calcium pantothenate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	2055	79-83-4

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: calcium pantothenate pantothenic acid (+)-Pantothenic acid D-Pantothenic acid Vitamin B5	A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE. Molecular weight: 219.24 Formula: C9H17NO5 CLOGP: -1.49 LIPINSKI: 0 HAC: 6 HDO: 4 TPSA: 106.86 ALOGS: -0.56 ROTB: 6 Status: OFM Legend: OFP - off patent OFM - off market ONP - on patent

Molecule

Description

Molfile Inchi Smiles

Synonyms:

calcium pantothenate
pantothenic acid
(+)-Pantothenic acid
D-Pantothenic acid
Vitamin B5

A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.

Molecular weight: 219.24
Formula: C9H17NO5
CLOGP: -1.49
LIPINSKI: 0
HAC: 6
HDO: 4
TPSA: 106.86
ALOGS: -0.56
ROTB: 6

Status: OFM

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Dec. 29, 1993	FDA	HOSPIRA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Contraindicated product administered	129.79	11.27	3	42053	217645	63229321
Treatment failure	96.24	11.27	10	42046	199033	63247933
Synovitis	94.06	11.27	8	42048	186910	63260056
Systemic lupus erythematosus	88.05	11.27	16	42040	208902	63238064
Product use issue	86.50	11.27	20	42036	220500	63226466
Glossodynia	81.48	11.27	11	42045	178865	63268101
Product dose omission issue	80.66	11.27	338	41718	233975	63212991
Diarrhoea	78.73	11.27	770	41286	714596	62732370
Infusion related reaction	74.07	11.27	35	42021	245486	63201480
Maternal exposure during pregnancy	71.74	11.27	28	42028	220034	63226932
Pericarditis	70.92	11.27	4	42052	131575	63315391
Muscle spasms	70.81	11.27	246	41810	155904	63291062
Toxicity to various agents	69.00	11.27	39	42017	247211	63199755
Wound	61.67	11.27	16	42040	163247	63283719
Drug ineffective	60.21	11.27	426	41630	1044339	62402627
Drug intolerance	59.65	11.27	70	41986	308591	63138375
Device expulsion	58.20	11.27	92	41964	34830	63412136
Product use in unapproved indication	58.00	11.27	23	42033	179057	63267909
Unevaluable event	55.50	11.27	112	41944	51274	63395692
Off label use	55.07	11.27	245	41811	674217	62772749
Arthropathy	54.87	11.27	45	42011	234747	63212219
Fall	53.55	11.27	443	41613	391891	63055075
Full blood count decreased	48.20	11.27	72	41984	25952	63421014
Psoriasis	47.48	11.27	146	41910	86811	63360155
Helicobacter infection	46.57	11.27	4	42052	92781	63354185
Intentional product use issue	45.57	11.27	14	42042	127878	63319088
Device dislocation	44.61	11.27	69	41987	25636	63421330
Fatigue	43.32	11.27	826	41230	887202	62559764
Hepatic enzyme increased	41.11	11.27	44	42012	202284	63244682
Therapy cessation	41.09	11.27	73	41983	30384	63416582
Drug hypersensitivity	40.70	11.27	91	41965	310596	63136370
Flatulence	39.11	11.27	77	41979	34625	63412341
Lower respiratory tract infection	38.15	11.27	20	42036	132287	63314679
Dizziness	36.49	11.27	440	41616	429485	63017481
Deep vein thrombosis	36.20	11.27	130	41926	83670	63363296
Neuropathy peripheral	35.23	11.27	159	41897	113508	63333458
Asthenia	33.15	11.27	394	41662	383210	63063756
Therapeutic product effect incomplete	33.06	11.27	21	42035	125035	63321931
Folliculitis	32.78	11.27	4	42052	70313	63376653
Intentional overdose	32.72	11.27	5	42051	74147	63372819
Therapeutic product effect decreased	32.01	11.27	49	42007	193138	63253828
Nausea	31.95	11.27	765	41291	853706	62593260
Feeling abnormal	31.01	11.27	186	41870	148206	63298760
C-reactive protein increased	30.92	11.27	12	42044	94695	63352271
Memory impairment	30.21	11.27	143	41913	104115	63342851
General physical health deterioration	29.75	11.27	55	42001	201347	63245619
Hypoaesthesia	29.60	11.27	202	41854	168191	63278775
Constipation	29.55	11.27	252	41804	224691	63222275
Plasma cell myeloma	29.37	11.27	70	41986	35835	63411131
Discomfort	29.14	11.27	41	42015	167333	63279633
Joint swelling	28.49	11.27	116	41940	327550	63119416
Pneumonia	28.32	11.27	442	41614	456325	62990641
Drug interaction	26.92	11.27	71	41985	229060	63217906
Laboratory test abnormal	25.94	11.27	56	42000	26856	63420110
Headache	24.84	11.27	571	41485	632670	62814296
Depression	24.17	11.27	217	41839	196275	63250691
Haemoglobin decreased	24.08	11.27	172	41884	145313	63301653
Injection site pain	22.97	11.27	156	41900	129644	63317322
Dry skin	22.67	11.27	86	41970	56801	63390165
Exposure during pregnancy	21.64	11.27	44	42012	155503	63291463
Alopecia	21.60	11.27	133	41923	337403	63109563
Suicide attempt	21.10	11.27	7	42049	60911	63386055
Blister	20.48	11.27	34	42022	129780	63317186
Pelvic pain	20.32	11.27	34	42022	13485	63433481
Irritable bowel syndrome	20.23	11.27	15	42041	82397	63364569
Overdose	20.21	11.27	28	42028	115050	63331916
Paraesthesia	20.15	11.27	175	41881	156791	63290175
Hot flush	20.11	11.27	77	41979	51082	63395884
Dehydration	20.07	11.27	189	41867	173165	63273801
Eye swelling	19.96	11.27	47	42009	23871	63423095
Injection site haemorrhage	19.45	11.27	47	42009	24267	63422699
COVID-19	19.39	11.27	28	42028	113075	63333891
Liver injury	19.21	11.27	8	42048	60512	63386454
Hypersensitivity	18.89	11.27	115	41941	292570	63154396
Fluid retention	18.86	11.27	84	41972	59602	63387364
Back pain	18.84	11.27	262	41794	263883	63183083
Blepharospasm	17.95	11.27	21	42035	5975	63440991
Type 2 diabetes mellitus	17.90	11.27	10	42046	63858	63383108
Dyspnoea	17.81	11.27	568	41488	660745	62786221
Ill-defined disorder	17.48	11.27	17	42039	81738	63365228
Taste disorder	17.47	11.27	32	42024	13630	63433336
Injection site erythema	17.20	11.27	104	41952	83070	63363896
Influenza like illness	16.76	11.27	88	41968	66736	63380230
Pulmonary embolism	16.52	11.27	133	41923	116551	63330415
Condition aggravated	16.33	11.27	179	41877	402038	63044928
Nasal congestion	16.14	11.27	86	41970	65574	63381392
Urinary tract infection	15.93	11.27	255	41801	264429	63182537
Abdominal distension	15.86	11.27	105	41951	86510	63360456
Hip fracture	15.62	11.27	49	42007	29425	63417541
Infection	15.33	11.27	89	41967	229084	63217882
Pulmonary arterial hypertension	15.31	11.27	41	42015	22536	63424430
Rheumatoid arthritis	15.21	11.27	102	41954	253717	63193249
Skin discolouration	14.92	11.27	57	41999	37771	63409195
Vaginal haemorrhage	14.85	11.27	46	42010	27441	63419525
Hypervolaemia	14.84	11.27	47	42009	28366	63418600
Blood potassium decreased	14.70	11.27	61	41995	41965	63405001
Mucous stools	14.62	11.27	16	42040	4232	63442734
Impaired healing	14.26	11.27	29	42027	102513	63344453
Weight decreased	14.23	11.27	260	41796	276538	63170428
Injection site reaction	13.94	11.27	76	41980	58448	63388518
Swelling	13.51	11.27	117	41939	275261	63171705
Illness	13.29	11.27	8	42048	49051	63397915
Tremor	13.28	11.27	140	41916	132099	63314867
Depressed level of consciousness	13.16	11.27	13	42043	62065	63384901
Gastrooesophageal reflux disease	12.99	11.27	108	41948	95531	63351435
Administration site swelling	12.94	11.27	9	42047	1298	63445668
Intestinal dilatation	12.85	11.27	10	42046	1712	63445254
Dyspnoea exertional	12.85	11.27	76	41980	60226	63386740
Product complaint	12.74	11.27	27	42029	12782	63434184
Fibromyalgia	12.74	11.27	21	42035	80399	63366567
Plasma cell myeloma recurrent	12.66	11.27	13	42043	3200	63443766
Asthma	12.47	11.27	43	42013	127518	63319448
Balance disorder	12.37	11.27	97	41959	84325	63362641
Adverse event	12.31	11.27	16	42040	67543	63379423
Pulmonary hypertension	12.30	11.27	53	42003	37070	63409896
Body height decreased	12.13	11.27	23	42033	10055	63436911
White blood cell count decreased	12.02	11.27	143	41913	138961	63308005
Hospice care	11.99	11.27	20	42036	7912	63439054
Hypoxia	11.88	11.27	74	41982	59718	63387248
Chest discomfort	11.79	11.27	118	41938	109851	63337115
Prescribed overdose	11.70	11.27	4	42052	34149	63412817
Hepatic function abnormal	11.64	11.27	5	42051	37137	63409829
Multiple sclerosis relapse	11.58	11.27	63	41993	48415	63398551
Intentional product misuse	11.54	11.27	14	42042	60903	63386063
Chest pain	11.50	11.27	204	41852	215755	63231211
Atrial fibrillation	11.48	11.27	123	41933	116513	63330453
Abdominal discomfort	11.40	11.27	147	41909	320738	63126228
Dysgeusia	11.36	11.27	61	41995	46649	63400317

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Off label use	74.05	12.21	113	24442	419411	34512965
Fractional exhaled nitric oxide increased	63.10	12.21	25	24530	1057	34931319
Product use in unapproved indication	55.98	12.21	8	24547	117491	34814885
Fatigue	53.51	12.21	443	24112	370210	34562166
Plasma cell myeloma	49.19	12.21	98	24457	41939	34890437
Completed suicide	48.39	12.21	6	24549	98162	34834214
Sensation of foreign body	45.86	12.21	27	24528	2756	34929620
Product dose omission issue	44.38	12.21	184	24371	119527	34812849
Plantar fasciitis	44.26	12.21	24	24531	2092	34930284
Myoglobin blood increased	43.79	12.21	27	24528	2996	34929380
Drug interaction	41.53	12.21	59	24496	225887	34706489
Full blood count decreased	39.81	12.21	56	24499	18032	34914344
Cardiac disorder	37.28	12.21	89	24466	43037	34889339
Diarrhoea	35.65	12.21	424	24131	389488	34542888
Toxicity to various agents	35.17	12.21	54	24501	200308	34732068
Laboratory test abnormal	34.71	12.21	56	24499	20335	34912041
Brain natriuretic peptide increased	34.62	12.21	30	24525	5629	34926747
Fall	34.40	12.21	252	24303	202633	34729743
Muscle spasms	34.07	12.21	123	24432	74878	34857498
Asthenia	30.50	12.21	284	24271	244967	34687409
Secretion discharge	29.63	12.21	28	24527	5877	34926499
White blood cell count decreased	29.50	12.21	139	24416	95306	34837070
Adverse drug reaction	29.17	12.21	64	24491	29278	34903098
Exostosis	28.82	12.21	25	24530	4698	34927678
Dysphonia	26.72	12.21	54	24501	23329	34909047
Viral infection	25.48	12.21	45	24510	17578	34914798
Intentional product use issue	24.37	12.21	6	24549	59810	34872566
General physical health deterioration	22.07	12.21	35	24520	128234	34804142
Psoriasis	21.45	12.21	68	24487	38744	34893632
Dizziness	20.92	12.21	240	24315	218281	34714095
Intentional product misuse	19.73	12.21	4	24551	45607	34886769
Overdose	19.61	12.21	21	24534	91038	34841338
Multiple sclerosis relapse	19.59	12.21	34	24521	13099	34919277
Gait spastic	19.03	12.21	11	24544	1085	34931291
COVID-19	18.90	12.21	16	24539	77534	34854842
Influenza	18.88	12.21	77	24478	49589	34882787
Memory impairment	18.78	12.21	70	24485	43248	34889128
Neuropathy peripheral	18.66	12.21	111	24444	83152	34849224
Needle fatigue	18.45	12.21	10	24545	871	34931505
Rash	18.43	12.21	238	24317	222514	34709862
Pneumonia	17.77	12.21	355	24200	362272	34570104
Drug ineffective	17.66	12.21	221	24334	456530	34475846
Hepatic function abnormal	17.03	12.21	5	24550	44358	34888018
Relapsing-remitting multiple sclerosis	16.81	12.21	10	24545	1040	34931336
Treatment failure	16.62	12.21	6	24549	46691	34885685
Interstitial lung disease	16.49	12.21	13	24542	65269	34867107
Hypoaesthesia	15.80	12.21	85	24470	61359	34871017
Muscle spasticity	15.66	12.21	20	24535	5868	34926508
Dyspnoea exertional	15.59	12.21	66	24489	43213	34889163
Sinusitis	15.59	12.21	64	24491	41338	34891038
Thrombosis	15.22	12.21	73	24482	50385	34881991
Coma	14.44	12.21	7	24548	45671	34886705
Constipation	14.25	12.21	153	24402	136829	34795547
Multiple organ dysfunction syndrome	14.02	12.21	20	24535	76546	34855830
Peripheral swelling	13.46	12.21	96	24459	76445	34855931
Small intestinal obstruction	13.18	12.21	31	24524	14835	34917541
Balance disorder	13.12	12.21	60	24495	40594	34891782
Micturition urgency	12.61	12.21	19	24536	6506	34925870
Flatulence	12.50	12.21	38	24517	21160	34911216
Suicide attempt	12.36	12.21	6	24549	39110	34893266
Influenza like illness	12.26	12.21	45	24510	27589	34904787

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	132.69	10.55	7	52373	245760	79446248
Toxicity to various agents	100.45	10.55	78	52302	421462	79270546
Off label use	97.95	10.55	290	52090	906925	78785083
Product dose omission issue	91.52	10.55	363	52017	247174	79444834
Product use in unapproved indication	87.06	10.55	28	52352	250331	79441677
Treatment failure	85.68	10.55	7	52373	170479	79521529
Synovitis	73.55	10.55	7	52373	150727	79541281
Device expulsion	70.52	10.55	86	52294	25775	79666233
Fall	69.27	10.55	552	51828	487077	79204931
Drug interaction	68.73	10.55	104	52276	415079	79276929
Product use issue	66.93	10.55	27	52353	209795	79482213
Drug ineffective	62.12	10.55	436	51944	1080477	78611531
Diarrhoea	60.73	10.55	861	51519	879628	78812380
Plasma cell myeloma	58.10	10.55	116	52264	53143	79638865
Dizziness	56.70	10.55	561	51819	525880	79166128
Fatigue	55.89	10.55	888	51492	928839	78763169
Asthenia	53.99	10.55	543	51837	511146	79180862
Muscle spasms	52.71	10.55	241	52139	174489	79517519
Infusion related reaction	51.79	10.55	45	52335	230192	79461816
Intentional product use issue	51.13	10.55	18	52362	152094	79539914
Systemic lupus erythematosus	48.88	10.55	10	52370	121139	79570869
Intentional overdose	46.56	10.55	7	52373	105953	79586055
Therapy cessation	46.09	10.55	86	52294	37476	79654532
Drug intolerance	45.78	10.55	64	52316	264055	79427953
Deep vein thrombosis	43.55	10.55	176	52204	120743	79571265
General physical health deterioration	41.70	10.55	73	52307	275165	79416843
Full blood count decreased	41.49	10.55	68	52312	26751	79665257
Device dislocation	39.03	10.55	65	52315	25905	79666103
COVID-19	39.00	10.55	28	52352	157646	79534362
Intentional product misuse	38.09	10.55	8	52372	95157	79596851
Glossodynia	35.11	10.55	12	52368	103325	79588683
Drug hypersensitivity	34.70	10.55	92	52288	298824	79393184
Overdose	34.62	10.55	42	52338	184164	79507844
Therapeutic product effect incomplete	33.93	10.55	26	52354	141619	79550389
Maternal exposure during pregnancy	32.79	10.55	25	52355	136513	79555495
Pericarditis	32.27	10.55	14	52366	104222	79587786
Dehydration	31.41	10.55	274	52106	247913	79444095
Pneumonia	30.72	10.55	606	51774	659640	79032368
Lower respiratory tract infection	30.60	10.55	24	52356	129196	79562812
C-reactive protein increased	30.51	10.55	24	52356	129003	79563005
Unevaluable event	30.50	10.55	93	52287	55492	79636516
Duodenal ulcer perforation	29.96	10.55	4	52376	66207	79625801
Helicobacter infection	29.73	10.55	5	52375	69699	79622309
Haemoglobin decreased	29.57	10.55	248	52132	221871	79470137
Fluid retention	29.56	10.55	107	52273	69702	79622306
Hypoaesthesia	29.28	10.55	210	52170	179142	79512866
Arthropathy	28.64	10.55	45	52335	177066	79514942
Memory impairment	28.55	10.55	147	52233	111587	79580421
Nausea	27.15	10.55	821	51559	956375	78735633
Hepatic enzyme increased	27.13	10.55	49	52331	182561	79509447
Joint swelling	27.00	10.55	98	52282	288548	79403460
Dyspnoea	26.74	10.55	744	51636	856281	78835727
Multiple sclerosis relapse	26.61	10.55	79	52301	46454	79645554
Hypervolaemia	25.87	10.55	74	52306	42616	79649392
Depression	25.21	10.55	235	52145	216555	79475453
Feeling abnormal	25.18	10.55	185	52195	159014	79532994
Flatulence	24.87	10.55	73	52307	42651	79649357
Hospice care	24.44	10.55	32	52348	10292	79681716
Suicide attempt	24.34	10.55	12	52368	82920	79609088
Depressed level of consciousness	24.11	10.55	17	52363	96635	79595373
Injection site pain	23.54	10.55	156	52224	129682	79562326
Hepatic function abnormal	22.34	10.55	10	52370	73097	79618911
Needle fatigue	21.73	10.55	11	52369	891	79691117
Gait spastic	21.49	10.55	12	52368	1185	79690823
Mental status changes	21.40	10.55	94	52286	66865	79625143
Relapsing-remitting multiple sclerosis	21.37	10.55	13	52367	1506	79690502
Influenza like illness	20.93	10.55	98	52282	71609	79620399
Pelvic pain	20.79	10.55	34	52346	13347	79678661
Headache	20.75	10.55	569	51811	653203	79038805
Weight decreased	20.33	10.55	337	52043	354861	79337147
Hip fracture	20.29	10.55	55	52325	30706	79661302
Eye swelling	20.22	10.55	50	52330	26418	79665590
Viral infection	19.99	10.55	68	52312	42948	79649060
Eosinophilia	19.91	10.55	3	52377	45342	79646666
Folliculitis	19.57	10.55	6	52374	55374	79636634
Small intestinal obstruction	19.25	10.55	50	52330	27222	79664786
Dyspnoea exertional	18.51	10.55	109	52271	86964	79605044
Illness	18.43	10.55	4	52376	46507	79645501
Wound	18.32	10.55	30	52350	116149	79575859
Pulmonary arterial hypertension	18.00	10.55	50	52330	28316	79663692
Cholestasis	17.79	10.55	6	52374	52103	79639905
Psoriasis	17.06	10.55	109	52271	89478	79602530
Nasal congestion	17.04	10.55	97	52283	76455	79615553
Blood potassium decreased	16.97	10.55	68	52312	46444	79645564
Interstitial lung disease	16.91	10.55	30	52350	112570	79579438
Blepharospasm	16.83	10.55	20	52360	5831	79686177
Coma	16.82	10.55	25	52355	100624	79591384
Constipation	16.73	10.55	270	52110	282780	79409228
Injection site erythema	16.70	10.55	98	52282	78099	79613909
Complication associated with device	16.60	10.55	36	52344	17460	79674548
Injection site haemorrhage	16.58	10.55	48	52332	27822	79664186
Drug reaction with eosinophilia and systemic symptoms	16.42	10.55	11	52369	64233	79627775
Therapeutic response decreased	16.36	10.55	12	52368	66841	79625167
Multiple organ dysfunction syndrome	16.35	10.55	34	52346	120212	79571796
Cytomegalovirus infection	16.23	10.55	4	52376	42640	79649368
Dysgeusia	15.85	10.55	77	52303	57100	79634908
Pulmonary hypertension	15.75	10.55	68	52312	48012	79643996
White blood cell count decreased	15.73	10.55	191	52189	188097	79503911
Agranulocytosis	15.70	10.55	5	52375	45025	79646983
Micturition urgency	15.58	10.55	29	52351	12612	79679396
Irritable bowel syndrome	15.45	10.55	11	52369	62230	79629778
Abdominal pain	15.28	10.55	349	52031	389220	79302788
Haematocrit decreased	15.20	10.55	80	52300	61232	79630776
Hospitalisation	15.17	10.55	110	52270	94126	79597882
Neuropathy peripheral	14.85	10.55	150	52230	141155	79550853
Condition aggravated	14.72	10.55	236	52144	500888	79191120
Pulmonary embolism	14.72	10.55	175	52205	171479	79520529
Pleural effusion	14.69	10.55	153	52227	145109	79546899
Abdominal distension	14.55	10.55	131	52249	119519	79572489
Product complaint	14.46	10.55	29	52351	13320	79678688
Cytokine release syndrome	14.46	10.55	3	52377	35995	79656013
Taste disorder	14.38	10.55	32	52348	15791	79676217
Hypoxia	14.11	10.55	116	52264	103127	79588881
Back pain	14.02	10.55	279	52101	303901	79388107
Pollakiuria	13.97	10.55	55	52325	37262	79654746
Anxiety	13.92	10.55	235	52145	248277	79443731
Therapeutic product effect decreased	13.80	10.55	58	52322	163805	79528203
Cellulitis	13.57	10.55	120	52260	108940	79583068
Oedema peripheral	13.56	10.55	237	52143	252051	79439957
Cardiac failure congestive	13.48	10.55	148	52232	142254	79549754
Urinary tract infection	13.40	10.55	254	52126	274258	79417750
Vaginal haemorrhage	13.39	10.55	38	52342	21779	79670229
Rhabdomyolysis	13.32	10.55	30	52350	103101	79588907
Paraesthesia	13.09	10.55	175	52205	176148	79515860
Flushing	13.06	10.55	101	52279	88167	79603841
Transfusion	12.95	10.55	37	52343	21293	79670715
Migraine	12.88	10.55	100	52280	87393	79604615
Rectal fissure	12.84	10.55	8	52372	967	79691041
Fibromyalgia	12.80	10.55	14	52366	64326	79627682
Laboratory test abnormal	12.74	10.55	44	52336	28004	79664004
Drug resistance	12.55	10.55	6	52374	42207	79649801
Ill-defined disorder	12.39	10.55	15	52365	65860	79626148
Chest pain	12.36	10.55	257	52123	282047	79409961
Heavy menstrual bleeding	12.36	10.55	28	52352	13983	79678025
Tremor	12.29	10.55	168	52212	169915	79522093
Rotator cuff syndrome	12.25	10.55	28	52352	14067	79677941
Discomfort	12.17	10.55	42	52338	125575	79566433
Cardio-respiratory arrest	12.12	10.55	34	52346	108476	79583532
International normalised ratio increased	12.01	10.55	96	52284	84625	79607383
Gamma-glutamyltransferase increased	11.91	10.55	11	52369	54669	79637339
Cardiac disorder	11.90	10.55	79	52301	65678	79626330
Altered state of consciousness	11.89	10.55	7	52373	43815	79648193
Chills	11.88	10.55	159	52221	160075	79531933
Prescribed overdose	11.86	10.55	5	52375	37878	79654130
Neoplasm progression	11.73	10.55	10	52370	51672	79640336
Infective pulmonary exacerbation of cystic fibrosis	11.69	10.55	26	52354	12825	79679183
Infection	11.67	10.55	102	52278	241610	79450398
Diabetes mellitus	11.67	10.55	21	52359	78369	79613639
Laryngeal pain	11.55	10.55	17	52363	6097	79685911
Gait disturbance	11.53	10.55	196	52184	207310	79484698
Febrile neutropenia	11.36	10.55	97	52283	230902	79461106
Insomnia	11.33	10.55	225	52155	244945	79447063
Leukopenia	11.25	10.55	39	52341	116474	79575534
Thrombosis	11.23	10.55	94	52286	84006	79608002
Application site discolouration	11.16	10.55	7	52373	857	79691151
Exposure during pregnancy	11.07	10.55	32	52348	101100	79590908
Injection site nodule	11.01	10.55	13	52367	3767	79688241
Rheumatoid arthritis	10.96	10.55	86	52294	208384	79483624
Disease progression	10.93	10.55	176	52204	184186	79507822
Balance disorder	10.90	10.55	106	52274	98751	79593257
Blister	10.87	10.55	41	52339	119435	79572573
Renal impairment	10.86	10.55	60	52320	157723	79534285
Intestinal dilatation	10.85	10.55	11	52369	2689	79689319
Application site erythema	10.82	10.55	15	52365	5095	79686913
Dry skin	10.73	10.55	79	52301	67916	79624092
Neurotoxicity	10.66	10.55	4	52376	32514	79659494
Rash pruritic	10.61	10.55	82	52298	71547	79620461
Drug eruption	10.60	10.55	8	52372	43927	79648081
Intestinal mucosal hypertrophy	10.59	10.55	5	52375	348	79691660

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A11HA31	ALIMENTARY TRACT AND METABOLISM VITAMINS OTHER PLAIN VITAMIN PREPARATIONS Other plain vitamin preparations
ATC	D03AX04	DERMATOLOGICALS PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS CICATRIZANTS Other cicatrizants
MeSH PA	D018977	Micronutrients
MeSH PA	D014803	Vitamin B Complex
MeSH PA	D014815	Vitamins
CHEBI has role	CHEBI:76924	plant metabolites
CHEBI has role	CHEBI:74530	curare poisoning antidote
CHEBI has role	CHEBI:85234	human blood serum metabolites
CHEBI has role	CHEBI:176497	geroprotectors

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Ascorbic acid deficiency	indication	76169001
Pantothenic acid deficiency	indication	238128006
Methemoglobinemia	off-label use	38959009	DOID:10783
Primary hyperoxaluria	contraindication	17901006	DOID:2977
Kidney disease	contraindication	90708001	DOID:557
Anemia due to enzyme deficiency	contraindication	111577008
Hb SS disease	contraindication	127040003	DOID:10923
Hemochromatosis	contraindication	399187006	DOID:2352

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	4.62	acidic
pKa2	12.98	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
568ET80C3D	UNII
4020312	VUID
N0000178898	NUI
D01082	KEGG_DRUG
4017627	VANDF
4017672	VANDF
4020312	VANDF
4021034	VANDF
4021902	VANDF
C0006710	UMLSCUI
CHEBI:31345	CHEBI
PAU	PDB_CHEM_ID
CHEMBL1901349	ChEMBL_ID
443753	PUBCHEM_CID
CHEMBL1594	ChEMBL_ID
D010205	MESH_DESCRIPTOR_UI
1260	INN_ID
4668	IUPHAR_LIGAND_ID
DB01783	DRUGBANK_ID
1918	RXNORM
5685	MMSL
7440	MMSL
NOCODE	MMSL
001056	NDDF
001057	NDDF
126225001	SNOMEDCT_US
66441000	SNOMEDCT_US
86431009	SNOMEDCT_US
137-08-6	SECONDARY_CAS_RN

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Strovite Forte Caplet	HUMAN PRESCRIPTION DRUG LABEL	19	0642-0204	TABLET, COATED	25 mg	ORAL	UNAPPROVED DRUG OTHER	15 sections
Strovite One Caplets	HUMAN PRESCRIPTION DRUG LABEL	20	0642-0207	TABLET	7.50 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Strovite One Caplets	HUMAN PRESCRIPTION DRUG LABEL	20	0642-0207	TABLET	7.50 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Strovite One Caplets	HUMAN PRESCRIPTION DRUG LABEL	20	0642-0207	TABLET	7.50 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Strovite One Caplets	HUMAN PRESCRIPTION DRUG LABEL	20	0642-0207	TABLET	7.50 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
BACMIN	HUMAN PRESCRIPTION DRUG LABEL	19	0682-3001	TABLET, COATED	25 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
Dialyvite Supreme D	HUMAN PRESCRIPTION DRUG LABEL	13	10542-009	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite Supreme D	HUMAN PRESCRIPTION DRUG LABEL	13	10542-009	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite	HUMAN PRESCRIPTION DRUG LABEL	9	10542-010	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite	HUMAN PRESCRIPTION DRUG LABEL	9	10542-010	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite 5000	HUMAN PRESCRIPTION DRUG LABEL	12	10542-011	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite 5000	HUMAN PRESCRIPTION DRUG LABEL	12	10542-011	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite with Zinc	HUMAN PRESCRIPTION DRUG LABEL	10	10542-012	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite with Zinc	HUMAN PRESCRIPTION DRUG LABEL	10	10542-012	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite 3000	HUMAN PRESCRIPTION DRUG LABEL	12	10542-014	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Dialyvite 3000	HUMAN PRESCRIPTION DRUG LABEL	12	10542-014	TABLET, COATED	10 mg	ORAL	Unapproved drug other	7 sections
Se-Natal 19	HUMAN PRESCRIPTION DRUG LABEL	15	13925-116	TABLET	7 mg	ORAL	unapproved drug other	15 sections
Se-Natal 19	HUMAN PRESCRIPTION DRUG LABEL	15	13925-116	TABLET	7 mg	ORAL	unapproved drug other	15 sections
Se-Natal 19 Chewable	HUMAN PRESCRIPTION DRUG LABEL	14	13925-117	TABLET, CHEWABLE	7 mg	ORAL	unapproved drug other	16 sections
Se-Tan PLUS	HUMAN PRESCRIPTION DRUG LABEL	13	13925-118	CAPSULE, GELATIN COATED	10 mg	ORAL	unapproved drug other	19 sections
Se-Tan PLUS	HUMAN PRESCRIPTION DRUG LABEL	13	13925-118	CAPSULE, GELATIN COATED	10 mg	ORAL	unapproved drug other	19 sections
Quflora FE Pediatric Drops	HUMAN PRESCRIPTION DRUG LABEL	14	15370-102	LIQUID	1 mg	ORAL	UNAPPROVED DRUG OTHER	11 sections
Dialyvite	HUMAN PRESCRIPTION DRUG LABEL	9	17856-0010	TABLET, COATED	10 mg	ORAL	Unapproved drug other	8 sections
Centratex	HUMAN PRESCRIPTION DRUG LABEL	13	23359-100	CAPSULE	10 mg	ORAL	unapproved drug other	13 sections
PNV-Select	HUMAN PRESCRIPTION DRUG LABEL	18	42192-320	TABLET, FILM COATED	6 mg	ORAL	unapproved drug other	10 sections
Multi Vitamin and Mineralvitamin	HUMAN OTC DRUG LABEL	11	51220-2001	TABLET, CHEWABLE	1.50 mg	ORAL	unapproved drug other	16 sections
Concept OB	HUMAN PRESCRIPTION DRUG LABEL	15	52747-620	CAPSULE	7 mg	ORAL	unapproved drug other	13 sections
Concept OB	HUMAN PRESCRIPTION DRUG LABEL	15	52747-620	CAPSULE	7 mg	ORAL	unapproved drug other	13 sections
Concept DHA	HUMAN PRESCRIPTION DRUG LABEL	15	52747-621	CAPSULE, LIQUID FILLED	5 mg	ORAL	unapproved drug other	7 sections
Concept DHA	HUMAN PRESCRIPTION DRUG LABEL	15	52747-621	CAPSULE, LIQUID FILLED	5 mg	ORAL	unapproved drug other	7 sections