pentetic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2092 67-43-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pentetic acid
  • detapac
  • detarex
  • diethylenetriaminepentaacetic acid
An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
  • Molecular weight: 393.35
  • Formula: C14H23N3O10
  • CLOGP: -2.91
  • LIPINSKI: 1
  • HAC: 13
  • HDO: 5
  • TPSA: 196.22
  • ALOGS: -1.97
  • ROTB: 16

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000931 Antidotes
MeSH PA D002614 Chelating Agents
MeSH PA D007502 Iron Chelating Agents
MeSH PA D020011 Protective Agents
MeSH PA D064449 Sequestering Agents
FDA MoA N0000175962 Lead Chelating Activity
FDA EPC N0000175963 Lead Chelator
CHEBI has role CHEBI:166831 copper chelator

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.82 acidic
pKa2 1.26 acidic
pKa3 1.84 acidic
pKa4 2.15 acidic
pKa5 2.75 acidic
pKa6 10.13 Basic
pKa7 9.11 Basic
pKa8 4.37 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019580 VUID
N0000147679 NUI
D05422 KEGG_DRUG
4018190 VANDF
4019580 VANDF
C0013254 UMLSCUI
CHEBI:35739 CHEBI
CHEMBL780 ChEMBL_ID
D004369 MESH_DESCRIPTOR_UI
DB14007 DRUGBANK_ID
3053 PUBCHEM_CID
6596 INN_ID
7A314HQM0I UNII
3690 RXNORM
194369 MMSL
28970 MMSL
d07922 MMSL
006655 NDDF
009768 NDDF
429352009 SNOMEDCT_US
429461005 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
DRAXIMAGE DTPA HUMAN PRESCRIPTION DRUG LABEL 1 65174-288 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 20 mg INTRAVENOUS NDA 21 sections
DRAXIMAGE DTPA HUMAN PRESCRIPTION DRUG LABEL 1 65174-288 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 20 mg INTRAVENOUS NDA 21 sections
DRAXIMAGE DTPA HUMAN PRESCRIPTION DRUG LABEL 1 65174-288 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 20 mg INTRAVENOUS NDA 21 sections
DRAXIMAGE DTPA HUMAN PRESCRIPTION DRUG LABEL 1 65174-288 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 20 mg INTRAVENOUS NDA 21 sections