panipenem 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| analogues of penicillanic acid antibiotics modified in the five-membered ring | 2053 | 87726-17-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
synthetic cpd; structure given in first source
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 2 | g | P |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| Vd (Volume of distribution) | 0.19 L/kg | Lombardo F, Berellini G, Obach RS |
| CL (Clearance) | 2.60 mL/min/kg | Lombardo F, Berellini G, Obach RS |
| t_half (Half-life) | 0.96 hours | Lombardo F, Berellini G, Obach RS |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01DH55 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE OTHER BETA-LACTAM ANTIBACTERIALS Carbapenems |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.09 | acidic |
| pKa2 | 11.09 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01048 | KEGG_DRUG |
| C0207932 | UMLSCUI |
| CHEBI:7911 | CHEBI |
| CHEMBL339323 | ChEMBL_ID |
| C039536 | MESH_SUPPLEMENTAL_RECORD_UI |
| 72015 | PUBCHEM_CID |
| 12184 | IUPHAR_LIGAND_ID |
| 6749 | INN_ID |
| W9769W09JF | UNII |
| 015306 | NDDF |
| 725725000 | SNOMEDCT_US |
Pharmaceutical products:
None