 79328340
Chronic myeloid leukaemia 28.44 9.65 58 386123 3606 79354601
Staphylococcal bacteraemia 28.42 9.65 126 386055 12092 79346115
Ascites 28.33 9.65 519 385662 75043 79283164
Infertility 28.31 9.65 25 386156 676 79357531
Morganella infection 28.30 9.65 31 386150 1096 79357111
Pneumothorax spontaneous 28.17 9.65 35 386146 1419 79356788
Stevens-Johnson syndrome 28.16 9.65 302 385879 38864 79319343
Colon cancer 28.11 9.65 142 386039 14381 79343826
Condition aggravated 28.09 9.65 2804 383377 498320 78859887
Mycobacterium kansasii infection 28.03 9.65 19 386162 343 79357864
Accidental overdose 27.95 9.65 98 386083 39483 79318724
Diffuse alveolar damage 27.92 9.65 57 386124 3547 79354660
Poor venous access 27.87 9.65 28 386153 18121 79340086
Tooth infection 27.85 9.65 30 386151 18802 79339405
Abdominal pain upper 27.84 9.65 848 385333 222971 79135236
Exposed bone in jaw 27.83 9.65 58 386123 3662 79354545
Encephalitis viral 27.78 9.65 47 386134 2532 79355675
Ureteric stenosis 27.76 9.65 34 386147 1358 79356849
Product complaint 27.74 9.65 15 386166 13334 79344873
Ophthalmic herpes zoster 27.71 9.65 48 386133 2636 79355571
Musculoskeletal disorder 27.66 9.65 38 386143 21410 79336797
Skin laceration 27.65 9.65 62 386119 28900 79329307
Disseminated varicella zoster vaccine virus infection 27.58 9.65 13 386168 111 79358096
Mantle cell lymphoma refractory 27.58 9.65 13 386168 111 79358096
Chromoblastomycosis 27.48 9.65 12 386169 84 79358123
Foetal growth restriction 27.45 9.65 42 386139 2077 79356130
Postoperative wound infection 27.43 9.65 130 386051 12831 79345376
Herpes zoster reactivation 27.35 9.65 15 386166 181 79358026
Circulatory collapse 27.34 9.65 291 385890 37377 79320830
Herpes simplex test positive 27.33 9.65 20 386161 410 79357797
Pneumonia haemophilus 27.31 9.65 31 386150 1141 79357066
Pulmonary air leakage 27.31 9.65 16 386165 221 79357986
Molluscum contagiosum 27.20 9.65 21 386160 468 79357739
Sexual dysfunction 27.01 9.65 3 386178 7760 79350447
Shock haemorrhagic 26.95 9.65 178 386003 19882 79338325
Cryptococcal cutaneous infection 26.93 9.65 15 386166 187 79358020
Streptococcal infection 26.87 9.65 99 386082 8731 79349476
Superinfection bacterial 26.86 9.65 35 386146 1489 79356718
Complication associated with device 26.86 9.65 27 386154 17469 79340738
Cerebral venous thrombosis 26.82 9.65 48 386133 2705 79355502
Acanthosis 26.82 9.65 21 386160 478 79357729
Microangiopathic haemolytic anaemia 26.81 9.65 35 386146 1492 79356715
Presyncope 26.79 9.65 105 386076 40949 79317258
Neuromyelitis optica spectrum disorder 26.76 9.65 29 386152 1013 79357194
Musculoskeletal discomfort 26.75 9.65 34 386147 19801 79338406
Type 1 diabetes mellitus 26.71 9.65 84 386097 6835 79351372
Thyroiditis subacute 26.70 9.65 18 386163 322 79357885
Laryngitis 26.69 9.65 23 386158 16016 79342191
Duodenal perforation 26.67 9.65 42 386139 2130 79356077
Arterial thrombosis 26.54 9.65 47 386134 2627 79355580
Oliguria 26.50 9.65 152 386029 16157 79342050
Rectal perforation 26.47 9.65 27 386154 878 79357329
Product monitoring error 26.39 9.65 99 386082 8807 79349400
Respiratory alkalosis 26.37 9.65 62 386119 4249 79353958
Back injury 26.36 9.65 9 386172 10514 79347693
Malacoplakia 26.32 9.65 23 386158 613 79357594
Wound dehiscence 26.32 9.65 81 386100 6514 79351693
Human herpesvirus 6 infection reactivation 26.26 9.65 22 386159 553 79357654
Creatinine renal clearance decreased 26.23 9.65 32 386149 18970 79339237
Glomerulonephritis rapidly progressive 26.22 9.65 36 386145 1612 79356595
Nephritis 26.20 9.65 61 386120 4153 79354054
Atypical fracture 26.19 9.65 24 386157 682 79357525
Hyperglycaemic hyperosmolar nonketotic syndrome 26.18 9.65 43 386138 2260 79355947
Secondary adrenocortical insufficiency 26.16 9.65 50 386131 2964 79355243
Infection masked 26.08 9.65 13 386168 127 79358080
Guillain-Barre syndrome 26.03 9.65 99 386082 8866 79349341
Product substitution issue 26.01 9.65 36 386145 20220 79337987
Tooth disorder 26.00 9.65 55 386126 26178 79332029
Cell marker increased 25.86 9.65 23 386158 628 79357579
Hyperplasia 25.83 9.65 31 386150 1212 79356995
Hepatic amoebiasis 25.81 9.65 12 386169 99 79358108
Abscess fungal 25.77 9.65 18 386163 342 79357865
Mycobacterium fortuitum infection 25.74 9.65 15 386166 205 79358002
Lepromatous leprosy 25.68 9.65 11 386170 73 79358134
Adverse drug reaction 25.65 9.65 202 385979 66190 79292017
Back disorder 25.57 9.65 12 386169 11566 79346641
Seasonal allergy 25.55 9.65 25 386156 16381 79341826
Drug dependence 25.52 9.65 106 386075 40663 79317544
Cutaneous leishmaniasis 25.51 9.65 17 386164 298 79357909
Sudden hearing loss 25.47 9.65 39 386142 1930 79356277
White blood cell count increased 25.38 9.65 505 385676 74128 79284079
Neonatal hypoacusis 25.34 9.65 8 386173 18 79358189
Blood test abnormal 25.32 9.65 29 386152 17681 79340526
Atypical haemolytic uraemic syndrome 25.25 9.65 28 386153 1004 79357203
Biopsy kidney abnormal 25.24 9.65 14 386167 173 79358034
Granuloma 25.23 9.65 93 386088 8204 79350003
Legionella infection 25.23 9.65 25 386156 785 79357422
Keratitis fungal 25.08 9.65 17 386164 307 79357900
Renal infarct 25.05 9.65 46 386135 2645 79355562
Glomerulosclerosis 25.00 9.65 29 386152 1093 79357114
Myelitis 25.00 9.65 43 386138 2348 79355859
Knee arthroplasty 24.91 9.65 116 386065 43132 79315075
Herpes virus infection 24.88 9.65 83 386098 6966 79351241
Exophthalmos 24.86 9.65 36 386145 1694 79356513
Blood creatinine increased 24.86 9.65 952 385229 154105 79204102
Lower respiratory tract infection 24.83 9.65 810 385371 128410 79229797
Carpal tunnel syndrome 24.78 9.65 35 386146 19493 79338714
Femoral neck fracture 24.78 9.65 105 386076 9879 79348328
Ulcerative keratitis 24.71 9.65 55 386126 3634 79354573
Coeliac disease 24.71 9.65 12 386169 11339 79346868
Evans syndrome 24.66 9.65 19 386162 422 79357785
Bursitis infective 24.64 9.65 31 386150 1273 79356934
Endocarditis enterococcal 24.59 9.65 13 386168 145 79358062
Pulmonary artery thrombosis 24.58 9.65 32 386149 1360 79356847
Cutaneous malacoplakia 24.54 9.65 12 386169 112 79358095
Meningoencephalitis bacterial 24.53 9.65 15 386166 225 79357982
Melaena 24.52 9.65 423 385758 60467 79297740
Epidural lipomatosis 24.50 9.65 30 386151 1198 79357009
Neuroendocrine carcinoma of the skin 24.49 9.65 31 386150 1281 79356926
Auditory neuropathy spectrum disorder 24.48 9.65 8 386173 21 79358186
Mesangioproliferative glomerulonephritis 24.45 9.65 12 386169 113 79358094
Amoebiasis 24.45 9.65 12 386169 113 79358094
Enterocolitis viral 24.35 9.65 18 386163 375 79357832
Giant cell arteritis 24.33 9.65 46 386135 2705 79355502
Herpes simplex viraemia 24.29 9.65 19 386162 432 79357775
Electrocardiogram QRS complex prolonged 24.28 9.65 11 386170 10822 79347385
Parotid abscess 24.18 9.65 7 386174 10 79358197
Joint tuberculosis 24.06 9.65 13 386168 152 79358055
Anuria 24.05 9.65 179 386002 20784 79337423
Ligament sprain 24.04 9.65 18 386163 13446 79344761
Concussion 24.03 9.65 8 386173 9495 79348712
Synovectomy 24.02 9.65 15 386166 234 79357973
Kidney fibrosis 24.02 9.65 53 386128 3482 79354725
Extradural abscess 24.01 9.65 33 386148 1479 79356728
Corynebacterium infection 24.01 9.65 31 386150 1307 79356900
Stenotrophomonas infection 23.88 9.65 55 386126 3718 79354489
Fungal test positive 23.87 9.65 28 386153 1068 79357139
Macular fibrosis 23.80 9.65 23 386158 700 79357507
Microsporum infection 23.78 9.65 9 386172 41 79358166
Pleocytosis 23.75 9.65 32 386149 1407 79356800
Sensitivity to weather change 23.70 9.65 5 386176 8042 79350165
Atypical mycobacterial pneumonia 23.70 9.65 13 386168 157 79358050
Chronic obstructive pulmonary disease 23.64 9.65 282 385899 85137 79273070
Leiomyosarcoma 23.63 9.65 17 386164 339 79357868
Retroperitoneal abscess 23.63 9.65 18 386163 393 79357814
Ophthalmic herpes simplex 23.61 9.65 23 386158 707 79357500
Skin lesion 23.61 9.65 308 385873 41536 79316671
Multiple sclerosis 23.55 9.65 45 386136 22237 79335970
Rectal ulcer 23.54 9.65 39 386142 2065 79356142
Systemic scleroderma 23.49 9.65 29 386152 1168 79357039
Retinal pigment epitheliopathy 23.45 9.65 19 386162 455 79357752
Tongue necrosis 23.44 9.65 9 386172 43 79358164
Hepatitis C RNA increased 23.43 9.65 18 386163 398 79357809
Pulmonary thrombosis 23.42 9.65 15 386166 12156 79346051
Still's disease 23.41 9.65 7 386174 12 79358195
Skin necrosis 23.40 9.65 159 386022 17928 79340279
Cataract subcapsular 23.39 9.65 26 386155 935 79357272
Perinephric abscess 23.27 9.65 15 386166 248 79357959
Ocular procedural complication 23.21 9.65 19 386162 462 79357745
Herpes simplex hepatitis 23.14 9.65 20 386161 525 79357682
Human herpesvirus 6 encephalitis 23.13 9.65 22 386159 656 79357551
Lymphocyte stimulation test positive 23.12 9.65 28 386153 1105 79357102
Substance abuse 23.11 9.65 11 386170 10515 79347692
Apnoea 23.11 9.65 14 386167 11690 79346517
Depressed level of consciousness 23.10 9.65 329 385852 96323 79261884
Subileus 23.09 9.65 70 386111 5584 79352623
Duodenal ulcer 23.06 9.65 147 386034 16222 79341985
Tracheobronchitis 22.99 9.65 38 386143 2008 79356199
Blood cholesterol increased 22.94 9.65 277 385904 83443 79274764
Duodenal ulcer repair 22.90 9.65 10 386171 70 79358137
Tachyarrhythmia 22.84 9.65 80 386101 6882 79351325
Systemic inflammatory response syndrome 22.83 9.65 113 386068 11352 79346855
Glomerulonephritis 22.79 9.65 51 386130 3382 79354825
Viral haemorrhagic cystitis 22.79 9.65 38 386143 2023 79356184
Malignant neoplasm progression 22.77 9.65 839 385342 135151 79223056
DNA antibody positive 22.72 9.65 16 386165 308 79357899
Bacillus infection 22.69 9.65 28 386153 1127 79357080
Pancreas transplant rejection 22.68 9.65 16 386165 309 79357898
Hepatitis C 22.66 9.65 116 386065 11809 79346398
Autoimmune hepatitis 22.66 9.65 115 386066 11668 79346539
Papillary renal cell carcinoma 22.66 9.65 15 386166 260 79357947
Cushing's syndrome 22.65 9.65 26 386155 969 79357238
Gene mutation 22.63 9.65 44 386137 2642 79355565
Blood urine present 22.52 9.65 43 386138 21254 79336953
Bone infarction 22.47 9.65 19 386162 484 79357723
Antiphospholipid syndrome 22.44 9.65 36 386145 1855 79356352
Pneumonia legionella 22.38 9.65 46 386135 2876 79355331
Gastrointestinal disorder 22.32 9.65 437 385744 121768 79236439
Pharyngitis streptococcal 22.32 9.65 12 386169 10702 79347505
Pulmonary sepsis 22.28 9.65 53 386128 3659 79354548
Cellulitis gangrenous 22.26 9.65 15 386166 268 79357939
Tuberculosis gastrointestinal 22.25 9.65 20 386161 554 79357653
Mouth ulceration 22.25 9.65 284 385897 38110 79320097
Laboratory test abnormal 22.20 9.65 66 386115 27982 79330225
Candida sepsis 22.20 9.65 42 386139 2471 79355736
Panic attack 22.18 9.65 53 386128 24163 79334044
Helicobacter infection 22.13 9.65 223 385958 69481 79288726
Reversible cerebral vasoconstriction syndrome 22.10 9.65 47 386134 3010 79355197
Large intestine infection 22.08 9.65 48 386133 3121 79355086
Chronic myelomonocytic leukaemia 22.06 9.65 24 386157 842 79357365
Continuous haemodiafiltration 22.06 9.65 37 386144 1979 79356228
Fibromyalgia 22.05 9.65 202 385979 64138 79294069
Bradyphrenia 22.04 9.65 12 386169 10628 79347579
Complement factor decreased 22.02 9.65 11 386170 108 79358099
Rhegmatogenous retinal detachment 21.97 9.65 13 386168 183 79358024
Metaphyseal corner fracture 21.96 9.65 8 386173 32 79358175
Anaemia 21.96 9.65 2469 383712 442546 78915661
Fungal sepsis 21.94 9.65 35 386146 1795 79356412
Infective pulmonary exacerbation of cystic fibrosis 21.91 9.65 18 386163 12833 79345374
Phaeohyphomycotic brain abscess 21.90 9.65 9 386172 53 79358154
Gastrointestinal necrosis 21.89 9.65 68 386113 5497 79352710
Serous retinal detachment 21.84 9.65 26 386155 1008 79357199
Haematuria 21.83 9.65 461 385720 68375 79289832
Salmonellosis 21.82 9.65 35 386146 1803 79356404
Foot deformity 21.81 9.65 53 386128 24021 79334186
Neutrophilic panniculitis 21.77 9.65 10 386171 80 79358127
Passenger lymphocyte syndrome 21.76 9.65 11 386170 111 79358096
Stress fracture 21.73 9.65 75 386106 6405 79351802
Prostate cancer metastatic 21.71 9.65 55 386126 3952 79354255
Macular pseudohole 21.68 9.65 5 386176 0 79358207
Polyglandular autoimmune syndrome type III 21.68 9.65 5 386176 0 79358207
Herpes zoster oticus 21.63 9.65 18 386163 448 79357759
Pulmonary necrosis 21.60 9.65 19 386162 511 79357696
Lung lobectomy 21.59 9.65 12 386169 149 79358058
Osteomyelitis fungal 21.56 9.65 15 386166 283 79357924
Chronic graft versus host disease in skin 21.53 9.65 32 386149 1542 79356665
Infusion site extravasation 21.53 9.65 11 386170 10097 79348110
Localised infection 21.52 9.65 101 386080 37474 79320733
Pulse absent 21.51 9.65 11 386170 10092 79348115
Myalgia 21.48 9.65 710 385471 184931 79173276
Cytomegalovirus mucocutaneous ulcer 21.45 9.65 10 386171 83 79358124
Product use issue 21.42 9.65 815 385366 209007 79149200
Device leakage 21.41 9.65 13 386168 10843 79347364
Mantle cell lymphoma recurrent 21.35 9.65 20 386161 585 79357622
Intentional dose omission 21.30 9.65 8 386173 8809 79349398
Blood lactate dehydrogenase 21.25 9.65 7 386174 19 79358188
Diffuse large B-cell lymphoma stage IV 21.24 9.65 19 386162 523 79357684
Monoclonal B-cell lymphocytosis 21.23 9.65 9 386172 58 79358149
Blood fibrinogen decreased 21.23 9.65 36 386145 1943 79356264
Encephalitis cytomegalovirus 21.19 9.65 27 386154 1123 79357084
Incorrect route of product administration 21.13 9.65 92 386089 34837 79323370
Corneal scar 21.12 9.65 15 386166 293 79357914
Osteomyelitis bacterial 21.10 9.65 18 386163 464 79357743
Vitritis 21.08 9.65 34 386147 1760 79356447
Renal tubular acidosis 21.05 9.65 51 386130 3563 79354644
Graft versus host disease in lung 21.04 9.65 24 386157 888 79357319
Uterine haematoma 20.99 9.65 7 386174 20 79358187
Mucinous adenocarcinoma of appendix 20.99 9.65 7 386174 20 79358187
Iris hypopigmentation 20.98 9.65 9 386172 60 79358147
Gastropleural fistula 20.98 9.65 9 386172 60 79358147
Blood phosphorus increased 20.96 9.65 12 386169 10335 79347872
Vascular pseudoaneurysm 20.95 9.65 50 386131 3460 79354747
Infected skin ulcer 20.90 9.65 49 386132 3352 79354855
Musculoskeletal pain 20.89 9.65 359 385822 101995 79256212
Femoral hernia incarcerated 20.87 9.65 23 386158 819 79357388
Immune-mediated enterocolitis 20.86 9.65 61 386120 4769 79353438
Proctocolectomy 20.85 9.65 12 386169 160 79358047
Granulomatous rosacea 20.81 9.65 13 386168 203 79358004
Prinzmetal angina 20.76 9.65 33 386148 1687 79356520
Erythema infectiosum 20.75 9.65 13 386168 204 79358003
Disseminated mycobacterium avium complex infection 20.75 9.65 13 386168 204 79358003
Cerebellar stroke 20.73 9.65 19 386162 540 79357667
Aspergilloma 20.71 9.65 20 386161 608 79357599
Hypochromic anaemia 20.71 9.65 43 386138 2708 79355499
Red cell fragmentation syndrome 20.61 9.65 9 386172 63 79358144
Corneal deposits 20.59 9.65 18 386163 480 79357727
Candida endophthalmitis 20.59 9.65 12 386169 164 79358043
Uterine perforation 20.57 9.65 3 386178 6300 79351907
Herpes simplex oesophagitis 20.56 9.65 16 386165 361 79357846
Rheumatoid vasculitis 20.53 9.65 18 386163 482 79357725
Transient ischaemic attack 20.51 9.65 160 386021 52535 79305672
Thoracic vertebral fracture 20.49 9.65 64 386117 5189 79353018
Hepatic atrophy 20.40 9.65 17 386164 424 79357783
Depressed mood 20.40 9.65 144 386037 48336 79309871
Red blood cell count decreased 20.40 9.65 179 386002 57334 79300873
Body height decreased 20.37 9.65 8 386173 8572 79349635
Nightmare 20.36 9.65 61 386120 25800 79332407
Enterovirus infection 20.34 9.65 35 386146 1912 79356295
Oral mucosa erosion 20.34 9.65 35 386146 1912 79356295
Pseudomonal sepsis 20.31 9.65 71 386110 6103 79352104
Frequent bowel movements 20.28 9.65 74 386107 29465 79328742
Graft versus host disease in liver 20.28 9.65 33 386148 1721 79356486
Endotoxic shock 20.27 9.65 7 386174 23 79358184
Intrauterine infection 20.25 9.65 9 386172 66 79358141
Eye infection staphylococcal 20.22 9.65 12 386169 170 79358037
Neuropathy peripheral 20.21 9.65 525 385656 140780 79217427
Thyroid disorder 20.19 9.65 23 386158 14056 79344151
Aortic valve stenosis 20.19 9.65 64 386117 5230 79352977
Lymphoma transformation 20.19 9.65 15 386166 315 79357892
Blast crisis in myelogenous leukaemia 20.19 9.65 23 386158 850 79357357
Diffuse panbronchiolitis 20.17 9.65 6 386175 10 79358197
Aortic aneurysm rupture 20.17 9.65 28 386153 1267 79356940
Dehiscence 20.16 9.65 12 386169 171 79358036
Septic encephalopathy 20.09 9.65 14 386167 265 79357942
Head deformity 20.07 9.65 8 386173 43 79358164
Respiratory tract infection fungal 20.06 9.65 27 386154 1186 79357021
Lymphatic fistula 20.01 9.65 22 386159 781 79357426
Hepatic cytolysis 20.00 9.65 66 386115 27085 79331122
Ureterolithiasis 20.00 9.65 52 386129 3796 79354411
Tubulointerstitial nephritis and uveitis syndrome 19.99 9.65 15 386166 320 79357887
Transaminases increased 19.96 9.65 357 385824 51386 79306821
Ageusia 19.95 9.65 31 386150 16601 79341606
Apoptosis 19.92 9.65 18 386163 502 79357705
Familial mediterranean fever 19.92 9.65 12 386169 175 79358032
Personality disorder 19.88 9.65 3 386178 6143 79352064
Kidney infection 19.88 9.65 48 386133 21803 79336404
Asteatosis 19.86 9.65 10 386171 100 79358107
Citrobacter infection 19.84 9.65 24 386157 946 79357261
Anal prolapse 19.81 9.65 9 386172 70 79358137
Central nervous system fungal infection 19.78 9.65 17 386164 443 79357764
Seroma 19.77 9.65 38 386143 2262 79355945
Leukaemic infiltration 19.76 9.65 11 386170 137 79358070
Hepatitis B DNA increased 19.75 9.65 22 386159 793 79357414
B-lymphocyte count decreased 19.71 9.65 29 386152 1385 79356822
Failure to thrive 19.69 9.65 17 386164 11827 79346380
Dermatophytosis of nail 19.68 9.65 12 386169 179 79358028
Superior sagittal sinus thrombosis 19.66 9.65 25 386156 1038 79357169
Eye infection fungal 19.66 9.65 18 386163 511 79357696
Tooth abscess 19.65 9.65 30 386151 16180 79342027
Poikiloderma 19.62 9.65 16 386165 387 79357820
Tularaemia 19.60 9.65 10 386171 103 79358104
Cholecystitis infective 19.59 9.65 44 386137 2925 79355282
Neoplasm skin 19.57 9.65 31 386150 1580 79356627
Sinus bradycardia 19.56 9.65 60 386121 25187 79333020
Erysipelas 19.55 9.65 104 386077 10746 79347461
Conjunctival oedema 19.49 9.65 26 386155 1132 79357075
Cyclosporidium infection 19.48 9.65 6 386175 12 79358195
Herpes zoster cutaneous disseminated 19.43 9.65 17 386164 454 79357753
Small cell lung cancer 19.36 9.65 43 386138 2837 79355370
Congenital coronary artery malformation 19.36 9.65 10 386171 106 79358101
Protothecosis 19.35 9.65 8 386173 48 79358159
Chronic eosinophilic rhinosinusitis 19.34 9.65 5 386176 3 79358204
Gastric cancer 19.33 9.65 99 386082 10080 79348127
Multimorbidity 19.32 9.65 29 386152 1410 79356797
C-reactive protein abnormal 19.23 9.65 146 386035 48221 79309986
Paraneoplastic pemphigus 19.22 9.65 11 386170 145 79358062
Inferior vena cava stenosis 19.21 9.65 8 386173 49 79358158
Lupus enteritis 19.21 9.65 8 386173 49 79358158
Chronic hepatitis 19.20 9.65 29 386152 1418 79356789
Megakaryocytes increased 19.19 9.65 10 386171 108 79358099
Glossopharyngeal nerve paralysis 19.16 9.65 6 386175 13 79358194
Infusion site erythema 19.12 9.65 11 386170 9449 79348758
Vogt-Koyanagi-Harada disease 19.12 9.65 13 386168 236 79357971
Symblepharon 19.12 9.65 12 386169 189 79358018
Therapy change 19.11 9.65 6 386175 7393 79350814
Bronchostenosis 19.10 9.65 20 386161 671 79357536
Bursitis infective staphylococcal 19.08 9.65 9 386172 77 79358130
Klebsiella sepsis 19.06 9.65 46 386135 3206 79355001
Impaired quality of life 19.05 9.65 25 386156 14361 79343846
Tardive dyskinesia 19.04 9.65 14 386167 10557 79347650
Cytomegalovirus nephritis 19.02 9.65 11 386170 148 79358059
Renal disorder 18.99 9.65 298 385883 41807 79316400
Orbital infection 18.98 9.65 9 386172 78 79358129
Coxsackie viral infection 18.94 9.65 8 386173 51 79358156
Meningomyelitis herpes 18.88 9.65 9 386172 79 79358128
Nerve injury 18.87 9.65 11 386170 9381 79348826
Henoch-Schonlein purpura 18.83 9.65 41 386140 2669 79355538
Drug level fluctuating 18.83 9.65 21 386160 758 79357449
Atrial fibrillation 18.82 9.65 775 385406 197111 79161096
Listeria encephalitis 18.80 9.65 14 386167 295 79357912
Tongue disorder 18.80 9.65 24 386157 13951 79344256
Ileal perforation 18.79 9.65 24 386157 1001 79357206
Disseminated strongyloidiasis 18.75 9.65 13 386168 244 79357963
Haematoma infection 18.74 9.65 30 386151 1543 79356664
Psychomotor hyperactivity 18.73 9.65 33 386148 16816 79341391
Gastric ulcer haemorrhage 18.71 9.65 90 386091 8937 79349270
Scrotal ulcer 18.71 9.65 16 386165 414 79357793
Periodontitis 18.68 9.65 56 386125 4440 79353767
Red cell distribution width increased 18.67 9.65 28 386153 15214 79342993
Increased tendency to bruise 18.67 9.65 14 386167 10450 79347757
Cow pox 18.65 9.65 7 386174 31 79358176
Actinomycosis 18.64 9.65 25 386156 1094 79357113
Diverticulum intestinal haemorrhagic 18.63 9.65 52 386129 3959 79354248
Purulent discharge 18.63 9.65 68 386113 5971 79352236
Muscle rigidity 18.63 9.65 43 386138 19839 79338368
Dry throat 18.60 9.65 7 386174 7699 79350508
Post procedural bile leak 18.58 9.65 16 386165 418 79357789
Renal cell carcinoma 18.57 9.65 72 386109 6506 79351701
Antithrombin III decreased 18.55 9.65 17 386164 483 79357724
Ankylosing spondylitis 18.55 9.65 19 386162 12186 79346021
H1N1 influenza 18.53 9.65 39 386142 2480 79355727
Necrotising colitis 18.51 9.65 24 386157 1016 79357191
Abdominal abscess 18.51 9.65 76 386105 7051 79351156
Rectal haemorrhage 18.49 9.65 259 385922 76041 79282166
Scleral disorder 18.48 9.65 12 386169 201 79358006
Dry eye 18.47 9.65 104 386077 36827 79321380
Smooth muscle cell neoplasm 18.39 9.65 23 386158 939 79357268
Epstein-Barr virus antibody positive 18.38 9.65 19 386162 628 79357579
Syringe issue 18.38 9.65 4 386177 6294 79351913
Infectious thyroiditis 18.36 9.65 10 386171 119 79358088
Product preparation error 18.35 9.65 3 386178 5790 79352417
Granulomatosis with polyangiitis 18.35 9.65 42 386139 2828 79355379
IVth nerve paralysis 18.34 9.65 11 386170 159 79358048
New onset diabetes after transplantation 18.34 9.65 11 386170 159 79358048
Haemorrhagic diathesis 18.34 9.65 68 386113 6016 79352191
Ureaplasma infection 18.33 9.65 24 386157 1026 79357181
Blood iron decreased 18.29 9.65 29 386152 15405 79342802
Metastases to lymph nodes 18.29 9.65 99 386082 10298 79347909
Deformity 18.26 9.65 12 386169 9593 79348614
Injection site discolouration 18.24 9.65 7 386174 7607 79350600
Lupus myocarditis 18.22 9.65 9 386172 86 79358121
Gastrosplenic fistula 18.21 9.65 10 386171 121 79358086
Chronic gastritis 18.17 9.65 52 386129 4016 79354191
Drug dose omission by device 18.17 9.65 4 386177 6246 79351961
Cough 18.15 9.65 1529 384652 365260 78992947
Septic arthritis staphylococcal 18.14 9.65 21 386160 790 79357417
Anti-platelet antibody positive 18.13 9.65 14 386167 312 79357895
Epstein-Barr virus antigen positive 18.13 9.65 9 386172 87 79358120
Gastroenteritis bacterial 18.11 9.65 16 386165 433 79357774
Leukoderma 18.10 9.65 11 386170 163 79358044
Hepatic artery thrombosis 18.10 9.65 14 386167 313 79357894
Hallucination 18.06 9.65 299 385882 85446 79272761
Ejection fraction decreased 18.05 9.65 96 386085 34481 79323726
Brain compression 18.04 9.65 18 386163 570 79357637
Sinusitis aspergillus 18.04 9.65 13 386168 260 79357947
Tinnitus 18.01 9.65 133 386048 44200 79314007
Haemolysis 18.01 9.65 115 386066 12697 79345510
Vertigo 18.01 9.65 231 385950 68851 79289356
Hypersensitivity vasculitis 18 9.65 74 386107 6869 79351338
Panniculitis 17.99 9.65 112 386069 12259 79345948
Acid fast bacilli infection 17.99 9.65 11 386170 165 79358042
Erythrophagocytosis 17.97 9.65 7 386174 35 79358172
Intestinal fistula 17.93 9.65 28 386153 1410 79356797
Device use error 17.91 9.65 6 386175 7095 79351112
Nail pigmentation 17.91 9.65 14 386167 318 79357889
Cryptosporidiosis infection 17.91 9.65 20 386161 723 79357484
Cystitis 17.88 9.65 166 386015 52566 79305641
Myeloproliferative neoplasm 17.88 9.65 23 386158 966 79357241
Microvillous inclusion disease 17.88 9.65 12 386169 213 79357994
Spinal fracture 17.87 9.65 149 386032 17905 79340302
Retroperitoneal neoplasm 17.81 9.65 7 386174 36 79358171
Neuralgia 17.81 9.65 92 386089 33292 79324915
Mycobacterium haemophilum infection 17.79 9.65 10 386171 127 79358080
Hormone-refractory prostate cancer 17.77 9.65 16 386165 444 79357763
Squamous cell carcinoma of the oral cavity 17.76 9.65 17 386164 511 79357696
Haemobilia 17.76 9.65 17 386164 511 79357696
Melanaemia 17.74 9.65 8 386173 61 79358146
Post transplant distal limb syndrome 17.73 9.65 18 386163 582 79357625
Disability 17.73 9.65 35 386146 17085 79341122
Urinary tract infection bacterial 17.69 9.65 70 386111 6386 79351821
Angioimmunoblastic T-cell lymphoma 17.66 9.65 16 386165 448 79357759
Cerebellar infarction 17.65 9.65 48 386133 3599 79354608
Ureteric obstruction 17.64 9.65 40 386141 2676 79355531
Blood pressure ambulatory increased 17.63 9.65 8 386173 62 79358145
Nosocomial infection 17.62 9.65 41 386140 2791 79355416
Bacterial vulvovaginitis 17.61 9.65 18 386163 587 79357620
Eye irritation 17.60 9.65 47 386134 20634 79337573
Biliary anastomosis complication 17.59 9.65 11 386170 172 79358035
Stress ulcer 17.59 9.65 10 386171 130 79358077
Fungal abscess central nervous system 17.52 9.65 10 386171 131 79358076
Burkholderia pseudomallei infection 17.52 9.65 8 386173 63 79358144
Ileal stenosis 17.49 9.65 37 386144 2361 79355846
Deafness neurosensory 17.48 9.65 73 386108 6825 79351382
Corneal perforation 17.47 9.65 20 386161 743 79357464
Device occlusion 17.44 9.65 19 386162 11847 79346360
Oesophageal fibrosis 17.43 9.65 11 386170 175 79358032
Mucosal ulceration 17.41 9.65 32 386149 1841 79356366
Irritability 17.41 9.65 122 386059 41022 79317185
Nuchal rigidity 17.39 9.65 24 386157 1080 79357127
Prostatic abscess 17.38 9.65 15 386166 393 79357814
Vitamin D decreased 17.36 9.65 13 386168 9712 79348495
Renal adenoma 17.36 9.65 7 386174 39 79358168
Essential hypertension 17.35 9.65 4 386177 6049 79352158
Tissue infiltration 17.34 9.65 19 386162 672 79357535
Peritonitis lupus 17.34 9.65 4 386177 0 79358207
Phagocytosis 17.34 9.65 4 386177 0 79358207
Cytomegalovirus myelomeningoradiculitis 17.34 9.65 4 386177 0 79358207
Tracheal ulcer 17.34 9.65 4 386177 0 79358207
Isosporiasis 17.32 9.65 11 386170 177 79358030
Metastatic malignant melanoma 17.32 9.65 41 386140 2822 79355385
Ocular vasculitis 17.31 9.65 6 386175 20 79358187
Alveolitis 17.30 9.65 52 386129 4128 79354079
Second primary malignancy 17.30 9.65 124 386057 14226 79343981
Diffuse large B-cell lymphoma stage II 17.29 9.65 9 386172 97 79358110
Relapsing fever 17.16 9.65 15 386166 400 79357807
Vasogenic cerebral oedema 17.14 9.65 28 386153 1465 79356742
Meningoencephalitis amoebic 17.14 9.65 10 386171 137 79358070
Infarction 17.12 9.65 55 386126 4527 79353680
Pulmonary haemorrhage 17.07 9.65 126 386055 14591 79343616
Osteomyelitis salmonella 17.07 9.65 7 386174 41 79358166
Gastrointestinal mucosa hyperaemia 17.05 9.65 16 386165 469 79357738
Pseudarthrosis 17.02 9.65 13 386168 285 79357922
Histiocytic sarcoma 17 9.65 8 386173 68 79358139
Non-Hodgkin's lymphoma 16.95 9.65 28 386153 1479 79356728
Anorectal infection bacterial 16.94 9.65 5 386176 8 79358199
Pancreatic pseudocyst haemorrhage 16.94 9.65 5 386176 8 79358199
Papule 16.94 9.65 76 386105 7331 79350876
Duodenitis 16.92 9.65 80 386101 7887 79350320
Necrotising scleritis 16.91 9.65 12 386169 234 79357973
Aphonia 16.90 9.65 15 386166 10297 79347910
Ganglioneuroma 16.89 9.65 10 386171 141 79358066
Upper-airway cough syndrome 16.88 9.65 19 386162 11674 79346533
Blood pressure decreased 16.88 9.65 360 385821 99106 79259101
Thrombosis in device 16.84 9.65 3 386178 5439 79352768
Orthostatic intolerance 16.80 9.65 32 386149 1892 79356315
Vaginal haemorrhage 16.79 9.65 52 386129 21765 79336442
Duodenal ulcer haemorrhage 16.76 9.65 74 386107 7089 79351118
Chronic graft versus host disease in intestine 16.74 9.65 14 386167 351 79357856
Respiratory tract infection 16.73 9.65 330 385851 48359 79309848
Rash vesicular 16.73 9.65 65 386116 5880 79352327
Lymphangiectasia 16.67 9.65 9 386172 105 79358102
Pre-eclampsia 16.67 9.65 73 386108 6968 79351239
Generalised oedema 16.67 9.65 182 385999 23527 79334680
Veillonella infection 16.66 9.65 7 386174 44 79358163
Cellulitis 16.63 9.65 666 385515 108394 79249813
Sphincter of Oddi dysfunction 16.61 9.65 15 386166 418 79357789
Salivary hypersecretion 16.60 9.65 27 386154 14197 79344010
Complications of transplanted heart 16.57 9.65 14 386167 356 79357851
Reticulin increased 16.57 9.65 5 386176 9 79358198
Pancreatitis necrotising 16.54 9.65 49 386132 3859 79354348
Pulmonary fibrosis 16.54 9.65 303 385878 43809 79314398
Speech disorder 16.54 9.65 176 386005 54269 79303938
Cystitis viral 16.53 9.65 19 386162 709 79357498
Soft tissue infection 16.51 9.65 49 386132 3863 79354344
Coagulation test abnormal 16.50 9.65 26 386155 1319 79356888
Acanthamoeba infection 16.50 9.65 16 386165 489 79357718
Helicobacter sepsis 16.47 9.65 6 386175 24 79358183
Hepatitis infectious mononucleosis 16.47 9.65 10 386171 148 79358059
Injection site induration 16.43 9.65 14 386167 9805 79348402
Gastrointestinal amyloidosis 16.42 9.65 8 386173 74 79358133
Cyst 16.41 9.65 26 386155 13814 79344393
Retinal infiltrates 16.40 9.65 7 386174 46 79358161
Herpes simplex encephalitis 16.36 9.65 19 386162 717 79357490
Enterocolitis bacterial 16.33 9.65 18 386163 641 79357566
Nail disorder 16.31 9.65 20 386161 11832 79346375
Neurosarcoidosis 16.31 9.65 14 386167 364 79357843
Body temperature increased 16.31 9.65 137 386044 44283 79313924
Mood swings 16.30 9.65 46 386135 19834 79338373
Product administration error 16.30 9.65 89 386092 31757 79326450
Factitious disorder 16.29 9.65 10 386171 151 79358056
Venoocclusive disease 16.28 9.65 54 386127 4519 79353688
Amoebic dysentery 16.28 9.65 6 386175 25 79358182
Food allergy 16.28 9.65 17 386164 10807 79347400
Encephalitis autoimmune 16.28 9.65 35 386146 2259 79355948
Picornavirus infection 16.23 9.65 5 386176 10 79358197
Frustration tolerance decreased 16.23 9.65 8 386173 7494 79350713
Neoplasm malignant 16.23 9.65 89 386092 31721 79326486
Polyarthritis 16.22 9.65 108 386073 12094 79346113
Cerebral fungal infection 16.20 9.65 15 386166 432 79357775
Hypomagnesaemia 16.20 9.65 147 386034 46764 79311443
Drug use disorder 16.19 9.65 11 386170 8640 79349567
Gastric stenosis 16.18 9.65 10 386171 153 79358054
Secretion discharge 16.18 9.65 30 386151 14992 79343215
Acanthoma 16.15 9.65 7 386174 48 79358159
West Nile viral infection 16.11 9.65 22 386159 980 79357227
Secondary immunodeficiency 16.09 9.65 43 386138 3191 79355016
Atrioventricular block 16.06 9.65 27 386154 14014 79344193
Abscess bacterial 16.04 9.65 20 386161 814 79357393
Bladder transitional cell carcinoma stage III 16.03 9.65 7 386174 49 79358158
Quadrantanopia 16.02 9.65 11 386170 203 79358004
Insurance issue 16.01 9.65 4 386177 5729 79352478
Abscess limb 15.99 9.65 72 386109 6955 79351252
Pneumonia staphylococcal 15.99 9.65 56 386125 4818 79353389
Intentional product use issue 15.92 9.65 589 385592 151523 79206684
Brain stem infarction 15.92 9.65 32 386149 1969 79356238
Lymphangioma 15.91 9.65 6 386175 27 79358180
Substance-induced mood disorder 15.90 9.65 9 386172 116 79358091
Toothache 15.80 9.65 47 386134 19923 79338284
Central nervous system immune reconstitution inflammatory response 15.79 9.65 7 386174 51 79358156
Device breakage 15.79 9.65 17 386164 10658 79347549
Pain in jaw 15.77 9.65 145 386036 46006 79312201
Scopulariopsis infection 15.77 9.65 9 386172 118 79358089
Liver transplant failure 15.77 9.65 9 386172 118 79358089
Removal of renal transplant 15.74 9.65 6 386175 28 79358179
Herpangina 15.74 9.65 6 386175 28 79358179
Respiratory gas exchange disorder 15.71 9.65 20 386161 831 79357376
Herpes oesophagitis 15.66 9.65 14 386167 385 79357822
Injection site discomfort 15.66 9.65 3 386178 5163 79353044
Gastric ulcer perforation 15.64 9.65 33 386148 2102 79356105
Serositis 15.58 9.65 20 386161 838 79357369
Myocardiac abscess 15.57 9.65 6 386175 29 79358178
Pneumaturia 15.57 9.65 6 386175 29 79358178
Tooth dislocation 15.57 9.65 6 386175 29 79358178
Urinary incontinence 15.55 9.65 125 386056 40784 79317423
Aspergillus test positive 15.51 9.65 19 386162 759 79357448
Sequestrectomy 15.51 9.65 20 386161 842 79357365
Coronary artery bypass 15.51 9.65 5 386176 6057 79352150
Serum ferritin increased 15.49 9.65 91 386090 9756 79348451
Cutaneous vasculitis 15.49 9.65 80 386101 8172 79350035
JC virus CSF test positive 15.48 9.65 10 386171 166 79358041
Bowen's disease 15.44 9.65 9 386172 123 79358084
Coronary arterial stent insertion 15.44 9.65 5 386176 6039 79352168
Autoimmune colitis 15.43 9.65 28 386153 1595 79356612
Haemodialysis 15.43 9.65 145 386036 18023 79340184
Parkinsonism 15.43 9.65 36 386145 16548 79341659
Hyperuricaemia 15.43 9.65 104 386077 11695 79346512
Disseminated cytomegaloviral infection 15.43 9.65 15 386166 460 79357747
Rectosigmoid cancer 15.41 9.65 12 386169 271 79357936
Large intestine erosion 15.41 9.65 6 386175 30 79358177
Rectal cancer metastatic 15.40 9.65 15 386166 461 79357746
Type 2 lepra reaction 15.39 9.65 11 386170 217 79357990
Intestinal pseudo-obstruction 15.39 9.65 37 386144 2572 79355635
Lymphadenitis bacterial 15.39 9.65 8 386173 86 79358121
Septic embolus 15.37 9.65 32 386149 2019 79356188
Pyomyositis 15.36 9.65 17 386164 608 79357599
Non-alcoholic steatohepatitis 15.36 9.65 34 386147 2238 79355969
Thinking abnormal 15.34 9.65 25 386156 13136 79345071
Genitourinary tract infection 15.33 9.65 12 386169 273 79357934
Gingivitis ulcerative 15.33 9.65 12 386169 273 79357934
Cholelithiasis 15.29 9.65 172 386009 52492 79305715
Sinus headache 15.29 9.65 3 386178 5077 79353130
Corneal oedema 15.29 9.65 37 386144 2583 79355624
Angina unstable 15.28 9.65 36 386145 16491 79341716
Coronary artery occlusion 15.27 9.65 32 386149 15283 79342924
Euglycaemic diabetic ketoacidosis 15.26 9.65 7 386174 6837 79351370
CSF protein increased 15.26 9.65 24 386157 1216 79356991
Emotional disorder 15.26 9.65 29 386152 14358 79343849
Atrioventricular block first degree 15.25 9.65 23 386158 12468 79345739
Transplant abscess 15.25 9.65 6 386175 31 79358176
Microscopic polyangiitis 15.24 9.65 14 386167 399 79357808
Small intestinal obstruction 15.21 9.65 74 386107 27198 79331009
Encephalomyelitis 15.18 9.65 11 386170 222 79357985
Cerebral venous sinus thrombosis 15.17 9.65 34 386147 2257 79355950
Corneal disorder 15.17 9.65 34 386147 2257 79355950
Emphysematous pyelonephritis 15.15 9.65 13 386168 338 79357869
Concomitant disease progression 15.13 9.65 44 386137 3429 79354778
Live birth 15.13 9.65 148 386033 18596 79339611
Vasculitic rash 15.13 9.65 33 386148 2151 79356056
Hookworm infection 15.12 9.65 4 386177 3 79358204
Paraneoplastic arthritis 15.12 9.65 4 386177 3 79358204
Hyposplenism 15.12 9.65 4 386177 3 79358204
Pyelonephritis chronic 15.11 9.65 12 386169 279 79357928
Haptoglobin decreased 15.11 9.65 25 386156 1322 79356885
Campylobacter infection 15.07 9.65 30 386151 1833 79356374
Exposure via body fluid 15.05 9.65 13 386168 341 79357866
Portal vein thrombosis 15.02 9.65 62 386119 5765 79352442
Cardiac operation 15 9.65 3 386178 5009 79353198
Road traffic accident 15.00 9.65 137 386044 43527 79314680
Precursor T-lymphoblastic lymphoma/leukaemia 15.00 9.65 8 386173 91 79358116
Inappropriate antidiuretic hormone secretion 14.97 9.65 194 385987 26119 79332088
Hepatic infection fungal 14.97 9.65 11 386170 227 79357980
Colitis ulcerative 14.96 9.65 244 385937 34498 79323709
Squamous cell carcinoma of lung 14.94 9.65 34 386147 2280 79355927
Dermatomyositis 14.93 9.65 45 386136 3578 79354629
Endothelial dysfunction 14.93 9.65 11 386170 228 79357979
Cutaneous T-cell lymphoma recurrent 14.93 9.65 7 386174 59 79358148
Sickle cell anaemia with crisis 14.92 9.65 10 386171 7912 79350295
Gestational hypertension 14.89 9.65 30 386151 1849 79356358
Paresis 14.89 9.65 50 386131 4211 79353996
Bone abscess 14.88 9.65 15 386166 481 79357726
Neutrophilia 14.87 9.65 77 386104 7874 79350333
Temperature intolerance 14.87 9.65 15 386166 9690 79348517
Gastrointestinal erosion 14.87 9.65 22 386159 1056 79357151
Cryptitis 14.86 9.65 12 386169 286 79357921
Mood altered 14.86 9.65 41 386140 17806 79340401
Vanishing bile duct syndrome 14.83 9.65 29 386152 1749 79356458
Sebaceous gland disorder 14.83 9.65 7 386174 60 79358147
Rectal cancer 14.82 9.65 44 386137 3469 79354738
Breast pain 14.82 9.65 11 386170 8254 79349953
Subclavian artery embolism 14.82 9.65 5 386176 15 79358192
Bacteriuria 14.81 9.65 24 386157 1247 79356960
Vulval ulceration 14.80 9.65 11 386170 231 79357976
Oesophageal ulcer 14.79 9.65 70 386111 6905 79351302
Ovarian cyst 14.79 9.65 24 386157 12631 79345576
Infected lymphocele 14.72 9.65 11 386170 233 79357974
Drug-induced liver injury 14.72 9.65 422 385759 65695 79292512
Gastroenteritis Escherichia coli 14.71 9.65 17 386164 638 79357569
Neutrophil morphology abnormal 14.70 9.65 8 386173 95 79358112
Pneumonia mycoplasmal 14.70 9.65 26 386155 1452 79356755
Brain oedema 14.69 9.65 187 385994 25076 79333131
Reticulocytopenia 14.68 9.65 11 386170 234 79357973
Gouty tophus 14.68 9.65 14 386167 419 79357788
Temperature regulation disorder 14.67 9.65 5 386176 5848 79352359
Hypertrichosis 14.66 9.65 24 386157 1258 79356949
Suspected transmission of an infectious agent via product 14.66 9.65 23 386158 1163 79357044
Chorioretinal folds 14.65 9.65 6 386175 35 79358172
Hysterectomy 14.64 9.65 6 386175 6266 79351941
Jejunal stenosis 14.63 9.65 8 386173 96 79358111
Nodal marginal zone B-cell lymphoma 14.59 9.65 4 386177 4 79358203
Dysplasia 14.59 9.65 25 386156 1361 79356846
Infection protozoal 14.58 9.65 5 386176 16 79358191
Pregnancy on contraceptive 14.57 9.65 20 386161 895 79357312
Metastatic carcinoma of the bladder 14.56 9.65 11 386170 237 79357970
Ureteral necrosis 14.56 9.65 8 386173 97 79358110
Metastasis 14.55 9.65 69 386112 6811 79351396
Terminal ileitis 14.54 9.65 20 386161 897 79357310
Cardiac autonomic neuropathy 14.53 9.65 7 386174 63 79358144
Cutaneous T-cell lymphoma stage IV 14.51 9.65 6 386175 36 79358171
Bronchiolitis 14.51 9.65 49 386132 4139 79354068
Eye infection 14.51 9.65 22 386159 11898 79346309
Folliculitis 14.50 9.65 185 385996 55195 79303012
Adenomatous polyposis coli 14.49 9.65 11 386170 239 79357968
Liver function test abnormal 14.48 9.65 412 385769 64063 79294144
Paranoia 14.48 9.65 47 386134 19385 79338822
C-reactive protein 14.47 9.65 55 386126 4924 79353283
Angiosarcoma metastatic 14.43 9.65 9 386172 140 79358067
Dystonia 14.43 9.65 54 386127 21345 79336862
Gastroenteritis clostridial 14.35 9.65 20 386161 908 79357299
Intestinal ulcer 14.35 9.65 31 386150 2007 79356200
Pneumocystis test positive 14.35 9.65 5 386176 17 79358190
Pleural infection bacterial 14.35 9.65 5 386176 17 79358190
Bedridden 14.34 9.65 104 386077 11975 79346232
Feeling cold 14.32 9.65 81 386100 28648 79329559
Coronavirus infection 14.30 9.65 73 386108 7424 79350783
Arthropod bite 14.27 9.65 12 386169 8459 79349748
Flatulence 14.27 9.65 135 386046 42589 79315618
Hepatitis toxic 14.26 9.65 56 386125 5091 79353116
Medication error 14.25 9.65 240 385941 68402 79289805
Enteritis 14.24 9.65 120 386061 14463 79343744
Alcohol use 14.23 9.65 3 386178 4828 79353379
Weight bearing difficulty 14.22 9.65 41 386140 3180 79355027
Cerebral haemorrhage 14.22 9.65 373 385808 57300 79300907
Autoimmune thyroiditis 14.20 9.65 49 386132 4184 79354023
Purulence 14.19 9.65 32 386149 2133 79356074
Catheterisation cardiac 14.17 9.65 5 386176 5723 79352484
Optic discs blurred 14.16 9.65 7 386174 67 79358140
Myelitis transverse 14.15 9.65 30 386151 1917 79356290
Cryptococcus test positive 14.13 9.65 5 386176 18 79358189
Enterovirus myocarditis 14.12 9.65 4 386177 5 79358202
Status asthmaticus 14.11 9.65 21 386160 1013 79357194
Cholangitis sclerosing 14.08 9.65 36 386145 2601 79355606
Coinfection 14.07 9.65 7 386174 68 79358139
Upper respiratory tract infection 14.04 9.65 335 385846 90833 79267374
Porokeratosis 14.03 9.65 11 386170 251 79357956
Facial paralysis 14.01 9.65 160 386021 20912 79337295
Alpha tumour necrosis factor increased 13.98 9.65 6 386175 40 79358167
Viral cardiomyopathy 13.98 9.65 6 386175 40 79358167
Pneumonia aspiration 13.97 9.65 424 385757 66543 79291664
Aphthous ulcer 13.95 9.65 134 386047 16755 79341452
Burkitt's lymphoma stage III 13.93 9.65 5 386176 19 79358188
Cardiovascular disorder 13.91 9.65 141 386040 17884 79340323
Metastatic bronchial carcinoma 13.88 9.65 11 386170 255 79357952
Neutropenic infection 13.87 9.65 34 386147 2393 79355814
Hemianopia homonymous 13.87 9.65 24 386157 1317 79356890
Ulna fracture 13.87 9.65 22 386159 1123 79357084
Transient hypogammaglobulinaemia of infancy 13.86 9.65 6 386175 41 79358166
N-telopeptide urine increased 13.86 9.65 6 386175 41 79358166
Lactobacillus infection 13.85 9.65 13 386168 381 79357826
Acute monocytic leukaemia 13.84 9.65 15 386166 524 79357683
Heart rate abnormal 13.81 9.65 6 386175 6051 79352156
Bradypnoea 13.79 9.65 6 386175 6046 79352161
Vein disorder 13.75 9.65 4 386177 5178 79353029
Pollakiuria 13.74 9.65 115 386066 37202 79321005
Myocardial calcification 13.74 9.65 6 386175 42 79358165
Intestinal villi atrophy 13.73 9.65 14 386167 455 79357752
Pancreatic leak 13.73 9.65 5 386176 20 79358187
Muscle tightness 13.72 9.65 26 386155 12888 79345319
Hypoproteinaemia 13.72 9.65 47 386134 3999 79354208
Acute lymphocytic leukaemia 13.71 9.65 54 386127 4915 79353292
Oligohydramnios 13.71 9.65 42 386139 3370 79354837
Bullous impetigo 13.70 9.65 4 386177 6 79358201
Threatened labour 13.69 9.65 16 386165 608 79357599
Serum sickness 13.69 9.65 44 386137 3622 79354585
Hypoaesthesia oral 13.68 9.65 30 386151 14094 79344113
Trichodysplasia spinulosa 13.67 9.65 18 386163 774 79357433
Tendon pain 13.65 9.65 59 386122 5599 79352608
Meningitis enteroviral 13.65 9.65 7 386174 73 79358134
Hypereosinophilic syndrome 13.64 9.65 15 386166 533 79357674
Respiratory rate increased 13.62 9.65 56 386125 21544 79336663
Pelvic venous thrombosis 13.61 9.65 32 386149 2193 79356014
Lipohypertrophy 13.60 9.65 19 386162 865 79357342
Venous thrombosis limb 13.59 9.65 50 386131 4407 79353800
Onychoclasis 13.58 9.65 5 386176 5573 79352634
Liver function test increased 13.57 9.65 125 386056 39648 79318559
Cranial nerve palsies multiple 13.56 9.65 8 386173 112 79358095
Extrapulmonary tuberculosis 13.55 9.65 13 386168 392 79357815
Abscess rupture 13.54 9.65 12 386169 326 79357881
Osteitis 13.54 9.65 46 386135 3897 79354310
Gastric pneumatosis 13.53 9.65 5 386176 21 79358186
Vagus nerve paralysis 13.53 9.65 5 386176 21 79358186
Meningism 13.53 9.65 17 386164 697 79357510
Pre-existing condition improved 13.52 9.65 5 386176 5558 79352649
Anal incontinence 13.50 9.65 44 386137 18124 79340083
Mucocutaneous leishmaniasis 13.46 9.65 14 386167 466 79357741
Application site erythema 13.46 9.65 4 386177 5106 79353101
Rhodococcus infection 13.42 9.65 12 386169 330 79357877
Blood sodium decreased 13.40 9.65 100 386081 33155 79325052
Anorectal varices 13.39 9.65 6 386175 45 79358162
Transitional cell carcinoma metastatic 13.39 9.65 6 386175 45 79358162
Osteopenia 13.39 9.65 142 386039 18222 79339985
Urethral obstruction 13.38 9.65 11 386170 269 79357938
Mediastinal abscess 13.38 9.65 8 386173 115 79358092
Troponin increased 13.38 9.65 48 386133 19207 79339000
Tachypnoea 13.37 9.65 224 385957 31839 79326368
Pustule 13.35 9.65 30 386151 1995 79356212
Gingival cancer 13.35 9.65 5 386176 22 79358185
Hirsutism 13.34 9.65 24 386157 1358 79356849
Cholecystitis chronic 13.34 9.65 17 386164 9889 79348318
Fear of injection 13.33 9.65 10 386171 7464 79350743
Encephalitis post varicella 13.33 9.65 4 386177 7 79358200
Epiphyses delayed fusion 13.33 9.65 4 386177 7 79358200
Abortion missed 13.32 9.65 23 386158 1260 79356947
Airway peak pressure increased 13.30 9.65 12 386169 334 79357873
Vaginal discharge 13.29 9.65 10 386171 7453 79350754
Non-cirrhotic portal hypertension 13.29 9.65 14 386167 473 79357734
Spleen atrophy 13.28 9.65 6 386175 46 79358161
Haematotoxicity 13.25 9.65 124 386057 15395 79342812
Schizophrenia 13.21 9.65 35 386146 15405 79342802
Epididymitis 13.18 9.65 29 386152 1901 79356306
Anal abscess 13.17 9.65 84 386097 9271 79348936
Haematocolpos 13.17 9.65 6 386175 47 79358160
Quadriplegia 13.16 9.65 41 386140 3319 79354888
Blood pressure abnormal 13.16 9.65 41 386140 17128 79341079
Menstruation irregular 13.16 9.65 4 386177 5032 79353175
Tuberculosis of central nervous system 13.15 9.65 14 386167 479 79357728
Necrotising herpetic retinopathy 13.14 9.65 8 386173 119 79358088
Haemophilus infection 13.13 9.65 32 386149 2244 79355963
Bone marrow necrosis 13.11 9.65 11 386170 277 79357930
Chronic hepatitis C 13.10 9.65 16 386165 637 79357570
Abscess drainage 13.08 9.65 16 386165 638 79357569
Peroneal nerve palsy 13.08 9.65 61 386120 5981 79352226
Hyperferritinaemia 13.07 9.65 17 386164 722 79357485
Locked-in syndrome 13.07 9.65 17 386164 722 79357485
Device failure 13.06 9.65 7 386174 6254 79351953
Blepharospasm 13.02 9.65 6 386175 5845 79352362
Haemorrhoids 13.01 9.65 85 386096 29043 79329164
Blood beta-D-glucan abnormal 13.01 9.65 3 386178 0 79358207
Chronic active Epstein-Barr virus infection 13.01 9.65 3 386178 0 79358207
Malignant glaucoma 13.01 9.65 3 386178 0 79358207
Malignant urinary tract neoplasm 13.01 9.65 3 386178 0 79358207
Bezold abscess 13.01 9.65 3 386178 0 79358207
Splint application 13.01 9.65 3 386178 0 79358207
Tuberculous tenosynovitis 13.01 9.65 3 386178 0 79358207
Restrictive allograft syndrome 13.00 9.65 5 386176 24 79358183
Appetite disorder 12.99 9.65 11 386170 7728 79350479
Fasciitis 12.99 9.65 18 386163 813 79357394
Gardner-Diamond syndrome 12.99 9.65 4 386177 8 79358199
Movement disorder 12.97 9.65 78 386103 27181 79331026
Femur fracture 12.96 9.65 261 385920 38391 79319816
Cryoglobulinaemia 12.96 9.65 18 386163 815 79357392
Type 3 diabetes mellitus 12.96 9.65 6 386175 49 79358158
Hypozincaemia 12.96 9.65 6 386175 49 79358158
VIth nerve paralysis 12.95 9.65 26 386155 1598 79356609
Peptostreptococcus infection 12.94 9.65 7 386174 82 79358125
Retinal scar 12.94 9.65 13 386168 415 79357792
Hepatitis B surface antigen positive 12.93 9.65 9 386172 170 79358037
Cerebral cyst 12.92 9.65 13 386168 416 79357791
Subdural haematoma 12.92 9.65 94 386087 31340 79326867
Spindle cell sarcoma 12.91 9.65 10 386171 224 79357983
Extra dose administered 12.90 9.65 13 386168 8402 79349805
Graft complication 12.89 9.65 17 386164 732 79357475
Intestinal intraepithelial lymphocytes increased 12.88 9.65 9 386172 171 79358036
Facial paresis 12.86 9.65 57 386124 5469 79352738
Haemorrhagic stroke 12.86 9.65 21 386160 11025 79347182
Weight fluctuation 12.85 9.65 23 386158 11652 79346555
Splenic neoplasm malignancy unspecified 12.85 9.65 6 386175 50 79358157
Chronic graft versus host disease in liver 12.83 9.65 16 386165 651 79357556
Dyspnoea 12.83 9.65 3830 382351 853195 78505012
Dermatitis contact 12.82 9.65 21 386160 11012 79347195
Reticulocytosis 12.78 9.65 14 386167 495 79357712
Autoimmune pancreatitis 12.77 9.65 16 386165 654 79357553
Blood pressure inadequately controlled 12.75 9.65 7 386174 6170 79352037
Disorder of orbit 12.74 9.65 8 386173 126 79358081
Alcohol abuse 12.73 9.65 5 386176 5358 79352849
Scratch 12.73 9.65 13 386168 8350 79349857
Lower limb fracture 12.73 9.65 170 386011 23045 79335162
Pyelonephritis fungal 12.72 9.65 10 386171 229 79357978
Ear pain 12.70 9.65 100 386081 32769 79325438
Capnocytophaga infection 12.69 9.65 8 386173 127 79358080
Abdominal wall haematoma 12.68 9.65 52 386129 4821 79353386
Corectopia 12.67 9.65 4 386177 9 79358198
Leukoerythroblastic anaemia 12.67 9.65 4 386177 9 79358198
Conjunctival deposit 12.67 9.65 4 386177 9 79358198
Macular degeneration 12.67 9.65 22 386159 11274 79346933
Paranasal sinus discomfort 12.66 9.65 3 386178 4453 79353754
Post-acute COVID-19 syndrome 12.65 9.65 14 386167 501 79357706
Rash pustular 12.64 9.65 96 386085 11215 79346992
Cerebral salt-wasting syndrome 12.64 9.65 8 386173 128 79358079
Gallbladder necrosis 12.64 9.65 8 386173 128 79358079
Chorioretinitis 12.62 9.65 20 386161 1020 79357187
Idiopathic interstitial pneumonia 12.61 9.65 10 386171 232 79357975
Blood loss anaemia 12.61 9.65 36 386145 15462 79342745
Putamen haemorrhage 12.60 9.65 14 386167 503 79357704
Hypopnoea 12.60 9.65 5 386176 5324 79352883
Gastritis 12.60 9.65 313 385868 47680 79310527
Gastrointestinal mucormycosis 12.59 9.65 13 386168 429 79357778
Neutrophil count decreased 12.57 9.65 566 385615 93393 79264814
Eye pruritus 12.55 9.65 54 386127 20516 79337691
Calculus urinary 12.54 9.65 33 386148 2427 79355780
Juvenile idiopathic arthritis 12.53 9.65 51 386130 4712 79353495
Subarachnoid haemorrhage 12.53 9.65 177 386004 24288 79333919
Post-traumatic stress disorder 12.53 9.65 4 386177 4877 79353330
Malignant respiratory tract neoplasm 12.53 9.65 5 386176 27 79358180
Hypopharyngeal cancer 12.52 9.65 7 386174 88 79358119
Biliary tract disorder 12.52 9.65 26 386155 1638 79356569
Peripheral circulatory failure 12.50 9.65 21 386160 1125 79357082
Aneurysm ruptured 12.49 9.65 19 386162 935 79357272
Mucosal haemorrhage 12.48 9.65 34 386147 2552 79355655
Dystrophic calcification 12.48 9.65 8 386173 131 79358076
Typhoid fever 12.46 9.65 6 386175 54 79358153
Basal ganglion degeneration 12.45 9.65 13 386168 435 79357772
Lymphocyte morphology abnormal 12.43 9.65 19 386162 939 79357268
Urethritis 12.41 9.65 15 386166 591 79357616
T-cell type acute leukaemia 12.40 9.65 9 386172 182 79358025
Spinal operation 12.40 9.65 12 386169 7905 79350302
Therapeutic response unexpected 12.39 9.65 52 386129 19894 79338313
Parvimonas micra infection 12.38 9.65 5 386176 28 79358179
B-lymphocyte abnormalities 12.38 9.65 5 386176 28 79358179
Breath sounds abnormal 12.37 9.65 38 386143 15946 79342261
Muscle atrophy 12.37 9.65 95 386086 11137 79347070
Autoimmune disorder 12.37 9.65 129 386052 16483 79341724
Febrile infection 12.35 9.65 40 386141 3306 79354901
Oesophageal carcinoma 12.35 9.65 94 386087 10990 79347217
Feeding disorder 12.33 9.65 39 386142 16215 79341992
Acute disseminated encephalomyelitis 12.32 9.65 11 386170 302 79357905
Hemianopia heteronymous 12.31 9.65 7 386174 91 79358116
Acute febrile neutrophilic dermatosis 12.28 9.65 44 386137 3828 79354379
Lower gastrointestinal perforation 12.27 9.65 6 386175 56 79358151
Urine abnormality 12.26 9.65 13 386168 8206 79350001
Pancreatic duct stenosis 12.26 9.65 10 386171 242 79357965
Tibia fracture 12.25 9.65 55 386126 5306 79352901
Palmar-plantar erythrodysaesthesia syndrome 12.25 9.65 102 386079 33032 79325175
Arthritis reactive 12.25 9.65 15 386166 599 79357608
Muscle twitching 12.24 9.65 70 386111 24694 79333513
Retinal degeneration 12.24 9.65 22 386159 1244 79356963
Thyroid stimulating hormone deficiency 12.23 9.65 5 386176 29 79358178
Duodenal stenosis 12.23 9.65 17 386164 770 79357437
Aspergillus test 12.23 9.65 5 386176 29 79358178
Disorientation 12.23 9.65 222 385959 62554 79295653
Gastrointestinal oedema 12.22 9.65 34 386147 2584 79355623
Achromobacter infection 12.22 9.65 8 386173 136 79358071
Infective thrombosis 12.18 9.65 7 386174 93 79358114
Beta-N-acetyl-D-glucosaminidase increased 12.18 9.65 6 386175 57 79358150
Oedema due to cardiac disease 12.18 9.65 6 386175 57 79358150
Peritonitis viral 12.18 9.65 6 386175 57 79358150
Product dispensing error 12.17 9.65 29 386152 13234 79344973
Beta 2 microglobulin urine increased 12.17 9.65 8 386173 137 79358070
Oral administration complication 12.17 9.65 8 386173 137 79358070
Non-cardiac chest pain 12.16 9.65 17 386164 9507 79348700
Liver transplant 12.15 9.65 48 386133 4375 79353832
Meningitis fungal 12.11 9.65 9 386172 189 79358018
Oesophageal tuberculosis 12.11 9.65 4 386177 11 79358196
Anterior chamber pigmentation 12.11 9.65 4 386177 11 79358196
Abnormal dreams 12.10 9.65 23 386158 11389 79346818
Papilloedema 12.10 9.65 61 386120 6172 79352035
Acute on chronic liver failure 12.08 9.65 11 386170 310 79357897
Retinitis viral 12.07 9.65 8 386173 139 79358068
Hemiparesis 12.05 9.65 230 385951 33503 79324704
Optic atrophy 12.04 9.65 28 386153 1905 79356302
Rheumatoid factor increased 12.03 9.65 27 386154 1794 79356413
Otitis media 12.03 9.65 60 386121 6046 79352161
Lip swelling 12.02 9.65 271 385910 40640 79317567
Duodenal ulcer perforation 12.01 9.65 237 385944 65974 79292233
Ileus 12.01 9.65 186 385995 26025 79332182
Metabolic encephalopathy 12.00 9.65 16 386165 9131 79349076
Cryptococcal meningoencephalitis 11.98 9.65 10 386171 250 79357957
Leukaemia recurrent 11.95 9.65 35 386146 2739 79355468
Blood potassium decreased 11.95 9.65 156 386025 46356 79311851
Protein-losing gastroenteropathy 11.94 9.65 15 386166 615 79357592
Antipsychotic drug level increased 11.94 9.65 7 386174 5950 79352257
Ventricular fibrillation 11.93 9.65 98 386083 31828 79326379
Long QT syndrome 11.93 9.65 7 386174 5948 79352259
HELLP syndrome 11.92 9.65 17 386164 789 79357418
Sweat gland disorder 11.91 9.65 9 386172 194 79358013
Breast cancer stage I 11.91 9.65 9 386172 6691 79351516
Troponin I increased 11.89 9.65 50 386131 4688 79353519
Infection 11.89 9.65 1341 384840 240371 79117836
Pneumonitis chemical 11.88 9.65 13 386168 459 79357748
Corneal epithelium defect 11.88 9.65 16 386165 703 79357504
Infective exacerbation of chronic obstructive airways disease 11.87 9.65 35 386146 2749 79355458
Mesenteric vascular insufficiency 11.87 9.65 8 386173 143 79358064
Diffuse large B-cell lymphoma stage III 11.86 9.65 7 386174 98 79358109
Paraneoplastic thrombosis 11.85 9.65 4 386177 12 79358195
Argentine haemorrhagic fever 11.85 9.65 4 386177 12 79358195
Cystitis escherichia 11.85 9.65 15 386166 620 79357587
Drug effective for unapproved indication 11.84 9.65 59 386122 5942 79352265
Sputum retention 11.83 9.65 20 386161 1077 79357130
Spleen tuberculosis 11.82 9.65 5 386176 32 79358175
Tumour invasion 11.82 9.65 12 386169 388 79357819
Blood lactate dehydrogenase decreased 11.82 9.65 11 386170 319 79357888
Ocular lymphoma 11.80 9.65 7 386174 99 79358108
Skin tightness 11.78 9.65 6 386175 5516 79352691
Abnormal behaviour 11.77 9.65 116 386065 36305 79321902
Ocular hyperaemia 11.76 9.65 84 386097 28122 79330085
Scleritis 11.75 9.65 47 386134 4309 79353898
Actinomycotic sepsis 11.74 9.65 7 386174 100 79358107
Cardiogenic shock 11.74 9.65 138 386043 41776 79316431
Histology abnormal 11.73 9.65 11 386170 322 79357885
Chronic graft versus host disease in eye 11.73 9.65 8 386173 146 79358061
Coronary artery aneurysm 11.73 9.65 8 386173 146 79358061
Pericarditis constrictive 11.72 9.65 15 386166 627 79357580
Myoclonus 11.71 9.65 82 386099 27578 79330629
Hypovolaemia 11.70 9.65 45 386136 17646 79340561
Pelvic pain 11.70 9.65 30 386151 13351 79344856
Bradykinesia 11.69 9.65 13 386168 8030 79350177
Skin fissures 11.67 9.65 29 386152 13044 79345163
Thrombocytosis 11.66 9.65 76 386105 8450 79349757
Mucocutaneous ulceration 11.65 9.65 12 386169 395 79357812
Ruptured cerebral aneurysm 11.63 9.65 14 386167 549 79357658
Papillitis 11.62 9.65 7 386174 102 79358105
Macrophage activation 11.62 9.65 4 386177 13 79358194
Bronchopulmonary disease 11.62 9.65 4 386177 13 79358194
Acute myocardial infarction 11.61 9.65 284 385897 76752 79281455
Mechanical ileus 11.60 9.65 18 386163 901 79357306
Nasal polyps 11.60 9.65 11 386170 7316 79350891
Tooth fracture 11.57 9.65 24 386157 11506 79346701
Amniotic fluid volume increased 11.54 9.65 8 386173 150 79358057
Portal venous gas 11.53 9.65 12 386169 400 79357807
Inadequate analgesia 11.52 9.65 4 386177 4625 79353582
Vascular hyalinosis 11.50 9.65 7 386174 104 79358103
Neuromyotonia 11.50 9.65 7 386174 104 79358103
Peritonsillar abscess 11.50 9.65 18 386163 908 79357299
Philadelphia positive acute lymphocytic leukaemia 11.50 9.65 6 386175 65 79358142
Iris transillumination defect 11.50 9.65 8 386173 151 79358056
Metastases to meninges 11.49 9.65 41 386140 3560 79354647
Leiomyoma 11.48 9.65 11 386170 331 79357876
Sluggishness 11.46 9.65 9 386172 6563 79351644
Toxic cardiomyopathy 11.43 9.65 12 386169 404 79357803
Pyuria 11.43 9.65 31 386150 2321 79355886
Idiopathic intracranial hypertension 11.43 9.65 38 386143 3184 79355023
Marasmus 11.43 9.65 19 386162 1009 79357198
Treatment noncompliance 11.43 9.65 181 386000 52087 79306120
Brown-Sequard syndrome 11.42 9.65 6 386175 66 79358141
Hepatic vein stenosis 11.42 9.65 6 386175 66 79358141
Proteus infection 11.40 9.65 29 386152 2089 79356118
Drug reaction with eosinophilia and systemic symptoms 11.40 9.65 399 385782 63845 79294362
Breast cancer female 11.38 9.65 24 386157 11437 79346770
Human herpes virus 6 serology positive 11.38 9.65 9 386172 208 79357999
Aortic aneurysm 11.38 9.65 75 386106 8371 79349836
Gas gangrene 11.37 9.65 10 386171 269 79357938
Arteriosclerosis coronary artery 11.35 9.65 46 386135 17770 79340437
Mycobacterial peritonitis 11.34 9.65 6 386175 67 79358140
Mitochondrial myopathy acquired 11.33 9.65 5 386176 36 79358171
Renal artery thrombosis 11.29 9.65 13 386168 486 79357721
Incorrect dose administered by device 11.28 9.65 5 386176 4984 79353223
Gait inability 11.27 9.65 209 385972 58708 79299499
Encephalitis Japanese B 11.27 9.65 6 386175 68 79358139
SARS-CoV-2 test positive 11.25 9.65 25 386156 11691 79346516
Attention-seeking behaviour 11.22 9.65 7 386174 109 79358098
Endocarditis candida 11.22 9.65 7 386174 109 79358098
Lacrimal gland enlargement 11.21 9.65 5 386176 37 79358170
Visual impairment 11.21 9.65 350 385831 91781 79266426
Acute biphenotypic leukaemia 11.19 9.65 8 386173 158 79358049
Diffuse large B-cell lymphoma stage I 11.18 9.65 4 386177 15 79358192
Shrinking lung syndrome 11.18 9.65 4 386177 15 79358192
Oesophageal squamous cell carcinoma stage IV 11.18 9.65 4 386177 15 79358192
Fine motor skill dysfunction 11.16 9.65 6 386175 5351 79352856
Paraesthesia oral 11.15 9.65 56 386125 20415 79337792
Alanine aminotransferase abnormal 11.15 9.65 16 386165 8851 79349356
Oesophageal squamous cell carcinoma 11.14 9.65 13 386168 493 79357714
Tinea versicolour 11.14 9.65 11 386170 344 79357863
Antimitochondrial antibody positive 11.11 9.65 7 386174 111 79358096
Nodular regenerative hyperplasia 11.11 9.65 22 386159 1339 79356868
Bladder disorder 11.07 9.65 17 386164 9148 79349059
Eating disorder 11.06 9.65 57 386124 20640 79337567
Laparotomy 11.03 9.65 12 386169 421 79357786
Lung opacity 11.02 9.65 52 386129 5122 79353085
Drug therapeutic incompatibility 11.02 9.65 8 386173 162 79358045
Drug interaction 11.00 9.65 2224 383957 412959 78945248
Mental impairment 11.00 9.65 51 386130 18985 79339222
Blood calcium increased 11.00 9.65 21 386160 10379 79347828
Pseudohypoaldosteronism 10.99 9.65 5 386176 39 79358168
Xanthelasma 10.97 9.65 8 386173 163 79358044
Nerve conduction studies abnormal 10.97 9.65 8 386173 163 79358044
Interleukin level increased 10.96 9.65 14 386167 584 79357623
Aortic rupture 10.95 9.65 9 386172 220 79357987
Eosinophilic otitis media 10.94 9.65 3 386178 3 79358204
Urine chloride increased 10.94 9.65 3 386178 3 79358204
Germ cell cancer metastatic 10.94 9.65 3 386178 3 79358204
Leukaemic infiltration hepatic 10.94 9.65 3 386178 3 79358204
Pearly penile papules 10.94 9.65 3 386178 3 79358204
White blood cell morphology abnormal 10.94 9.65 3 386178 3 79358204
Escherichia peritonitis 10.94 9.65 3 386178 3 79358204
Thought broadcasting 10.94 9.65 3 386178 3 79358204
Endocrine pancreatic disorder 10.94 9.65 3 386178 3 79358204
Precursor T-lymphoblastic lymphoma/leukaemia stage I 10.94 9.65 3 386178 3 79358204
Brachyspira infection 10.94 9.65 3 386178 3 79358204
Mean platelet volume 10.94 9.65 3 386178 3 79358204
Chorioretinal disorder 10.93 9.65 8 386173 164 79358043
Chest wall abscess 10.92 9.65 9 386172 221 79357986
Blister 10.91 9.65 470 385711 119006 79239201
Pulmonary fistula 10.90 9.65 6 386175 73 79358134
Angiodermatitis 10.90 9.65 6 386175 73 79358134
Pneumonia chlamydial 10.90 9.65 7 386174 115 79358092
Inflammatory myofibroblastic tumour 10.89 9.65 8 386173 165 79358042
Vascular pseudoaneurysm ruptured 10.89 9.65 8 386173 165 79358042
Pulmonary embolism 10.85 9.65 969 385212 170685 79187522
Polyp 10.83 9.65 14 386167 8093 79350114
Zika virus infection 10.79 9.65 4 386177 17 79358190
Gastric cancer recurrent 10.79 9.65 4 386177 17 79358190
Physical deconditioning 10.79 9.65 28 386153 2042 79356165
Deep vein thrombosis postoperative 10.78 9.65 89 386092 10663 79347544
Bone hyperpigmentation 10.78 9.65 5 386176 41 79358166
Cancer in remission 10.78 9.65 5 386176 41 79358166
Glomerulonephritis minimal lesion 10.77 9.65 16 386165 771 79357436
Demyelinating polyneuropathy 10.75 9.65 25 386156 1701 79356506
Enterocolitis haemorrhagic 10.74 9.65 29 386152 2165 79356042
Throat tightness 10.73 9.65 85 386096 27822 79330385
Phospholipidosis 10.72 9.65 9 386172 227 79357980
Acarodermatitis 10.70 9.65 22 386159 1376 79356831
Ankle fracture 10.69 9.65 44 386137 16925 79341282
Hepatic infection bacterial 10.68 9.65 5 386176 42 79358165
Nephritis bacterial 10.68 9.65 5 386176 42 79358165
Gout 10.66 9.65 73 386108 24676 79333531
SARS-CoV-2 antibody test negative 10.65 9.65 9 386172 229 79357978
Biopsy bone abnormal 10.61 9.65 4 386177 18 79358189
Steatohepatitis 10.61 9.65 18 386163 972 79357235
Skin oedema 10.61 9.65 25 386156 1716 79356491
Acute phase reaction 10.61 9.65 11 386170 365 79357842
Peptic ulcer perforation 10.59 9.65 12 386169 441 79357766
Peripheral vascular disorder 10.59 9.65 14 386167 8016 79350191
Sclerema 10.58 9.65 5 386176 43 79358164
Abscess neck 10.57 9.65 20 386161 1177 79357030
PO2 decreased 10.56 9.65 35 386146 2928 79355279
Paracoccidioides infection 10.55 9.65 6 386175 78 79358129
Optic neuropathy 10.55 9.65 39 386142 3445 79354762
Monocyte percentage decreased 10.55 9.65 10 386171 297 79357910
Dysarthria 10.54 9.65 248 385933 67374 79290833
Burkitt's lymphoma 10.54 9.65 7 386174 122 79358085
Gynaecomastia 10.53 9.65 13 386168 7668 79350539
Tonic convulsion 10.53 9.65 29 386152 2191 79356016
Microangiopathy 10.52 9.65 26 386155 1839 79356368
Snoring 10.52 9.65 7 386174 5559 79352648
Blood immunoglobulin M decreased 10.49 9.65 21 386160 1288 79356919
Plasminogen decreased 10.48 9.65 3 386178 4 79358203
Anal cancer 10.46 9.65 16 386165 791 79357416
Sputum discoloured 10.46 9.65 62 386119 21681 79336526
Influenza B virus test positive 10.46 9.65 11 386170 371 79357836
Normochromic anaemia 10.46 9.65 12 386169 447 79357760
Hepatitis C antibody positive 10.46 9.65 9 386172 235 79357972
Dysstasia 10.45 9.65 85 386096 27661 79330546
Pyloric stenosis 10.44 9.65 13 386168 528 79357679
Crystal urine 10.44 9.65 7 386174 124 79358083
Portal vein stenosis 10.44 9.65 4 386177 19 79358188
Pericardiotomy 10.44 9.65 4 386177 19 79358188
Umbilical cord vascular disorder 10.44 9.65 4 386177 19 79358188
Asthma 10.44 9.65 541 385640 134554 79223653
Meningococcal sepsis 10.42 9.65 6 386175 80 79358127
Thyroid gland abscess 10.42 9.65 6 386175 80 79358127
Uterine enlargement 10.39 9.65 17 386164 891 79357316
Alpha haemolytic streptococcal infection 10.38 9.65 30 386151 2330 79355877
Histiocytosis 10.38 9.65 5 386176 45 79358162
Acne 10.37 9.65 83 386098 27107 79331100
Paratracheal lymphadenopathy 10.37 9.65 8 386173 178 79358029
Purulent pericarditis 10.36 9.65 6 386175 81 79358126
Gastrointestinal pain 10.33 9.65 20 386161 9835 79348372
Urine output decreased 10.31 9.65 133 386048 17889 79340318
Blindness 10.31 9.65 194 385987 28189 79330018
Omental necrosis 10.29 9.65 5 386176 46 79358161
Renal and pancreas transplant rejection 10.29 9.65 5 386176 46 79358161
Microembolism 10.29 9.65 5 386176 46 79358161
Mucosal disorder 10.27 9.65 39 386142 3489 79354718
Cholecystitis acute 10.27 9.65 105 386076 13346 79344861
Splenic peliosis 10.27 9.65 4 386177 20 79358187
Knee operation 10.27 9.65 8 386173 5858 79352349
Malignant neoplasm of orbit 10.27 9.65 4 386177 20 79358187
Odontogenic cyst 10.27 9.65 4 386177 20 79358187
Camptodactyly-arthropathy-coxa vara-pericarditis syndrome 10.27 9.65 4 386177 20 79358187
Disseminated aspergillosis 10.27 9.65 19 386162 1099 79357108
Acute interstitial pneumonitis 10.26 9.65 20 386161 1203 79357004
Moraxella infection 10.26 9.65 14 386167 623 79357584
Hepatomegaly 10.26 9.65 138 386043 18736 79339471
Superinfection 10.25 9.65 49 386132 4853 79353354
Meningitis aseptic 10.25 9.65 63 386118 6865 79351342
Haematochezia 10.25 9.65 521 385660 87124 79271083
Diabetic neuropathy 10.24 9.65 9 386172 6207 79352000
Abdominal lymphadenopathy 10.22 9.65 21 386160 1313 79356894
Placental insufficiency 10.21 9.65 19 386162 1104 79357103
Paraplegia 10.20 9.65 50 386131 5003 79353204
Infective aortitis 10.19 9.65 5 386176 47 79358160
Human herpes virus 8 test positive 10.19 9.65 5 386176 47 79358160
Mesenteric arterial occlusion 10.17 9.65 9 386172 244 79357963
Transfusion 10.17 9.65 61 386120 21269 79336938
Telangiectasia 10.16 9.65 22 386159 1427 79356780
Paranasal sinus hypersecretion 10.15 9.65 3 386178 3843 79354364
Facial bones fracture 10.14 9.65 6 386175 5076 79353131
Orchitis 10.14 9.65 21 386160 1320 79356887
Cardiac pacemaker insertion 10.12 9.65 8 386173 5814 79352393
Parophthalmia 10.11 9.65 11 386170 386 79357821
Gamma-glutamyltransferase 10.10 9.65 5 386176 48 79358159
Prepyloric stenosis 10.09 9.65 3 386178 5 79358202
Accident 10.08 9.65 17 386164 8814 79349393
Hepatic neoplasm 10.08 9.65 38 386143 3388 79354819
Pseudo-Bartter syndrome 10.05 9.65 6 386175 86 79358121
Chest expansion decreased 10.04 9.65 8 386173 187 79358020
Hunger 10.03 9.65 7 386174 5421 79352786
Brucellosis 10.02 9.65 7 386174 133 79358074
High density lipoprotein decreased 10.01 9.65 5 386176 4650 79353557
Paraspinal abscess 10.00 9.65 8 386173 188 79358019
Disseminated blastomycosis 10.00 9.65 8 386173 188 79358019
Metastases to abdominal wall 9.97 9.65 8 386173 189 79358018
Oesophageal rupture 9.97 9.65 17 386164 922 79357285
Pseudallescheria infection 9.96 9.65 4 386177 22 79358185
Tonsillar exudate 9.96 9.65 4 386177 22 79358185
Gastrointestinal ulcer 9.96 9.65 38 386143 3408 79354799
T-lymphocyte count decreased 9.96 9.65 13 386168 554 79357653
Hair colour changes 9.96 9.65 4 386177 4228 79353979
Transitional cell carcinoma 9.95 9.65 31 386150 2510 79355697
Disseminated mucormycosis 9.94 9.65 15 386166 733 79357474
Pericoronitis 9.93 9.65 5 386176 50 79358157
Injection site irritation 9.92 9.65 3 386178 3787 79354420
Blood thyroid stimulating hormone increased 9.92 9.65 20 386161 9688 79348519
Intraocular pressure test abnormal 9.89 9.65 7 386174 136 79358071
Metastatic squamous cell carcinoma 9.87 9.65 13 386168 559 79357648
Parvovirus B19 test positive 9.84 9.65 7 386174 137 79358070
Remission not achieved 9.84 9.65 11 386170 398 79357809
Skin neoplasm excision 9.84 9.65 18 386163 1032 79357175
Squamous cell carcinoma of the tongue 9.83 9.65 15 386166 740 79357467
Immune-mediated myositis 9.83 9.65 38 386143 3429 79354778
Scar 9.83 9.65 39 386142 15157 79343050
Micturition urgency 9.82 9.65 30 386151 12611 79345596
Drug level changed 9.82 9.65 13 386168 562 79357645
Kaposi sarcoma inflammatory cytokine syndrome 9.81 9.65 4 386177 23 79358184
Silicosis 9.81 9.65 4 386177 23 79358184
Angioimmunoblastic T-cell lymphoma stage IV 9.81 9.65 4 386177 23 79358184
Injection site extravasation 9.81 9.65 20 386161 9649 79348558
Fulminant type 1 diabetes mellitus 9.81 9.65 22 386159 1461 79356746
Corneal endotheliitis 9.81 9.65 6 386175 90 79358117
VIth nerve paresis 9.80 9.65 7 386174 138 79358069
Upper motor neurone lesion 9.78 9.65 9 386172 257 79357950
Product physical issue 9.78 9.65 4 386177 4181 79354026
Granuloma skin 9.78 9.65 77 386104 9097 79349110
Oxygen consumption increased 9.77 9.65 6 386175 4973 79353234
HIV associated nephropathy 9.76 9.65 10 386171 327 79357880
Depressive symptom 9.76 9.65 10 386171 6413 79351794
Rhinovirus infection 9.75 9.65 69 386112 7884 79350323
Urethral polyp 9.74 9.65 3 386178 6 79358201
Eosinophil percentage abnormal 9.74 9.65 3 386178 6 79358201
Dermatopathic lymphadenopathy 9.74 9.65 3 386178 6 79358201
Oesophagectomy 9.74 9.65 3 386178 6 79358201
Anaplastic large cell lymphoma T- and null-cell types stage III 9.74 9.65 3 386178 6 79358201
Bowenoid papulosis 9.74 9.65 3 386178 6 79358201
Leukaemia cutis 9.72 9.65 8 386173 196 79358011
PCO2 increased 9.70 9.65 25 386156 1815 79356392
Oesophagopleural fistula 9.68 9.65 5 386176 53 79358154
Infective scleritis 9.68 9.65 5 386176 53 79358154
Cardiac flutter 9.68 9.65 6 386175 4948 79353259

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A01AC04 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Corticosteroids for local oral treatment
ATC A01AC54 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Corticosteroids for local oral treatment
ATC A07EA01 ALIMENTARY TRACT AND METABOLISM
ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
INTESTINAL ANTIINFLAMMATORY AGENTS
Corticosteroids acting locally
ATC C05AA04 CARDIOVASCULAR SYSTEM
VASOPROTECTIVES
AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Corticosteroids
ATC D07AA03 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, PLAIN
Corticosteroids, weak (group I)
ATC D07BA01 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
Corticosteroids, weak, combinations with antiseptics
ATC D07CA03 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
Corticosteroids, weak, combinations with antibiotics
ATC D07XA02 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, OTHER COMBINATIONS
Corticosteroids, weak, other combinations
ATC H02AB06 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Glucocorticoids
ATC R01AD02 RESPIRATORY SYSTEM
NASAL PREPARATIONS
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
Corticosteroids
ATC R01AD52 RESPIRATORY SYSTEM
NASAL PREPARATIONS
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
Corticosteroids
ATC S01BA04 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS
Corticosteroids, plain
ATC S01BB02 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS
Corticosteroids and mydriatics in combination
ATC S01CA02 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
ATC S01CB02 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids/antiinfectives/mydriatics in combination
ATC S02BA03 SENSORY ORGANS
OTOLOGICALS
CORTICOSTEROIDS
Corticosteroids
ATC S02CA01 SENSORY ORGANS
OTOLOGICALS
CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
ATC S03BA02 SENSORY ORGANS
OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
CORTICOSTEROIDS
Corticosteroids
ATC S03CA02 SENSORY ORGANS
OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
ATC V03AB05 VARIOUS
ALL OTHER THERAPEUTIC PRODUCTS
ALL OTHER THERAPEUTIC PRODUCTS
Antidotes
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D006728 Hormones
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018931 Antineoplastic Agents, Hormonal
MeSH PA D005938 Glucocorticoids
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:35705 immunosuppressive agents
CHEBI has role CHEBI:37962 adrenergic agents
CHEBI has role CHEBI:49103 drug metabolites
CHEBI has role CHEBI:78298 environmental contaminants

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Disorder of musculoskeletal system indication 928000 DOID:17
Cerebral edema indication 2032001
Keratitis indication 5888003 DOID:4677
Berylliosis indication 8247009 DOID:10322
Psoriasis indication 9014002 DOID:8893
Ankylosing spondylitis indication 9631008 DOID:7147
Cyclitis indication 17657000
Rheumatic heart disease indication 23685000
Atopic dermatitis indication 24079001 DOID:3310
Inflammatory bowel disease indication 24526004 DOID:0050589
Multiple sclerosis indication 24700007 DOID:2377
Severe adrenal insufficiency indication 24867002
Sarcoidosis indication 31541009 DOID:11335
Idiopathic thrombocytopenic purpura indication 32273002 DOID:8924
Psoriasis with arthropathy indication 33339001
Crohn's disease indication 34000006
Tendinitis indication 34840004 DOID:971
Erythema multiforme indication 36715001
Extrinsic allergic alveolitis indication 37471005 DOID:841
Allergic bronchopulmonary aspergillosis indication 37981002 DOID:13166
Contact dermatitis indication 40275004 DOID:2773
Angioedema indication 41291007 DOID:1558
Miliary tuberculosis indication 47604008 DOID:9861
Humoral hypercalcemia of malignancy indication 47709007
Articular gout indication 48440001 DOID:13189
Seborrheic dermatitis indication 50563003 DOID:8741
Edema of larynx indication 51599000
Fibrosis of lung indication 51615001 DOID:3770
Nephrotic syndrome indication 52254009 DOID:1184
Lichen simplex chronicus indication 53891004
Systemic lupus erythematosus indication 55464009 DOID:9074
Allergic rhinitis indication 61582004
Ulcerative colitis indication 64766004 DOID:8577
Löffler's syndrome indication 64936001 DOID:9503
Iritis indication 65074000 DOID:1406
Pemphigus indication 65172003 DOID:9182
Polymyalgia rheumatica indication 65323003 DOID:853
Granuloma annulare indication 65508009 DOID:3777
Tenosynovitis indication 67801009 DOID:970
Blepharoconjunctivitis indication 68659002 DOID:2456
Rheumatoid arthritis indication 69896004 DOID:7148
Transfusion reaction due to serum protein reaction indication 72284000
Stevens-Johnson syndrome indication 73442001 DOID:0050426
Epicondylitis indication 73583000 DOID:14087
Acquired thrombocytopenia indication 74576004 DOID:11126
Sympathetic uveitis indication 75315001 DOID:12029
Iridocyclitis indication 77971008
Thyroiditis indication 82119001 DOID:7166
Sjögren's syndrome indication 83901003 DOID:12894
Bursitis indication 84017003 DOID:2965
Dacryocystitis indication 85777005 DOID:9938
Autoimmune disease indication 85828009
Corneal abrasion indication 85848002
Congenital hypoplastic anemia indication 88854002 DOID:1339
Pruritus ani indication 90446007
Corneal ulcer indication 91514001 DOID:8463
Acute lymphoid leukemia indication 91857003 DOID:9952
Disorder of skin indication 95320005 DOID:37
Dermatitis herpetiformis indication 111196000 DOID:8505
Hodgkin's disease indication 118599009
Non-Hodgkin's lymphoma indication 118601006
Mycosis fungoides indication 118618005
Bacterial conjunctivitis indication 128350005 DOID:9700
Uveitis indication 128473001 DOID:13141
Aspiration pneumonitis indication 155597006
Asthma indication 195967001 DOID:2841
Ocular rosacea indication 200933006
Discoid lupus erythematosus indication 200938002
Plaque psoriasis indication 200965009
Transplanted organ rejection indication 213148006
Congenital adrenal hyperplasia indication 237751000
Scalp psoriasis indication 238608008
Punctate keratopathy indication 246936005
Adrenogenital disorder indication 267395000 DOID:0050811
Pruritus of genital organs indication 267802000
Eruption of skin indication 271807003 DOID:0050486
Exacerbation of asthma indication 281239006
Follicular non-Hodgkin's lymphoma indication 308121000
Meibomianitis indication 309779001
Infective blepharitis indication 312219000
Bacterial keratitis indication 314557000
Eosinophilic asthma indication 367542003 DOID:9498
Disorder of eye indication 371405004 DOID:5614
Primary adrenocortical insufficiency indication 373662000
Adrenal cortical hypofunction indication 386584007 DOID:10493
Herpes zoster keratitis indication 397573005
Rosacea indication 398909004 DOID:8881
Erythroderma indication 399992009
Primary cutaneous T-cell lymphoma indication 400122007
Juvenile rheumatoid arthritis indication 410795001
Autoimmune hemolytic anemia indication 413603009 DOID:718
Giant cell arteritis indication 414341000 DOID:13375
Pneumocystosis jiroveci pneumonia indication 415125002 DOID:11339
Synovitis indication 416209007 DOID:2703
Allergic conjunctivitis indication 473460002 DOID:11204
Post traumatic osteoarthritis indication 699262001
Diagnostic Test for Cushing's Syndrome indication
Severe Ocular Inflammation indication
Progressive Diffuse Large B-Cell Lymphoma indication
Superficial Ocular Infection indication
Post-Op Ocular Inflammation indication
Systemic Dermatomyositis indication
Synovitis due to Osteoarthritis indication
Erythroblastic Anemia indication
Transfusion Reaction Urticaria indication
Otitis externa off-label use 3135009
Pericarditis off-label use 3238004 DOID:1787
Chronic obstructive lung disease off-label use 13645005 DOID:3083
Pulmonary edema off-label use 19242006 DOID:11396
Shock off-label use 27942005
West syndrome off-label use 28055006
Vasculitis off-label use 31996006 DOID:865
Bronchitis off-label use 32398004 DOID:6132
Anaphylaxis off-label use 39579001
Eczema off-label use 43116000
Respiratory distress syndrome in the newborn off-label use 46775006
Nasal polyp off-label use 52756005
Rheumatic fever off-label use 58718002 DOID:1586
Pseudogout off-label use 60782007
Chronic hepatitis off-label use 76783007 DOID:2237
Pemphigoid off-label use 86142006
Hepatic necrosis off-label use 87248009
Myasthenia gravis off-label use 91637004 DOID:437
Multiple myeloma off-label use 109989006 DOID:9538
Polyarteritis nodosa off-label use 155441006 DOID:9810
Bell's palsy off-label use 193093009 DOID:12506
Celiac disease off-label use 396331005 DOID:10608
Carditis off-label use 399617002
Allergic otitis externa off-label use 405821001
Neuroendocrine Prostate Carcinoma off-label use
Otitis Externa Seborrhea off-label use
Prevention of Cytarabine-Induced Keratoconjunctivitis off-label use
Prevention of Post-Extubation Laryngeal Edema off-label use
Prevention of Lung Transplant Rejection off-label use
Obstructive Bronchiolitis off-label use
Neonatal Bronchopulmonary Dysplasia off-label use
Metastatic Prostate Carcinoma off-label use
Prevention of Cardiac Transplant Rejection off-label use
Hypercalcemia associated with Sarcoidosis off-label use
Otitis Externa Eczema off-label use
Infection by Strongyloides contraindication 1214006 DOID:10955
Mycosis contraindication 3218000 DOID:1564
Ocular hypertension contraindication 4210003 DOID:9282
Gastritis contraindication 4556007 DOID:4029
Herpes simplex keratitis contraindication 9389005
Inactive tuberculosis contraindication 11999007
Peptic ulcer contraindication 13200003 DOID:750
Hypercholesterolemia contraindication 13644009
Measles contraindication 14189004 DOID:8622
Cirrhosis of liver contraindication 19943007 DOID:5082
Arginase deficiency contraindication 23501004 DOID:9278
Herpes simplex dendritic keratitis contraindication 29943008
Fungal infection of eye contraindication 31194008
Severe myopia contraindication 34187009
Immunosuppression contraindication 38013005
Hypertensive disorder contraindication 38341003 DOID:10763
Infectious disease contraindication 40733004
Hypothyroidism contraindication 40930008 DOID:1459
Hypokalemia contraindication 43339004
Chronic heart failure contraindication 48447003
Tuberculosis of eye contraindication 49107007
Cerebral malaria contraindication 53622003 DOID:14069
Tuberculosis contraindication 56717001
Congenital hyperammonemia, type I contraindication 62522004
Osteoporosis contraindication 64859006 DOID:11476
Psychotic disorder contraindication 69322001
Diabetes mellitus contraindication 73211009 DOID:9351
Hypopituitarism contraindication 74728003 DOID:9406
Hyperglycemia contraindication 80394007 DOID:4195
Ornithine Carbamyltransferase Deficiency contraindication 80908008 DOID:9271
Open-angle glaucoma contraindication 84494001 DOID:1067
Krukenberg spindle contraindication 85430004
Muscle atrophy contraindication 88092000 DOID:767
Herpes simplex contraindication 88594005 DOID:8566
Bilateral cataracts contraindication 95722004
Anemia due to enzyme deficiency contraindication 111577008
Deficiency of glucose-6-phosphate dehydrogenase contraindication 124134002 DOID:2862
Eye infection contraindication 128351009
Seizure disorder contraindication 128613002
Bacterial infection of eye contraindication 128984004
Disorder of muscle contraindication 129565002 DOID:423
Ophthalmic herpes simplex contraindication 186542001
Skin striae contraindication 201066002
Anastomosis of intestine contraindication 235407009
Telangiectasia disorder contraindication 247479008
Edema contraindication 267038008
Pathological fracture contraindication 268029009
Diverticulitis of gastrointestinal tract contraindication 271366000
Cerebral trauma contraindication 275382005
Injury of eye region contraindication 282752000
Pregnancy, function contraindication 289908002
Varicella-zoster virus infection contraindication 309465005
Viral eye infection contraindication 312132001
Osteopenia contraindication 312894000
Vaccinia keratitis contraindication 397552005
Avascular necrosis of bone contraindication 397758007 DOID:10159
Citrullinemia contraindication 398680004 DOID:9273
Atrophoderma contraindication 399979006
Traumatic rupture of tendon contraindication 415749005
Porphyria contraindication 418470004
Exposure to varicella contraindication 444453009
Arginosuccinate Lyase Deficiency contraindication




🐶 Veterinary Drug Use

SpeciesUseRelation
Cats Infectious allergic keratitis Indication
Cats Traumatic keratitis Indication
Cats Conjunctivitis Indication
Cats Otitis externa Indication
Cats Chronic otitis externa Indication
Dogs Itching Indication
Dogs Inflammation commonly associated with most skin disorders Indication
Dogs Adjunctive therapy in various cough conditions Indication
Dogs Acute or chronic bacterial infections Indication

🐶 Veterinary products

ProductApplicantIngredients
Temaril-P Tablets Zoetis Inc. 2
Temaril-P Spansule Capsule No. 1, Temaril-P Spansule Capsule No. 2 Zoetis Inc. 2
Delta Albaplex 3x Tablets, Delta Albaplex Tablets Zoetis Inc. 3
PrednisTab Lloyd Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.18 acidic
pKa2 12.91 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
5MG PREDNISOLONE AUROBINDO PHARMA LTD A215673 March 17, 2023 RX TABLET ORAL Nov. 18, 2023 COMPETITIVE GENERIC THERAPY

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST EC50 7.80 WOMBAT-PK CHEMBL
Annexin A1 Cytosolic other WOMBAT-PK
Mineralocorticoid receptor Nuclear hormone receptor Ki 9.54 CHEMBL
Androgen receptor Nuclear hormone receptor Ki 5.60 CHEMBL
Corticosteroid-binding globulin Secreted Ki 7.51 CHEMBL
Interleukin-6 Cytokine IC50 8.38 CHEMBL
G-protein coupled bile acid receptor 1 GPCR IC50 6.60 CHEMBL
Glutamine synthetase Enzyme EC50 7.49 CHEMBL
Disintegrin and metalloproteinase domain-containing protein 17 Unclassified IC50 7.83 CHEMBL
Progesterone receptor Nuclear hormone receptor IC50 5.68 CHEMBL
Fatty acid-binding protein, liver Unclassified Ki 5.58 CHEMBL
Glucocorticoid receptor Transcription factor IC50 7.28 CHEMBL
Glucocorticoid receptor Transcription factor EC50 8.47 CHEMBL

External reference:

IDSource
4017988 VUID
N0000146334 NUI
D00472 KEGG_DRUG
4017988 VANDF
C0032950 UMLSCUI
CHEBI:8378 CHEBI
TUA PDB_CHEM_ID
CHEMBL131 ChEMBL_ID
DB00860 DRUGBANK_ID
D011239 MESH_DESCRIPTOR_UI
5755 PUBCHEM_CID
2866 IUPHAR_LIGAND_ID
535 INN_ID
9PHQ9Y1OLM UNII
8638 RXNORM
5347 MMSL
59710 MMSL
d00084 MMSL
002155 NDDF
116601002 SNOMEDCT_US
52388000 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
PrednisoLONE HUMAN PRESCRIPTION DRUG LABEL 1 0527-5406 SYRUP 15 mg ORAL ANDA 14 sections
PrednisoLONE HUMAN PRESCRIPTION DRUG LABEL 1 0527-5406 SYRUP 15 mg ORAL ANDA 14 sections
PrednisoLONE HUMAN PRESCRIPTION DRUG LABEL 1 0527-5406 SYRUP 15 mg ORAL ANDA 14 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 12634-686 SOLUTION 15 mg ORAL ANDA 11 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 16590-291 SOLUTION 15 mg ORAL ANDA 11 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 21695-365 SOLUTION 15 mg ORAL ANDA 12 sections
MILLIPRED HUMAN PRESCRIPTION DRUG LABEL 1 23594-505 TABLET 5 mg ORAL ANDA 13 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 33261-475 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50090-0655 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50090-0655 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50090-0655 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50090-0655 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50383-042 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50383-042 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50383-042 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 53217-193 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 54868-4748 SYRUP 5 mg ORAL ANDA 10 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 54868-4749 SYRUP 15 mg ORAL ANDA 10 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 58177-910 SYRUP 15 mg ORAL ANDA 10 sections
PREDNISOLONE Human Prescription Drug Label 1 59651-491 TABLET 5 mg ORAL ANDA 11 sections
PREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 61919-291 SOLUTION 15 mg ORAL ANDA 10 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 62135-250 SOLUTION 15 mg ORAL ANDA 10 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 62135-250 SOLUTION 15 mg ORAL ANDA 10 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 62135-437 TABLET 5 mg ORAL ANDA 11 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 63187-466 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 66116-603 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 67296-1656 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 68258-8987 SOLUTION 15 mg ORAL ANDA 12 sections
Prednisolone HUMAN PRESCRIPTION DRUG LABEL 1 68788-9096 SOLUTION 15 mg ORAL ANDA 12 sections
CAMBISON HUMAN OTC DRUG LABEL 2 72689-0016 OINTMENT 4 mg TOPICAL unapproved drug other 7 sections