pralmorelin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
growth hormone release-stimulating peptides 2232 158861-67-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pralmorelin
  • pralmorelin hydrochloride
  • GHRP-2
  • pralmorelin dihydrochloride
  • KP-102
  • GHRP
  • KP-102D
  • pralmorelin HCl
  • Molecular weight: 817.99
  • Formula: C45H55N9O6
  • CLOGP: 0.28
  • LIPINSKI: 3
  • HAC: 15
  • HDO: 9
  • TPSA: 256.42
  • ALOGS: -5.72
  • ROTB: 21

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Oct. 22, 2004 PMDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D006133 Growth Substances

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Growth hormone releasing hormone test indication 252202002




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.59 acidic
pKa2 13.08 acidic
pKa3 13.13 acidic
pKa4 13.56 acidic
pKa5 10.31 Basic
pKa6 7.91 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Growth hormone secretagogue receptor type 1 GPCR AGONIST UNKNOWN SCIENTIFIC LITERATURE
Growth hormone secretagogue receptor type 1 GPCR AGONIST Ki 9.30 IUPHAR

External reference:

IDSource
D02040 KEGG_DRUG
158827-34-0 SECONDARY_CAS_RN
C0293969 UMLSCUI
CHEBI:135890 CHEBI
CHEMBL106593 ChEMBL_ID
1092 IUPHAR_LIGAND_ID
C091874 MESH_SUPPLEMENTAL_RECORD_UI
7604 INN_ID
E6S6E1F19M UNII
6918245 PUBCHEM_CID
1492038 RXNORM
CHEMBL2105772 ChEMBL_ID

Pharmaceutical products:

None