pholcodine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2154 509-67-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pholcodine
  • biocalyptol
  • codylin
  • ethnine
  • folcodin
  • folcodine
  • galenphol
  • galphol
  • glycodine
  • homocodeine
  • morpholinylethylmorphine
  • neocodine
  • o-2-morpholinoethylmorphine
  • o3-(2-morpholinoethyl)morphine
  • pholtex
  • weifacodine
  • beta-morpholinylethylmorphine
  • Molecular weight: 398.50
  • Formula: C23H30N2O4
  • CLOGP: 1.07
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 54.40
  • ALOGS: -2.91
  • ROTB: 4

Drug dosage:

DoseUnitRoute
50 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R05DA08 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Opium alkaloids and derivatives
MeSH PA D000700 Analgesics
MeSH PA D000996 Antitussive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D019141 Respiratory System Agents
MeSH PA D018689 Sensory System Agents
CHEBI has role CHEBI:35482 narcotic analgesic
CHEBI has role CHEBI:51177 anti-tussive
CHEBI has role CHEBI:55322 mu-opioid agonists
CHEBI has role CHEBI:88188 allergenic drug

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.38 Basic
pKa2 6.85 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07385 KEGG_DRUG
C0070742 UMLSCUI
CHEBI:53579 CHEBI
CHEMBL2105224 ChEMBL_ID
DB09209 DRUGBANK_ID
C008872 MESH_SUPPLEMENTAL_RECORD_UI
5311356 PUBCHEM_CID
9086 IUPHAR_LIGAND_ID
272 INN_ID
LPP64AWZ7L UNII
33431 RXNORM
004023 NDDF
320972003 SNOMEDCT_US
396486005 SNOMEDCT_US

Pharmaceutical products:

None