pralmorelin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
growth hormone release-stimulating peptides	2232	158861-67-7

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

pralmorelin
pralmorelin hydrochloride
GHRP-2
pralmorelin dihydrochloride
KP-102
GHRP
KP-102D
pralmorelin HCl

Molecular weight: 817.99
Formula: C45H55N9O6
CLOGP: 0.28
LIPINSKI: 3
HAC: 15
HDO: 9
TPSA: 256.42
ALOGS: -5.72
ROTB: 21

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Oct. 22, 2004	PMDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D006133	Growth Substances

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Growth hormone releasing hormone test	indication	252202002

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	12.59	acidic
pKa2	13.08	acidic
pKa3	13.13	acidic
pKa4	13.56	acidic
pKa5	10.31	Basic
pKa6	7.91	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Growth hormone secretagogue receptor type 1	GPCR	Q92847	GHSR_HUMAN	AGONIST				UNKNOWN	SCIENTIFIC LITERATURE
Growth hormone secretagogue receptor type 1	GPCR		GHSR_RAT	AGONIST	Ki	9.30		IUPHAR

External reference:

ID	Source
D02040	KEGG_DRUG
158827-34-0	SECONDARY_CAS_RN
C0293969	UMLSCUI
CHEBI:135890	CHEBI
CHEMBL106593	ChEMBL_ID
1092	IUPHAR_LIGAND_ID
C091874	MESH_SUPPLEMENTAL_RECORD_UI
7604	INN_ID
E6S6E1F19M	UNII
6918245	PUBCHEM_CID
1492038	RXNORM
CHEMBL2105772	ChEMBL_ID

Pharmaceutical products:

None