Molfile
Inchi
Smiles
Synonyms:
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pimozide
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primozide
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R6238
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R-6238
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A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
- Molecular weight: 461.56
- Formula: C28H29F2N3O
- CLOGP: 6.40
- LIPINSKI: 1
- HAC: 4
- HDO: 1
- TPSA: 35.58
- ALOGS: -5.43
- ROTB: 7
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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