DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
periciazine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
2107
2622-26-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
periciazine
nelactil
nemactil
neulactil
periciazinum
pericyazine
properciazine
propericiazine
propericyazine
Molecular weight: 365.50
Formula: C21H23N3OS
CLOGP: 3.44
LIPINSKI: 0
HAC: 4
HDO: 1
TPSA: 50.50
ALOGS: -3.79
ROTB: 4
Drug dosage:
Dose
Unit
Route
50
mg
O
20
mg
P
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Resting tremor
61.62
52.60
9
267
814
63487932
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FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Resting tremor
53.80
46.31
9
436
1512
79742431
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FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N05AC01
NERVOUS SYSTEM
PSYCHOLEPTICS
ANTIPSYCHOTICS
Phenothiazines with piperidine structure
CHEBI has role
CHEBI:35717
hypnotics
CHEBI has role
CHEBI:37887
adrenergic blockers
CHEBI has role
CHEBI:65190
typical antipsychotic drugs
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.84
Basic
pKa2
2.39
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
D(1A) dopamine receptor
GPCR
P21728
DRD1_HUMAN
ANTAGONIST
Ki
8
IUPHAR
Androgen receptor
Transcription factor
ANDR_RAT
Ki
5.52
CHEMBL
Acetylcholinesterase
Enzyme
ACES_BOVIN
IC50
5.15
CHEMBL
Cholinesterase
Enzyme
CHLE_HORSE
IC50
6.64
CHEMBL
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External reference:
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ID
Source
003467
NDDF
1398
INN_ID
321467007
SNOMEDCT_US
3405M6FD73
UNII
395825007
SNOMEDCT_US
4747
PUBCHEM_CID
8766
RXNORM
9216
IUPHAR_LIGAND_ID
C0033459
UMLSCUI
C084584
MESH_SUPPLEMENTAL_RECORD_UI
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Pharmaceutical products:
None
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periciazine