ancitabine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
nucleosides antiviral or antineoplastic agents, cytarabine or azacitidine derivatives 212 31698-14-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ancitabine
  • ancytabine
  • cyclocytidine
Congener of CYTARABINE that is metabolized to cytarabine and thereby maintains a more constant antineoplastic action.
  • Molecular weight: 225.20
  • Formula: C9H11N3O4
  • CLOGP: -2.75
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 98.37
  • ALOGS: -1.85
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000963 Antimetabolites
MeSH PA D000964 Antimetabolites, Antineoplastic
MeSH PA D000970 Antineoplastic Agents
MeSH PA D009676 Noxae
CHEBI has role CHEBI:35221 antimetabolite
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:50266 Prodrugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.69 acidic
pKa2 9.39 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0010557 UMLSCUI
CHEBI:74838 CHEBI
CHEMBL1412614 ChEMBL_ID
D003504 MESH_DESCRIPTOR_UI
25051 PUBCHEM_CID
3992 INN_ID
DO2D32W0VC UNII

Pharmaceutical products:

None