pivampicillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 2218 33817-20-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pivampicillin
  • pivaloylampicillin
  • pivaloyloxymethyl ampicillinate
  • ampicillin pivaloyloxymethyl ester
Pivalate ester analog of AMPICILLIN.
  • Molecular weight: 463.55
  • Formula: C22H29N3O6S
  • CLOGP: 2.52
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 2
  • TPSA: 128.03
  • ALOGS: -4.12
  • ROTB: 9

Drug dosage:

DoseUnitRoute
1.05 g O

ADMET properties:

PropertyValueReference
BA (Bioavailability) 30.90 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01CA02 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Penicillins with extended spectrum
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:50266 Prodrugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.17 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000166997 NUI
D08396 KEGG_DRUG
C0032032 UMLSCUI
CHEBI:8255 CHEBI
CHEMBL3182343 ChEMBL_ID
CHEMBL323354 ChEMBL_ID
D010917 MESH_DESCRIPTOR_UI
DB01604 DRUGBANK_ID
2864 INN_ID
0HLM346LL7 UNII
33478 PUBCHEM_CID
8372 RXNORM
003897 NDDF
387545005 SNOMEDCT_US
96072001 SNOMEDCT_US

Pharmaceutical products:

None